Rattus norvegicus

41 known processes

Padi4

peptidyl arginine deiminase, type IV

(Aliases: Pdi4)

Padi4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.263
cation transmembrane transport GO:0098655 263 0.212
regulation of ion transport GO:0043269 245 0.201
response to metal ion GO:0010038 253 0.132
inorganic cation transmembrane transport GO:0098662 202 0.132
response to inorganic substance GO:0010035 377 0.130
response to lipopolysaccharide GO:0032496 191 0.126
inorganic ion transmembrane transport GO:0098660 229 0.106
regulation of metal ion transport GO:0010959 118 0.104
regulation of cell proliferation GO:0042127 359 0.099
protein complex assembly GO:0006461 263 0.091
response to interleukin 1 GO:0070555 55 0.090
response to nutrient levels GO:0031667 370 0.088
tissue development GO:0009888 252 0.086
organic acid metabolic process GO:0006082 292 0.086
response to extracellular stimulus GO:0009991 380 0.080
response to carbohydrate GO:0009743 183 0.078
protein complex biogenesis GO:0070271 263 0.076
response to cytokine GO:0034097 215 0.075
multi organism reproductive process GO:0044703 262 0.074
sodium ion transport GO:0006814 82 0.074
positive regulation of transport GO:0051050 245 0.074
single organism reproductive process GO:0044702 297 0.071
immune system process GO:0002376 204 0.071
metal ion transport GO:0030001 289 0.069
carboxylic acid metabolic process GO:0019752 289 0.068
metal ion homeostasis GO:0055065 186 0.064
cellular component biogenesis GO:0044085 368 0.063
response to molecule of bacterial origin GO:0002237 194 0.062
sexual reproduction GO:0019953 148 0.061
regulation of multicellular organismal development GO:2000026 376 0.061
cell cell signaling GO:0007267 335 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.059
response to purine containing compound GO:0014074 126 0.058
homeostatic process GO:0042592 331 0.058
reproductive process GO:0022414 372 0.058
cell projection organization GO:0030030 302 0.056
transmembrane transport GO:0055085 412 0.056
cation transport GO:0006812 382 0.056
response to oxidative stress GO:0006979 186 0.054
ion transmembrane transport GO:0034220 365 0.053
carboxylic acid biosynthetic process GO:0046394 83 0.053
growth GO:0040007 165 0.052
brain development GO:0007420 247 0.052
lipid metabolic process GO:0006629 283 0.051
response to oxygen levels GO:0070482 265 0.050
apoptotic process GO:0006915 381 0.050
regulation of cellular ketone metabolic process GO:0010565 27 0.048
macromolecular complex assembly GO:0065003 273 0.046
response to transition metal nanoparticle GO:1990267 122 0.044
intracellular transport GO:0046907 185 0.044
response to vitamin GO:0033273 131 0.044
secretion GO:0046903 307 0.044
protein oligomerization GO:0051259 191 0.042
positive regulation of secretion GO:0051047 140 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
reproductive system development GO:0061458 128 0.041
chemical homeostasis GO:0048878 292 0.040
ion homeostasis GO:0050801 212 0.040
reproduction GO:0000003 245 0.039
response to peptide GO:1901652 292 0.039
response to biotic stimulus GO:0009607 226 0.038
response to potassium ion GO:0035864 9 0.038
small molecule biosynthetic process GO:0044283 124 0.038
response to wounding GO:0009611 254 0.038
response to monosaccharide GO:0034284 159 0.037
cellular homeostasis GO:0019725 252 0.037
establishment of protein localization GO:0045184 141 0.037
multicellular organism reproduction GO:0032504 233 0.036
anatomical structure morphogenesis GO:0009653 298 0.035
secretion by cell GO:0032940 248 0.035
regulation of neurogenesis GO:0050767 247 0.035
regulation of body fluid levels GO:0050878 90 0.035
response to estrogen GO:0043627 232 0.034
cellular calcium ion homeostasis GO:0006874 160 0.034
positive regulation of cell proliferation GO:0008284 249 0.033
regulation of neuron differentiation GO:0045664 208 0.032
response to organophosphorus GO:0046683 102 0.032
cardiac chamber development GO:0003205 1 0.031
oxoacid metabolic process GO:0043436 290 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
single organism biosynthetic process GO:0044711 342 0.030
response to reactive oxygen species GO:0000302 120 0.030
cellular chemical homeostasis GO:0055082 247 0.030
programmed cell death GO:0012501 392 0.029
gonad development GO:0008406 104 0.029
cellular response to interleukin 1 GO:0071347 37 0.029
response to hexose GO:0009746 144 0.029
developmental process involved in reproduction GO:0003006 159 0.028
heart development GO:0007507 72 0.028
regulation of cellular component organization GO:0051128 368 0.028
cellular response to external stimulus GO:0071496 118 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
positive regulation of ion transport GO:0043270 94 0.027
regulation of cell projection organization GO:0031344 175 0.027
wound healing GO:0042060 122 0.027
cellular response to cytokine stimulus GO:0071345 127 0.027
cellular metal ion homeostasis GO:0006875 172 0.027
monovalent inorganic cation transport GO:0015672 172 0.026
response to camp GO:0051591 91 0.026
neuron development GO:0048666 286 0.026
positive regulation of cellular component organization GO:0051130 200 0.025
response to estradiol GO:0032355 164 0.025
cellular cation homeostasis GO:0030003 180 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of blood circulation GO:1903522 110 0.024
response to mineralocorticoid GO:0051385 49 0.024
chemosensory behavior GO:0007635 2 0.024
response to amino acid GO:0043200 75 0.024
carbohydrate metabolic process GO:0005975 130 0.023
lipid biosynthetic process GO:0008610 128 0.023
response to glucocorticoid GO:0051384 223 0.023
single organism behavior GO:0044708 130 0.022
cation homeostasis GO:0055080 195 0.022
biological adhesion GO:0022610 110 0.022
sensory organ development GO:0007423 74 0.022
neuron differentiation GO:0030182 368 0.022
blood circulation GO:0008015 183 0.022
regulation of blood pressure GO:0008217 83 0.021
response to acid chemical GO:0001101 222 0.021
positive regulation of lipid kinase activity GO:0090218 2 0.021
cellular response to stress GO:0033554 269 0.021
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.021
response to ionizing radiation GO:0010212 59 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
regulation of calcium ion transport GO:0051924 77 0.020
regulation of ion transmembrane transport GO:0034765 121 0.020
regeneration GO:0031099 163 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
regulation of programmed cell death GO:0043067 341 0.020
multicellular organismal signaling GO:0035637 44 0.020
olfactory behavior GO:0042048 2 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
sex differentiation GO:0007548 113 0.020
positive regulation of nervous system development GO:0051962 178 0.020
heart morphogenesis GO:0003007 3 0.020
cardiac ventricle development GO:0003231 1 0.020
central nervous system development GO:0007417 311 0.019
circulatory system development GO:0072359 134 0.019
calcium ion transmembrane transport GO:0070588 70 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
organ morphogenesis GO:0009887 75 0.019
grooming behavior GO:0007625 4 0.019
divalent metal ion transport GO:0070838 132 0.019
regulation of signal transduction GO:0009966 318 0.019
female gonad development GO:0008585 53 0.018
positive regulation of gene expression GO:0010628 244 0.018
regulation of cell differentiation GO:0045595 320 0.018
single organism catabolic process GO:0044712 283 0.018
cellular response to lipid GO:0071396 201 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
Human
response to corticosterone GO:0051412 40 0.018
response to decreased oxygen levels GO:0036293 237 0.017
single organism intracellular transport GO:1902582 166 0.017
organophosphate metabolic process GO:0019637 370 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
cellular component assembly GO:0022607 360 0.017
regulation of system process GO:0044057 208 0.017
leydig cell differentiation GO:0033327 8 0.017
regulation of apoptotic process GO:0042981 335 0.017
response to other organism GO:0051707 220 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
monocarboxylic acid biosynthetic process GO:0072330 48 0.016
cellular response to metal ion GO:0071248 55 0.016
regulation of transmembrane transport GO:0034762 122 0.016
head development GO:0060322 247 0.016
positive regulation of developmental process GO:0051094 283 0.016
protein maturation GO:0051604 68 0.016
cell adhesion GO:0007155 110 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
potassium ion transport GO:0006813 97 0.016
hexose metabolic process GO:0019318 58 0.016
female sex differentiation GO:0046660 59 0.016
response to external biotic stimulus GO:0043207 221 0.016
fatty acid metabolic process GO:0006631 99 0.016
nucleic acid templated transcription GO:0097659 379 0.016
regulation of cell growth GO:0001558 85 0.016
calcium ion homeostasis GO:0055074 162 0.015
multi multicellular organism process GO:0044706 138 0.015
cardiac muscle tissue morphogenesis GO:0055008 1 0.015
development of primary sexual characteristics GO:0045137 107 0.015
regulation of transcription dna templated GO:0006355 374 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
cellular amine metabolic process GO:0044106 38 0.015
positive regulation of cell death GO:0010942 184 0.015
cellular amide metabolic process GO:0043603 44 0.015
response to bacterium GO:0009617 200 0.014
regulation of molecular function GO:0065009 398 0.014
response to food GO:0032094 27 0.014
second messenger mediated signaling GO:0019932 51 0.014
organic acid transport GO:0015849 116 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
acute inflammatory response GO:0002526 58 0.014
aging GO:0007568 241 0.014
proteolysis GO:0006508 175 0.014
intracellular signal transduction GO:0035556 314 0.014
hormone biosynthetic process GO:0042446 25 0.014
muscle tissue morphogenesis GO:0060415 1 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
response to temperature stimulus GO:0009266 94 0.014
acid secretion GO:0046717 48 0.014
neuron projection development GO:0031175 273 0.014
organic anion transport GO:0015711 132 0.014
response to glucose GO:0009749 136 0.013
protein complex subunit organization GO:0071822 302 0.013
regulation of anatomical structure size GO:0090066 135 0.013
circulatory system process GO:0003013 183 0.013
axon development GO:0061564 96 0.013
regulation of nervous system development GO:0051960 264 0.013
tube development GO:0035295 89 0.013
vascular process in circulatory system GO:0003018 96 0.013
epithelium development GO:0060429 96 0.013
positive regulation of signaling GO:0023056 270 0.013
vasoconstriction GO:0042310 54 0.013
cellular ketone metabolic process GO:0042180 51 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
macromolecule localization GO:0033036 252 0.013
hormone metabolic process GO:0042445 69 0.013
response to fungicide GO:0060992 20 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
response to heat GO:0009408 60 0.013
cellular component movement GO:0006928 248 0.013
positive regulation of neurogenesis GO:0050769 165 0.012
regulation of response to external stimulus GO:0032101 106 0.012
negative regulation of cell death GO:0060548 229 0.012
regulation of cellular localization GO:0060341 263 0.012
protein processing GO:0016485 68 0.012
axis specification GO:0009798 4 0.012
neurological system process GO:0050877 219 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
organic acid biosynthetic process GO:0016053 83 0.012
glucose metabolic process GO:0006006 52 0.012
cellular response to inorganic substance GO:0071241 65 0.012
response to growth factor GO:0070848 189 0.012
regulation of rna metabolic process GO:0051252 391 0.012
muscle organ morphogenesis GO:0048644 1 0.012
adult locomotory behavior GO:0008344 4 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of growth GO:0045927 55 0.012
organic substance catabolic process GO:1901575 316 0.012
gamete generation GO:0007276 124 0.012
response to vitamin a GO:0033189 36 0.012
tongue morphogenesis GO:0043587 3 0.012
atp metabolic process GO:0046034 72 0.012
amine metabolic process GO:0009308 38 0.012
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to vitamin e GO:0033197 24 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of amino acid transport GO:0051957 13 0.011
response to osmotic stress GO:0006970 42 0.011
female pregnancy GO:0007565 122 0.011
steroid metabolic process GO:0008202 73 0.011
spermatogenesis GO:0007283 99 0.011
axonogenesis GO:0007409 71 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of secretion by cell GO:1903530 208 0.011
sulfur compound metabolic process GO:0006790 70 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to hydrogen peroxide GO:0042542 89 0.011
response to tumor necrosis factor GO:0034612 56 0.011
kidney development GO:0001822 67 0.011
inflammatory response GO:0006954 150 0.011
multicellular organism growth GO:0035264 1 0.011
digestive system development GO:0055123 41 0.011
rna metabolic process GO:0016070 406 0.011
regulation of blood vessel size GO:0050880 89 0.011
peptide biosynthetic process GO:0043043 3 0.011
protein localization GO:0008104 191 0.011
response to fatty acid GO:0070542 65 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
skeletal system development GO:0001501 41 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
response to mechanical stimulus GO:0009612 134 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
carboxylic acid transport GO:0046942 115 0.010
chromosome segregation GO:0007059 2 0.010
anion transport GO:0006820 178 0.010
myosin filament organization GO:0031033 2 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
positive regulation of cell communication GO:0010647 271 0.010
steroid biosynthetic process GO:0006694 48 0.010
cellular response to mechanical stimulus GO:0071260 48 0.010
response to magnesium ion GO:0032026 20 0.010
cytokine secretion GO:0050663 15 0.010
immune response GO:0006955 104 0.010

Padi4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.027
kidney disease DOID:557 0 0.027
disease of anatomical entity DOID:7 0 0.027
Human
urinary system disease DOID:18 0 0.027
musculoskeletal system disease DOID:17 0 0.025
Human