Rattus norvegicus

0 known processes

Rapgefl1

Rap guanine nucleotide exchange factor (GEF)-like 1

(Aliases: MGC109414)

Rapgefl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.090
transcription dna templated GO:0006351 377 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.060
neuron differentiation GO:0030182 368 0.059
intracellular signal transduction GO:0035556 314 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
rna biosynthetic process GO:0032774 380 0.053
cell projection organization GO:0030030 302 0.051
regulation of rna metabolic process GO:0051252 391 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.048
transcription from rna polymerase ii promoter GO:0006366 252 0.047
lipid metabolic process GO:0006629 283 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
nucleic acid templated transcription GO:0097659 379 0.044
neuron projection development GO:0031175 273 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
regulation of cell projection organization GO:0031344 175 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.041
regulation of phosphate metabolic process GO:0019220 349 0.040
regulation of molecular function GO:0065009 398 0.040
response to nutrient levels GO:0031667 370 0.038
regulation of transcription dna templated GO:0006355 374 0.038
programmed cell death GO:0012501 392 0.038
regulation of multicellular organismal development GO:2000026 376 0.037
regulation of catalytic activity GO:0050790 304 0.037
cellular component assembly GO:0022607 360 0.037
cellular component biogenesis GO:0044085 368 0.037
organelle organization GO:0006996 266 0.036
chemical homeostasis GO:0048878 292 0.036
single organism catabolic process GO:0044712 283 0.035
oxoacid metabolic process GO:0043436 290 0.035
regulation of nervous system development GO:0051960 264 0.033
cellular response to hormone stimulus GO:0032870 247 0.033
purine containing compound catabolic process GO:0072523 138 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
positive regulation of developmental process GO:0051094 283 0.033
positive regulation of phosphorylation GO:0042327 177 0.032
neuron development GO:0048666 286 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
organophosphate metabolic process GO:0019637 370 0.032
cellular ketone metabolic process GO:0042180 51 0.031
single organism reproductive process GO:0044702 297 0.031
regulation of cell differentiation GO:0045595 320 0.031
reproductive process GO:0022414 372 0.030
regulation of programmed cell death GO:0043067 341 0.030
cellular chemical homeostasis GO:0055082 247 0.030
multi organism reproductive process GO:0044703 262 0.030
positive regulation of response to stimulus GO:0048584 285 0.029
cellular homeostasis GO:0019725 252 0.029
positive regulation of cell communication GO:0010647 271 0.029
cell motility GO:0048870 202 0.028
organic acid metabolic process GO:0006082 292 0.028
homeostatic process GO:0042592 331 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
cellular response to stress GO:0033554 269 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
central nervous system development GO:0007417 311 0.028
negative regulation of metabolic process GO:0009892 331 0.027
ras protein signal transduction GO:0007265 29 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
apoptotic process GO:0006915 381 0.027
protein phosphorylation GO:0006468 345 0.027
response to nutrient GO:0007584 248 0.026
regulation of hormone levels GO:0010817 187 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
regulation of signal transduction GO:0009966 318 0.026
multicellular organism reproduction GO:0032504 233 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
regulation of cell development GO:0060284 263 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
purine containing compound metabolic process GO:0072521 253 0.025
response to glucocorticoid GO:0051384 223 0.025
regeneration GO:0031099 163 0.025
organic cyclic compound catabolic process GO:1901361 175 0.024
regulation of neurogenesis GO:0050767 247 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
axis specification GO:0009798 4 0.024
cellular component morphogenesis GO:0032989 155 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
macromolecular complex subunit organization GO:0043933 339 0.023
metal ion transport GO:0030001 289 0.023
nucleotide catabolic process GO:0009166 139 0.023
nucleoside metabolic process GO:0009116 179 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
response to extracellular stimulus GO:0009991 380 0.023
regulation of cellular component organization GO:0051128 368 0.023
regulation of apoptotic process GO:0042981 335 0.022
negative regulation of cell proliferation GO:0008285 119 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
divalent inorganic cation transport GO:0072511 134 0.022
head development GO:0060322 247 0.022
cellular component movement GO:0006928 248 0.022
cytoskeleton organization GO:0007010 111 0.022
regulation of protein metabolic process GO:0051246 289 0.022
ion homeostasis GO:0050801 212 0.021
tissue development GO:0009888 252 0.021
intracellular transport GO:0046907 185 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
regulation of phosphorylation GO:0042325 248 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
macromolecule localization GO:0033036 252 0.021
catabolic process GO:0009056 351 0.021
cation transport GO:0006812 382 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
response to monosaccharide GO:0034284 159 0.020
nucleoside catabolic process GO:0009164 126 0.020
response to inorganic substance GO:0010035 377 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
nucleotide metabolic process GO:0009117 279 0.020
locomotion GO:0040011 237 0.019
macromolecular complex assembly GO:0065003 273 0.019
cell projection morphogenesis GO:0048858 123 0.019
cellular amine metabolic process GO:0044106 38 0.019
regulation of neuron projection development GO:0010975 161 0.019
protein complex biogenesis GO:0070271 263 0.019
growth GO:0040007 165 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
response to wounding GO:0009611 254 0.019
ion transmembrane transport GO:0034220 365 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
response to peptide GO:1901652 292 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
anterior posterior pattern specification GO:0009952 1 0.019
regulation of cell proliferation GO:0042127 359 0.019
protein complex subunit organization GO:0071822 302 0.019
organic substance catabolic process GO:1901575 316 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
negative regulation of cell differentiation GO:0045596 99 0.018
protein complex assembly GO:0006461 263 0.018
negative regulation of gene expression GO:0010629 199 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
organophosphate catabolic process GO:0046434 148 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
positive regulation of cell death GO:0010942 184 0.018
embryonic pattern specification GO:0009880 1 0.018
cell morphogenesis GO:0000902 142 0.018
positive regulation of protein modification process GO:0031401 142 0.018
reproduction GO:0000003 245 0.018
cellular response to steroid hormone stimulus GO:0071383 93 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
dendrite development GO:0016358 72 0.018
negative regulation of nervous system development GO:0051961 79 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
cellular catabolic process GO:0044248 295 0.018
regulation of neuron differentiation GO:0045664 208 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
axon development GO:0061564 96 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
positive regulation of molecular function GO:0044093 230 0.017
response to metal ion GO:0010038 253 0.017
single organism organelle organization GO:1902589 180 0.017
heart morphogenesis GO:0003007 3 0.017
positive regulation of signaling GO:0023056 270 0.017
negative regulation of developmental process GO:0051093 125 0.017
sexual reproduction GO:0019953 148 0.017
carbohydrate metabolic process GO:0005975 130 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of hydrolase activity GO:0051336 143 0.017
regulation of ion transport GO:0043269 245 0.017
response to acid chemical GO:0001101 222 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
positive regulation of gtpase activity GO:0043547 47 0.016
response to peptide hormone GO:0043434 278 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
brain development GO:0007420 247 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
gamete generation GO:0007276 124 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
response to corticosteroid GO:0031960 235 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
protein localization GO:0008104 191 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
single organism intracellular transport GO:1902582 166 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
cellular lipid metabolic process GO:0044255 208 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
divalent metal ion transport GO:0070838 132 0.015
negative regulation of cell development GO:0010721 82 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
positive regulation of cell development GO:0010720 176 0.015
single organism biosynthetic process GO:0044711 342 0.015
epithelium development GO:0060429 96 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
neurological system process GO:0050877 219 0.014
amine metabolic process GO:0009308 38 0.014
cellular response to lipid GO:0071396 201 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
positive regulation of gene expression GO:0010628 244 0.014
cardiac chamber development GO:0003205 1 0.014
developmental process involved in reproduction GO:0003006 159 0.014
calcium ion transport GO:0006816 131 0.014
rho protein signal transduction GO:0007266 11 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
regulation of membrane potential GO:0042391 110 0.014
gtp metabolic process GO:0046039 72 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
regulation of cellular component movement GO:0051270 150 0.014
cell migration GO:0016477 197 0.014
chemosensory behavior GO:0007635 2 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
muscle system process GO:0003012 115 0.014
negative regulation of signaling GO:0023057 157 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of protein modification process GO:0031399 194 0.014
cell cell signaling GO:0007267 335 0.013
response to ethanol GO:0045471 162 0.013
hormone secretion GO:0046879 115 0.013
regulation of metal ion transport GO:0010959 118 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
hormone transport GO:0009914 121 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
negative regulation of molecular function GO:0044092 133 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
response to reactive oxygen species GO:0000302 120 0.013
eye morphogenesis GO:0048592 4 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of cell communication GO:0010648 158 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
regulation of cell motility GO:2000145 131 0.013
dendrite morphogenesis GO:0048813 43 0.013
regulation of catabolic process GO:0009894 113 0.013
regulation of transferase activity GO:0051338 123 0.013
maintenance of location GO:0051235 17 0.013
cytoplasmic transport GO:0016482 115 0.013
localization of cell GO:0051674 202 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of kinase activity GO:0033674 77 0.012
gtp catabolic process GO:0006184 71 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
response to amino acid GO:0043200 75 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
heterocycle catabolic process GO:0046700 167 0.012
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
spindle organization GO:0007051 2 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
monosaccharide metabolic process GO:0005996 61 0.012
establishment of tissue polarity GO:0007164 2 0.012
cellular ion homeostasis GO:0006873 184 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of transport GO:0051051 136 0.011
regulation of kinase activity GO:0043549 117 0.011
hexose metabolic process GO:0019318 58 0.011
hepaticobiliary system development GO:0061008 90 0.011
female gonad development GO:0008585 53 0.011
gastrulation GO:0007369 2 0.011
wound healing GO:0042060 122 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
aromatic compound catabolic process GO:0019439 168 0.011
actin filament based process GO:0030029 86 0.011
regulation of gtpase activity GO:0043087 57 0.011
regulation of cell migration GO:0030334 128 0.011
positive regulation of nervous system development GO:0051962 178 0.011
response to hexose GO:0009746 144 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
regulation of immune system process GO:0002682 123 0.011
cellular macromolecule localization GO:0070727 122 0.011
cell cycle GO:0007049 101 0.011
protein oligomerization GO:0051259 191 0.011
response to ketone GO:1901654 182 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
cation homeostasis GO:0055080 195 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
response to bacterium GO:0009617 200 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
glucose homeostasis GO:0042593 75 0.011
positive regulation of cell motility GO:2000147 97 0.011
action potential GO:0001508 54 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
oxidation reduction process GO:0055114 304 0.011
rna localization GO:0006403 4 0.011
carbohydrate homeostasis GO:0033500 75 0.011
spermatogenesis GO:0007283 99 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.010
secretion GO:0046903 307 0.010
immune response GO:0006955 104 0.010
carboxylic acid transport GO:0046942 115 0.010
response to oxidative stress GO:0006979 186 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
olfactory behavior GO:0042048 2 0.010
cellular protein localization GO:0034613 122 0.010
immune system process GO:0002376 204 0.010
embryonic axis specification GO:0000578 1 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
regulation of response to stress GO:0080134 126 0.010
response to axon injury GO:0048678 59 0.010
sequestering of metal ion GO:0051238 9 0.010
neuronal action potential GO:0019228 35 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.010
cell adhesion GO:0007155 110 0.010
multicellular organism growth GO:0035264 1 0.010

Rapgefl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.012