Rattus norvegicus

13 known processes

Mtnr1a

melatonin receptor 1A

Mtnr1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 235 0.086
regulation of cell proliferation GO:0042127 359 0.077
regulation of locomotion GO:0040012 148 0.067
positive regulation of cell proliferation GO:0008284 249 0.067
regulation of programmed cell death GO:0043067 341 0.053
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.053
Human Rat
neuron differentiation GO:0030182 368 0.049
response to estradiol GO:0032355 164 0.049
aging GO:0007568 241 0.049
purine ribonucleotide metabolic process GO:0009150 227 0.049
Human Rat
regulation of catalytic activity GO:0050790 304 0.047
cellular component assembly GO:0022607 360 0.046
regulation of secretion GO:0051046 224 0.046
Rat
behavior GO:0007610 205 0.046
Rat
regulation of behavior GO:0050795 61 0.045
Rat
cell projection organization GO:0030030 302 0.044
g protein coupled receptor signaling pathway GO:0007186 242 0.044
neuron development GO:0048666 286 0.043
neuron projection development GO:0031175 273 0.042
secretion by cell GO:0032940 248 0.042
Rat
oxoacid metabolic process GO:0043436 290 0.042
rhythmic process GO:0048511 156 0.042
Rat
response to hypoxia GO:0001666 231 0.041
regulation of cell differentiation GO:0045595 320 0.041
regulation of cellular component organization GO:0051128 368 0.040
cell morphogenesis GO:0000902 142 0.040
nucleotide metabolic process GO:0009117 279 0.040
Human Rat
gland development GO:0048732 155 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.038
Rat
protein complex biogenesis GO:0070271 263 0.037
neurological system process GO:0050877 219 0.037
Rat
reproductive process GO:0022414 372 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
organonitrogen compound biosynthetic process GO:1901566 167 0.037
Human
cellular chemical homeostasis GO:0055082 247 0.037
Rat
regulation of hormone levels GO:0010817 187 0.037
Rat
negative regulation of metabolic process GO:0009892 331 0.036
Rat
positive regulation of transport GO:0051050 245 0.036
regulation of ion transport GO:0043269 245 0.035
Rat
protein complex subunit organization GO:0071822 302 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
Human
purine containing compound metabolic process GO:0072521 253 0.034
Human Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
Human
nitrogen compound transport GO:0071705 229 0.033
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
Human
cell cell signaling GO:0007267 335 0.032
Rat
positive regulation of developmental process GO:0051094 283 0.032
response to nutrient levels GO:0031667 370 0.032
organic acid transport GO:0015849 116 0.032
defense response GO:0006952 194 0.032
cellular response to stress GO:0033554 269 0.030
learning or memory GO:0007611 90 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
Human
organic substance catabolic process GO:1901575 316 0.030
single organism behavior GO:0044708 130 0.030
Rat
response to peptide GO:1901652 292 0.030
positive regulation of locomotion GO:0040017 102 0.030
positive regulation of ion transport GO:0043270 94 0.030
memory GO:0007613 54 0.030
cyclic nucleotide biosynthetic process GO:0009190 63 0.030
Human
vesicle mediated transport GO:0016192 181 0.030
cellular amino acid metabolic process GO:0006520 107 0.029
cellular ion homeostasis GO:0006873 184 0.029
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.029
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
ribonucleotide biosynthetic process GO:0009260 85 0.029
Human
response to peptide hormone GO:0043434 278 0.029
anion transport GO:0006820 178 0.028
cation transport GO:0006812 382 0.028
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.028
Human Rat
regulation of apoptotic process GO:0042981 335 0.028
Rat
response to biotic stimulus GO:0009607 226 0.028
calcium ion transport GO:0006816 131 0.028
organophosphate biosynthetic process GO:0090407 143 0.027
Human
cytosolic calcium ion homeostasis GO:0051480 140 0.027
Rat
response to molecule of bacterial origin GO:0002237 194 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
Human Rat
positive regulation of signaling GO:0023056 270 0.027
Rat
multicellular organismal reproductive process GO:0048609 233 0.027
chemical homeostasis GO:0048878 292 0.027
Rat
protein complex assembly GO:0006461 263 0.027
regeneration GO:0031099 163 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
single organism biosynthetic process GO:0044711 342 0.026
Human
reproduction GO:0000003 245 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
Human Rat
regulation of multicellular organismal development GO:2000026 376 0.026
hormone secretion GO:0046879 115 0.026
Rat
response to inorganic substance GO:0010035 377 0.026
cellular homeostasis GO:0019725 252 0.026
Rat
cellular component biogenesis GO:0044085 368 0.026
positive regulation of nervous system development GO:0051962 178 0.026
regulation of protein metabolic process GO:0051246 289 0.026
regulation of hydrolase activity GO:0051336 143 0.026
response to wounding GO:0009611 254 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
Rat
positive regulation of neurogenesis GO:0050769 165 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
cyclic purine nucleotide metabolic process GO:0052652 62 0.025
Human
organic acid metabolic process GO:0006082 292 0.025
regulation of molecular function GO:0065009 398 0.025
Rat
ion homeostasis GO:0050801 212 0.025
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.025
positive regulation of cell communication GO:0010647 271 0.025
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.025
Human Rat
cell projection morphogenesis GO:0048858 123 0.025
locomotion GO:0040011 237 0.025
purine containing compound biosynthetic process GO:0072522 85 0.024
Human
carboxylic acid transport GO:0046942 115 0.024
response to oxygen levels GO:0070482 265 0.024
signal release GO:0023061 145 0.024
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Human
nucleoside metabolic process GO:0009116 179 0.024
protein phosphorylation GO:0006468 345 0.024
programmed cell death GO:0012501 392 0.024
Rat
response to estrogen GO:0043627 232 0.024
response to acid chemical GO:0001101 222 0.024
single organism reproductive process GO:0044702 297 0.024
intracellular signal transduction GO:0035556 314 0.024
organic anion transport GO:0015711 132 0.024
organelle organization GO:0006996 266 0.024
response to corticosteroid GO:0031960 235 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
multicellular organism reproduction GO:0032504 233 0.023
intracellular transport GO:0046907 185 0.023
transcription dna templated GO:0006351 377 0.023
cellular cation homeostasis GO:0030003 180 0.023
Rat
regulation of phosphorylation GO:0042325 248 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
Human Rat
regulation of neurogenesis GO:0050767 247 0.023
cognition GO:0050890 92 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
Rat
regulation of synaptic transmission GO:0050804 141 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.022
Rat
peptide secretion GO:0002790 86 0.022
Rat
response to external biotic stimulus GO:0043207 221 0.022
single organism organelle organization GO:1902589 180 0.022
transmembrane transport GO:0055085 412 0.022
Rat
peptide transport GO:0015833 97 0.022
Rat
response to ethanol GO:0045471 162 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
amine metabolic process GO:0009308 38 0.022
multi organism reproductive process GO:0044703 262 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
Rat
macromolecular complex assembly GO:0065003 273 0.022
cellular component movement GO:0006928 248 0.021
response to other organism GO:0051707 220 0.021
secretion GO:0046903 307 0.021
Rat
cellular response to nitrogen compound GO:1901699 210 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
blood circulation GO:0008015 183 0.021
Rat
ribose phosphate metabolic process GO:0019693 235 0.021
Human Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
positive regulation of molecular function GO:0044093 230 0.021
growth GO:0040007 165 0.021
circulatory system process GO:0003013 183 0.021
Rat
apoptotic process GO:0006915 381 0.021
Rat
positive regulation of response to stimulus GO:0048584 285 0.021
Rat
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.021
Human
ion transmembrane transport GO:0034220 365 0.020
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
Human
neuron neuron synaptic transmission GO:0007270 60 0.020
metal ion transport GO:0030001 289 0.020
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.020
regulation of nervous system development GO:0051960 264 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
localization of cell GO:0051674 202 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
regulation of cellular component movement GO:0051270 150 0.019
purine ribonucleotide biosynthetic process GO:0009152 81 0.019
Human
heart morphogenesis GO:0003007 3 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
Human Rat
lipid metabolic process GO:0006629 283 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
response to metal ion GO:0010038 253 0.019
negative regulation of cell communication GO:0010648 158 0.019
Rat
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.019
Rat
positive regulation of cell development GO:0010720 176 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
response to radiation GO:0009314 137 0.019
organophosphate metabolic process GO:0019637 370 0.019
Human Rat
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
Human
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.019
Human
regulation of anatomical structure size GO:0090066 135 0.019
Rat
response to glucocorticoid GO:0051384 223 0.018
homeostatic process GO:0042592 331 0.018
Rat
chromosome segregation GO:0007059 2 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
regulation of cell migration GO:0030334 128 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
circadian rhythm GO:0007623 88 0.018
Rat
nucleotide biosynthetic process GO:0009165 98 0.018
Human
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
Human
cellular catabolic process GO:0044248 295 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
cellular ketone metabolic process GO:0042180 51 0.018
regulation of hormone secretion GO:0046883 106 0.018
Rat
positive regulation of cell motility GO:2000147 97 0.018
proteolysis GO:0006508 175 0.018
negative regulation of cell death GO:0060548 229 0.018
Rat
regulation of peptide hormone secretion GO:0090276 80 0.017
Rat
cellular response to endogenous stimulus GO:0071495 377 0.017
rna metabolic process GO:0016070 406 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
camp metabolic process GO:0046058 63 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
cellular amine metabolic process GO:0044106 38 0.017
axis specification GO:0009798 4 0.017
regulation of rna metabolic process GO:0051252 391 0.017
response to decreased oxygen levels GO:0036293 237 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
Rat
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.017
Human Rat
cellular response to lipid GO:0071396 201 0.016
protein homooligomerization GO:0051260 91 0.016
hormone transport GO:0009914 121 0.016
Rat
positive regulation of camp metabolic process GO:0030816 31 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
wound healing GO:0042060 122 0.016
camp biosynthetic process GO:0006171 47 0.016
negative regulation of developmental process GO:0051093 125 0.016
response to oxidative stress GO:0006979 186 0.016
cell part morphogenesis GO:0032990 123 0.016
circulatory system development GO:0072359 134 0.016
cellular component morphogenesis GO:0032989 155 0.016
negative regulation of signaling GO:0023057 157 0.016
Rat
developmental process involved in reproduction GO:0003006 159 0.016
negative regulation of programmed cell death GO:0043069 183 0.015
Rat
sexual reproduction GO:0019953 148 0.015
organophosphate catabolic process GO:0046434 148 0.015
response to bacterium GO:0009617 200 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of body fluid levels GO:0050878 90 0.015
macromolecule localization GO:0033036 252 0.015
amide transport GO:0042886 105 0.015
Rat
dephosphorylation GO:0016311 98 0.015
response to ketone GO:1901654 182 0.015
regulation of protein modification process GO:0031399 194 0.015
multicellular organism growth GO:0035264 1 0.015
chemosensory behavior GO:0007635 2 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
Human
regulation of peptide transport GO:0090087 87 0.015
Rat
brain development GO:0007420 247 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
sequestering of metal ion GO:0051238 9 0.015
regulation of neuron death GO:1901214 115 0.015
Rat
cell type specific apoptotic process GO:0097285 134 0.015
Rat
response to extracellular stimulus GO:0009991 380 0.015
response to lipopolysaccharide GO:0032496 191 0.015
olfactory learning GO:0008355 1 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
learning GO:0007612 33 0.014
regulation of cell projection organization GO:0031344 175 0.014
cellular response to external stimulus GO:0071496 118 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
Human
heterocycle catabolic process GO:0046700 167 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
response to ammonium ion GO:0060359 71 0.014
catabolic process GO:0009056 351 0.014
cation homeostasis GO:0055080 195 0.014
Rat
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
Human
regulation of immune system process GO:0002682 123 0.014
female sex differentiation GO:0046660 59 0.014
negative regulation of gene expression GO:0010629 199 0.014
regulation of cell motility GO:2000145 131 0.014
positive regulation of secretion GO:0051047 140 0.014
calcium ion homeostasis GO:0055074 162 0.013
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of secretion GO:0051048 82 0.013
Rat
gastrulation GO:0007369 2 0.013
positive regulation of signal transduction GO:0009967 175 0.013
cellular response to peptide GO:1901653 133 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
regulation of secretion by cell GO:1903530 208 0.013
Rat
organelle localization GO:0051640 55 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
positive regulation of cell death GO:0010942 184 0.013
single organism intracellular transport GO:1902582 166 0.013
heart process GO:0003015 57 0.013
establishment of protein localization GO:0045184 141 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
response to glucose GO:0009749 136 0.013
response to alkaloid GO:0043279 132 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
positive regulation of camp biosynthetic process GO:0030819 28 0.013
positive regulation of gene expression GO:0010628 244 0.013
response to cytokine GO:0034097 215 0.013
developmental growth GO:0048589 100 0.013
regulation of membrane potential GO:0042391 110 0.013
Rat
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.012
Human
regulation of camp metabolic process GO:0030814 43 0.012
cell adhesion GO:0007155 110 0.012
regulation of lyase activity GO:0051339 22 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of cellular localization GO:0060341 263 0.012
Rat
cytoplasmic transport GO:0016482 115 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of cell activation GO:0050865 50 0.012
carbohydrate metabolic process GO:0005975 130 0.012
response to axon injury GO:0048678 59 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
response to hexose GO:0009746 144 0.012
response to growth factor GO:0070848 189 0.012
gamete generation GO:0007276 124 0.012
single organism catabolic process GO:0044712 283 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
Human Rat
regulation of response to wounding GO:1903034 69 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of tube size GO:0035150 89 0.012
Rat
embryonic pattern specification GO:0009880 1 0.012
ovulation cycle GO:0042698 67 0.012
regulation of response to stress GO:0080134 126 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
axonogenesis GO:0007409 71 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
cell motility GO:0048870 202 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
Rat
sleep GO:0030431 30 0.012
Rat
olfactory behavior GO:0042048 2 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
sex differentiation GO:0007548 113 0.012
response to retinoic acid GO:0032526 63 0.012
inflammatory response GO:0006954 150 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
Rat
regulation of blood pressure GO:0008217 83 0.012
urogenital system development GO:0001655 78 0.012
monocarboxylic acid transport GO:0015718 52 0.012
regulation of camp biosynthetic process GO:0030817 38 0.012
negative regulation of response to external stimulus GO:0032102 37 0.012
insulin secretion GO:0030073 69 0.012
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.011
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.011
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
regulation of inflammatory response GO:0050727 48 0.011
regulation of system process GO:0044057 208 0.011
Rat
membrane organization GO:0061024 94 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
response to organophosphorus GO:0046683 102 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
regulation of cell development GO:0060284 263 0.011
central nervous system development GO:0007417 311 0.011
immune system process GO:0002376 204 0.011
cardiovascular system development GO:0072358 134 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
negative regulation of innate immune response GO:0045824 4 0.011
response to electrical stimulus GO:0051602 56 0.011
cell cycle checkpoint GO:0000075 2 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of circadian sleep wake cycle GO:0042749 18 0.011
Rat
ossification GO:0001503 70 0.011
hepaticobiliary system development GO:0061008 90 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
organic acid biosynthetic process GO:0016053 83 0.011
axon development GO:0061564 96 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
Human
cyclic nucleotide metabolic process GO:0009187 80 0.011
Human Rat
negative regulation of homeostatic process GO:0032845 47 0.011
cellular response to histamine GO:0071420 3 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
response to carbohydrate GO:0009743 183 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
atp metabolic process GO:0046034 72 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
Rat
negative regulation of cellular component organization GO:0051129 83 0.011
meiotic cell cycle process GO:1903046 3 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of catabolic process GO:0009894 113 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
spermatogenesis GO:0007283 99 0.010
positive regulation of immune system process GO:0002684 90 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
vascular process in circulatory system GO:0003018 96 0.010
Rat
regulation of cellular component biogenesis GO:0044087 86 0.010
cardiac ventricle development GO:0003231 1 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
regulation of neuron differentiation GO:0045664 208 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
regulation of peptide secretion GO:0002791 82 0.010
Rat
embryonic axis specification GO:0000578 1 0.010
sensory perception GO:0007600 101 0.010
rna localization GO:0006403 4 0.010
nucleoside monophosphate catabolic process GO:0009125 56 0.010
feeding behavior GO:0007631 53 0.010

Mtnr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.010