Rattus norvegicus

0 known processes

Gpr114

G protein-coupled receptor 114

Gpr114 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 320 0.219
organophosphate metabolic process GO:0019637 370 0.140
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.100
response to biotic stimulus GO:0009607 226 0.093
lymphocyte activation GO:0046649 43 0.090
defense response GO:0006952 194 0.087
organic acid metabolic process GO:0006082 292 0.078
regulation of signal transduction GO:0009966 318 0.077
single organism catabolic process GO:0044712 283 0.076
positive regulation of cell proliferation GO:0008284 249 0.075
negative regulation of rna metabolic process GO:0051253 123 0.072
organic substance catabolic process GO:1901575 316 0.071
response to growth factor GO:0070848 189 0.071
positive regulation of response to stimulus GO:0048584 285 0.070
negative regulation of cell death GO:0060548 229 0.069
response to wounding GO:0009611 254 0.068
regulation of cell development GO:0060284 263 0.068
regulation of immune response to tumor cell GO:0002837 3 0.067
rna metabolic process GO:0016070 406 0.066
regulation of molecular function GO:0065009 398 0.065
negative regulation of immune response to tumor cell GO:0002838 2 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.062
response to external biotic stimulus GO:0043207 221 0.058
leukocyte activation GO:0045321 76 0.057
catabolic process GO:0009056 351 0.057
negative regulation of multicellular organismal process GO:0051241 203 0.056
positive regulation of cell differentiation GO:0045597 217 0.055
inflammatory response GO:0006954 150 0.054
response to nutrient levels GO:0031667 370 0.054
negative regulation of cellular metabolic process GO:0031324 281 0.054
regulation of immune system process GO:0002682 123 0.053
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
regulation of cellular localization GO:0060341 263 0.052
response to inorganic substance GO:0010035 377 0.051
regulation of response to stress GO:0080134 126 0.050
cellular catabolic process GO:0044248 295 0.049
reproduction GO:0000003 245 0.049
oxoacid metabolic process GO:0043436 290 0.049
positive regulation of developmental process GO:0051094 283 0.048
intracellular signal transduction GO:0035556 314 0.048
immune response GO:0006955 104 0.048
nucleotide metabolic process GO:0009117 279 0.047
regulation of protein metabolic process GO:0051246 289 0.047
response to extracellular stimulus GO:0009991 380 0.046
negative regulation of metabolic process GO:0009892 331 0.045
single organism reproductive process GO:0044702 297 0.045
regulation of transcription dna templated GO:0006355 374 0.044
cellular ketone metabolic process GO:0042180 51 0.044
cellular nitrogen compound catabolic process GO:0044270 163 0.043
cellular response to stress GO:0033554 269 0.043
cellular response to growth factor stimulus GO:0071363 162 0.042
organic cyclic compound catabolic process GO:1901361 175 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.041
regulation of immunoglobulin production GO:0002637 4 0.041
immune system development GO:0002520 41 0.040
ribose phosphate metabolic process GO:0019693 235 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
cytokine production GO:0001816 61 0.038
positive regulation of neurogenesis GO:0050769 165 0.038
positive regulation of nervous system development GO:0051962 178 0.036
regulation of catalytic activity GO:0050790 304 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
regulation of neuron death GO:1901214 115 0.034
regulation of cell proliferation GO:0042127 359 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
transcription dna templated GO:0006351 377 0.033
response to ethanol GO:0045471 162 0.033
negative regulation of gene expression GO:0010629 199 0.033
negative regulation of response to tumor cell GO:0002835 2 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
regulation of rna metabolic process GO:0051252 391 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.031
rna biosynthetic process GO:0032774 380 0.031
dendrite development GO:0016358 72 0.031
protein complex subunit organization GO:0071822 302 0.031
protein localization GO:0008104 191 0.031
response to other organism GO:0051707 220 0.030
divalent inorganic cation homeostasis GO:0072507 165 0.030
heterocycle catabolic process GO:0046700 167 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
reproductive process GO:0022414 372 0.029
sexual reproduction GO:0019953 148 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
cell cell signaling GO:0007267 335 0.029
ras protein signal transduction GO:0007265 29 0.028
response to estrogen GO:0043627 232 0.028
secretion GO:0046903 307 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
protein phosphorylation GO:0006468 345 0.028
single organism biosynthetic process GO:0044711 342 0.028
macromolecule localization GO:0033036 252 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
regulation of response to external stimulus GO:0032101 106 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
positive regulation of molecular function GO:0044093 230 0.027
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
inflammatory response to antigenic stimulus GO:0002437 18 0.027
nitrogen compound transport GO:0071705 229 0.027
immune effector process GO:0002252 53 0.026
nucleoside metabolic process GO:0009116 179 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
intracellular transport GO:0046907 185 0.026
actin cytoskeleton organization GO:0030036 73 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
brain development GO:0007420 247 0.025
nucleic acid templated transcription GO:0097659 379 0.025
regulation of leukocyte proliferation GO:0070663 26 0.025
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.025
neuron projection development GO:0031175 273 0.025
organophosphate catabolic process GO:0046434 148 0.025
negative regulation of secretion by cell GO:1903531 72 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
multi organism reproductive process GO:0044703 262 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
immune response to tumor cell GO:0002418 3 0.024
positive regulation of signaling GO:0023056 270 0.024
nucleoside catabolic process GO:0009164 126 0.024
regulation of defense response GO:0031347 68 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of nervous system development GO:0051960 264 0.024
immune system process GO:0002376 204 0.024
purine nucleotide metabolic process GO:0006163 229 0.023
cellular amine metabolic process GO:0044106 38 0.023
single organism organelle organization GO:1902589 180 0.023
regulation of cellular component organization GO:0051128 368 0.023
secretion by cell GO:0032940 248 0.023
cellular component assembly GO:0022607 360 0.023
regulation of cell activation GO:0050865 50 0.023
regulation of leukocyte activation GO:0002694 45 0.023
positive regulation of cell communication GO:0010647 271 0.022
negative regulation of defense response GO:0031348 19 0.022
regulation of neuron differentiation GO:0045664 208 0.022
regulation of locomotion GO:0040012 148 0.022
regulation of response to tumor cell GO:0002834 3 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
aromatic compound catabolic process GO:0019439 168 0.022
cellular lipid metabolic process GO:0044255 208 0.022
negative regulation of biosynthetic process GO:0009890 168 0.021
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.021
response to tumor cell GO:0002347 4 0.021
localization of cell GO:0051674 202 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
purine containing compound catabolic process GO:0072523 138 0.020
response to toxic substance GO:0009636 133 0.020
regulation of cell projection organization GO:0031344 175 0.020
synaptic transmission GO:0007268 235 0.020
leukocyte mediated immunity GO:0002443 28 0.020
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.020
organelle organization GO:0006996 266 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
regulation of neurogenesis GO:0050767 247 0.020
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.019
regulation of behavior GO:0050795 61 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
regulation of cellular component movement GO:0051270 150 0.019
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
alcohol metabolic process GO:0006066 77 0.019
response to peptide GO:1901652 292 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
response to starvation GO:0042594 59 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of mononuclear cell proliferation GO:0032944 26 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
cell activation GO:0001775 97 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
cytokine mediated signaling pathway GO:0019221 43 0.018
positive regulation of transcription factor import into nucleus GO:0042993 4 0.018
regulation of protein modification process GO:0031399 194 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
positive regulation of lymphocyte activation GO:0051251 25 0.017
negative regulation of innate immune response GO:0045824 4 0.017
regulation of ras protein signal transduction GO:0046578 45 0.017
learning or memory GO:0007611 90 0.017
blood circulation GO:0008015 183 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
cytoskeleton organization GO:0007010 111 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
regulation of inflammatory response GO:0050727 48 0.017
response to cytokine GO:0034097 215 0.017
positive regulation of leukocyte activation GO:0002696 30 0.017
regulation of hormone levels GO:0010817 187 0.017
proteolysis GO:0006508 175 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
glycosyl compound metabolic process GO:1901657 182 0.016
cell migration GO:0016477 197 0.016
protein modification by small protein conjugation or removal GO:0070647 35 0.016
head development GO:0060322 247 0.016
cell type specific apoptotic process GO:0097285 134 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.016
t cell activation GO:0042110 29 0.016
regulation of lymphocyte proliferation GO:0050670 26 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
response to estradiol GO:0032355 164 0.016
nucleotide catabolic process GO:0009166 139 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
positive regulation of signal transduction GO:0009967 175 0.016
positive regulation of lymphocyte proliferation GO:0050671 20 0.016
homeostatic process GO:0042592 331 0.016
regulation of neuron projection development GO:0010975 161 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.015
behavior GO:0007610 205 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
negative regulation of transport GO:0051051 136 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
dna metabolic process GO:0006259 96 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
response to oxidative stress GO:0006979 186 0.015
hormone secretion GO:0046879 115 0.015
regulation of protein localization GO:0032880 81 0.015
multicellular organism reproduction GO:0032504 233 0.015
positive regulation of gene expression GO:0010628 244 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
aging GO:0007568 241 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
positive regulation of synaptic transmission GO:0050806 62 0.015
regulation of apoptotic process GO:0042981 335 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
regulation of system process GO:0044057 208 0.015
macromolecule catabolic process GO:0009057 58 0.015
central nervous system development GO:0007417 311 0.014
response to metal ion GO:0010038 253 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
positive regulation of protein modification process GO:0031401 142 0.014
negative regulation of immune system process GO:0002683 39 0.014
positive regulation of immunoglobulin production GO:0002639 4 0.014
negative regulation of molecular function GO:0044092 133 0.014
calcium ion homeostasis GO:0055074 162 0.014
single organism intracellular transport GO:1902582 166 0.014
cell cycle GO:0007049 101 0.014
regulation of secretion GO:0051046 224 0.014
cellular homeostasis GO:0019725 252 0.014
protein processing GO:0016485 68 0.014
b cell activation involved in immune response GO:0002312 1 0.014
regulation of immune effector process GO:0002697 32 0.014
regulation of isotype switching GO:0045191 1 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
acute inflammatory response GO:0002526 58 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
cellular response to lipid GO:0071396 201 0.013
negative regulation of secretion GO:0051048 82 0.013
protein transport GO:0015031 132 0.013
cellular macromolecule localization GO:0070727 122 0.013
regulation of dendrite development GO:0050773 59 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
amide transport GO:0042886 105 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular component biogenesis GO:0044085 368 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
axis specification GO:0009798 4 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
mononuclear cell proliferation GO:0032943 29 0.013
regulation of lymphocyte activation GO:0051249 34 0.013
negative regulation of signaling GO:0023057 157 0.012
regulation of programmed cell death GO:0043067 341 0.012
negative regulation of neuron death GO:1901215 69 0.012
single organism cellular localization GO:1902580 102 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
leukocyte proliferation GO:0070661 29 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
gamete generation GO:0007276 124 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
response to hypoxia GO:0001666 231 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
regulation of hydrolase activity GO:0051336 143 0.012
cytoplasmic transport GO:0016482 115 0.012
immunoglobulin mediated immune response GO:0016064 4 0.012
spermatogenesis GO:0007283 99 0.012
cellular protein localization GO:0034613 122 0.012
locomotion GO:0040011 237 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.012
regulation of cytokine production GO:0001817 56 0.012
negative regulation of amine transport GO:0051953 24 0.012
negative regulation of developmental process GO:0051093 125 0.012
response to acid chemical GO:0001101 222 0.012
wound healing GO:0042060 122 0.012
positive regulation of mast cell activation GO:0033005 4 0.012
steroid metabolic process GO:0008202 73 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
regulation of cell migration GO:0030334 128 0.012
positive regulation of response to external stimulus GO:0032103 51 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
cell adhesion GO:0007155 110 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
regulation of immune response GO:0050776 55 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
protein complex biogenesis GO:0070271 263 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
carbohydrate metabolic process GO:0005975 130 0.011
positive regulation of cell activation GO:0050867 34 0.011
b cell mediated immunity GO:0019724 4 0.011
positive regulation of cell death GO:0010942 184 0.011
programmed cell death GO:0012501 392 0.011
positive regulation of isotype switching GO:0045830 1 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
apoptotic process GO:0006915 381 0.011
positive regulation of transport GO:0051050 245 0.011
response to ammonium ion GO:0060359 71 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
small molecule catabolic process GO:0044282 59 0.011
response to insulin GO:0032868 133 0.011
hematopoietic or lymphoid organ development GO:0048534 36 0.010
negative regulation of protein maturation GO:1903318 47 0.010
regulation of phosphorylation GO:0042325 248 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
regulation of immunoglobulin secretion GO:0051023 1 0.010
epithelial cell differentiation GO:0030855 71 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
circulatory system process GO:0003013 183 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
meiotic cell cycle process GO:1903046 3 0.010
positive regulation of interferon gamma production GO:0032729 2 0.010
actin filament based process GO:0030029 86 0.010
exocytosis GO:0006887 60 0.010
tissue development GO:0009888 252 0.010

Gpr114 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.015
central nervous system disease DOID:331 0 0.011
nervous system disease DOID:863 0 0.011