Rattus norvegicus

0 known processes

Porf-2

preoptic regulatory factor-2

(Aliases: Arhgap39,KIAA1688)

Porf-2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.115
transcription dna templated GO:0006351 377 0.087
rna metabolic process GO:0016070 406 0.085
organelle organization GO:0006996 266 0.081
regulation of rna metabolic process GO:0051252 391 0.068
nucleic acid templated transcription GO:0097659 379 0.064
single organism organelle organization GO:1902589 180 0.057
regulation of signal transduction GO:0009966 318 0.057
rna biosynthetic process GO:0032774 380 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
regulation of rna biosynthetic process GO:2001141 381 0.054
catabolic process GO:0009056 351 0.052
regulation of multicellular organismal development GO:2000026 376 0.052
regulation of cellular component organization GO:0051128 368 0.051
protein localization GO:0008104 191 0.049
regulation of transcription dna templated GO:0006355 374 0.047
neuron differentiation GO:0030182 368 0.046
apoptotic process GO:0006915 381 0.043
regulation of protein metabolic process GO:0051246 289 0.041
cellular component assembly GO:0022607 360 0.041
anatomical structure morphogenesis GO:0009653 298 0.041
regulation of nervous system development GO:0051960 264 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.037
protein complex biogenesis GO:0070271 263 0.037
cellular component biogenesis GO:0044085 368 0.037
reproduction GO:0000003 245 0.036
single organism intracellular transport GO:1902582 166 0.036
cytoskeleton organization GO:0007010 111 0.035
single organism reproductive process GO:0044702 297 0.035
multi organism reproductive process GO:0044703 262 0.035
regulation of cell differentiation GO:0045595 320 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
ras protein signal transduction GO:0007265 29 0.034
small gtpase mediated signal transduction GO:0007264 36 0.033
positive regulation of developmental process GO:0051094 283 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
negative regulation of biosynthetic process GO:0009890 168 0.032
regulation of neurogenesis GO:0050767 247 0.032
macromolecular complex subunit organization GO:0043933 339 0.031
cell projection organization GO:0030030 302 0.031
negative regulation of metabolic process GO:0009892 331 0.031
regulation of neuron projection development GO:0010975 161 0.030
regulation of molecular function GO:0065009 398 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
oxoacid metabolic process GO:0043436 290 0.029
growth GO:0040007 165 0.029
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
neuron projection development GO:0031175 273 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
response to inorganic substance GO:0010035 377 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
regulation of apoptotic process GO:0042981 335 0.027
positive regulation of gene expression GO:0010628 244 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
protein complex assembly GO:0006461 263 0.027
cellular component movement GO:0006928 248 0.026
protein complex subunit organization GO:0071822 302 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
intracellular signal transduction GO:0035556 314 0.026
gland development GO:0048732 155 0.026
programmed cell death GO:0012501 392 0.025
regulation of programmed cell death GO:0043067 341 0.025
response to oxygen levels GO:0070482 265 0.025
reproductive process GO:0022414 372 0.024
negative regulation of gene expression GO:0010629 199 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
vesicle mediated transport GO:0016192 181 0.024
organophosphate catabolic process GO:0046434 148 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.023
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
cellular amine metabolic process GO:0044106 38 0.022
cation transmembrane transport GO:0098655 263 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
macromolecular complex assembly GO:0065003 273 0.022
cellular macromolecule localization GO:0070727 122 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
transmembrane transport GO:0055085 412 0.022
developmental process involved in reproduction GO:0003006 159 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
cation transport GO:0006812 382 0.021
neuron death GO:0070997 127 0.021
synaptic transmission GO:0007268 235 0.021
response to nutrient levels GO:0031667 370 0.021
protein phosphorylation GO:0006468 345 0.021
positive regulation of cell development GO:0010720 176 0.021
cellular macromolecular complex assembly GO:0034622 58 0.021
nucleoside metabolic process GO:0009116 179 0.020
gamete generation GO:0007276 124 0.020
macromolecule localization GO:0033036 252 0.020
small molecule biosynthetic process GO:0044283 124 0.020
homeostatic process GO:0042592 331 0.020
neuron projection morphogenesis GO:0048812 122 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
amine metabolic process GO:0009308 38 0.020
organic acid metabolic process GO:0006082 292 0.020
ion transmembrane transport GO:0034220 365 0.020
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
positive regulation of cell death GO:0010942 184 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
dendrite development GO:0016358 72 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
response to extracellular stimulus GO:0009991 380 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of cell development GO:0060284 263 0.019
neuron development GO:0048666 286 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of protein modification process GO:0031399 194 0.019
regeneration GO:0031099 163 0.019
nucleotide metabolic process GO:0009117 279 0.018
regulation of synaptic plasticity GO:0048167 70 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
dephosphorylation GO:0016311 98 0.018
multicellular organism reproduction GO:0032504 233 0.018
sexual reproduction GO:0019953 148 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
positive regulation of nervous system development GO:0051962 178 0.018
cell motility GO:0048870 202 0.017
intracellular transport GO:0046907 185 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
response to hypoxia GO:0001666 231 0.017
spermatogenesis GO:0007283 99 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of neuron differentiation GO:0045664 208 0.017
negative regulation of signaling GO:0023057 157 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
peptidyl tyrosine phosphorylation GO:0018108 72 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
cellular catabolic process GO:0044248 295 0.017
central nervous system development GO:0007417 311 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
negative regulation of cell communication GO:0010648 158 0.017
cell cell signaling GO:0007267 335 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
carboxylic acid metabolic process GO:0019752 289 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
regulation of neuron death GO:1901214 115 0.016
ion homeostasis GO:0050801 212 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
organophosphate metabolic process GO:0019637 370 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cellular ion homeostasis GO:0006873 184 0.016
wound healing GO:0042060 122 0.016
anterior posterior pattern specification GO:0009952 1 0.016
regulation of phosphorylation GO:0042325 248 0.016
cellular protein localization GO:0034613 122 0.015
lipid metabolic process GO:0006629 283 0.015
single organism catabolic process GO:0044712 283 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
organic substance catabolic process GO:1901575 316 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
salivary gland development GO:0007431 3 0.015
neurological system process GO:0050877 219 0.015
actin cytoskeleton organization GO:0030036 73 0.015
response to peptide GO:1901652 292 0.015
aromatic compound catabolic process GO:0019439 168 0.015
response to wounding GO:0009611 254 0.015
male gamete generation GO:0048232 99 0.015
organ morphogenesis GO:0009887 75 0.015
secretion GO:0046903 307 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
response to acid chemical GO:0001101 222 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
cell part morphogenesis GO:0032990 123 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
purine containing compound metabolic process GO:0072521 253 0.014
regulation of anatomical structure size GO:0090066 135 0.014
regulation of synaptic transmission GO:0050804 141 0.014
cell morphogenesis GO:0000902 142 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.014
regulation of kinase activity GO:0043549 117 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to growth factor GO:0070848 189 0.014
actin filament based process GO:0030029 86 0.014
gastrulation GO:0007369 2 0.014
spindle organization GO:0007051 2 0.014
positive regulation of signaling GO:0023056 270 0.014
oxidation reduction process GO:0055114 304 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
protein oligomerization GO:0051259 191 0.014
cellular response to peptide GO:1901653 133 0.014
embryonic pattern specification GO:0009880 1 0.014
negative regulation of developmental process GO:0051093 125 0.014
negative regulation of cell development GO:0010721 82 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
tissue development GO:0009888 252 0.013
response to estrogen GO:0043627 232 0.013
nucleoside catabolic process GO:0009164 126 0.013
maintenance of location GO:0051235 17 0.013
adult locomotory behavior GO:0008344 4 0.013
single organism cellular localization GO:1902580 102 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
chemical homeostasis GO:0048878 292 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
inflammatory response GO:0006954 150 0.013
regulation of body fluid levels GO:0050878 90 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
head development GO:0060322 247 0.013
regulation of cellular localization GO:0060341 263 0.013
negative regulation of cell death GO:0060548 229 0.013
metal ion transport GO:0030001 289 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
cellular lipid metabolic process GO:0044255 208 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
response to ketone GO:1901654 182 0.013
cellular homeostasis GO:0019725 252 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
cellular component morphogenesis GO:0032989 155 0.013
chromosome segregation GO:0007059 2 0.013
response to corticosteroid GO:0031960 235 0.013
establishment of tissue polarity GO:0007164 2 0.013
eye morphogenesis GO:0048592 4 0.013
cell projection morphogenesis GO:0048858 123 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
response to toxic substance GO:0009636 133 0.012
gtp catabolic process GO:0006184 71 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to decreased oxygen levels GO:0036293 237 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
single organism biosynthetic process GO:0044711 342 0.012
regulation of homeostatic process GO:0032844 101 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to nutrient GO:0007584 248 0.012
mitotic spindle organization GO:0007052 2 0.012
immune system process GO:0002376 204 0.012
cognition GO:0050890 92 0.012
arp2 3 complex mediated actin nucleation GO:0034314 2 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of catalytic activity GO:0050790 304 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
learning or memory GO:0007611 90 0.012
gliogenesis GO:0042063 93 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
olfactory learning GO:0008355 1 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.011
response to biotic stimulus GO:0009607 226 0.011
salivary gland morphogenesis GO:0007435 1 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
heterocycle catabolic process GO:0046700 167 0.011
cation homeostasis GO:0055080 195 0.011
aging GO:0007568 241 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
regulation of cellular component movement GO:0051270 150 0.011
mapk cascade GO:0000165 140 0.011
cellular chemical homeostasis GO:0055082 247 0.011
toxin transport GO:1901998 3 0.011
regulation of growth GO:0040008 105 0.011
nitrogen compound transport GO:0071705 229 0.011
response to bacterium GO:0009617 200 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
axis specification GO:0009798 4 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
brain development GO:0007420 247 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
defense response GO:0006952 194 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of system process GO:0044057 208 0.011
mitochondrion organization GO:0007005 35 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
negative regulation of actin nucleation GO:0051126 1 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
response to external biotic stimulus GO:0043207 221 0.010
regulation of transferase activity GO:0051338 123 0.010
membrane organization GO:0061024 94 0.010
response to metal ion GO:0010038 253 0.010
negative regulation of nervous system development GO:0051961 79 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
regulation of ion transport GO:0043269 245 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010

Porf-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.021
disease of cellular proliferation DOID:14566 0 0.017
brain disease DOID:936 0 0.013