Rattus norvegicus

0 known processes

Ctsm

cathepsin M

Ctsm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of molecular function GO:0044093 230 0.135
programmed cell death GO:0012501 392 0.107
Rat
cellular component assembly GO:0022607 360 0.105
macromolecular complex subunit organization GO:0043933 339 0.103
positive regulation of signaling GO:0023056 270 0.098
cellular component biogenesis GO:0044085 368 0.088
regulation of apoptotic process GO:0042981 335 0.085
multi organism reproductive process GO:0044703 262 0.075
Rat
cation transport GO:0006812 382 0.073
protein complex subunit organization GO:0071822 302 0.067
single organism reproductive process GO:0044702 297 0.065
Rat
neuron differentiation GO:0030182 368 0.064
oxoacid metabolic process GO:0043436 290 0.064
apoptotic process GO:0006915 381 0.063
organic acid metabolic process GO:0006082 292 0.062
positive regulation of cell proliferation GO:0008284 249 0.062
positive regulation of cellular component movement GO:0051272 102 0.062
behavior GO:0007610 205 0.061
reproductive process GO:0022414 372 0.058
Rat
protein complex assembly GO:0006461 263 0.058
carboxylic acid metabolic process GO:0019752 289 0.056
regulation of rna metabolic process GO:0051252 391 0.056
regulation of nervous system development GO:0051960 264 0.056
protein oligomerization GO:0051259 191 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.052
regulation of molecular function GO:0065009 398 0.051
locomotion GO:0040011 237 0.051
regulation of catalytic activity GO:0050790 304 0.050
macromolecular complex assembly GO:0065003 273 0.050
multicellular organism reproduction GO:0032504 233 0.050
Rat
regulation of system process GO:0044057 208 0.049
central nervous system development GO:0007417 311 0.048
neurological system process GO:0050877 219 0.048
positive regulation of cell communication GO:0010647 271 0.046
cellular response to endogenous stimulus GO:0071495 377 0.045
positive regulation of nervous system development GO:0051962 178 0.044
response to nutrient levels GO:0031667 370 0.042
Rat
multicellular organismal reproductive process GO:0048609 233 0.042
Rat
cellular response to organic cyclic compound GO:0071407 202 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
regulation of response to external stimulus GO:0032101 106 0.040
positive regulation of cell migration GO:0030335 96 0.040
chemical homeostasis GO:0048878 292 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
cellular component movement GO:0006928 248 0.039
protein complex biogenesis GO:0070271 263 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
defense response GO:0006952 194 0.037
positive regulation of catalytic activity GO:0043085 184 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
organelle organization GO:0006996 266 0.036
memory GO:0007613 54 0.035
secretion GO:0046903 307 0.034
amine metabolic process GO:0009308 38 0.033
transcription dna templated GO:0006351 377 0.033
response to nutrient GO:0007584 248 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
regulation of protein kinase activity GO:0045859 105 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
cell migration GO:0016477 197 0.032
regulation of cellular component movement GO:0051270 150 0.031
positive regulation of cell development GO:0010720 176 0.031
sexual reproduction GO:0019953 148 0.031
Rat
regulation of signal transduction GO:0009966 318 0.031
response to peptide hormone GO:0043434 278 0.030
intracellular signal transduction GO:0035556 314 0.029
regulation of programmed cell death GO:0043067 341 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
cellular ketone metabolic process GO:0042180 51 0.029
muscle system process GO:0003012 115 0.028
positive regulation of signal transduction GO:0009967 175 0.028
regulation of cellular component organization GO:0051128 368 0.028
single organism organelle organization GO:1902589 180 0.028
protein homooligomerization GO:0051260 91 0.028
regulation of protein metabolic process GO:0051246 289 0.027
gamete generation GO:0007276 124 0.027
Rat
positive regulation of cell motility GO:2000147 97 0.027
negative regulation of cell death GO:0060548 229 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.026
response to extracellular stimulus GO:0009991 380 0.026
Rat
neuron development GO:0048666 286 0.026
regulation of cell development GO:0060284 263 0.026
protein phosphorylation GO:0006468 345 0.026
purine containing compound metabolic process GO:0072521 253 0.026
positive regulation of hydrolase activity GO:0051345 86 0.026
cell projection organization GO:0030030 302 0.025
anion transport GO:0006820 178 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
sex differentiation GO:0007548 113 0.025
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
regulation of cell migration GO:0030334 128 0.025
response to peptide GO:1901652 292 0.024
regulation of neuron differentiation GO:0045664 208 0.024
response to oxidative stress GO:0006979 186 0.024
positive regulation of locomotion GO:0040017 102 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
cardiovascular system development GO:0072358 134 0.023
brain development GO:0007420 247 0.023
monocarboxylic acid metabolic process GO:0032787 152 0.022
response to estrogen GO:0043627 232 0.022
regulation of protein modification process GO:0031399 194 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cell motility GO:0048870 202 0.022
neuron projection development GO:0031175 273 0.022
regulation of membrane potential GO:0042391 110 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of protein modification process GO:0031401 142 0.021
response to other organism GO:0051707 220 0.021
response to acid chemical GO:0001101 222 0.021
regulation of organelle organization GO:0033043 80 0.021
regulation of cell differentiation GO:0045595 320 0.021
localization of cell GO:0051674 202 0.020
regulation of hydrolase activity GO:0051336 143 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
cellular amine metabolic process GO:0044106 38 0.020
ion homeostasis GO:0050801 212 0.020
response to external biotic stimulus GO:0043207 221 0.020
sodium ion transport GO:0006814 82 0.019
response to carbohydrate GO:0009743 183 0.019
Rat
regulation of catabolic process GO:0009894 113 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
regulation of locomotion GO:0040012 148 0.019
negative regulation of metabolic process GO:0009892 331 0.019
negative regulation of innate immune response GO:0045824 4 0.019
cellular homeostasis GO:0019725 252 0.019
response to hypoxia GO:0001666 231 0.019
sensory perception GO:0007600 101 0.019
rna metabolic process GO:0016070 406 0.019
reproduction GO:0000003 245 0.019
Rat
rhythmic process GO:0048511 156 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
response to wounding GO:0009611 254 0.019
hormone metabolic process GO:0042445 69 0.019
regulation of anatomical structure size GO:0090066 135 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
synaptic transmission GO:0007268 235 0.019
cellular response to extracellular stimulus GO:0031668 73 0.018
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
regulation of phosphorylation GO:0042325 248 0.018
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.018
regulation of rna biosynthetic process GO:2001141 381 0.017
organic substance catabolic process GO:1901575 316 0.017
response to glucocorticoid GO:0051384 223 0.017
Rat
reproductive system development GO:0061458 128 0.017
Rat
positive regulation of cellular component biogenesis GO:0044089 55 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
nucleic acid templated transcription GO:0097659 379 0.017
regulation of neuron projection development GO:0010975 161 0.017
cellular chemical homeostasis GO:0055082 247 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cytoskeleton organization GO:0007010 111 0.016
response to corticosteroid GO:0031960 235 0.016
Rat
proteolysis GO:0006508 175 0.016
Rat
ovulation cycle GO:0042698 67 0.016
macromolecule localization GO:0033036 252 0.016
actin filament based process GO:0030029 86 0.016
cellular ion homeostasis GO:0006873 184 0.016
metal ion transport GO:0030001 289 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
lipid metabolic process GO:0006629 283 0.016
developmental process involved in reproduction GO:0003006 159 0.016
Rat
monovalent inorganic cation transport GO:0015672 172 0.016
regulation of kinase activity GO:0043549 117 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
response to monosaccharide GO:0034284 159 0.016
Rat
positive regulation of action potential GO:0045760 8 0.015
spermatogenesis GO:0007283 99 0.015
Rat
response to axon injury GO:0048678 59 0.015
multi multicellular organism process GO:0044706 138 0.015
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.015
organ regeneration GO:0031100 101 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of hormone levels GO:0010817 187 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of gene expression GO:0010628 244 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
response to hexose GO:0009746 144 0.015
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
response to alkaloid GO:0043279 132 0.015
single organism catabolic process GO:0044712 283 0.014
epithelial cell proliferation GO:0050673 54 0.014
monosaccharide metabolic process GO:0005996 61 0.014
metal ion homeostasis GO:0055065 186 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
response to glucose GO:0009749 136 0.014
Rat
action potential GO:0001508 54 0.014
regulation of neurogenesis GO:0050767 247 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
inflammatory response GO:0006954 150 0.014
organic anion transport GO:0015711 132 0.014
cell activation GO:0001775 97 0.014
regulation of transferase activity GO:0051338 123 0.014
response to cytokine GO:0034097 215 0.014
circulatory system process GO:0003013 183 0.014
response to oxygen levels GO:0070482 265 0.014
regulation of cell projection organization GO:0031344 175 0.013
carbohydrate metabolic process GO:0005975 130 0.013
sensory organ development GO:0007423 74 0.013
development of primary sexual characteristics GO:0045137 107 0.013
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.013
spindle organization GO:0007051 2 0.013
regulation of secretion by cell GO:1903530 208 0.013
positive regulation of catabolic process GO:0009896 78 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
organic acid transport GO:0015849 116 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regeneration GO:0031099 163 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
male gamete generation GO:0048232 99 0.013
Rat
negative regulation of nervous system development GO:0051961 79 0.013
regulation of ion transport GO:0043269 245 0.013
head development GO:0060322 247 0.013
cellular catabolic process GO:0044248 295 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
palate development GO:0060021 2 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.012
homeostatic process GO:0042592 331 0.012
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
positive regulation of transferase activity GO:0051347 81 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of defense response GO:0031349 37 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cofactor metabolic process GO:0051186 95 0.012
cell part morphogenesis GO:0032990 123 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
rna biosynthetic process GO:0032774 380 0.012
cellular hormone metabolic process GO:0034754 49 0.012
cellular calcium ion homeostasis GO:0006874 160 0.011
growth GO:0040007 165 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cellular response to lipid GO:0071396 201 0.011
cellular response to stress GO:0033554 269 0.011
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
immune system process GO:0002376 204 0.011
carboxylic acid transport GO:0046942 115 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
response to decreased oxygen levels GO:0036293 237 0.011
single organism biosynthetic process GO:0044711 342 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
regulation of response to stress GO:0080134 126 0.011
multicellular organism growth GO:0035264 1 0.011
salivary gland development GO:0007431 3 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
signal release GO:0023061 145 0.011
negative regulation of cell communication GO:0010648 158 0.011
rna localization GO:0006403 4 0.011
embryonic pattern specification GO:0009880 1 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
ovulation cycle process GO:0022602 50 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
ossification GO:0001503 70 0.010
Rat
positive regulation of biosynthetic process GO:0009891 319 0.010
reproductive structure development GO:0048608 128 0.010
Rat
regulation of cell motility GO:2000145 131 0.010
regulation of defense response GO:0031347 68 0.010
response to toxic substance GO:0009636 133 0.010
acute inflammatory response GO:0002526 58 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
smooth muscle cell migration GO:0014909 36 0.010
regulation of peptide transport GO:0090087 87 0.010
negative regulation of gene expression GO:0010629 199 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010

Ctsm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.012
disease of anatomical entity DOID:7 0 0.012