Rattus norvegicus

20 known processes

A1cf

APOBEC1 complementation factor

(Aliases: A1cft,Acf,Apobec-1)

A1cf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of response to stimulus GO:0048584 285 0.305
cellular lipid metabolic process GO:0044255 208 0.292
response to extracellular stimulus GO:0009991 380 0.283
cellular response to oxygen containing compound GO:1901701 386 0.274
response to nutrient levels GO:0031667 370 0.270
single organism biosynthetic process GO:0044711 342 0.267
organic acid metabolic process GO:0006082 292 0.231
protein complex biogenesis GO:0070271 263 0.230
cellular component biogenesis GO:0044085 368 0.193
vitamin d receptor signaling pathway GO:0070561 1 0.192
oxoacid metabolic process GO:0043436 290 0.192
macromolecular complex assembly GO:0065003 273 0.184
carboxylic acid metabolic process GO:0019752 289 0.184
response to biotic stimulus GO:0009607 226 0.182
signal transduction by phosphorylation GO:0023014 144 0.154
lipid metabolic process GO:0006629 283 0.152
regulation of phosphorus metabolic process GO:0051174 349 0.149
cellular component assembly GO:0022607 360 0.148
protein homooligomerization GO:0051260 91 0.147
anion transport GO:0006820 178 0.145
regulation of phosphate metabolic process GO:0019220 349 0.135
response to bacterium GO:0009617 200 0.131
glutathione transport GO:0034635 2 0.124
reproductive process GO:0022414 372 0.120
protein phosphorylation GO:0006468 345 0.117
regulation of molecular function GO:0065009 398 0.115
regulation of phosphorylation GO:0042325 248 0.113
macromolecular complex subunit organization GO:0043933 339 0.112
protein complex subunit organization GO:0071822 302 0.111
positive regulation of cell communication GO:0010647 271 0.106
response to peptide GO:1901652 292 0.105
rhythmic process GO:0048511 156 0.103
microvillus assembly GO:0030033 2 0.103
carboxylic acid transport GO:0046942 115 0.095
lipid localization GO:0010876 62 0.095
protein complex assembly GO:0006461 263 0.092
ion transmembrane transport GO:0034220 365 0.089
transcription dna templated GO:0006351 377 0.087
intracellular signal transduction GO:0035556 314 0.085
monosaccharide metabolic process GO:0005996 61 0.085
response to nutrient GO:0007584 248 0.084
oxidation reduction process GO:0055114 304 0.082
antibiotic transport GO:0042891 2 0.080
response to wounding GO:0009611 254 0.079
developmental process involved in reproduction GO:0003006 159 0.077
response to molecule of bacterial origin GO:0002237 194 0.076
fatty acid metabolic process GO:0006631 99 0.075
cellular response to hormone stimulus GO:0032870 247 0.074
regulation of transcription dna templated GO:0006355 374 0.072
regulation of rna biosynthetic process GO:2001141 381 0.070
positive regulation of signaling GO:0023056 270 0.070
rna metabolic process GO:0016070 406 0.069
response to insulin GO:0032868 133 0.068
response to lipopolysaccharide GO:0032496 191 0.068
response to other organism GO:0051707 220 0.067
hexose metabolic process GO:0019318 58 0.067
regulation of protein kinase activity GO:0045859 105 0.066
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.066
single organism behavior GO:0044708 130 0.064
regulation of signal transduction GO:0009966 318 0.063
reproductive structure development GO:0048608 128 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.063
male germ line stem cell asymmetric division GO:0048133 1 0.062
single organism catabolic process GO:0044712 283 0.062
negative regulation of cellular metabolic process GO:0031324 281 0.061
response to starvation GO:0042594 59 0.061
regulation of kinase activity GO:0043549 117 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
mapk cascade GO:0000165 140 0.056
positive regulation of biosynthetic process GO:0009891 319 0.056
response to acid chemical GO:0001101 222 0.055
protein oligomerization GO:0051259 191 0.055
negative regulation of gene expression GO:0010629 199 0.055
regulation of programmed cell death GO:0043067 341 0.054
regulation of catalytic activity GO:0050790 304 0.054
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.054
sterol homeostasis GO:0055092 3 0.053
small molecule biosynthetic process GO:0044283 124 0.053
response to estradiol GO:0032355 164 0.051
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
response to corticosteroid GO:0031960 235 0.049
cholesterol homeostasis GO:0042632 3 0.049
glucose metabolic process GO:0006006 52 0.048
multi organism reproductive process GO:0044703 262 0.048
regulation of protein phosphorylation GO:0001932 183 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.047
cellular carbohydrate metabolic process GO:0044262 72 0.046
response to mechanical stimulus GO:0009612 134 0.045
hepaticobiliary system development GO:0061008 90 0.045
negative regulation of metabolic process GO:0009892 331 0.045
regeneration GO:0031099 163 0.045
single organism reproductive process GO:0044702 297 0.045
cellular response to insulin stimulus GO:0032869 81 0.045
cellular response to stress GO:0033554 269 0.044
signal release GO:0023061 145 0.044
carbohydrate metabolic process GO:0005975 130 0.043
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.043
secretion GO:0046903 307 0.042
response to decreased oxygen levels GO:0036293 237 0.041
reproductive system development GO:0061458 128 0.040
organic substance catabolic process GO:1901575 316 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
positive regulation of developmental process GO:0051094 283 0.040
lipid biosynthetic process GO:0008610 128 0.040
carboxylic acid biosynthetic process GO:0046394 83 0.039
single organism carbohydrate metabolic process GO:0044723 118 0.039
rna biosynthetic process GO:0032774 380 0.039
regulation of transferase activity GO:0051338 123 0.039
nitrogen compound transport GO:0071705 229 0.039
regulation of apoptotic process GO:0042981 335 0.038
nucleic acid templated transcription GO:0097659 379 0.038
liver development GO:0001889 90 0.038
organophosphate metabolic process GO:0019637 370 0.037
monocarboxylic acid metabolic process GO:0032787 152 0.037
lipid transport GO:0006869 61 0.037
apoptotic process GO:0006915 381 0.037
cellular homeostasis GO:0019725 252 0.037
regulation of rna metabolic process GO:0051252 391 0.037
vitamin a metabolic process GO:0006776 2 0.037
regulation of protein metabolic process GO:0051246 289 0.037
hormone transport GO:0009914 121 0.036
organic anion transport GO:0015711 132 0.036
lauric acid metabolic process GO:0048252 4 0.036
circadian rhythm GO:0007623 88 0.035
positive regulation of transcription dna templated GO:0045893 197 0.035
multicellular organism reproduction GO:0032504 233 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
catabolic process GO:0009056 351 0.034
response to monosaccharide GO:0034284 159 0.034
coenzyme metabolic process GO:0006732 86 0.034
gland development GO:0048732 155 0.034
neuron differentiation GO:0030182 368 0.034
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.033
drug transport GO:0015893 18 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
germline stem cell asymmetric division GO:0098728 1 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.032
regulation of response to stress GO:0080134 126 0.032
regulation of growth GO:0040008 105 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
cofactor metabolic process GO:0051186 95 0.032
organic acid transport GO:0015849 116 0.031
carnitine transport GO:0015879 1 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
tripeptide transport GO:0042939 2 0.030
cellular ketone metabolic process GO:0042180 51 0.030
activation of jak2 kinase activity GO:0042977 2 0.029
carbohydrate biosynthetic process GO:0016051 42 0.029
positive regulation of signal transduction GO:0009967 175 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
behavioral response to nicotine GO:0035095 2 0.029
cellular catabolic process GO:0044248 295 0.029
behavior GO:0007610 205 0.029
thioester metabolic process GO:0035383 28 0.028
positive regulation of protein phosphorylation GO:0001934 135 0.028
regulation of cell differentiation GO:0045595 320 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
peptide transport GO:0015833 97 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
brain development GO:0007420 247 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
monocarboxylic acid transport GO:0015718 52 0.027
organ regeneration GO:0031100 101 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
regulation of protein modification process GO:0031399 194 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.026
multi multicellular organism process GO:0044706 138 0.026
regulation of receptor activity GO:0010469 29 0.025
positive regulation of gene expression GO:0010628 244 0.025
response to external biotic stimulus GO:0043207 221 0.025
cell growth GO:0016049 104 0.025
wound healing GO:0042060 122 0.025
reproduction GO:0000003 245 0.025
regulation of membrane potential GO:0042391 110 0.025
regulation of hormone levels GO:0010817 187 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of map kinase activity GO:0043406 46 0.024
cellular response to peptide GO:1901653 133 0.024
peptidyl amino acid modification GO:0018193 126 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
cellular response to lipid GO:0071396 201 0.024
cellular response to organic cyclic compound GO:0071407 202 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
response to heat GO:0009408 60 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
response to carbohydrate GO:0009743 183 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
response to molecule of fungal origin GO:0002238 3 0.023
activation of protein kinase activity GO:0032147 47 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
female pregnancy GO:0007565 122 0.022
ion homeostasis GO:0050801 212 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
cellular amine metabolic process GO:0044106 38 0.022
pancreatic stellate cell proliferation GO:0072343 2 0.022
regulation of neuron death GO:1901214 115 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
cellular response to external stimulus GO:0071496 118 0.021
negative regulation of cell death GO:0060548 229 0.021
cognition GO:0050890 92 0.021
jak stat cascade GO:0007259 26 0.021
lipid storage GO:0019915 1 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
locomotion GO:0040011 237 0.021
response to reactive oxygen species GO:0000302 120 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
neurological system process GO:0050877 219 0.020
heart morphogenesis GO:0003007 3 0.020
inflammatory response GO:0006954 150 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.020
central nervous system development GO:0007417 311 0.020
cellular glucan metabolic process GO:0006073 23 0.020
glutamate receptor signaling pathway GO:0007215 43 0.020
response to metformin GO:1901558 1 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
sodium independent organic anion transport GO:0043252 2 0.020
positive regulation of protein modification process GO:0031401 142 0.020
modified amino acid transport GO:0072337 12 0.020
generation of precursor metabolites and energy GO:0006091 62 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
response to peptide hormone GO:0043434 278 0.020
transmembrane transport GO:0055085 412 0.019
mesoderm morphogenesis GO:0048332 1 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
gonad development GO:0008406 104 0.019
organelle localization GO:0051640 55 0.019
tube development GO:0035295 89 0.019
aging GO:0007568 241 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
negative regulation of molecular function GO:0044092 133 0.019
organic hydroxy compound transport GO:0015850 77 0.019
tissue development GO:0009888 252 0.018
cellular response to cytokine stimulus GO:0071345 127 0.018
synaptic transmission GO:0007268 235 0.018
alcohol metabolic process GO:0006066 77 0.018
regulation of anatomical structure size GO:0090066 135 0.018
positive regulation of phagocytosis engulfment GO:0060100 4 0.018
cell morphogenesis GO:0000902 142 0.018
defense response GO:0006952 194 0.018
regulation of phagocytosis engulfment GO:0060099 4 0.018
neuron development GO:0048666 286 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
response to estrogen GO:0043627 232 0.017
amide transport GO:0042886 105 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
cellular response to alcohol GO:0097306 87 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
response to temperature stimulus GO:0009266 94 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of glucose metabolic process GO:0010906 23 0.017
regulation of lipid metabolic process GO:0019216 68 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
head development GO:0060322 247 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
sex differentiation GO:0007548 113 0.016
asymmetric stem cell division GO:0098722 2 0.016
organelle organization GO:0006996 266 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of microvillus assembly GO:0032534 1 0.016
response to hypoxia GO:0001666 231 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
bmp signaling pathway GO:0030509 4 0.016
prostaglandin transport GO:0015732 8 0.016
regulation of map kinase activity GO:0043405 53 0.016
cellular response to vitamin e GO:0071306 3 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
organ formation GO:0048645 3 0.016
regulation of carbohydrate metabolic process GO:0006109 41 0.016
glycogen metabolic process GO:0005977 23 0.016
regulation of cellular component organization GO:0051128 368 0.015
fatty acid transport GO:0015908 25 0.015
cell projection organization GO:0030030 302 0.015
axis specification GO:0009798 4 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
positive regulation of molecular function GO:0044093 230 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
mesoderm development GO:0007498 2 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
positive regulation of defense response GO:0031349 37 0.015
regulation of activation of jak2 kinase activity GO:0010534 1 0.015
regulation of system process GO:0044057 208 0.015
response to glucose GO:0009749 136 0.015
unsaturated fatty acid metabolic process GO:0033559 39 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
programmed cell death GO:0012501 392 0.015
response to ionizing radiation GO:0010212 59 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
response to hexose GO:0009746 144 0.015
amine metabolic process GO:0009308 38 0.015
regulation of secretion GO:0051046 224 0.014
neuron projection morphogenesis GO:0048812 122 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
axon regeneration GO:0031103 28 0.014
regulation of cell development GO:0060284 263 0.014
development of primary sexual characteristics GO:0045137 107 0.014
developmental growth GO:0048589 100 0.014
carbohydrate catabolic process GO:0016052 40 0.014
isoprenoid metabolic process GO:0006720 45 0.014
regulation of secretion by cell GO:1903530 208 0.014
growth GO:0040007 165 0.014
intracellular receptor signaling pathway GO:0030522 35 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
heart development GO:0007507 72 0.014
circulatory system process GO:0003013 183 0.014
neuron projection development GO:0031175 273 0.014
cofactor biosynthetic process GO:0051188 28 0.014
response to axon injury GO:0048678 59 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
cation transport GO:0006812 382 0.013
steroid metabolic process GO:0008202 73 0.013
muscle cell proliferation GO:0033002 84 0.013
macromolecule localization GO:0033036 252 0.013
chemical homeostasis GO:0048878 292 0.013
positive regulation of kinase activity GO:0033674 77 0.013
positive regulation of secretion GO:0051047 140 0.013
positive regulation of inflammatory response GO:0050729 24 0.013
proteolysis GO:0006508 175 0.013
nucleotide metabolic process GO:0009117 279 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
positive regulation of protein metabolic process GO:0051247 178 0.012
drug transmembrane transport GO:0006855 13 0.012
response to organophosphorus GO:0046683 102 0.012
intestinal absorption GO:0050892 3 0.012
response to oxygen levels GO:0070482 265 0.012
erythrocyte differentiation GO:0030218 1 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
positive regulation of nervous system development GO:0051962 178 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cell projection assembly GO:0030031 21 0.012
regulation of neurogenesis GO:0050767 247 0.012
energy reserve metabolic process GO:0006112 25 0.012
response to ketone GO:1901654 182 0.012
digestive system development GO:0055123 41 0.012
neuron death GO:0070997 127 0.012
positive regulation of response to wounding GO:1903036 34 0.012
single organism organelle organization GO:1902589 180 0.012
endocytosis GO:0006897 84 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
lipid catabolic process GO:0016042 46 0.011
regulation of hormone secretion GO:0046883 106 0.011
regulation of stress activated mapk cascade GO:0032872 23 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
cell type specific apoptotic process GO:0097285 134 0.011
naphthalene containing compound metabolic process GO:0090420 2 0.011
negative regulation of protein import into nucleus translocation GO:0033159 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
gluconeogenesis GO:0006094 15 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
urogenital system development GO:0001655 78 0.011
mrna transcription GO:0009299 2 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
amino acid transport GO:0006865 70 0.011
digestive tract development GO:0048565 39 0.011
positive regulation of cell development GO:0010720 176 0.011
somatostatin receptor signaling pathway GO:0038169 4 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
hormone secretion GO:0046879 115 0.011
vascular process in circulatory system GO:0003018 96 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of cell size GO:0008361 37 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
response to cytokine GO:0034097 215 0.010
erythrocyte homeostasis GO:0034101 2 0.010
glucose homeostasis GO:0042593 75 0.010
translation GO:0006412 35 0.010
response to alkaloid GO:0043279 132 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
regulation of peptide secretion GO:0002791 82 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
response to purine containing compound GO:0014074 126 0.010
axon development GO:0061564 96 0.010
organic cation transport GO:0015695 11 0.010
protein tetramerization GO:0051262 38 0.010
dna integrity checkpoint GO:0031570 2 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010

A1cf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
nervous system disease DOID:863 0 0.015
disease of anatomical entity DOID:7 0 0.015