Rattus norvegicus

0 known processes

A2bp1

ataxin 2 binding protein 1

A2bp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.221
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.141
anatomical structure morphogenesis GO:0009653 298 0.130
cellular component movement GO:0006928 248 0.101
cardiac muscle cell contraction GO:0086003 10 0.096
protein complex biogenesis GO:0070271 263 0.088
actin mediated cell contraction GO:0070252 12 0.088
regulation of phosphorus metabolic process GO:0051174 349 0.085
neuron apoptotic process GO:0051402 88 0.083
protein complex assembly GO:0006461 263 0.083
neuron differentiation GO:0030182 368 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.075
cellular chemical homeostasis GO:0055082 247 0.072
protein complex subunit organization GO:0071822 302 0.071
cell communication involved in cardiac conduction GO:0086065 2 0.066
macromolecular complex subunit organization GO:0043933 339 0.066
programmed cell death GO:0012501 392 0.065
cellular ion homeostasis GO:0006873 184 0.061
neuron projection development GO:0031175 273 0.061
purine ribonucleotide metabolic process GO:0009150 227 0.059
ion transmembrane transport GO:0034220 365 0.059
cellular response to endogenous stimulus GO:0071495 377 0.057
potassium ion transport GO:0006813 97 0.056
regulation of neuron apoptotic process GO:0043523 83 0.055
macromolecular complex assembly GO:0065003 273 0.055
cellular homeostasis GO:0019725 252 0.055
rna metabolic process GO:0016070 406 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
inorganic cation transmembrane transport GO:0098662 202 0.052
regulation of cellular component movement GO:0051270 150 0.051
motor neuron axon guidance GO:0008045 1 0.051
intracellular signal transduction GO:0035556 314 0.051
positive regulation of developmental process GO:0051094 283 0.050
cation transport GO:0006812 382 0.049
g protein coupled receptor signaling pathway GO:0007186 242 0.047
cellular component biogenesis GO:0044085 368 0.047
cardiac muscle contraction GO:0060048 27 0.045
regulation of organ formation GO:0003156 2 0.045
regulation of intracellular signal transduction GO:1902531 218 0.045
striated muscle contraction GO:0006941 44 0.044
regulation of signal transduction GO:0009966 318 0.044
cell projection organization GO:0030030 302 0.044
apoptotic process GO:0006915 381 0.044
aging GO:0007568 241 0.043
cellular cation homeostasis GO:0030003 180 0.043
regulation of molecular function GO:0065009 398 0.042
regulation of membrane repolarization GO:0060306 1 0.042
response to oxygen levels GO:0070482 265 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.040
cell migration GO:0016477 197 0.040
positive regulation of phosphate metabolic process GO:0045937 262 0.040
transcription dna templated GO:0006351 377 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
regulation of transcription dna templated GO:0006355 374 0.040
response to decreased oxygen levels GO:0036293 237 0.038
regulation of cell development GO:0060284 263 0.038
sequestering of metal ion GO:0051238 9 0.038
membrane repolarization GO:0086009 1 0.037
protein phosphorylation GO:0006468 345 0.037
organophosphate metabolic process GO:0019637 370 0.037
small gtpase mediated signal transduction GO:0007264 36 0.037
cellular component assembly GO:0022607 360 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
cellular response to organonitrogen compound GO:0071417 197 0.036
cellular macromolecule localization GO:0070727 122 0.035
locomotion GO:0040011 237 0.035
neuron development GO:0048666 286 0.035
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.034
homeostatic process GO:0042592 331 0.034
developmental induction GO:0031128 2 0.034
inorganic ion transmembrane transport GO:0098660 229 0.033
cellular response to nitrogen compound GO:1901699 210 0.033
tissue development GO:0009888 252 0.033
metal ion transport GO:0030001 289 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
growth GO:0040007 165 0.033
regulation of rna metabolic process GO:0051252 391 0.033
cell morphogenesis GO:0000902 142 0.032
cell morphogenesis involved in differentiation GO:0000904 119 0.032
positive regulation of phosphorylation GO:0042327 177 0.032
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.031
regulation of canonical wnt signaling pathway GO:0060828 4 0.031
positive regulation of cell proliferation GO:0008284 249 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
regulation of phosphorylation GO:0042325 248 0.030
protein oligomerization GO:0051259 191 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
muscle system process GO:0003012 115 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
cardiovascular system development GO:0072358 134 0.028
negative regulation of cell communication GO:0010648 158 0.028
positive regulation of myoblast proliferation GO:2000288 1 0.027
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.027
regulation of cellular localization GO:0060341 263 0.027
nucleic acid templated transcription GO:0097659 379 0.026
cytoplasmic transport GO:0016482 115 0.026
protein heterooligomerization GO:0051291 89 0.026
rna biosynthetic process GO:0032774 380 0.026
blood circulation GO:0008015 183 0.026
regulation of cardiac muscle contraction GO:0055117 17 0.026
cellular response to peptide GO:1901653 133 0.026
regulation of neuron death GO:1901214 115 0.026
regulation of mapk cascade GO:0043408 116 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
neuron death GO:0070997 127 0.026
heterocycle catabolic process GO:0046700 167 0.026
muscle tissue development GO:0060537 58 0.026
positive regulation of transcription dna templated GO:0045893 197 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
hormone secretion GO:0046879 115 0.025
regulation of cellular component organization GO:0051128 368 0.025
positive regulation of signal transduction GO:0009967 175 0.025
cation transmembrane transport GO:0098655 263 0.025
cell projection morphogenesis GO:0048858 123 0.024
liver development GO:0001889 90 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
multicellular organismal signaling GO:0035637 44 0.024
cellular response to stress GO:0033554 269 0.024
cell growth GO:0016049 104 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
regulation of cardiac muscle cell contraction GO:0086004 11 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
chemical homeostasis GO:0048878 292 0.024
regulation of muscle contraction GO:0006937 53 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of apoptotic process GO:0042981 335 0.023
cellular response to oxygen levels GO:0071453 60 0.023
divalent inorganic cation transport GO:0072511 134 0.023
calcium ion transport GO:0006816 131 0.023
circulatory system development GO:0072359 134 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
response to cytokine GO:0034097 215 0.023
muscle contraction GO:0006936 88 0.023
regulation of striated muscle contraction GO:0006942 21 0.022
negative regulation of signaling GO:0023057 157 0.022
macromolecule localization GO:0033036 252 0.022
regulation of catalytic activity GO:0050790 304 0.022
endoplasmic reticulum to cytosol transport GO:1903513 4 0.022
metal ion homeostasis GO:0055065 186 0.022
striated muscle tissue development GO:0014706 58 0.022
hepaticobiliary system development GO:0061008 90 0.022
regulation of system process GO:0044057 208 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
protein localization GO:0008104 191 0.021
single organism membrane organization GO:0044802 74 0.021
actin filament based movement GO:0030048 16 0.021
positive regulation of molecular function GO:0044093 230 0.021
regulation of metal ion transport GO:0010959 118 0.021
sequestering of calcium ion GO:0051208 8 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of cell differentiation GO:0045595 320 0.021
localization of cell GO:0051674 202 0.021
regulation of cellular response to stress GO:0080135 49 0.021
negative regulation of signal transduction GO:0009968 83 0.021
muscle structure development GO:0061061 87 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of neuron differentiation GO:0045664 208 0.021
regulation of intracellular transport GO:0032386 65 0.020
brain development GO:0007420 247 0.020
Zebrafish
regulation of nervous system development GO:0051960 264 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
single organism intracellular transport GO:1902582 166 0.020
single organism biosynthetic process GO:0044711 342 0.020
cellular protein localization GO:0034613 122 0.020
response to extracellular stimulus GO:0009991 380 0.020
cell motility GO:0048870 202 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.020
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.020
regulation of stem cell differentiation GO:2000736 2 0.019
regulation of protein metabolic process GO:0051246 289 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
autonomic nervous system development GO:0048483 3 0.019
organ induction GO:0001759 1 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
actin filament based process GO:0030029 86 0.019
central nervous system development GO:0007417 311 0.019
Zebrafish
single organism catabolic process GO:0044712 283 0.019
anterior posterior pattern specification GO:0009952 1 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
cell cell signaling GO:0007267 335 0.019
sex differentiation GO:0007548 113 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
response to corticosteroid GO:0031960 235 0.018
regulation of catabolic process GO:0009894 113 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
heart morphogenesis GO:0003007 3 0.018
nucleotide metabolic process GO:0009117 279 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
regulation of membrane potential GO:0042391 110 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
response to toxic substance GO:0009636 133 0.018
negative regulation of peptide hormone secretion GO:0090278 30 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
regulation of homeostatic process GO:0032844 101 0.018
intracellular transport GO:0046907 185 0.018
regulation of actin filament based movement GO:1903115 12 0.017
response to glucocorticoid GO:0051384 223 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
specification of organ identity GO:0010092 2 0.017
organic substance catabolic process GO:1901575 316 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
ras protein signal transduction GO:0007265 29 0.017
male gonad development GO:0008584 59 0.017
appendage morphogenesis GO:0035107 4 0.017
regulation of cellular catabolic process GO:0031329 101 0.016
regulation of purine nucleotide catabolic process GO:0033121 65 0.016
regulation of synaptic transmission GO:0050804 141 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
membrane depolarization during action potential GO:0086010 1 0.016
action potential GO:0001508 54 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
regulation of heart contraction GO:0008016 48 0.016
cell cycle GO:0007049 101 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
positive regulation of ion transport GO:0043270 94 0.016
positive regulation of gene expression GO:0010628 244 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
response to nutrient levels GO:0031667 370 0.015
cation homeostasis GO:0055080 195 0.015
regulation of cell projection organization GO:0031344 175 0.015
negative regulation of cell death GO:0060548 229 0.015
single organism cellular localization GO:1902580 102 0.015
diaphragm contraction GO:0002086 2 0.015
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
neuron projection morphogenesis GO:0048812 122 0.015
detection of visible light GO:0009584 3 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
organophosphate catabolic process GO:0046434 148 0.015
mapk cascade GO:0000165 140 0.015
regulation of programmed cell death GO:0043067 341 0.015
regulation of stress activated mapk cascade GO:0032872 23 0.015
cellular ketone metabolic process GO:0042180 51 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of rna metabolic process GO:0051254 203 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cellular amine metabolic process GO:0044106 38 0.014
cell type specific apoptotic process GO:0097285 134 0.014
heart contraction GO:0060047 57 0.014
positive regulation of renin secretion into blood stream GO:1900135 1 0.014
positive regulation of cell communication GO:0010647 271 0.014
tube development GO:0035295 89 0.014
regulation of muscle system process GO:0090257 79 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
response to inorganic substance GO:0010035 377 0.014
cardiac conduction GO:0061337 2 0.014
response to light stimulus GO:0009416 52 0.014
lipid biosynthetic process GO:0008610 128 0.014
regulation of ion transport GO:0043269 245 0.014
l glutamate import GO:0051938 2 0.014
positive regulation of transport GO:0051050 245 0.013
gland development GO:0048732 155 0.013
axonogenesis GO:0007409 71 0.013
cellular response to external stimulus GO:0071496 118 0.013
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.013
biological adhesion GO:0022610 110 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
response to growth factor GO:0070848 189 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
reproductive system development GO:0061458 128 0.013
muscle organ development GO:0007517 50 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
gonad development GO:0008406 104 0.013
reproductive process GO:0022414 372 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to testosterone GO:0033574 55 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
glucose homeostasis GO:0042593 75 0.013
regulation of protein modification process GO:0031399 194 0.013
reproduction GO:0000003 245 0.013
developmental process involved in reproduction GO:0003006 159 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
blood vessel morphogenesis GO:0048514 58 0.013
single organism reproductive process GO:0044702 297 0.013
axis specification GO:0009798 4 0.013
negative regulation of neuron death GO:1901215 69 0.013
synaptic transmission GO:0007268 235 0.013
adrenergic receptor signaling pathway GO:0071875 9 0.013
neuromuscular process GO:0050905 2 0.013
Mouse
negative regulation of neurogenesis GO:0050768 78 0.013
regulation of transmembrane transport GO:0034762 122 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of cell development GO:0010721 82 0.013
response to hypoxia GO:0001666 231 0.013
ion homeostasis GO:0050801 212 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of hydrolase activity GO:0051336 143 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
establishment of protein localization GO:0045184 141 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
membrane organization GO:0061024 94 0.012
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.012
rhythmic process GO:0048511 156 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cytoskeleton organization GO:0007010 111 0.012
single organism behavior GO:0044708 130 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
female sex differentiation GO:0046660 59 0.012
respiratory system development GO:0060541 45 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
regulation of neurological system process GO:0031644 43 0.012
positive regulation of intracellular transport GO:0032388 39 0.012
cytosolic calcium ion transport GO:0060401 39 0.012
renal system development GO:0072001 67 0.012
regulation of neuron projection development GO:0010975 161 0.012
dephosphorylation GO:0016311 98 0.012
amine metabolic process GO:0009308 38 0.012
positive regulation of growth GO:0045927 55 0.012
positive regulation of protein modification process GO:0031401 142 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
positive regulation of cardiac muscle tissue growth GO:0055023 9 0.012
blood vessel development GO:0001568 69 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
regulation of cell proliferation GO:0042127 359 0.011
response to blue light GO:0009637 1 0.011
embryonic skeletal system development GO:0048706 3 0.011
response to electrical stimulus GO:0051602 56 0.011
cell part morphogenesis GO:0032990 123 0.011
sensory perception GO:0007600 101 0.011
multicellular organism growth GO:0035264 1 0.011
forebrain development GO:0030900 98 0.011
Zebrafish
release of sequestered calcium ion into cytosol GO:0051209 25 0.011
single organism organelle organization GO:1902589 180 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
peptidyl amino acid modification GO:0018193 126 0.011
circadian rhythm GO:0007623 88 0.011
catabolic process GO:0009056 351 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
head development GO:0060322 247 0.011
Zebrafish
membrane hyperpolarization GO:0060081 11 0.011
regulation of developmental growth GO:0048638 45 0.011
negative regulation of nervous system development GO:0051961 79 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
positive regulation of signaling GO:0023056 270 0.011
organ formation GO:0048645 3 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
eye morphogenesis GO:0048592 4 0.011
nucleoside metabolic process GO:0009116 179 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
regulation of hormone levels GO:0010817 187 0.011
negative regulation of hormone secretion GO:0046888 46 0.011
insulin secretion GO:0030073 69 0.011
regulation of cell adhesion GO:0030155 52 0.010
regulation of muscle tissue development GO:1901861 25 0.010
negative regulation of rna splicing GO:0033119 3 0.010
carbohydrate catabolic process GO:0016052 40 0.010
positive regulation of cell development GO:0010720 176 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
rho protein signal transduction GO:0007266 11 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
maintenance of location GO:0051235 17 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of renin secretion into blood stream GO:1900133 1 0.010

A2bp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.048
organ system cancer DOID:0050686 0 0.029
cancer DOID:162 0 0.029
disease of anatomical entity DOID:7 0 0.020
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.016
endocrine system disease DOID:28 0 0.015
neuromuscular disease DOID:440 0 0.011
neuropathy DOID:870 0 0.011