Rattus norvegicus

68 known processes

Acadm

acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain

(Aliases: MCAD)

Acadm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid oxidation GO:0034440 30 0.998
fatty acid beta oxidation GO:0006635 22 0.995
fatty acid oxidation GO:0019395 29 0.994
cellular lipid catabolic process GO:0044242 37 0.994
carboxylic acid catabolic process GO:0046395 49 0.980
small molecule catabolic process GO:0044282 59 0.979
fatty acid catabolic process GO:0009062 26 0.970
oxidation reduction process GO:0055114 304 0.968
monocarboxylic acid metabolic process GO:0032787 152 0.960
lipid modification GO:0030258 52 0.951
organic acid metabolic process GO:0006082 292 0.885
monocarboxylic acid catabolic process GO:0072329 28 0.882
carboxylic acid metabolic process GO:0019752 289 0.839
cellular lipid metabolic process GO:0044255 208 0.834
fatty acid metabolic process GO:0006631 99 0.795
organic acid catabolic process GO:0016054 49 0.787
oxoacid metabolic process GO:0043436 290 0.761
cellular ketone metabolic process GO:0042180 51 0.538
Mouse
regulation of fatty acid oxidation GO:0046320 10 0.538
acyl coa metabolic process GO:0006637 28 0.536
fatty acid biosynthetic process GO:0006633 33 0.497
carnitine metabolic process GO:0009437 3 0.488
Human Mouse
cellular catabolic process GO:0044248 295 0.434
response to nutrient levels GO:0031667 370 0.345
lipid catabolic process GO:0016042 46 0.318
catabolic process GO:0009056 351 0.296
lipid biosynthetic process GO:0008610 128 0.287
long chain fatty acid metabolic process GO:0001676 32 0.282
organic substance catabolic process GO:1901575 316 0.274
single organism catabolic process GO:0044712 283 0.253
regulation of lipid biosynthetic process GO:0046890 38 0.243
cellular component biogenesis GO:0044085 368 0.218
lipid metabolic process GO:0006629 283 0.194
single organism biosynthetic process GO:0044711 342 0.182
Human Mouse
long chain fatty acid import GO:0044539 1 0.169
organic hydroxy compound metabolic process GO:1901615 115 0.157
Human Mouse
protein tetramerization GO:0051262 38 0.157
regulation of fatty acid beta oxidation GO:0031998 8 0.146
protein oligomerization GO:0051259 191 0.138
lipid localization GO:0010876 62 0.136
protein complex subunit organization GO:0071822 302 0.134
protein homotetramerization GO:0051289 25 0.132
retinal metabolic process GO:0042574 3 0.130
regulation of fatty acid metabolic process GO:0019217 18 0.127
cellular response to oxygen containing compound GO:1901701 386 0.127
cellular response to organonitrogen compound GO:0071417 197 0.119
fatty acyl coa metabolic process GO:0035337 1 0.115
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.114
homeostatic process GO:0042592 331 0.111
small molecule biosynthetic process GO:0044283 124 0.108
Human
acetyl coa metabolic process GO:0006084 17 0.106
steroid metabolic process GO:0008202 73 0.103
response to extracellular stimulus GO:0009991 380 0.099
macromolecular complex assembly GO:0065003 273 0.097
cellular hormone metabolic process GO:0034754 49 0.092
response to cytokine GO:0034097 215 0.090
amino acid betaine metabolic process GO:0006577 3 0.088
Human Mouse
protein complex biogenesis GO:0070271 263 0.087
cellular component assembly GO:0022607 360 0.081
fatty acid transmembrane transport GO:1902001 3 0.081
cofactor metabolic process GO:0051186 95 0.080
cholesterol metabolic process GO:0008203 17 0.077
protein homooligomerization GO:0051260 91 0.073
response to monosaccharide GO:0034284 159 0.072
cellular response to endogenous stimulus GO:0071495 377 0.072
generation of precursor metabolites and energy GO:0006091 62 0.070
Mouse
carboxylic acid transport GO:0046942 115 0.069
regulation of cellular localization GO:0060341 263 0.068
anion transport GO:0006820 178 0.067
macromolecular complex subunit organization GO:0043933 339 0.066
cellular response to organic cyclic compound GO:0071407 202 0.066
hormone metabolic process GO:0042445 69 0.065
regulation of cellular ketone metabolic process GO:0010565 27 0.062
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.061
cell projection organization GO:0030030 302 0.059
sterol metabolic process GO:0016125 18 0.059
response to acid chemical GO:0001101 222 0.059
response to peptide GO:1901652 292 0.057
positive regulation of lipid catabolic process GO:0050996 4 0.056
cellular response to nitrogen compound GO:1901699 210 0.055
regulation of cholesterol metabolic process GO:0090181 5 0.055
cellular response to insulin stimulus GO:0032869 81 0.054
regulation of hormone levels GO:0010817 187 0.053
regulation of cell differentiation GO:0045595 320 0.050
organic anion transport GO:0015711 132 0.048
response to inorganic substance GO:0010035 377 0.047
positive regulation of biosynthetic process GO:0009891 319 0.046
cellular response to peptide GO:1901653 133 0.046
neurotransmitter biosynthetic process GO:0042136 2 0.045
programmed cell death GO:0012501 392 0.042
protein complex assembly GO:0006461 263 0.042
negative regulation of metabolic process GO:0009892 331 0.042
regulation of peptide hormone secretion GO:0090276 80 0.041
lipid transport GO:0006869 61 0.041
response to nutrient GO:0007584 248 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.040
regulation of ion transport GO:0043269 245 0.039
leydig cell differentiation GO:0033327 8 0.039
long chain fatty acid transport GO:0015909 14 0.038
monocarboxylic acid biosynthetic process GO:0072330 48 0.038
Human
very long chain fatty acid metabolic process GO:0000038 3 0.037
response to toxic substance GO:0009636 133 0.037
response to peptide hormone GO:0043434 278 0.037
positive regulation of molecular function GO:0044093 230 0.037
progesterone biosynthetic process GO:0006701 3 0.037
negative regulation of signaling GO:0023057 157 0.037
negative regulation of lipid biosynthetic process GO:0051055 2 0.036
organic acid transport GO:0015849 116 0.035
positive regulation of cell communication GO:0010647 271 0.035
response to estrogen GO:0043627 232 0.035
cellular response to peptide hormone stimulus GO:0071375 120 0.035
regulation of cellular catabolic process GO:0031329 101 0.035
central nervous system development GO:0007417 311 0.033
multicellular organismal homeostasis GO:0048871 49 0.033
regulation of catabolic process GO:0009894 113 0.033
tissue development GO:0009888 252 0.032
Mouse
androgen metabolic process GO:0008209 14 0.032
organic acid biosynthetic process GO:0016053 83 0.032
Human
organophosphate metabolic process GO:0019637 370 0.031
brain development GO:0007420 247 0.031
regulation of nervous system development GO:0051960 264 0.031
urogenital system development GO:0001655 78 0.030
cellular amine metabolic process GO:0044106 38 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
gland development GO:0048732 155 0.030
Mouse
negative regulation of transport GO:0051051 136 0.030
negative regulation of cell death GO:0060548 229 0.030
temperature homeostasis GO:0001659 17 0.030
regulation of homeostatic process GO:0032844 101 0.030
positive regulation of lipid biosynthetic process GO:0046889 25 0.029
energy derivation by oxidation of organic compounds GO:0015980 46 0.029
Mouse
cellular response to stress GO:0033554 269 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
positive regulation of fatty acid transport GO:2000193 9 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of secretion by cell GO:1903530 208 0.028
regulation of signal transduction GO:0009966 318 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
positive regulation of fatty acid oxidation GO:0046321 6 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
response to estradiol GO:0032355 164 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
response to carbohydrate GO:0009743 183 0.026
negative regulation of programmed cell death GO:0043069 183 0.025
response to alkaloid GO:0043279 132 0.025
protein phosphorylation GO:0006468 345 0.025
peroxisome organization GO:0007031 6 0.025
negative regulation of fatty acid oxidation GO:0046322 2 0.025
neuron differentiation GO:0030182 368 0.025
alcohol metabolic process GO:0006066 77 0.025
cell morphogenesis GO:0000902 142 0.024
positive regulation of cell development GO:0010720 176 0.024
positive regulation of neuron projection development GO:0010976 99 0.024
single organism organelle organization GO:1902589 180 0.024
response to ethanol GO:0045471 162 0.024
mitotic spindle organization GO:0007052 2 0.024
neuron development GO:0048666 286 0.023
renal system development GO:0072001 67 0.023
regulation of programmed cell death GO:0043067 341 0.023
anion transmembrane transport GO:0098656 77 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
positive regulation of nervous system development GO:0051962 178 0.023
metal ion homeostasis GO:0055065 186 0.023
regulation of catalytic activity GO:0050790 304 0.022
regulation of lipid catabolic process GO:0050994 12 0.022
tube development GO:0035295 89 0.022
regulation of peptide transport GO:0090087 87 0.022
regulation of lipid metabolic process GO:0019216 68 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
neuron projection development GO:0031175 273 0.021
signal release GO:0023061 145 0.021
response to corticosteroid GO:0031960 235 0.021
response to hexose GO:0009746 144 0.020
single organism intracellular transport GO:1902582 166 0.020
response to decreased oxygen levels GO:0036293 237 0.020
peptide secretion GO:0002790 86 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
kidney development GO:0001822 67 0.020
icosanoid metabolic process GO:0006690 38 0.020
regulation of protein serine threonine kinase activity GO:0071900 64 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
cellular response to external stimulus GO:0071496 118 0.019
growth GO:0040007 165 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
ion transmembrane transport GO:0034220 365 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
cellular response to lipoteichoic acid GO:0071223 1 0.019
positive regulation of developmental process GO:0051094 283 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
response to vitamin GO:0033273 131 0.019
branched chain amino acid metabolic process GO:0009081 4 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of phosphorylation GO:0042325 248 0.018
response to reactive oxygen species GO:0000302 120 0.018
response to growth factor GO:0070848 189 0.018
cellular response to xenobiotic stimulus GO:0071466 19 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of intracellular transport GO:0032386 65 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
Human
head development GO:0060322 247 0.018
neuron death GO:0070997 127 0.018
cell cell signaling GO:0007267 335 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of secretion GO:0051046 224 0.017
regulation of triglyceride biosynthetic process GO:0010866 4 0.017
nitrogen compound transport GO:0071705 229 0.017
response to glucocorticoid GO:0051384 223 0.017
secretion GO:0046903 307 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
amine metabolic process GO:0009308 38 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
regulation of neuron differentiation GO:0045664 208 0.017
peptide transport GO:0015833 97 0.016
maintenance of location GO:0051235 17 0.016
very long chain fatty acid catabolic process GO:0042760 2 0.016
thymine metabolic process GO:0019859 2 0.016
response to glucose GO:0009749 136 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
response to oxygen levels GO:0070482 265 0.016
macromolecule localization GO:0033036 252 0.016
sulfur compound metabolic process GO:0006790 70 0.016
progesterone metabolic process GO:0042448 8 0.015
regulation of plasma membrane long chain fatty acid transport GO:0010746 2 0.015
regulation of transmembrane transport GO:0034762 122 0.015
regulation of fatty acid transport GO:2000191 10 0.015
spindle organization GO:0007051 2 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cellular chemical homeostasis GO:0055082 247 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
organelle organization GO:0006996 266 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
regulation of steroid metabolic process GO:0019218 25 0.015
regulation of neurogenesis GO:0050767 247 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
secretion by cell GO:0032940 248 0.014
organic hydroxy compound transport GO:0015850 77 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
cellular response to lipid GO:0071396 201 0.014
response to metal ion GO:0010038 253 0.014
membrane organization GO:0061024 94 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
steroid biosynthetic process GO:0006694 48 0.014
intracellular transport GO:0046907 185 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
unsaturated fatty acid metabolic process GO:0033559 39 0.014
cellular ion homeostasis GO:0006873 184 0.014
udp glucose metabolic process GO:0006011 3 0.014
thioester metabolic process GO:0035383 28 0.014
fatty acid derivative metabolic process GO:1901568 38 0.013
positive regulation of triglyceride metabolic process GO:0090208 4 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of kinase activity GO:0043549 117 0.013
alcohol biosynthetic process GO:0046165 38 0.013
amide transport GO:0042886 105 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of peptide secretion GO:0002791 82 0.013
cellular component morphogenesis GO:0032989 155 0.013
response to insulin GO:0032868 133 0.013
positive regulation of homeostatic process GO:0032846 49 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
regulation of protein modification process GO:0031399 194 0.013
regulation of cell projection organization GO:0031344 175 0.013
regulation of hormone secretion GO:0046883 106 0.013
regulation of anion transport GO:0044070 43 0.013
peptide hormone secretion GO:0030072 84 0.013
response to radiation GO:0009314 137 0.012
kidney epithelium development GO:0072073 19 0.012
nucleic acid templated transcription GO:0097659 379 0.012
c21 steroid hormone metabolic process GO:0008207 14 0.012
neuron apoptotic process GO:0051402 88 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
hormone secretion GO:0046879 115 0.012
regulation of apoptotic process GO:0042981 335 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
regulation of protein metabolic process GO:0051246 289 0.012
purine containing compound metabolic process GO:0072521 253 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cation homeostasis GO:0055080 195 0.012
heart morphogenesis GO:0003007 3 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
coenzyme metabolic process GO:0006732 86 0.012
regulation of molecular function GO:0065009 398 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of insulin secretion GO:0050796 65 0.012
positive regulation of transport GO:0051050 245 0.012
aging GO:0007568 241 0.012
development of primary sexual characteristics GO:0045137 107 0.012
response to fatty acid GO:0070542 65 0.012
regulation of cellular component organization GO:0051128 368 0.012
regulation of neuron projection development GO:0010975 161 0.012
metanephric tubule development GO:0072170 4 0.011
divalent metal ion transport GO:0070838 132 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
inositol trisphosphate biosynthetic process GO:0032959 3 0.011
camera type eye morphogenesis GO:0048593 2 0.011
lipid storage GO:0019915 1 0.011
regulation of transferase activity GO:0051338 123 0.011
multicellular organism reproduction GO:0032504 233 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
response to interleukin 1 GO:0070555 55 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of lipid metabolic process GO:0045834 33 0.011
cellular response to nutrient GO:0031670 30 0.011
fatty acid transport GO:0015908 25 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
xenobiotic metabolic process GO:0006805 19 0.011
response to ketone GO:1901654 182 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
response to oxidative stress GO:0006979 186 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
regulation of body fluid levels GO:0050878 90 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
positive regulation of jak stat cascade GO:0046427 19 0.010
ion homeostasis GO:0050801 212 0.010
positive regulation of protein modification process GO:0031401 142 0.010
anterior posterior pattern specification GO:0009952 1 0.010
single organism reproductive process GO:0044702 297 0.010
regulation of phagocytosis engulfment GO:0060099 4 0.010

Acadm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.068
inherited metabolic disorder DOID:655 0 0.068
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
organic acidemia DOID:0060159 0 0.013
amino acid metabolic disorder DOID:9252 0 0.013
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.010