Rattus norvegicus

62 known processes

Acat1

acetyl-coenzyme A acetyltransferase 1

(Aliases: RATACAL)

Acat1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 304 0.961
oxoacid metabolic process GO:0043436 290 0.902
carboxylic acid metabolic process GO:0019752 289 0.846
fatty acid metabolic process GO:0006631 99 0.796
organic acid metabolic process GO:0006082 292 0.573
energy derivation by oxidation of organic compounds GO:0015980 46 0.557
acyl coa metabolic process GO:0006637 28 0.471
small molecule catabolic process GO:0044282 59 0.466
Rat
generation of precursor metabolites and energy GO:0006091 62 0.444
monocarboxylic acid metabolic process GO:0032787 152 0.432
cellular catabolic process GO:0044248 295 0.388
Rat
response to nutrient levels GO:0031667 370 0.271
coenzyme metabolic process GO:0006732 86 0.211
organic substance catabolic process GO:1901575 316 0.203
Rat
catabolic process GO:0009056 351 0.162
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.150
carboxylic acid catabolic process GO:0046395 49 0.149
organic acid biosynthetic process GO:0016053 83 0.148
cellular ketone metabolic process GO:0042180 51 0.144
response to extracellular stimulus GO:0009991 380 0.138
fatty acid beta oxidation GO:0006635 22 0.116
cofactor metabolic process GO:0051186 95 0.110
cellular respiration GO:0045333 21 0.105
single organism biosynthetic process GO:0044711 342 0.104
protein oligomerization GO:0051259 191 0.102
response to glucocorticoid GO:0051384 223 0.101
branched chain amino acid metabolic process GO:0009081 4 0.099
lipid metabolic process GO:0006629 283 0.098
regulation of molecular function GO:0065009 398 0.097
fatty acid oxidation GO:0019395 29 0.096
response to corticosteroid GO:0031960 235 0.096
monosaccharide metabolic process GO:0005996 61 0.090
protein homotetramerization GO:0051289 25 0.089
response to nutrient GO:0007584 248 0.086
Rat
monocarboxylic acid catabolic process GO:0072329 28 0.080
tricarboxylic acid cycle GO:0006099 11 0.079
regulation of gluconeogenesis GO:0006111 4 0.075
macromolecular complex assembly GO:0065003 273 0.072
cellular lipid catabolic process GO:0044242 37 0.072
cellular amino acid catabolic process GO:0009063 21 0.070
regulation of cellular ketone metabolic process GO:0010565 27 0.069
protein phosphorylation GO:0006468 345 0.068
carbohydrate metabolic process GO:0005975 130 0.068
thioester metabolic process GO:0035383 28 0.068
protein tetramerization GO:0051262 38 0.067
tricarboxylic acid metabolic process GO:0072350 10 0.067
single organism catabolic process GO:0044712 283 0.066
Rat
lipid oxidation GO:0034440 30 0.065
glycosyl compound metabolic process GO:1901657 182 0.061
cellular component biogenesis GO:0044085 368 0.061
branched chain amino acid catabolic process GO:0009083 4 0.060
cellular component morphogenesis GO:0032989 155 0.060
cellular response to stress GO:0033554 269 0.058
homeostatic process GO:0042592 331 0.055
gland development GO:0048732 155 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.053
regulation of cell proliferation GO:0042127 359 0.050
cell projection organization GO:0030030 302 0.050
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
citrate metabolic process GO:0006101 3 0.049
regulation of transferase activity GO:0051338 123 0.049
regulation of multicellular organismal development GO:2000026 376 0.047
negative regulation of metabolic process GO:0009892 331 0.045
lipid catabolic process GO:0016042 46 0.044
organelle organization GO:0006996 266 0.044
Fly
multicellular organism reproduction GO:0032504 233 0.044
response to peptide hormone GO:0043434 278 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
fatty acid biosynthetic process GO:0006633 33 0.042
programmed cell death GO:0012501 392 0.041
sulfur compound metabolic process GO:0006790 70 0.041
single organism organelle organization GO:1902589 180 0.039
Fly
reproductive process GO:0022414 372 0.039
aerobic respiration GO:0009060 13 0.039
purine containing compound metabolic process GO:0072521 253 0.039
protein homooligomerization GO:0051260 91 0.039
cellular component assembly GO:0022607 360 0.038
organic hydroxy compound metabolic process GO:1901615 115 0.038
regulation of catalytic activity GO:0050790 304 0.038
positive regulation of cell proliferation GO:0008284 249 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
cellular carbohydrate metabolic process GO:0044262 72 0.037
cellular lipid metabolic process GO:0044255 208 0.037
nucleotide metabolic process GO:0009117 279 0.036
response to organophosphorus GO:0046683 102 0.036
isocitrate metabolic process GO:0006102 5 0.036
fatty acid catabolic process GO:0009062 26 0.036
regulation of phosphorylation GO:0042325 248 0.035
neuron differentiation GO:0030182 368 0.035
macromolecular complex subunit organization GO:0043933 339 0.034
growth GO:0040007 165 0.034
response to monosaccharide GO:0034284 159 0.034
developmental process involved in reproduction GO:0003006 159 0.033
small molecule biosynthetic process GO:0044283 124 0.032
purine nucleoside metabolic process GO:0042278 169 0.032
single organism reproductive process GO:0044702 297 0.032
muscle system process GO:0003012 115 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
regulation of transcription dna templated GO:0006355 374 0.032
hepaticobiliary system development GO:0061008 90 0.031
liver development GO:0001889 90 0.031
regulation of cell differentiation GO:0045595 320 0.031
apoptotic process GO:0006915 381 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.029
lipid localization GO:0010876 62 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of signal transduction GO:0009966 318 0.029
regulation of neurogenesis GO:0050767 247 0.029
acetyl coa metabolic process GO:0006084 17 0.028
protein complex biogenesis GO:0070271 263 0.028
rhythmic process GO:0048511 156 0.028
positive regulation of molecular function GO:0044093 230 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
nucleoside bisphosphate metabolic process GO:0033865 1 0.027
reproduction GO:0000003 245 0.027
response to toxic substance GO:0009636 133 0.027
single organism carbohydrate metabolic process GO:0044723 118 0.027
regulation of cellular localization GO:0060341 263 0.026
negative regulation of signaling GO:0023057 157 0.026
dicarboxylic acid metabolic process GO:0043648 42 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
lipid modification GO:0030258 52 0.025
rna metabolic process GO:0016070 406 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
regulation of programmed cell death GO:0043067 341 0.024
response to oxygen levels GO:0070482 265 0.024
protein complex subunit organization GO:0071822 302 0.024
cellular amine metabolic process GO:0044106 38 0.023
chemical homeostasis GO:0048878 292 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
anion transport GO:0006820 178 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of protein modification process GO:0031399 194 0.022
regulation of cell projection organization GO:0031344 175 0.022
cofactor biosynthetic process GO:0051188 28 0.022
glycogen metabolic process GO:0005977 23 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
cellular polysaccharide metabolic process GO:0044264 23 0.022
negative regulation of cell communication GO:0010648 158 0.022
ion transmembrane transport GO:0034220 365 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
organophosphate metabolic process GO:0019637 370 0.021
regulation of membrane potential GO:0042391 110 0.021
nucleoside metabolic process GO:0009116 179 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
immune system process GO:0002376 204 0.021
positive regulation of biosynthetic process GO:0009891 319 0.020
regulation of apoptotic process GO:0042981 335 0.020
response to inorganic substance GO:0010035 377 0.020
regulation of cell development GO:0060284 263 0.020
neuron projection development GO:0031175 273 0.020
polysaccharide metabolic process GO:0005976 25 0.020
regulation of neuron differentiation GO:0045664 208 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
organic anion transport GO:0015711 132 0.020
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
response to ketone GO:1901654 182 0.019
regulation of neuron projection development GO:0010975 161 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
reproductive system development GO:0061458 128 0.018
regulation of cellular component organization GO:0051128 368 0.018
response to ethanol GO:0045471 162 0.018
glycogen biosynthetic process GO:0005978 15 0.018
response to carbohydrate GO:0009743 183 0.017
transmembrane transport GO:0055085 412 0.017
response to peptide GO:1901652 292 0.017
positive regulation of protein modification process GO:0031401 142 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
sulfur compound biosynthetic process GO:0044272 19 0.017
intracellular transport GO:0046907 185 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
macromolecule localization GO:0033036 252 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
regulation of fatty acid metabolic process GO:0019217 18 0.017
amine metabolic process GO:0009308 38 0.017
regulation of growth GO:0040008 105 0.017
regulation of kinase activity GO:0043549 117 0.017
monocarboxylic acid biosynthetic process GO:0072330 48 0.017
response to hexose GO:0009746 144 0.016
intracellular signal transduction GO:0035556 314 0.016
response to metal ion GO:0010038 253 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
peptide biosynthetic process GO:0043043 3 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
organ regeneration GO:0031100 101 0.015
negative regulation of cell death GO:0060548 229 0.015
carbohydrate biosynthetic process GO:0016051 42 0.015
glucan metabolic process GO:0044042 23 0.015
response to cold GO:0009409 29 0.015
regeneration GO:0031099 163 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of protein metabolic process GO:0051246 289 0.014
maintenance of location GO:0051235 17 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
organic acid catabolic process GO:0016054 49 0.014
response to camp GO:0051591 91 0.014
regulation of hormone levels GO:0010817 187 0.014
response to purine containing compound GO:0014074 126 0.014
response to temperature stimulus GO:0009266 94 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
hexose metabolic process GO:0019318 58 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
response to oxidative stress GO:0006979 186 0.014
neurological system process GO:0050877 219 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
protein complex assembly GO:0006461 263 0.014
carboxylic acid transport GO:0046942 115 0.014
gonad development GO:0008406 104 0.013
cell morphogenesis GO:0000902 142 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
cell activation GO:0001775 97 0.013
transcription dna templated GO:0006351 377 0.013
positive regulation of cell communication GO:0010647 271 0.013
lipid biosynthetic process GO:0008610 128 0.013
rna biosynthetic process GO:0032774 380 0.013
calcium ion homeostasis GO:0055074 162 0.013
energy reserve metabolic process GO:0006112 25 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
reproductive structure development GO:0048608 128 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular homeostasis GO:0019725 252 0.013
transmission of nerve impulse GO:0019226 42 0.013
response to hypoxia GO:0001666 231 0.012
regulation of secretion GO:0051046 224 0.012
lipid storage GO:0019915 1 0.012
cellular glucan metabolic process GO:0006073 23 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
lipid transport GO:0006869 61 0.012
aging GO:0007568 241 0.012
nucleic acid templated transcription GO:0097659 379 0.012
regulation of protein kinase activity GO:0045859 105 0.012
response to glucose GO:0009749 136 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
circulatory system development GO:0072359 134 0.012
positive regulation of developmental process GO:0051094 283 0.012
regulation of catabolic process GO:0009894 113 0.012
cellular response to lipid GO:0071396 201 0.012
Rat
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of transport GO:0051050 245 0.011
regulation of synaptic transmission GO:0050804 141 0.011
regulation of rna metabolic process GO:0051252 391 0.011
hexose biosynthetic process GO:0019319 15 0.011
spermatogenesis GO:0007283 99 0.011
secretion GO:0046903 307 0.011
organic acid transport GO:0015849 116 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
very long chain fatty acid metabolic process GO:0000038 3 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
central nervous system development GO:0007417 311 0.011
positive regulation of gene expression GO:0010628 244 0.011
sequestering of calcium ion GO:0051208 8 0.011
alcohol metabolic process GO:0006066 77 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
chromosome segregation GO:0007059 2 0.011
heart morphogenesis GO:0003007 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to organonitrogen compound GO:0071417 197 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
metestrus GO:0060210 1 0.010
response to fatty acid GO:0070542 65 0.010
Rat
multi organism reproductive process GO:0044703 262 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
Rat
negative regulation of innate immune response GO:0045824 4 0.010
gamete generation GO:0007276 124 0.010
positive regulation of kinase activity GO:0033674 77 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
cation transport GO:0006812 382 0.010
response to cytokine GO:0034097 215 0.010

Acat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.183
inherited metabolic disorder DOID:655 0 0.183
amino acid metabolic disorder DOID:9252 0 0.175
organic acidemia DOID:0060159 0 0.117
central nervous system disease DOID:331 0 0.012
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012