Rattus norvegicus

20 known processes

Accn5

amiloride-sensitive cation channel 5, intestinal

(Aliases: Blinac,Inac)

Accn5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.244
response to peptide GO:1901652 292 0.220
jak stat cascade GO:0007259 26 0.195
response to external biotic stimulus GO:0043207 221 0.195
tissue development GO:0009888 252 0.176
Rat
transmembrane transport GO:0055085 412 0.175
transcription from rna polymerase ii promoter GO:0006366 252 0.144
regulation of immunoglobulin production GO:0002637 4 0.131
response to inorganic substance GO:0010035 377 0.126
response to extracellular stimulus GO:0009991 380 0.124
positive regulation of signal transduction GO:0009967 175 0.124
positive regulation of response to stimulus GO:0048584 285 0.119
cellular response to growth factor stimulus GO:0071363 162 0.115
response to wounding GO:0009611 254 0.115
Rat
cation transmembrane transport GO:0098655 263 0.115
protein complex subunit organization GO:0071822 302 0.113
response to corticosteroid GO:0031960 235 0.113
single organism reproductive process GO:0044702 297 0.111
reproductive process GO:0022414 372 0.111
response to nutrient levels GO:0031667 370 0.110
macromolecular complex subunit organization GO:0043933 339 0.105
response to biotic stimulus GO:0009607 226 0.101
regulation of molecular function GO:0065009 398 0.101
regulation of signal transduction GO:0009966 318 0.096
regulation of protein metabolic process GO:0051246 289 0.094
regulation of multicellular organismal development GO:2000026 376 0.094
regulation of nucleic acid templated transcription GO:1903506 380 0.092
positive regulation of gene expression GO:0010628 244 0.092
response to oxidative stress GO:0006979 186 0.090
negative regulation of metabolic process GO:0009892 331 0.090
gland development GO:0048732 155 0.086
cellular component biogenesis GO:0044085 368 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.082
cellular component assembly GO:0022607 360 0.082
cellular response to oxygen containing compound GO:1901701 386 0.081
protein complex assembly GO:0006461 263 0.079
regulation of rna biosynthetic process GO:2001141 381 0.078
aging GO:0007568 241 0.076
cellular response to tumor necrosis factor GO:0071356 46 0.074
regeneration GO:0031099 163 0.074
positive regulation of rna biosynthetic process GO:1902680 197 0.071
epithelium development GO:0060429 96 0.071
Rat
positive regulation of cell communication GO:0010647 271 0.071
positive regulation of developmental process GO:0051094 283 0.070
regulation of transcription dna templated GO:0006355 374 0.070
regulation of rna metabolic process GO:0051252 391 0.068
rna biosynthetic process GO:0032774 380 0.068
response to growth factor GO:0070848 189 0.067
ion transmembrane transport GO:0034220 365 0.064
organic anion transport GO:0015711 132 0.063
positive regulation of cell proliferation GO:0008284 249 0.063
transcription dna templated GO:0006351 377 0.062
response to other organism GO:0051707 220 0.061
cation transport GO:0006812 382 0.059
wound healing GO:0042060 122 0.059
Rat
cell projection organization GO:0030030 302 0.058
anion transport GO:0006820 178 0.058
calcium ion homeostasis GO:0055074 162 0.057
immunoglobulin mediated immune response GO:0016064 4 0.056
protein complex biogenesis GO:0070271 263 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.056
chemical homeostasis GO:0048878 292 0.056
negative regulation of cellular biosynthetic process GO:0031327 161 0.055
organ formation GO:0048645 3 0.055
response to bacterium GO:0009617 200 0.054
intracellular signal transduction GO:0035556 314 0.053
negative regulation of nucleic acid templated transcription GO:1903507 117 0.052
regulation of cell differentiation GO:0045595 320 0.052
regulation of phosphate metabolic process GO:0019220 349 0.051
cellular amine metabolic process GO:0044106 38 0.051
anatomical structure morphogenesis GO:0009653 298 0.049
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.049
response to nutrient GO:0007584 248 0.048
organ regeneration GO:0031100 101 0.047
positive regulation of molecular function GO:0044093 230 0.046
regulation of cell proliferation GO:0042127 359 0.046
positive regulation of phosphorus metabolic process GO:0010562 262 0.046
organic acid metabolic process GO:0006082 292 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
cellular response to cytokine stimulus GO:0071345 127 0.044
regulation of anatomical structure morphogenesis GO:0022603 141 0.044
sodium ion transport GO:0006814 82 0.043
ion homeostasis GO:0050801 212 0.043
nucleic acid templated transcription GO:0097659 379 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
regulation of hydrolase activity GO:0051336 143 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
lipid metabolic process GO:0006629 283 0.040
multicellular organism reproduction GO:0032504 233 0.040
positive regulation of transcription dna templated GO:0045893 197 0.039
protein oligomerization GO:0051259 191 0.039
inorganic cation transmembrane transport GO:0098662 202 0.039
cellular response to stress GO:0033554 269 0.039
response to reactive oxygen species GO:0000302 120 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.038
carboxylic acid metabolic process GO:0019752 289 0.038
programmed cell death GO:0012501 392 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
amine metabolic process GO:0009308 38 0.037
macromolecular complex assembly GO:0065003 273 0.037
reproductive system development GO:0061458 128 0.037
response to peptide hormone GO:0043434 278 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
response to estradiol GO:0032355 164 0.035
organic hydroxy compound biosynthetic process GO:1901617 51 0.035
cellular response to lipid GO:0071396 201 0.034
developmental process involved in reproduction GO:0003006 159 0.034
regulation of catalytic activity GO:0050790 304 0.034
regulation of phosphorylation GO:0042325 248 0.034
reproductive structure development GO:0048608 128 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
negative regulation of cell death GO:0060548 229 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
response to estrogen GO:0043627 232 0.034
response to tumor necrosis factor GO:0034612 56 0.034
positive regulation of biosynthetic process GO:0009891 319 0.033
response to fibroblast growth factor GO:0071774 29 0.033
alcohol metabolic process GO:0006066 77 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
regulation of response to stress GO:0080134 126 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
positive regulation of jak stat cascade GO:0046427 19 0.032
cellular response to steroid hormone stimulus GO:0071383 93 0.032
positive regulation of cellular protein metabolic process GO:0032270 167 0.032
regulation of protein modification process GO:0031399 194 0.032
organelle organization GO:0006996 266 0.032
positive regulation of protein metabolic process GO:0051247 178 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
positive regulation of immunoglobulin production GO:0002639 4 0.031
protein phosphorylation GO:0006468 345 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
response to cytokine GO:0034097 215 0.030
nitrogen compound transport GO:0071705 229 0.030
inflammatory response GO:0006954 150 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
epithelial cell differentiation GO:0030855 71 0.029
negative regulation of gene expression GO:0010629 199 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
cellular ion homeostasis GO:0006873 184 0.029
positive regulation of secretion GO:0051047 140 0.028
cell motility GO:0048870 202 0.028
Rat
regulation of neuron projection development GO:0010975 161 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
appendage morphogenesis GO:0035107 4 0.027
regulation of programmed cell death GO:0043067 341 0.027
cellular response to peptide GO:1901653 133 0.027
smooth muscle cell proliferation GO:0048659 77 0.026
neuron projection development GO:0031175 273 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
cellular chemical homeostasis GO:0055082 247 0.026
regulation of organ morphogenesis GO:2000027 22 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.026
cellular lipid metabolic process GO:0044255 208 0.026
positive regulation of cell death GO:0010942 184 0.026
response to glucocorticoid GO:0051384 223 0.025
regulation of cellular component movement GO:0051270 150 0.025
response to radiation GO:0009314 137 0.025
positive regulation of nervous system development GO:0051962 178 0.025
cell cell signaling GO:0007267 335 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
positive regulation of protein modification process GO:0031401 142 0.024
oxoacid metabolic process GO:0043436 290 0.024
localization of cell GO:0051674 202 0.024
Rat
growth GO:0040007 165 0.024
rna metabolic process GO:0016070 406 0.024
regulation of locomotion GO:0040012 148 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.023
multi organism reproductive process GO:0044703 262 0.023
developmental induction GO:0031128 2 0.023
organic hydroxy compound transport GO:0015850 77 0.023
reproduction GO:0000003 245 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
response to toxic substance GO:0009636 133 0.023
sex differentiation GO:0007548 113 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
regulation of neuron differentiation GO:0045664 208 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.023
regulation of anatomical structure size GO:0090066 135 0.023
secretion by cell GO:0032940 248 0.023
response to ethanol GO:0045471 162 0.022
response to lipopolysaccharide GO:0032496 191 0.022
response to ionizing radiation GO:0010212 59 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of signaling GO:0023056 270 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
cellular response to corticosteroid stimulus GO:0071384 69 0.022
development of primary sexual characteristics GO:0045137 107 0.022
regulation of cell development GO:0060284 263 0.022
regulation of cell projection organization GO:0031344 175 0.022
single organism biosynthetic process GO:0044711 342 0.021
organic hydroxy compound metabolic process GO:1901615 115 0.021
hindlimb morphogenesis GO:0035137 2 0.021
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.021
head development GO:0060322 247 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cellular homeostasis GO:0019725 252 0.021
negative regulation of molecular function GO:0044092 133 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
organ morphogenesis GO:0009887 75 0.021
regulation of protein maturation GO:1903317 50 0.020
regulation of protein localization GO:0032880 81 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
response to hydrogen peroxide GO:0042542 89 0.020
acute inflammatory response GO:0002526 58 0.020
glycerolipid metabolic process GO:0046486 67 0.020
protein maturation GO:0051604 68 0.019
response to vitamin GO:0033273 131 0.019
regulation of cellular localization GO:0060341 263 0.019
cellular ketone metabolic process GO:0042180 51 0.019
response to transforming growth factor beta GO:0071559 46 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
sexual reproduction GO:0019953 148 0.019
positive regulation of cell development GO:0010720 176 0.019
cytokine production GO:0001816 61 0.019
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
regulation of smooth muscle cell proliferation GO:0048660 75 0.019
cellular response to alcohol GO:0097306 87 0.019
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.019
ossification GO:0001503 70 0.019
response to organophosphorus GO:0046683 102 0.018
vitamin d metabolic process GO:0042359 4 0.018
lipid biosynthetic process GO:0008610 128 0.018
response to oxygen levels GO:0070482 265 0.018
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
tube development GO:0035295 89 0.018
gonad development GO:0008406 104 0.018
action potential GO:0001508 54 0.018
regulation of jak stat cascade GO:0046425 21 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
regulation of ion transport GO:0043269 245 0.018
Rat
mapk cascade GO:0000165 140 0.018
regulation of apoptotic process GO:0042981 335 0.018
lipid transport GO:0006869 61 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
response to insulin GO:0032868 133 0.017
salivary gland development GO:0007431 3 0.017
hepaticobiliary system development GO:0061008 90 0.017
b cell activation involved in immune response GO:0002312 1 0.017
steroid biosynthetic process GO:0006694 48 0.017
male sex differentiation GO:0046661 64 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
immune effector process GO:0002252 53 0.017
synaptic transmission GO:0007268 235 0.017
female gonad development GO:0008585 53 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of secretion GO:0051046 224 0.017
defense response GO:0006952 194 0.017
negative regulation of transport GO:0051051 136 0.017
sulfur compound transport GO:0072348 8 0.016
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.016
protein localization GO:0008104 191 0.016
regulation of cellular component organization GO:0051128 368 0.016
regulation of protein transport GO:0051223 68 0.016
central nervous system development GO:0007417 311 0.016
catabolic process GO:0009056 351 0.016
gastrulation GO:0007369 2 0.016
regulation of proteolysis GO:0030162 66 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
developmental growth GO:0048589 100 0.015
positive regulation of response to external stimulus GO:0032103 51 0.015
positive regulation of isotype switching GO:0045830 1 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
positive regulation of organelle organization GO:0010638 48 0.015
response to chromate GO:0046687 3 0.015
regulation of secretion by cell GO:1903530 208 0.015
regulation of neurogenesis GO:0050767 247 0.015
response to alkaloid GO:0043279 132 0.015
regulation of system process GO:0044057 208 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
erk1 and erk2 cascade GO:0070371 48 0.014
regulation of stem cell differentiation GO:2000736 2 0.014
vitamin d biosynthetic process GO:0042368 2 0.014
regulation of response to external stimulus GO:0032101 106 0.014
immune response GO:0006955 104 0.014
neuronal action potential GO:0019228 35 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
regulation of cytokine biosynthetic process GO:0042035 3 0.014
cation homeostasis GO:0055080 195 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
regulation of protein kinase activity GO:0045859 105 0.014
positive regulation of growth GO:0045927 55 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
response to hexose GO:0009746 144 0.014
cellular response to external stimulus GO:0071496 118 0.014
regulation of transporter activity GO:0032409 50 0.014
sensory perception of bitter taste GO:0050913 4 0.014
b cell mediated immunity GO:0019724 4 0.014
sequestering of metal ion GO:0051238 9 0.014
response to testosterone GO:0033574 55 0.014
proteolysis GO:0006508 175 0.014
regulation of endopeptidase activity GO:0052548 51 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
regulation of organ growth GO:0046620 13 0.013
regulation of hormone secretion GO:0046883 106 0.013
response to glucose GO:0009749 136 0.013
bmp signaling pathway GO:0030509 4 0.013
rhythmic process GO:0048511 156 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
apoptotic process GO:0006915 381 0.013
negative regulation of developmental process GO:0051093 125 0.013
response to metal ion GO:0010038 253 0.013
establishment of protein localization GO:0045184 141 0.013
ovulation cycle process GO:0022602 50 0.013
regulation of growth GO:0040008 105 0.013
cell cycle GO:0007049 101 0.013
regulation of isotype switching GO:0045191 1 0.013
inflammatory response to antigenic stimulus GO:0002437 18 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
development of primary female sexual characteristics GO:0046545 56 0.012
signal transduction involved in regulation of gene expression GO:0023019 4 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
coronary vasculature morphogenesis GO:0060977 3 0.012
dephosphorylation GO:0016311 98 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
organ induction GO:0001759 1 0.012
fatty acid metabolic process GO:0006631 99 0.012
protein homooligomerization GO:0051260 91 0.012
peptidyl amino acid modification GO:0018193 126 0.012
vesicle mediated transport GO:0016192 181 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
neuron projection morphogenesis GO:0048812 122 0.012
isoprenoid metabolic process GO:0006720 45 0.012
regulation of inflammatory response GO:0050727 48 0.012
male gonad development GO:0008584 59 0.012
neuron differentiation GO:0030182 368 0.012
mitotic cell cycle GO:0000278 49 0.012
regulation of nervous system development GO:0051960 264 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
small molecule biosynthetic process GO:0044283 124 0.012
positive regulation of response to wounding GO:1903036 34 0.012
brain development GO:0007420 247 0.012
regulation of developmental growth GO:0048638 45 0.012
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
cellular component morphogenesis GO:0032989 155 0.012
behavior GO:0007610 205 0.012
inorganic anion transport GO:0015698 41 0.012
regulation of hormone levels GO:0010817 187 0.012
regulation of transmembrane transport GO:0034762 122 0.012
response to acid chemical GO:0001101 222 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
single organism intracellular transport GO:1902582 166 0.012
positive regulation of secretion by cell GO:1903532 128 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
gamete generation GO:0007276 124 0.011
hormone secretion GO:0046879 115 0.011
negative regulation of neuron death GO:1901215 69 0.011
anion transmembrane transport GO:0098656 77 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
negative regulation of protein processing GO:0010955 47 0.011
gliogenesis GO:0042063 93 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of cytokine secretion GO:0050707 11 0.011
positive regulation of endothelial cell migration GO:0010595 4 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
regulation of sodium ion transport GO:0002028 21 0.011
Rat
regulation of peptide transport GO:0090087 87 0.011
anterior posterior pattern specification GO:0009952 1 0.011
axon development GO:0061564 96 0.011
neuron death GO:0070997 127 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
neuron development GO:0048666 286 0.011
response to ketone GO:1901654 182 0.011
regulation of organelle organization GO:0033043 80 0.011
response to hyperoxia GO:0055093 45 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
interleukin 18 production GO:0032621 1 0.011
lymphocyte activation involved in immune response GO:0002285 3 0.011
nucleoside metabolic process GO:0009116 179 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
regulation of protein processing GO:0070613 50 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010
regulation of body fluid levels GO:0050878 90 0.010
Rat
defense response to gram negative bacterium GO:0050829 3 0.010
response to monosaccharide GO:0034284 159 0.010
regulation of peptidase activity GO:0052547 55 0.010
fat cell proliferation GO:0070341 2 0.010
response to vitamin d GO:0033280 34 0.010
regulation of neuron death GO:1901214 115 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
organic acid transport GO:0015849 116 0.010
ovulation cycle GO:0042698 67 0.010
somatic cell dna recombination GO:0016444 2 0.010
epithelial cell proliferation GO:0050673 54 0.010

Accn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.050
disease of anatomical entity DOID:7 0 0.050
connective tissue disease DOID:65 0 0.050
musculoskeletal system disease DOID:17 0 0.050
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.014
bone development disease DOID:0080006 0 0.011