Rattus norvegicus

0 known processes

Actn3

actinin alpha 3

Actn3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.332
regulation of transcription dna templated GO:0006355 374 0.214
organic substance catabolic process GO:1901575 316 0.189
regulation of rna biosynthetic process GO:2001141 381 0.176
transcription dna templated GO:0006351 377 0.161
regulation of rna metabolic process GO:0051252 391 0.159
rna biosynthetic process GO:0032774 380 0.153
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.136
tissue development GO:0009888 252 0.135
regulation of nucleic acid templated transcription GO:1903506 380 0.111
single organism catabolic process GO:0044712 283 0.107
catabolic process GO:0009056 351 0.106
positive regulation of gene expression GO:0010628 244 0.097
regulation of signal transduction GO:0009966 318 0.095
rna metabolic process GO:0016070 406 0.094
positive regulation of rna biosynthetic process GO:1902680 197 0.090
nucleoside phosphate catabolic process GO:1901292 140 0.089
central nervous system development GO:0007417 311 0.087
aromatic compound catabolic process GO:0019439 168 0.082
cellular response to oxygen containing compound GO:1901701 386 0.082
regulation of neuron differentiation GO:0045664 208 0.082
transcription from rna polymerase ii promoter GO:0006366 252 0.081
response to acid chemical GO:0001101 222 0.079
protein phosphorylation GO:0006468 345 0.078
positive regulation of transcription dna templated GO:0045893 197 0.076
nucleoside triphosphate metabolic process GO:0009141 144 0.076
cellular response to organic cyclic compound GO:0071407 202 0.075
neuron projection development GO:0031175 273 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.068
regulation of phosphorus metabolic process GO:0051174 349 0.066
regulation of protein phosphorylation GO:0001932 183 0.065
positive regulation of biosynthetic process GO:0009891 319 0.065
heterocycle catabolic process GO:0046700 167 0.063
regulation of apoptotic process GO:0042981 335 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.061
regulation of programmed cell death GO:0043067 341 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
positive regulation of nucleic acid templated transcription GO:1903508 197 0.059
regulation of cell differentiation GO:0045595 320 0.058
positive regulation of rna metabolic process GO:0051254 203 0.058
reproductive process GO:0022414 372 0.058
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
cellular nitrogen compound catabolic process GO:0044270 163 0.057
cellular component biogenesis GO:0044085 368 0.056
organonitrogen compound catabolic process GO:1901565 179 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.056
nucleoside metabolic process GO:0009116 179 0.055
neuron development GO:0048666 286 0.055
ribonucleoside triphosphate metabolic process GO:0009199 141 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.052
purine nucleotide catabolic process GO:0006195 136 0.050
regulation of catalytic activity GO:0050790 304 0.049
negative regulation of metabolic process GO:0009892 331 0.047
cellular component movement GO:0006928 248 0.046
glycosyl compound metabolic process GO:1901657 182 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.045
response to peptide hormone GO:0043434 278 0.044
cellular component assembly GO:0022607 360 0.043
negative regulation of rna biosynthetic process GO:1902679 118 0.043
negative regulation of rna metabolic process GO:0051253 123 0.043
apoptotic process GO:0006915 381 0.042
cell projection organization GO:0030030 302 0.042
dendrite morphogenesis GO:0048813 43 0.042
positive regulation of protein metabolic process GO:0051247 178 0.042
gastrulation GO:0007369 2 0.042
organic cyclic compound catabolic process GO:1901361 175 0.041
regulation of cell projection organization GO:0031344 175 0.041
purine ribonucleoside catabolic process GO:0046130 124 0.040
ribonucleoside catabolic process GO:0042454 126 0.040
regulation of neuron projection development GO:0010975 161 0.040
response to decreased oxygen levels GO:0036293 237 0.040
organelle organization GO:0006996 266 0.040
positive regulation of developmental process GO:0051094 283 0.040
nucleotide metabolic process GO:0009117 279 0.040
dendrite development GO:0016358 72 0.039
purine ribonucleotide catabolic process GO:0009154 136 0.038
positive regulation of cell communication GO:0010647 271 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.038
purine nucleotide metabolic process GO:0006163 229 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
ribose phosphate metabolic process GO:0019693 235 0.037
purine containing compound catabolic process GO:0072523 138 0.037
carbohydrate derivative catabolic process GO:1901136 147 0.037
negative regulation of programmed cell death GO:0043069 183 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
organophosphate catabolic process GO:0046434 148 0.037
cellular catabolic process GO:0044248 295 0.037
nucleobase containing compound catabolic process GO:0034655 152 0.036
purine nucleoside metabolic process GO:0042278 169 0.036
negative regulation of transcription dna templated GO:0045892 116 0.036
purine ribonucleoside metabolic process GO:0046128 168 0.036
cell motility GO:0048870 202 0.035
regulation of phosphorylation GO:0042325 248 0.035
regulation of molecular function GO:0065009 398 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.034
neuron differentiation GO:0030182 368 0.033
cellular component morphogenesis GO:0032989 155 0.033
negative regulation of cell differentiation GO:0045596 99 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
brain development GO:0007420 247 0.033
immune system process GO:0002376 204 0.032
nucleotide catabolic process GO:0009166 139 0.032
programmed cell death GO:0012501 392 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
protein complex assembly GO:0006461 263 0.032
regulation of nervous system development GO:0051960 264 0.032
response to oxygen levels GO:0070482 265 0.032
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.031
nucleoside catabolic process GO:0009164 126 0.031
single organism reproductive process GO:0044702 297 0.031
actin filament based process GO:0030029 86 0.030
response to peptide GO:1901652 292 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
negative regulation of cell death GO:0060548 229 0.030
anatomical structure formation involved in morphogenesis GO:0048646 83 0.030
cytoskeleton organization GO:0007010 111 0.029
multi organism reproductive process GO:0044703 262 0.029
regulation of cell development GO:0060284 263 0.029
digestive tract development GO:0048565 39 0.029
positive regulation of cell proliferation GO:0008284 249 0.028
positive regulation of signal transduction GO:0009967 175 0.028
cell part morphogenesis GO:0032990 123 0.028
intracellular signal transduction GO:0035556 314 0.028
response to lipopolysaccharide GO:0032496 191 0.028
protein complex biogenesis GO:0070271 263 0.028
guanosine containing compound metabolic process GO:1901068 74 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
nucleoside triphosphate catabolic process GO:0009143 123 0.028
oxoacid metabolic process GO:0043436 290 0.027
cell projection morphogenesis GO:0048858 123 0.027
purine containing compound metabolic process GO:0072521 253 0.027
anterior posterior pattern specification GO:0009952 1 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
circulatory system development GO:0072359 134 0.026
response to hypoxia GO:0001666 231 0.026
regulation of cellular component organization GO:0051128 368 0.026
negative regulation of cell development GO:0010721 82 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
head development GO:0060322 247 0.025
negative regulation of gene expression GO:0010629 199 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
muscle system process GO:0003012 115 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
formation of primary germ layer GO:0001704 1 0.025
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
ribonucleotide catabolic process GO:0009261 136 0.024
intracellular transport GO:0046907 185 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
ribonucleoside triphosphate catabolic process GO:0009203 122 0.024
signal transduction by phosphorylation GO:0023014 144 0.023
tube development GO:0035295 89 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of anatomical structure size GO:0090066 135 0.023
response to radiation GO:0009314 137 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
ribonucleotide metabolic process GO:0009259 231 0.022
regulation of protein modification process GO:0031399 194 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
regulation of protein metabolic process GO:0051246 289 0.022
regulation of catabolic process GO:0009894 113 0.022
actin cytoskeleton organization GO:0030036 73 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular response to lipid GO:0071396 201 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
mesoderm development GO:0007498 2 0.021
gamete generation GO:0007276 124 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
organophosphate metabolic process GO:0019637 370 0.020
organic acid metabolic process GO:0006082 292 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
regulation of cellular catabolic process GO:0031329 101 0.019
response to insulin GO:0032868 133 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
response to oxidative stress GO:0006979 186 0.019
cellular amine metabolic process GO:0044106 38 0.019
developmental process involved in reproduction GO:0003006 159 0.018
gtp catabolic process GO:0006184 71 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
response to cytokine GO:0034097 215 0.018
response to inorganic substance GO:0010035 377 0.018
skeletal system development GO:0001501 41 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
amine metabolic process GO:0009308 38 0.018
defense response GO:0006952 194 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
sexual reproduction GO:0019953 148 0.018
positive regulation of signaling GO:0023056 270 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
cardiovascular system development GO:0072358 134 0.017
response to light stimulus GO:0009416 52 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
guanosine containing compound catabolic process GO:1901069 71 0.017
positive regulation of molecular function GO:0044093 230 0.016
negative regulation of signaling GO:0023057 157 0.016
response to nutrient levels GO:0031667 370 0.016
response to extracellular stimulus GO:0009991 380 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
cell morphogenesis GO:0000902 142 0.016
regulation of cell proliferation GO:0042127 359 0.016
mapk cascade GO:0000165 140 0.016
muscle structure development GO:0061061 87 0.016
isoprenoid metabolic process GO:0006720 45 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
immune system development GO:0002520 41 0.015
gonad development GO:0008406 104 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
bone development GO:0060348 25 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
digestive system development GO:0055123 41 0.015
positive regulation of nervous system development GO:0051962 178 0.015
transmembrane transport GO:0055085 412 0.015
non canonical wnt signaling pathway GO:0035567 3 0.015
small gtpase mediated signal transduction GO:0007264 36 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
vasculature development GO:0001944 70 0.014
cellular response to peptide GO:1901653 133 0.014
single organism intracellular transport GO:1902582 166 0.014
gtp metabolic process GO:0046039 72 0.014
striated muscle cell differentiation GO:0051146 39 0.014
cellular response to stress GO:0033554 269 0.014
striated muscle cell development GO:0055002 26 0.014
anion transmembrane transport GO:0098656 77 0.014
neuron projection morphogenesis GO:0048812 122 0.014
embryo development GO:0009790 49 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
multi multicellular organism process GO:0044706 138 0.014
hematopoietic or lymphoid organ development GO:0048534 36 0.013
lipid metabolic process GO:0006629 283 0.013
growth GO:0040007 165 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
positive regulation of cell development GO:0010720 176 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
organ morphogenesis GO:0009887 75 0.013
multicellular organism reproduction GO:0032504 233 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
epithelium development GO:0060429 96 0.013
macromolecular complex assembly GO:0065003 273 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
motor neuron axon guidance GO:0008045 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of gtpase activity GO:0043087 57 0.013
negative regulation of nervous system development GO:0051961 79 0.012
mesoderm morphogenesis GO:0048332 1 0.012
muscle cell differentiation GO:0042692 52 0.012
mesoderm formation GO:0001707 1 0.012
male gamete generation GO:0048232 99 0.012
reproduction GO:0000003 245 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
glandular epithelial cell differentiation GO:0002067 4 0.012
response to alkaloid GO:0043279 132 0.012
erythrocyte differentiation GO:0030218 1 0.012
negative regulation of protein phosphorylation GO:0001933 44 0.012
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.012
blood circulation GO:0008015 183 0.012
cell cycle GO:0007049 101 0.011
action potential GO:0001508 54 0.011
regulation of transferase activity GO:0051338 123 0.011
localization of cell GO:0051674 202 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
positive regulation of catabolic process GO:0009896 78 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
negative regulation of developmental process GO:0051093 125 0.011
terpenoid metabolic process GO:0006721 37 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
chemosensory behavior GO:0007635 2 0.011
cellular homeostasis GO:0019725 252 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
spermatogenesis GO:0007283 99 0.011
organic acid biosynthetic process GO:0016053 83 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
response to ketone GO:1901654 182 0.011
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
cell growth GO:0016049 104 0.011
actomyosin structure organization GO:0031032 22 0.011
vasoconstriction GO:0042310 54 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
retinoid metabolic process GO:0001523 24 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
regulation of protein kinase activity GO:0045859 105 0.010

Actn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
nervous system disease DOID:863 0 0.013