Rattus norvegicus

132 known processes

Acvr1b

activin A receptor, type IB

(Aliases: Skr2)

Acvr1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.173
Fly
positive regulation of transport GO:0051050 245 0.106
regulation of cellular component biogenesis GO:0044087 86 0.085
lymphocyte activation GO:0046649 43 0.085
cell projection organization GO:0030030 302 0.082
Fly
protein phosphorylation GO:0006468 345 0.077
regulation of hormone secretion GO:0046883 106 0.075
anion transport GO:0006820 178 0.074
ribonucleotide metabolic process GO:0009259 231 0.074
regulation of phosphorus metabolic process GO:0051174 349 0.074
synaptic growth at neuromuscular junction GO:0051124 1 0.070
regulation of cell differentiation GO:0045595 320 0.069
Human Rat
reproduction GO:0000003 245 0.056
Rat Worm
regulation of multicellular organismal development GO:2000026 376 0.054
Human Rat
transcription dna templated GO:0006351 377 0.053
immune system process GO:0002376 204 0.049
Human Worm
nucleoside phosphate metabolic process GO:0006753 283 0.048
apoptotic process GO:0006915 381 0.047
Human Rat
defense response GO:0006952 194 0.046
Worm
positive regulation of secretion GO:0051047 140 0.046
homeostatic process GO:0042592 331 0.046
Human
purine containing compound metabolic process GO:0072521 253 0.045
protein complex subunit organization GO:0071822 302 0.045
Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.044
positive regulation of cell communication GO:0010647 271 0.043
single organism reproductive process GO:0044702 297 0.043
Human Rat
positive regulation of cell death GO:0010942 184 0.043
positive regulation of programmed cell death GO:0043068 157 0.043
ribonucleoside metabolic process GO:0009119 174 0.041
regulation of phosphate metabolic process GO:0019220 349 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
Rat
epithelial cell differentiation GO:0030855 71 0.040
Rat
organelle organization GO:0006996 266 0.040
negative regulation of metabolic process GO:0009892 331 0.039
Mouse Fly
regulation of programmed cell death GO:0043067 341 0.039
Rat
positive regulation of apoptotic process GO:0043065 154 0.038
regulation of cell development GO:0060284 263 0.038
regulation of protein metabolic process GO:0051246 289 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
Human Worm
protein complex assembly GO:0006461 263 0.038
Rat
neuron development GO:0048666 286 0.037
Fly
cellular component morphogenesis GO:0032989 155 0.037
Worm Fly
secretion by cell GO:0032940 248 0.037
neurological system process GO:0050877 219 0.037
regulation of signal transduction GO:0009966 318 0.036
neuron projection development GO:0031175 273 0.036
Fly
regulation of synaptic transmission GO:0050804 141 0.036
lymphocyte homeostasis GO:0002260 2 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.034
organophosphate metabolic process GO:0019637 370 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
amine metabolic process GO:0009308 38 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
rna metabolic process GO:0016070 406 0.031
heart morphogenesis GO:0003007 3 0.031
purine ribonucleoside metabolic process GO:0046128 168 0.031
negative regulation of innate immune response GO:0045824 4 0.031
regulation of transcription dna templated GO:0006355 374 0.031
multi organism reproductive process GO:0044703 262 0.030
Human Rat
muscle system process GO:0003012 115 0.030
leukocyte activation GO:0045321 76 0.029
regulation of neuron differentiation GO:0045664 208 0.029
cell cell signaling GO:0007267 335 0.029
positive regulation of developmental process GO:0051094 283 0.028
Human Rat Worm
nucleic acid templated transcription GO:0097659 379 0.028
positive regulation of protein modification process GO:0031401 142 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
cyclic nucleotide metabolic process GO:0009187 80 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
Human
mesoderm development GO:0007498 2 0.027
Zebrafish
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
behavior GO:0007610 205 0.027
regulation of nervous system development GO:0051960 264 0.027
nucleotide metabolic process GO:0009117 279 0.026
regulation of molecular function GO:0065009 398 0.026
multicellular organism growth GO:0035264 1 0.026
Worm
cytoskeleton organization GO:0007010 111 0.025
cellular amine metabolic process GO:0044106 38 0.025
nucleoside catabolic process GO:0009164 126 0.025
sensory perception GO:0007600 101 0.025
positive regulation of signal transduction GO:0009967 175 0.024
macromolecule localization GO:0033036 252 0.024
Worm
cell type specific apoptotic process GO:0097285 134 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
synapse organization GO:0050808 46 0.023
positive regulation of molecular function GO:0044093 230 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
regulation of neuron projection development GO:0010975 161 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
intracellular transport GO:0046907 185 0.023
regulation of neurogenesis GO:0050767 247 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
gastrulation GO:0007369 2 0.023
Zebrafish
organ regeneration GO:0031100 101 0.022
Rat
cellular component assembly GO:0022607 360 0.022
Rat
head development GO:0060322 247 0.022
Rat Fly
insulin secretion GO:0030073 69 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cell morphogenesis GO:0000902 142 0.022
Worm Fly
growth GO:0040007 165 0.022
Human Zebrafish Rat Worm
regulation of heart rate GO:0002027 16 0.022
epidermis development GO:0008544 11 0.022
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.022
immune response GO:0006955 104 0.022
Worm
response to alkaloid GO:0043279 132 0.022
regulation of neuron apoptotic process GO:0043523 83 0.021
cyclic purine nucleotide metabolic process GO:0052652 62 0.021
cellular ketone metabolic process GO:0042180 51 0.021
regulation of cell projection organization GO:0031344 175 0.021
synaptic transmission glutamatergic GO:0035249 33 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
ribonucleoside triphosphate catabolic process GO:0009203 122 0.020
peptide hormone secretion GO:0030072 84 0.020
cellular component biogenesis GO:0044085 368 0.020
Rat
cation transport GO:0006812 382 0.020
cellular cation homeostasis GO:0030003 180 0.020
response to peptide hormone GO:0043434 278 0.020
synapse assembly GO:0007416 29 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
cation homeostasis GO:0055080 195 0.019
divalent inorganic cation transport GO:0072511 134 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
t helper 1 type immune response GO:0042088 1 0.019
hormone transport GO:0009914 121 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
blood circulation GO:0008015 183 0.019
salivary gland morphogenesis GO:0007435 1 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
positive regulation of ion transport GO:0043270 94 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.018
regulation of cytoskeleton organization GO:0051493 49 0.018
ras protein signal transduction GO:0007265 29 0.018
developmental process involved in reproduction GO:0003006 159 0.018
protein complex biogenesis GO:0070271 263 0.018
Rat
epithelium development GO:0060429 96 0.018
Mouse Rat
neuromuscular synaptic transmission GO:0007274 2 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
neuron death GO:0070997 127 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
programmed cell death GO:0012501 392 0.018
Human Rat
reproductive process GO:0022414 372 0.018
regulation of neuron death GO:1901214 115 0.017
immune system development GO:0002520 41 0.017
Human
single organism organelle organization GO:1902589 180 0.017
synaptic transmission GO:0007268 235 0.017
regulation of peptide hormone secretion GO:0090276 80 0.017
positive regulation of immune system process GO:0002684 90 0.017
Human
gliogenesis GO:0042063 93 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
negative regulation of cell communication GO:0010648 158 0.017
dephosphorylation GO:0016311 98 0.017
hormone secretion GO:0046879 115 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
Rat
regulation of blood circulation GO:1903522 110 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
central nervous system development GO:0007417 311 0.017
establishment of protein localization GO:0045184 141 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
metal ion transport GO:0030001 289 0.016
macromolecular complex assembly GO:0065003 273 0.016
Rat
single organism intracellular transport GO:1902582 166 0.016
folic acid containing compound metabolic process GO:0006760 10 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of cellular component organization GO:0051128 368 0.016
Human Worm
proteolysis GO:0006508 175 0.016
regulation of rna metabolic process GO:0051252 391 0.016
nucleoside metabolic process GO:0009116 179 0.016
signal release GO:0023061 145 0.016
dendrite development GO:0016358 72 0.016
regulation of organelle organization GO:0033043 80 0.016
gtp metabolic process GO:0046039 72 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
immune effector process GO:0002252 53 0.016
actin filament based process GO:0030029 86 0.016
regulation of immune system process GO:0002682 123 0.016
Human
regulation of cell proliferation GO:0042127 359 0.016
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of apoptotic process GO:0042981 335 0.016
Rat
positive regulation of camp biosynthetic process GO:0030819 28 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
regulation of phosphorylation GO:0042325 248 0.015
cellular response to stress GO:0033554 269 0.015
response to extracellular stimulus GO:0009991 380 0.015
Rat
intracellular signal transduction GO:0035556 314 0.015
startle response GO:0001964 2 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
oxoacid metabolic process GO:0043436 290 0.015
peptide secretion GO:0002790 86 0.015
sensory perception of pain GO:0019233 73 0.015
gamete generation GO:0007276 124 0.015
regulation of synapse assembly GO:0051963 15 0.015
peptidyl amino acid modification GO:0018193 126 0.015
Human Mouse
cellular homeostasis GO:0019725 252 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
response to glucose GO:0009749 136 0.014
Rat
negative regulation of neuron apoptotic process GO:0043524 45 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
regulation of dendrite development GO:0050773 59 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of system process GO:0044057 208 0.014
neuromuscular process GO:0050905 2 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
response to amine GO:0014075 46 0.014
regulation of secretion by cell GO:1903530 208 0.014
metal ion homeostasis GO:0055065 186 0.014
regulation of acute inflammatory response GO:0002673 23 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
circulatory system development GO:0072359 134 0.014
Rat
t cell homeostasis GO:0043029 2 0.014
protein autophosphorylation GO:0046777 66 0.014
Human Rat
regulation of insulin secretion GO:0050796 65 0.014
neuron projection morphogenesis GO:0048812 122 0.014
Fly
organic substance catabolic process GO:1901575 316 0.014
Worm
cell projection morphogenesis GO:0048858 123 0.014
Fly
secretion GO:0046903 307 0.013
hematopoietic or lymphoid organ development GO:0048534 36 0.013
Human
purine containing compound biosynthetic process GO:0072522 85 0.013
regulation of protein modification process GO:0031399 194 0.013
cellular chemical homeostasis GO:0055082 247 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
neuron apoptotic process GO:0051402 88 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
regulation of kinase activity GO:0043549 117 0.013
male gamete generation GO:0048232 99 0.013
sexual reproduction GO:0019953 148 0.013
regulation of hormone levels GO:0010817 187 0.013
response to nutrient levels GO:0031667 370 0.013
Rat
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
response to cytokine GO:0034097 215 0.013
cell part morphogenesis GO:0032990 123 0.013
Fly
response to growth factor GO:0070848 189 0.013
Rat
regulation of camp metabolic process GO:0030814 43 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
Fly
glycosyl compound metabolic process GO:1901657 182 0.013
positive regulation of digestive system process GO:0060456 8 0.013
regulation of cellular catabolic process GO:0031329 101 0.012
Fly
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
Rat
biological adhesion GO:0022610 110 0.012
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of defense response GO:0031347 68 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
regulation of transferase activity GO:0051338 123 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
cellular response to lipid GO:0071396 201 0.012
Rat
nucleotide catabolic process GO:0009166 139 0.012
negative regulation of signaling GO:0023057 157 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
tongue morphogenesis GO:0043587 3 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
sensory perception of light stimulus GO:0050953 3 0.012
axon development GO:0061564 96 0.012
Fly
regulation of cell morphogenesis GO:0022604 77 0.012
Worm
multicellular organism reproduction GO:0032504 233 0.012
Rat
cognition GO:0050890 92 0.012
negative regulation of vascular permeability GO:0043116 3 0.012
ion transmembrane transport GO:0034220 365 0.012
sex differentiation GO:0007548 113 0.011
response to organophosphorus GO:0046683 102 0.011
intracellular protein transport GO:0006886 79 0.011
spermatogenesis GO:0007283 99 0.011
cellular component movement GO:0006928 248 0.011
Human Fly
ion homeostasis GO:0050801 212 0.011
lipid transport GO:0006869 61 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
negative regulation of synaptic transmission GO:0050805 29 0.011
regulation of inflammatory response GO:0050727 48 0.011
salivary gland development GO:0007431 3 0.011
anterior posterior pattern specification GO:0009952 1 0.011
glial cell differentiation GO:0010001 65 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
regulation of muscle contraction GO:0006937 53 0.011
glucose metabolic process GO:0006006 52 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
response to ethanol GO:0045471 162 0.011
cell cycle checkpoint GO:0000075 2 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
sequestering of calcium ion GO:0051208 8 0.011
single organism behavior GO:0044708 130 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
organic acid metabolic process GO:0006082 292 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
heterocycle catabolic process GO:0046700 167 0.011
regulation of catalytic activity GO:0050790 304 0.011
cellular protein complex assembly GO:0043623 44 0.011
Rat
positive regulation of defense response GO:0031349 37 0.011
formation of primary germ layer GO:0001704 1 0.011
Zebrafish
tolerance induction dependent upon immune response GO:0002461 2 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cell cycle GO:0007049 101 0.011
Human Fly
cellular response to peptide GO:1901653 133 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
developmental growth GO:0048589 100 0.010
Zebrafish Rat Worm
cell activation GO:0001775 97 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
visual perception GO:0007601 3 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
chromosome segregation GO:0007059 2 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
leukocyte differentiation GO:0002521 30 0.010
cell growth GO:0016049 104 0.010
Human
regulation of hydrolase activity GO:0051336 143 0.010
regulation of leukocyte activation GO:0002694 45 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
response to bacterium GO:0009617 200 0.010
sequestering of metal ion GO:0051238 9 0.010
chemosensory behavior GO:0007635 2 0.010
regulation of cell activation GO:0050865 50 0.010

Acvr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036
central nervous system disease DOID:331 0 0.014
connective tissue disease DOID:65 0 0.013
musculoskeletal system disease DOID:17 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010