Rattus norvegicus

2 known processes

Acy1

aminoacylase 1

(Aliases: Acy1b,Acy1a)

Acy1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.638
organic acid metabolic process GO:0006082 292 0.571
oxoacid metabolic process GO:0043436 290 0.559
catabolic process GO:0009056 351 0.290
organic substance catabolic process GO:1901575 316 0.198
monocarboxylic acid metabolic process GO:0032787 152 0.196
cellular amino acid metabolic process GO:0006520 107 0.195
cellular amino acid biosynthetic process GO:0008652 32 0.178
response to nutrient levels GO:0031667 370 0.177
cellular amino acid catabolic process GO:0009063 21 0.176
alpha amino acid catabolic process GO:1901606 20 0.163
single organism catabolic process GO:0044712 283 0.151
response to nutrient GO:0007584 248 0.146
organonitrogen compound biosynthetic process GO:1901566 167 0.134
single organism biosynthetic process GO:0044711 342 0.123
response to extracellular stimulus GO:0009991 380 0.120
alpha amino acid metabolic process GO:1901605 71 0.119
alpha amino acid biosynthetic process GO:1901607 23 0.107
cellular catabolic process GO:0044248 295 0.099
carboxylic acid catabolic process GO:0046395 49 0.095
cation transport GO:0006812 382 0.094
metal ion transport GO:0030001 289 0.088
small molecule biosynthetic process GO:0044283 124 0.087
lipid biosynthetic process GO:0008610 128 0.072
negative regulation of metabolic process GO:0009892 331 0.068
response to peptide GO:1901652 292 0.066
rna metabolic process GO:0016070 406 0.064
single organism reproductive process GO:0044702 297 0.061
cofactor metabolic process GO:0051186 95 0.058
reproduction GO:0000003 245 0.057
transmembrane transport GO:0055085 412 0.056
carboxylic acid biosynthetic process GO:0046394 83 0.054
coenzyme metabolic process GO:0006732 86 0.054
cellular lipid metabolic process GO:0044255 208 0.053
reproductive process GO:0022414 372 0.053
hair cycle process GO:0022405 2 0.052
cellular modified amino acid biosynthetic process GO:0042398 18 0.051
liver development GO:0001889 90 0.049
toxin catabolic process GO:0009407 1 0.048
organic hydroxy compound metabolic process GO:1901615 115 0.047
secondary metabolite catabolic process GO:0090487 1 0.045
ion homeostasis GO:0050801 212 0.045
response to hypoxia GO:0001666 231 0.045
aging GO:0007568 241 0.044
response to vitamin GO:0033273 131 0.043
oxidation reduction process GO:0055114 304 0.043
organonitrogen compound catabolic process GO:1901565 179 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
gland development GO:0048732 155 0.041
response to corticosteroid GO:0031960 235 0.041
regulation of cell differentiation GO:0045595 320 0.041
response to decreased oxygen levels GO:0036293 237 0.040
transcription dna templated GO:0006351 377 0.040
response to glucocorticoid GO:0051384 223 0.040
sexual reproduction GO:0019953 148 0.038
regulation of hormone levels GO:0010817 187 0.038
response to molecule of bacterial origin GO:0002237 194 0.037
organic acid biosynthetic process GO:0016053 83 0.037
regulation of neurogenesis GO:0050767 247 0.037
axon development GO:0061564 96 0.036
response to bacterium GO:0009617 200 0.036
lipid metabolic process GO:0006629 283 0.036
immune system process GO:0002376 204 0.036
response to inorganic substance GO:0010035 377 0.035
hair follicle development GO:0001942 2 0.035
positive regulation of neurogenesis GO:0050769 165 0.035
neurological system process GO:0050877 219 0.035
nucleic acid templated transcription GO:0097659 379 0.035
multicellular organism reproduction GO:0032504 233 0.034
macromolecular complex assembly GO:0065003 273 0.034
regulation of cell development GO:0060284 263 0.033
regulation of response to external stimulus GO:0032101 106 0.032
cellular modified amino acid metabolic process GO:0006575 61 0.032
rna biosynthetic process GO:0032774 380 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
positive regulation of nervous system development GO:0051962 178 0.032
monovalent inorganic cation transport GO:0015672 172 0.032
regulation of molecular function GO:0065009 398 0.032
response to estrogen GO:0043627 232 0.031
regulation of immune system process GO:0002682 123 0.031
regulation of nervous system development GO:0051960 264 0.031
cellular component assembly GO:0022607 360 0.031
regulation of signal transduction GO:0009966 318 0.031
neuron development GO:0048666 286 0.031
response to ketone GO:1901654 182 0.031
programmed cell death GO:0012501 392 0.031
protein phosphorylation GO:0006468 345 0.030
response to biotic stimulus GO:0009607 226 0.030
response to other organism GO:0051707 220 0.030
cellular ketone metabolic process GO:0042180 51 0.030
defense response GO:0006952 194 0.030
positive regulation of cell differentiation GO:0045597 217 0.029
response to peptide hormone GO:0043434 278 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
aromatic amino acid family metabolic process GO:0009072 9 0.029
regulation of ion transport GO:0043269 245 0.029
ion transmembrane transport GO:0034220 365 0.029
immune response GO:0006955 104 0.028
cellular response to stress GO:0033554 269 0.028
protein complex biogenesis GO:0070271 263 0.028
regulation of neuron differentiation GO:0045664 208 0.028
organelle organization GO:0006996 266 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
blood circulation GO:0008015 183 0.028
proteolysis GO:0006508 175 0.027
inorganic ion transmembrane transport GO:0098660 229 0.027
inflammatory response GO:0006954 150 0.027
cellular amine metabolic process GO:0044106 38 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
central nervous system development GO:0007417 311 0.026
gamete generation GO:0007276 124 0.026
localization of cell GO:0051674 202 0.025
nicotinamide nucleotide metabolic process GO:0046496 28 0.025
cell migration GO:0016477 197 0.025
cell motility GO:0048870 202 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
cell projection organization GO:0030030 302 0.025
nitrogen compound transport GO:0071705 229 0.025
response to oxygen levels GO:0070482 265 0.025
head development GO:0060322 247 0.025
response to temperature stimulus GO:0009266 94 0.025
chemical homeostasis GO:0048878 292 0.025
brain development GO:0007420 247 0.024
regulation of cellular response to stress GO:0080135 49 0.024
neuron differentiation GO:0030182 368 0.024
regulation of cellular component movement GO:0051270 150 0.024
response to lipopolysaccharide GO:0032496 191 0.024
regulation of catabolic process GO:0009894 113 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
organic acid catabolic process GO:0016054 49 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
neuron projection development GO:0031175 273 0.023
response to external biotic stimulus GO:0043207 221 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
pteridine containing compound metabolic process GO:0042558 14 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.022
cation homeostasis GO:0055080 195 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
cofactor biosynthetic process GO:0051188 28 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
positive regulation of locomotion GO:0040017 102 0.022
ncrna processing GO:0034470 3 0.022
circulatory system process GO:0003013 183 0.022
cellular homeostasis GO:0019725 252 0.022
amine metabolic process GO:0009308 38 0.022
cellular component movement GO:0006928 248 0.022
regulation of cellular component organization GO:0051128 368 0.021
regulation of response to stress GO:0080134 126 0.021
organophosphate metabolic process GO:0019637 370 0.021
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.021
pyruvate metabolic process GO:0006090 27 0.021
response to vitamin e GO:0033197 24 0.021
cell projection morphogenesis GO:0048858 123 0.021
positive regulation of cell development GO:0010720 176 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
locomotion GO:0040011 237 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
regulation of cell projection organization GO:0031344 175 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
metal ion homeostasis GO:0055065 186 0.020
cation transmembrane transport GO:0098655 263 0.019
regulation of apoptotic process GO:0042981 335 0.019
multi organism reproductive process GO:0044703 262 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of developmental process GO:0051094 283 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
generation of precursor metabolites and energy GO:0006091 62 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
cellular metal ion homeostasis GO:0006875 172 0.018
response to metal ion GO:0010038 253 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
regulation of rna metabolic process GO:0051252 391 0.018
nucleotide metabolic process GO:0009117 279 0.018
regulation of catalytic activity GO:0050790 304 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
amide biosynthetic process GO:0043604 10 0.018
protein oligomerization GO:0051259 191 0.018
cellular cation homeostasis GO:0030003 180 0.018
cellular ion homeostasis GO:0006873 184 0.018
positive regulation of molecular function GO:0044093 230 0.018
cellular response to lipid GO:0071396 201 0.018
homeostatic process GO:0042592 331 0.017
regulation of transcription dna templated GO:0006355 374 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of neuron projection development GO:0010975 161 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
response to amine GO:0014075 46 0.017
spermatogenesis GO:0007283 99 0.017
response to mechanical stimulus GO:0009612 134 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
protein complex subunit organization GO:0071822 302 0.017
protein complex assembly GO:0006461 263 0.017
organic acid transport GO:0015849 116 0.017
secretion GO:0046903 307 0.017
cellular component morphogenesis GO:0032989 155 0.017
apoptotic process GO:0006915 381 0.017
sulfur amino acid biosynthetic process GO:0000097 5 0.017
cellular component biogenesis GO:0044085 368 0.017
regulation of metal ion transport GO:0010959 118 0.017
small molecule catabolic process GO:0044282 59 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
hair cycle GO:0042633 3 0.016
negative regulation of gene expression GO:0010629 199 0.016
fatty acid metabolic process GO:0006631 99 0.016
tissue development GO:0009888 252 0.016
acute inflammatory response GO:0002526 58 0.016
response to insulin GO:0032868 133 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
response to estradiol GO:0032355 164 0.016
lipid catabolic process GO:0016042 46 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
response to toxic substance GO:0009636 133 0.016
regulation of glucose transport GO:0010827 18 0.016
negative regulation of cell death GO:0060548 229 0.016
macromolecule localization GO:0033036 252 0.015
regulation of cell proliferation GO:0042127 359 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regulation of cell motility GO:2000145 131 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
axis specification GO:0009798 4 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
hexose transport GO:0008645 29 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
cellular chemical homeostasis GO:0055082 247 0.015
potassium ion transport GO:0006813 97 0.015
positive regulation of smooth muscle cell migration GO:0014911 27 0.015
carbohydrate catabolic process GO:0016052 40 0.015
behavior GO:0007610 205 0.015
carboxylic acid transport GO:0046942 115 0.015
cellular response to peptide GO:1901653 133 0.014
hepaticobiliary system development GO:0061008 90 0.014
regulation of blood pressure GO:0008217 83 0.014
regulation of programmed cell death GO:0043067 341 0.014
toxin metabolic process GO:0009404 9 0.014
regulation of phosphorylation GO:0042325 248 0.014
response to acid chemical GO:0001101 222 0.014
cellular response to alcohol GO:0097306 87 0.014
protein homooligomerization GO:0051260 91 0.014
fatty acid oxidation GO:0019395 29 0.014
regulation of locomotion GO:0040012 148 0.014
amide transport GO:0042886 105 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cellular modified amino acid catabolic process GO:0042219 1 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
positive regulation of cell motility GO:2000147 97 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
regulation of immune response GO:0050776 55 0.014
calcium ion homeostasis GO:0055074 162 0.013
circadian rhythm GO:0007623 88 0.013
male gamete generation GO:0048232 99 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of carbohydrate catabolic process GO:0043470 14 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
response to wounding GO:0009611 254 0.013
epithelium development GO:0060429 96 0.013
gastrulation GO:0007369 2 0.013
regulation of system process GO:0044057 208 0.013
single organism carbohydrate catabolic process GO:0044724 40 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular lipid catabolic process GO:0044242 37 0.013
regulation of response to wounding GO:1903034 69 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
embryonic pattern specification GO:0009880 1 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of cell migration GO:0030334 128 0.013
anterior posterior pattern specification GO:0009952 1 0.013
neurotransmitter biosynthetic process GO:0042136 2 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
macroautophagy GO:0016236 4 0.013
anion transmembrane transport GO:0098656 77 0.013
cell morphogenesis GO:0000902 142 0.012
negative regulation of signaling GO:0023057 157 0.012
heterocycle catabolic process GO:0046700 167 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
positive regulation of signal transduction GO:0009967 175 0.012
eye morphogenesis GO:0048592 4 0.012
phospholipid metabolic process GO:0006644 61 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of protein modification process GO:0031399 194 0.012
protein tetramerization GO:0051262 38 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
anion transport GO:0006820 178 0.012
regulation of potassium ion transport GO:0043266 29 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
rhythmic process GO:0048511 156 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
positive regulation of cell migration GO:0030335 96 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
response to axon injury GO:0048678 59 0.011
positive regulation of immune system process GO:0002684 90 0.011
positive regulation of transport GO:0051050 245 0.011
positive regulation of protein modification process GO:0031401 142 0.011
intracellular transport GO:0046907 185 0.011
aromatic amino acid family catabolic process GO:0009074 7 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of gene expression GO:0010628 244 0.011
muscle system process GO:0003012 115 0.011
regulation of inflammatory response GO:0050727 48 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
positive regulation of inflammatory response GO:0050729 24 0.011
regulation of glycolytic process GO:0006110 7 0.011
positive regulation of cell communication GO:0010647 271 0.011
aromatic compound catabolic process GO:0019439 168 0.011
response to radiation GO:0009314 137 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
coenzyme biosynthetic process GO:0009108 22 0.011
regulation of growth GO:0040008 105 0.011
positive regulation of ion transport GO:0043270 94 0.011
nucleoside metabolic process GO:0009116 179 0.011
feeding behavior GO:0007631 53 0.011
glycolytic process GO:0006096 17 0.010
neuron projection morphogenesis GO:0048812 122 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
positive regulation of immune response GO:0050778 42 0.010
hormone metabolic process GO:0042445 69 0.010
positive regulation of transferase activity GO:0051347 81 0.010
rna localization GO:0006403 4 0.010
divalent metal ion transport GO:0070838 132 0.010
response to carbohydrate GO:0009743 183 0.010
positive regulation of defense response GO:0031349 37 0.010
salivary gland development GO:0007431 3 0.010
positive regulation of catabolic process GO:0009896 78 0.010
lipid modification GO:0030258 52 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
positive regulation of kinase activity GO:0033674 77 0.010

Acy1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.010