|
|
tissue development
|
GO:0009888 |
252 |
0.506
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.446
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.394
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.354
|
|
|
|
transforming growth factor beta receptor complex assembly
|
GO:0007181 |
2 |
0.344
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.343
|
|
|
|
hemidesmosome assembly
|
GO:0031581 |
1 |
0.307
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.305
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.303
|
|
|
|
protein processing
|
GO:0016485 |
68 |
0.301
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
3 |
0.290
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.286
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.274
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.274
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.273
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.224
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.219
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
130 |
0.216
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
19 |
0.213
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.205
|
Mouse |
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.205
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
3 |
0.187
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.183
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.180
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.179
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.171
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.171
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.166
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.166
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.165
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.163
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.162
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.161
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.161
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.157
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.156
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.152
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.151
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.149
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.148
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
9 |
0.146
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
123 |
0.145
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.145
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.142
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.142
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.142
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.140
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.138
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.138
|
|
|
|
positive regulation of retinal cell programmed cell death
|
GO:0046670 |
1 |
0.137
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.136
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.135
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.135
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.133
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.133
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
13 |
0.132
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.131
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
34 |
0.129
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.126
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.125
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.125
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
83 |
0.125
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.124
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.124
|
|
|
|
regulation of protein transport
|
GO:0051223 |
68 |
0.124
|
|
|
|
regulation of behavior
|
GO:0050795 |
61 |
0.121
|
Human |
|
|
regulation of retinal cell programmed cell death
|
GO:0046668 |
1 |
0.119
|
|
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.119
|
|
|
|
endocytosis
|
GO:0006897 |
84 |
0.117
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.117
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.116
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.114
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.113
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
3 |
0.113
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.112
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.111
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.111
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.110
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.109
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.109
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.109
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.105
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.103
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.102
|
|
|
|
positive regulation of dendritic spine morphogenesis
|
GO:0061003 |
3 |
0.102
|
|
|
|
learning
|
GO:0007612 |
33 |
0.100
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.098
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.098
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.097
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.097
|
|
|
|
protein o linked glycosylation
|
GO:0006493 |
2 |
0.097
|
|
|
|
protein maturation
|
GO:0051604 |
68 |
0.095
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.095
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.094
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.093
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.093
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.089
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
42 |
0.088
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
3 |
0.087
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.087
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.087
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.086
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.086
|
Human |
|
|
divalent metal ion transport
|
GO:0070838 |
132 |
0.086
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.085
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.085
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.085
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
118 |
0.084
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.082
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.082
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.082
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.081
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.081
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.081
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.081
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
231 |
0.080
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.078
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.078
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.078
|
|
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.078
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.078
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.077
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
18 |
0.076
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
3 |
0.076
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
89 |
0.075
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
2 |
0.074
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.074
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.074
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
2 |
0.073
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.072
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.072
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.071
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.071
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.071
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.070
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.070
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
25 |
0.070
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.069
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.069
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
140 |
0.069
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.068
|
Human |
|
|
head development
|
GO:0060322 |
247 |
0.068
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.068
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.068
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
31 |
0.068
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.068
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.067
|
|
|
|
negative regulation of defecation
|
GO:2000293 |
1 |
0.067
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
81 |
0.067
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
126 |
0.066
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.066
|
Fly |
|
|
reproductive process
|
GO:0022414 |
372 |
0.065
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.065
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
124 |
0.064
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
168 |
0.064
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
33 |
0.064
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.064
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.063
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
15 |
0.063
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.063
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.062
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.062
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.061
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.060
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.060
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.060
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
21 |
0.060
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.059
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.059
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.058
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.058
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
50 |
0.058
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.058
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
42 |
0.057
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.057
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.057
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.057
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.056
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.055
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.055
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
122 |
0.055
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.055
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
44 |
0.055
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.055
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.054
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.054
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.054
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.054
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.053
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.053
|
|
|
|
heart process
|
GO:0003015 |
57 |
0.053
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.053
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.052
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.052
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
122 |
0.052
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
7 |
0.052
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.052
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.051
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
32 |
0.051
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.051
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.051
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.050
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.050
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.050
|
|
|
|
regulation of neuron death
|
GO:1901214 |
115 |
0.050
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.050
|
|
|
|
regulation of defense response
|
GO:0031347 |
68 |
0.048
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.048
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.047
|
|
|
|
response to insulin
|
GO:0032868 |
133 |
0.047
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.047
|
|
|
|
neuron fate commitment
|
GO:0048663 |
4 |
0.047
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
126 |
0.047
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.047
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
47 |
0.047
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
36 |
0.047
|
Human |
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.046
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
136 |
0.046
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.046
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.046
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.045
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
9 |
0.044
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
8 |
0.044
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.044
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.044
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.043
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.043
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.043
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
179 |
0.042
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.042
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.042
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
8 |
0.042
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.042
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
18 |
0.042
|
|
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.042
|
|
|
|
learning or memory
|
GO:0007611 |
90 |
0.042
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.042
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.042
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.042
|
|
|
|
response to oxygen levels
|
GO:0070482 |
265 |
0.041
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.041
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.041
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.041
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.041
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.041
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.041
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
91 |
0.041
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.041
|
|
|
|
male mating behavior
|
GO:0060179 |
3 |
0.041
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
21 |
0.040
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.040
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.040
|
|
|
|
aging
|
GO:0007568 |
241 |
0.040
|
|
|
|
regulation of protein processing
|
GO:0070613 |
50 |
0.040
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.040
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.040
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.039
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.039
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
69 |
0.039
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.038
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
31 |
0.038
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.038
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
2 |
0.038
|
|
|
|
follicle stimulating hormone signaling pathway
|
GO:0042699 |
5 |
0.038
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.038
|
|
|
|
regulation of skeletal muscle tissue regeneration
|
GO:0043416 |
2 |
0.038
|
|
|
|
negative regulation of calcium ion import
|
GO:0090281 |
2 |
0.038
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
28 |
0.038
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.037
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.037
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.037
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
36 |
0.037
|
|
|
|
spindle organization
|
GO:0007051 |
2 |
0.037
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.036
|
|
|
|
limbic system development
|
GO:0021761 |
38 |
0.036
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.036
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.036
|
|
|
|
tube formation
|
GO:0035148 |
3 |
0.036
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.036
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.035
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.035
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
4 |
0.035
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
36 |
0.035
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.035
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.035
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.035
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.034
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.034
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.034
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
4 |
0.034
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.034
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
56 |
0.034
|
|
|
|
response to glucose
|
GO:0009749 |
136 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.033
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
14 |
0.033
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.033
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
27 |
0.033
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
90 |
0.033
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
71 |
0.033
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
3 |
0.032
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.032
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.032
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.032
|
|
|
|
positive regulation of tolerance induction
|
GO:0002645 |
1 |
0.032
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
152 |
0.032
|
|
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.032
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
4 |
0.032
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
28 |
0.032
|
|
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.032
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.031
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.031
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
25 |
0.031
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.031
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
38 |
0.031
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
43 |
0.031
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.031
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.031
|
Human |
|
|
sex differentiation
|
GO:0007548 |
113 |
0.031
|
|
|
|
growth
|
GO:0040007 |
165 |
0.031
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
1 |
0.031
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.030
|
|
|
|
vasculogenesis
|
GO:0001570 |
3 |
0.030
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.030
|
|
|
|
homeostatic process
|
GO:0042592 |
331 |
0.030
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
23 |
0.030
|
|
|
|
female sex differentiation
|
GO:0046660 |
59 |
0.030
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.030
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
85 |
0.030
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.030
|
|
|
|
cellular response to glucagon stimulus
|
GO:0071377 |
7 |
0.030
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.030
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.029
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
34 |
0.029
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
33 |
0.029
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.029
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.029
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.029
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.029
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.029
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.029
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
21 |
0.029
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
144 |
0.028
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.028
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.028
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.028
|
|
|
|
lung development
|
GO:0030324 |
43 |
0.028
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.028
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.028
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
65 |
0.028
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.028
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.028
|
|
|
|
positive regulation of skeletal muscle tissue regeneration
|
GO:0043415 |
1 |
0.028
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.028
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.028
|
|
|
|
regulation of glycoprotein metabolic process
|
GO:1903018 |
6 |
0.028
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.028
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.027
|
|
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.027
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
48 |
0.027
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.027
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
191 |
0.026
|
|
|
|
mitochondrion organization
|
GO:0007005 |
35 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
56 |
0.026
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.026
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.026
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.026
|
|
|
|
neuron projection development
|
GO:0031175 |
273 |
0.026
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.026
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.026
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
47 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.025
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.025
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.025
|
|
|
|
neuron death
|
GO:0070997 |
127 |
0.025
|
|
|
|
cytokinetic process
|
GO:0032506 |
1 |
0.025
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.025
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.025
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.025
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
47 |
0.025
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.025
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.025
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.025
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.025
|
|
|
|
atp catabolic process
|
GO:0006200 |
54 |
0.024
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.024
|
|
|
|
neuron development
|
GO:0048666 |
286 |
0.024
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.024
|
|
|
|
immune system process
|
GO:0002376 |
204 |
0.024
|
Human |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.024
|
|
|
|
response to amino acid
|
GO:0043200 |
75 |
0.024
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.024
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
55 |
0.024
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.024
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.024
|
Human |
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.024
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
11 |
0.024
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.024
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.024
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.024
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
44 |
0.024
|
|
|
|
single organism behavior
|
GO:0044708 |
130 |
0.024
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.023
|
|
|
|
positive regulation of adenylate cyclase activity
|
GO:0045762 |
12 |
0.023
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.023
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.023
|
|
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.023
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
58 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
81 |
0.023
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.023
|
|
|
|
response to cobalt ion
|
GO:0032025 |
12 |
0.023
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
81 |
0.023
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
65 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.022
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
85 |
0.022
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
3 |
0.022
|
|
|
|
chemosensory behavior
|
GO:0007635 |
2 |
0.022
|
|
|
|
cell junction assembly
|
GO:0034329 |
18 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.022
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.022
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.022
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.022
|
|
|
|
response to anoxia
|
GO:0034059 |
4 |
0.022
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
2 |
0.021
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.021
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.021
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.021
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.021
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.021
|
|
|
|
negative regulation of luteinizing hormone secretion
|
GO:0033685 |
4 |
0.021
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.021
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.021
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.021
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.021
|
|
|
|
negative regulation of follicle stimulating hormone secretion
|
GO:0046882 |
3 |
0.021
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.021
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.021
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.021
|
|
|
|
memory
|
GO:0007613 |
54 |
0.021
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.021
|
|
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.020
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.020
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.020
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.020
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.020
|
|
|
|
reproductive behavior
|
GO:0019098 |
10 |
0.020
|
|
|
|
visual learning
|
GO:0008542 |
8 |
0.020
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
52 |
0.020
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.020
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
3 |
0.020
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.020
|
Human |
|
|
sensory organ development
|
GO:0007423 |
74 |
0.020
|
|
|
|
camera type eye development
|
GO:0043010 |
48 |
0.020
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
39 |
0.020
|
|
|
|
response to fatty acid
|
GO:0070542 |
65 |
0.020
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
24 |
0.020
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.020
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.020
|
|
|
|
hormone metabolic process
|
GO:0042445 |
69 |
0.020
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
39 |
0.020
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
41 |
0.020
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.020
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
5 |
0.020
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.019
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
41 |
0.019
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.019
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.019
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
1 |
0.019
|
|
|
|
acute inflammatory response to non antigenic stimulus
|
GO:0002525 |
2 |
0.019
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.019
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.019
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.019
|
|
|
|
cell adhesion
|
GO:0007155 |
110 |
0.019
|
Human |
|
|
retinal cell programmed cell death
|
GO:0046666 |
1 |
0.019
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.019
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
63 |
0.019
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
20 |
0.019
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
37 |
0.019
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.018
|
|
|
|
female genitalia development
|
GO:0030540 |
3 |
0.018
|
|
|
|
bone remodeling
|
GO:0046849 |
23 |
0.018
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.018
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.018
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.018
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
32 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
61 |
0.018
|
|
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.018
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
20 |
0.018
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.018
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.018
|
|
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.017
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.017
|
|
|
|
positive regulation of growth
|
GO:0045927 |
55 |
0.017
|
Human |
