Rattus norvegicus

0 known processes

Adam5

a disintegrin and metallopeptidase domain 5

(Aliases: MGC108772,tMDCII)

Adam5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.206
regulation of multicellular organismal development GO:2000026 376 0.196
regulation of secretion by cell GO:1903530 208 0.171
anatomical structure morphogenesis GO:0009653 298 0.170
apoptotic process GO:0006915 381 0.167
Rat
regulation of secretion GO:0051046 224 0.161
homeostatic process GO:0042592 331 0.157
cellular response to peptide GO:1901653 133 0.137
g protein coupled receptor signaling pathway GO:0007186 242 0.134
cellular response to hormone stimulus GO:0032870 247 0.131
regulation of system process GO:0044057 208 0.129
positive regulation of multicellular organismal process GO:0051240 387 0.125
organic acid metabolic process GO:0006082 292 0.123
blood circulation GO:0008015 183 0.120
positive regulation of response to stimulus GO:0048584 285 0.117
regulation of peptide secretion GO:0002791 82 0.112
chemical homeostasis GO:0048878 292 0.108
regulation of cellular component organization GO:0051128 368 0.103
positive regulation of cell communication GO:0010647 271 0.101
response to inorganic substance GO:0010035 377 0.101
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.100
secretion GO:0046903 307 0.098
neurological system process GO:0050877 219 0.097
cellular response to peptide hormone stimulus GO:0071375 120 0.096
urinary tract smooth muscle contraction GO:0014848 4 0.089
circulatory system process GO:0003013 183 0.088
response to peptide hormone GO:0043434 278 0.085
regulation of response to external stimulus GO:0032101 106 0.084
regulation of rna biosynthetic process GO:2001141 381 0.082
regulation of blood pressure GO:0008217 83 0.077
oxoacid metabolic process GO:0043436 290 0.075
positive regulation of peptide hormone secretion GO:0090277 50 0.073
nitrogen compound transport GO:0071705 229 0.073
regulation of body fluid levels GO:0050878 90 0.071
negative regulation of biosynthetic process GO:0009890 168 0.071
cellular response to organic cyclic compound GO:0071407 202 0.070
response to alkaloid GO:0043279 132 0.070
regulation of peptide transport GO:0090087 87 0.069
regulation of saliva secretion GO:0046877 3 0.069
protein phosphorylation GO:0006468 345 0.069
response to purine containing compound GO:0014074 126 0.069
positive regulation of transport GO:0051050 245 0.068
cation homeostasis GO:0055080 195 0.067
behavior GO:0007610 205 0.066
peptide secretion GO:0002790 86 0.065
positive regulation of secretion by cell GO:1903532 128 0.065
cation transport GO:0006812 382 0.064
regulation of blood vessel size GO:0050880 89 0.063
inflammatory response GO:0006954 150 0.063
programmed cell death GO:0012501 392 0.062
Rat
cellular response to nitrogen compound GO:1901699 210 0.062
tissue development GO:0009888 252 0.061
Rat
cellular response to oxygen containing compound GO:1901701 386 0.060
single organism reproductive process GO:0044702 297 0.060
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.060
response to growth factor GO:0070848 189 0.060
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.059
response to corticosteroid GO:0031960 235 0.059
response to wounding GO:0009611 254 0.059
Rat
regulation of rna metabolic process GO:0051252 391 0.058
negative regulation of gene expression GO:0010629 199 0.057
cell cell signaling GO:0007267 335 0.057
saliva secretion GO:0046541 3 0.056
regulation of hormone secretion GO:0046883 106 0.056
negative regulation of rna metabolic process GO:0051253 123 0.056
synaptic transmission glutamatergic GO:0035249 33 0.055
heart contraction GO:0060047 57 0.053
hormone transport GO:0009914 121 0.052
renal system process GO:0003014 40 0.052
response to camp GO:0051591 91 0.052
response to nutrient GO:0007584 248 0.051
defense response GO:0006952 194 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.050
negative regulation of transcription dna templated GO:0045892 116 0.050
aging GO:0007568 241 0.050
hormone secretion GO:0046879 115 0.049
rna biosynthetic process GO:0032774 380 0.049
organic substance catabolic process GO:1901575 316 0.049
sensory perception GO:0007600 101 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.048
cellular response to lipid GO:0071396 201 0.048
secretion by cell GO:0032940 248 0.047
positive regulation of peptide secretion GO:0002793 52 0.047
negative regulation of rna biosynthetic process GO:1902679 118 0.047
peristalsis GO:0030432 2 0.046
positive regulation of rna metabolic process GO:0051254 203 0.045
urinary bladder smooth muscle contraction GO:0014832 4 0.045
reproduction GO:0000003 245 0.045
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.045
single organism catabolic process GO:0044712 283 0.045
renal sodium excretion GO:0035812 20 0.044
central nervous system development GO:0007417 311 0.044
cell migration GO:0016477 197 0.044
negative regulation of cell death GO:0060548 229 0.044
Rat
peptide hormone secretion GO:0030072 84 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
signal release GO:0023061 145 0.043
multicellular organism reproduction GO:0032504 233 0.043
Rat
cellular chemical homeostasis GO:0055082 247 0.043
cellular response to glucocorticoid stimulus GO:0071385 68 0.043
response to hexose GO:0009746 144 0.043
vascular process in circulatory system GO:0003018 96 0.042
positive regulation of hormone secretion GO:0046887 65 0.042
phasic smooth muscle contraction GO:0014821 3 0.042
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.042
single organism biosynthetic process GO:0044711 342 0.041
cellular response to alcohol GO:0097306 87 0.041
ribonucleotide catabolic process GO:0009261 136 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.041
response to peptide GO:1901652 292 0.041
cellular calcium ion homeostasis GO:0006874 160 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.040
gland development GO:0048732 155 0.040
neuron neuron synaptic transmission GO:0007270 60 0.040
cellular component movement GO:0006928 248 0.040
brain renin angiotensin system GO:0002035 3 0.039
cellular metal ion homeostasis GO:0006875 172 0.039
cellular response to organonitrogen compound GO:0071417 197 0.039
response to glucose GO:0009749 136 0.039
regulation of transcription dna templated GO:0006355 374 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
cellular response to corticosteroid stimulus GO:0071384 69 0.039
response to extracellular stimulus GO:0009991 380 0.038
catabolic process GO:0009056 351 0.038
negative regulation of metabolic process GO:0009892 331 0.038
tube development GO:0035295 89 0.038
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of signaling GO:0023056 270 0.038
positive regulation of saliva secretion GO:0046878 3 0.037
positive regulation of blood circulation GO:1903524 65 0.037
locomotion GO:0040011 237 0.036
regulation of peptide hormone secretion GO:0090276 80 0.036
response to glucocorticoid GO:0051384 223 0.036
response to ketone GO:1901654 182 0.036
regulation of heart contraction GO:0008016 48 0.036
regulation of ion transport GO:0043269 245 0.036
muscle system process GO:0003012 115 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
purine nucleotide metabolic process GO:0006163 229 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
nucleic acid templated transcription GO:0097659 379 0.035
response to mechanical stimulus GO:0009612 134 0.034
acute inflammatory response GO:0002526 58 0.034
peptide transport GO:0015833 97 0.034
rhythmic process GO:0048511 156 0.034
response to dexamethasone GO:0071548 49 0.034
regulation of excretion GO:0044062 21 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
cellular ketone metabolic process GO:0042180 51 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
reproductive process GO:0022414 372 0.033
Rat
positive regulation of developmental process GO:0051094 283 0.033
amide transport GO:0042886 105 0.033
neuropeptide signaling pathway GO:0007218 29 0.033
rna metabolic process GO:0016070 406 0.032
regulation of cellular localization GO:0060341 263 0.032
response to organophosphorus GO:0046683 102 0.032
response to monosaccharide GO:0034284 159 0.031
positive regulation of secretion GO:0051047 140 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
regulation of amine transport GO:0051952 54 0.030
response to hypoxia GO:0001666 231 0.030
heart morphogenesis GO:0003007 3 0.030
response to cocaine GO:0042220 39 0.030
response to vitamin GO:0033273 131 0.030
transcription dna templated GO:0006351 377 0.030
organelle organization GO:0006996 266 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
regulation of hormone levels GO:0010817 187 0.029
angiotensin mediated drinking behavior GO:0003051 2 0.029
negative regulation of transport GO:0051051 136 0.029
positive regulation of signal transduction GO:0009967 175 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
response to estrogen GO:0043627 232 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
amine metabolic process GO:0009308 38 0.028
reproductive structure development GO:0048608 128 0.028
negative regulation of secretion GO:0051048 82 0.028
purine containing compound catabolic process GO:0072523 138 0.027
regulation of muscle system process GO:0090257 79 0.027
positive regulation of synaptic transmission GO:0050806 62 0.027
localization of cell GO:0051674 202 0.027
cardiovascular system development GO:0072358 134 0.027
cellular response to stress GO:0033554 269 0.027
regulation of blood circulation GO:1903522 110 0.027
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.027
vasoconstriction GO:0042310 54 0.027
positive regulation of gene expression GO:0010628 244 0.026
b cell mediated immunity GO:0019724 4 0.026
regulation of smooth muscle cell proliferation GO:0048660 75 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
response to estradiol GO:0032355 164 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
smooth muscle cell proliferation GO:0048659 77 0.026
regulation of transmembrane transport GO:0034762 122 0.025
nucleotide metabolic process GO:0009117 279 0.025
response to insulin GO:0032868 133 0.025
regulation of response to stress GO:0080134 126 0.025
secretion by tissue GO:0032941 37 0.025
wound healing GO:0042060 122 0.025
Rat
regulation of anatomical structure size GO:0090066 135 0.025
mapk cascade GO:0000165 140 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
regulation of apoptotic process GO:0042981 335 0.024
Rat
muscle cell proliferation GO:0033002 84 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
response to nutrient levels GO:0031667 370 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
aromatic compound catabolic process GO:0019439 168 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
positive regulation of nervous system development GO:0051962 178 0.024
glucose homeostasis GO:0042593 75 0.023
artery smooth muscle contraction GO:0014824 4 0.023
regulation of immune system process GO:0002682 123 0.023
neuron differentiation GO:0030182 368 0.023
regulation of response to wounding GO:1903034 69 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
Rat
metal ion transport GO:0030001 289 0.023
response to carbohydrate GO:0009743 183 0.023
regulation of renal sodium excretion GO:0035813 20 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.022
cellular response to external stimulus GO:0071496 118 0.022
liver development GO:0001889 90 0.022
epithelium development GO:0060429 96 0.022
ion homeostasis GO:0050801 212 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of cell proliferation GO:0042127 359 0.022
mesoderm development GO:0007498 2 0.022
learning or memory GO:0007611 90 0.022
gastrulation GO:0007369 2 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
cellular homeostasis GO:0019725 252 0.022
organ regeneration GO:0031100 101 0.022
mesonephros development GO:0001823 14 0.022
cytoskeleton organization GO:0007010 111 0.022
smooth muscle contraction GO:0006939 37 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
response to oxygen levels GO:0070482 265 0.021
regulation of molecular function GO:0065009 398 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
regulation of protein metabolic process GO:0051246 289 0.021
regulation of programmed cell death GO:0043067 341 0.021
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.021
mesonephric epithelium development GO:0072163 14 0.021
positive regulation of long term synaptic potentiation GO:1900273 4 0.021
response to ammonium ion GO:0060359 71 0.021
positive regulation of renal sodium excretion GO:0035815 10 0.021
reactive oxygen species metabolic process GO:0072593 37 0.020
ribose phosphate biosynthetic process GO:0046390 87 0.020
cell adhesion GO:0007155 110 0.020
tonic smooth muscle contraction GO:0014820 4 0.020
regulation of vasoconstriction GO:0019229 44 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
muscle structure development GO:0061061 87 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
Rat
connective tissue development GO:0061448 33 0.020
regulation of growth GO:0040008 105 0.020
regulation of neurological system process GO:0031644 43 0.020
regulation of cell growth GO:0001558 85 0.019
immune system process GO:0002376 204 0.019
hepaticobiliary system development GO:0061008 90 0.019
regulation of hydrolase activity GO:0051336 143 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
regulation of tube size GO:0035150 89 0.019
erk1 and erk2 cascade GO:0070371 48 0.019
single organism organelle organization GO:1902589 180 0.019
ribonucleoside monophosphate metabolic process GO:0009161 88 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
regeneration GO:0031099 163 0.018
Rat
organophosphate metabolic process GO:0019637 370 0.018
small molecule biosynthetic process GO:0044283 124 0.018
neuron projection development GO:0031175 273 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
ovulation cycle process GO:0022602 50 0.018
positive regulation of molecular function GO:0044093 230 0.018
intracellular signal transduction GO:0035556 314 0.018
sensory perception of pain GO:0019233 73 0.018
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.018
regulation of protein kinase activity GO:0045859 105 0.018
cellular cation homeostasis GO:0030003 180 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
response to metal ion GO:0010038 253 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
developmental process involved in reproduction GO:0003006 159 0.017
metal ion homeostasis GO:0055065 186 0.017
ossification GO:0001503 70 0.017
calcium ion homeostasis GO:0055074 162 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of membrane potential GO:0042391 110 0.017
organic hydroxy compound transport GO:0015850 77 0.017
vasodilation GO:0042311 44 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
anterior posterior pattern specification GO:0009952 1 0.017
cellular amino acid metabolic process GO:0006520 107 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cell motility GO:0048870 202 0.016
muscle cell differentiation GO:0042692 52 0.016
sodium ion transport GO:0006814 82 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
response to starvation GO:0042594 59 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cellular hormone metabolic process GO:0034754 49 0.016
multicellular organismal homeostasis GO:0048871 49 0.016
protein complex subunit organization GO:0071822 302 0.016
endocrine process GO:0050886 32 0.016
monocarboxylic acid biosynthetic process GO:0072330 48 0.016
positive regulation of growth GO:0045927 55 0.016
single organism intracellular transport GO:1902582 166 0.016
body fluid secretion GO:0007589 41 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
response to oxidative stress GO:0006979 186 0.016
reproductive system development GO:0061458 128 0.016
divalent inorganic cation transport GO:0072511 134 0.016
sexual reproduction GO:0019953 148 0.015
Rat
regulation of defense response GO:0031347 68 0.015
positive regulation of blood pressure GO:0045777 31 0.015
regulation of cell development GO:0060284 263 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of platelet activation GO:0010543 2 0.015
kidney development GO:0001822 67 0.015
regulation of vasodilation GO:0042312 36 0.015
regulation of sensory perception of pain GO:0051930 29 0.015
urogenital system development GO:0001655 78 0.015
single organism behavior GO:0044708 130 0.015
regulation of signal transduction GO:0009966 318 0.015
divalent metal ion transport GO:0070838 132 0.015
carbohydrate metabolic process GO:0005975 130 0.015
response to decreased oxygen levels GO:0036293 237 0.015
lipid biosynthetic process GO:0008610 128 0.015
proteolysis GO:0006508 175 0.015
Rat
renal system development GO:0072001 67 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
olfactory behavior GO:0042048 2 0.015
response to ethanol GO:0045471 162 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
norepinephrine secretion GO:0048243 16 0.015
positive regulation of locomotion GO:0040017 102 0.015
negative regulation of secretion by cell GO:1903531 72 0.015
regulation of insulin secretion GO:0050796 65 0.015
positive regulation of vasodilation GO:0045909 29 0.015
forebrain development GO:0030900 98 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
protein complex assembly GO:0006461 263 0.015
protein localization GO:0008104 191 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
purine nucleotide catabolic process GO:0006195 136 0.014
response to increased oxygen levels GO:0036296 45 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
positive regulation of heart contraction GO:0045823 15 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
formation of primary germ layer GO:0001704 1 0.014
developmental growth GO:0048589 100 0.014
Rat
positive regulation of digestive system process GO:0060456 8 0.014
n methyl d aspartate receptor clustering GO:0097114 2 0.014
fatty acid oxidation GO:0019395 29 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
neuron development GO:0048666 286 0.014
multi multicellular organism process GO:0044706 138 0.014
feeding behavior GO:0007631 53 0.014
negative regulation of hormone secretion GO:0046888 46 0.014
amine transport GO:0015837 57 0.014
multi organism reproductive process GO:0044703 262 0.014
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.014
regulation of calcium ion transport GO:0051924 77 0.014
cellular ion homeostasis GO:0006873 184 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
excretion GO:0007588 24 0.014
regulation of anion transport GO:0044070 43 0.013
extracellular matrix constituent secretion GO:0070278 4 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
response to acid chemical GO:0001101 222 0.013
drinking behavior GO:0042756 11 0.013
actin filament based movement GO:0030048 16 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of innate immune response GO:0045824 4 0.013
embryonic skeletal system development GO:0048706 3 0.013
intracellular transport GO:0046907 185 0.013
digestive system process GO:0022600 24 0.013
synaptic transmission cholinergic GO:0007271 11 0.013
regulation of synaptic transmission glutamatergic GO:0051966 26 0.013
cellular component assembly GO:0022607 360 0.013
palate development GO:0060021 2 0.013
regulation of protein modification process GO:0031399 194 0.013
glial cell differentiation GO:0010001 65 0.013
gliogenesis GO:0042063 93 0.013
cofactor metabolic process GO:0051186 95 0.013
catecholamine secretion GO:0050432 33 0.013
cell projection organization GO:0030030 302 0.013
cofactor biosynthetic process GO:0051188 28 0.013
cellular component biogenesis GO:0044085 368 0.013
ras protein signal transduction GO:0007265 29 0.013
organophosphate catabolic process GO:0046434 148 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
cognition GO:0050890 92 0.013
response to antibiotic GO:0046677 39 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
ureteric bud development GO:0001657 14 0.013
cell growth GO:0016049 104 0.013
actin filament based process GO:0030029 86 0.013
spermatogenesis GO:0007283 99 0.012
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.012
behavioral response to ethanol GO:0048149 1 0.012
branching morphogenesis of an epithelial tube GO:0048754 14 0.012
positive regulation of somatostatin secretion GO:0090274 4 0.012
synaptic transmission GO:0007268 235 0.012
epithelial cell proliferation GO:0050673 54 0.012
transmission of nerve impulse GO:0019226 42 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
mesonephric tubule development GO:0072164 14 0.012
protein maturation GO:0051604 68 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
macromolecular complex assembly GO:0065003 273 0.012
response to amino acid GO:0043200 75 0.012
cellular response to camp GO:0071320 26 0.012
endocrine system development GO:0035270 30 0.012
positive regulation of kinase activity GO:0033674 77 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
monoamine transport GO:0015844 43 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
involuntary skeletal muscle contraction GO:0003011 2 0.012
immunoglobulin mediated immune response GO:0016064 4 0.012
regulation of catalytic activity GO:0050790 304 0.012
circulatory system development GO:0072359 134 0.012
ovulation cycle GO:0042698 67 0.012
regulation of neuron differentiation GO:0045664 208 0.012
chemosensory behavior GO:0007635 2 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
fertilization GO:0009566 3 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
response to bacterium GO:0009617 200 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of systemic arterial blood pressure GO:0003073 30 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
fatty acid biosynthetic process GO:0006633 33 0.011
regulation of ion homeostasis GO:2000021 63 0.011
respiratory system process GO:0003016 3 0.011
regulation of locomotion GO:0040012 148 0.011
thyroid gland development GO:0030878 1 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
Rat
cellular response to insulin stimulus GO:0032869 81 0.011
regulation of nervous system development GO:0051960 264 0.011
heterocycle catabolic process GO:0046700 167 0.011
purine containing compound metabolic process GO:0072521 253 0.011
carbohydrate homeostasis GO:0033500 75 0.011
positive regulation of ion transport GO:0043270 94 0.011
insulin secretion GO:0030073 69 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
cellular response to ketone GO:1901655 51 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
nucleoside metabolic process GO:0009116 179 0.011

Adam5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
primary ciliary dyskinesia DOID:9562 0 0.317
disease of anatomical entity DOID:7 0 0.041
urinary system disease DOID:18 0 0.041
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
central nervous system disease DOID:331 0 0.016
brain disease DOID:936 0 0.016
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012