Rattus norvegicus

20 known processes

Adamts13

ADAM metallopeptidase with thrombospondin type 1 motif, 13

Adamts13 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.188
intracellular signal transduction GO:0035556 314 0.118
regulation of rna metabolic process GO:0051252 391 0.104
carboxylic acid metabolic process GO:0019752 289 0.099
regulation of signal transduction GO:0009966 318 0.098
regulation of multicellular organismal development GO:2000026 376 0.083
organic acid metabolic process GO:0006082 292 0.082
hormone secretion GO:0046879 115 0.079
regulation of mapk cascade GO:0043408 116 0.075
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.074
rna biosynthetic process GO:0032774 380 0.072
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.071
regulation of phosphorylation GO:0042325 248 0.063
positive regulation of signal transduction GO:0009967 175 0.062
protein phosphorylation GO:0006468 345 0.060
tube development GO:0035295 89 0.059
positive regulation of cell communication GO:0010647 271 0.058
regulation of phosphate metabolic process GO:0019220 349 0.057
developmental induction GO:0031128 2 0.056
cell cell signaling GO:0007267 335 0.055
regulation of rna biosynthetic process GO:2001141 381 0.054
positive regulation of rna biosynthetic process GO:1902680 197 0.054
transcription from rna polymerase ii promoter GO:0006366 252 0.053
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
single organism reproductive process GO:0044702 297 0.052
reproduction GO:0000003 245 0.051
cellular ketone metabolic process GO:0042180 51 0.050
cell projection organization GO:0030030 302 0.049
regulation of cell projection organization GO:0031344 175 0.047
cellular amino acid metabolic process GO:0006520 107 0.047
inorganic ion transmembrane transport GO:0098660 229 0.046
enzyme linked receptor protein signaling pathway GO:0007167 116 0.046
regulation of cellular ketone metabolic process GO:0010565 27 0.045
regulation of secretion by cell GO:1903530 208 0.045
regulation of transcription dna templated GO:0006355 374 0.045
inorganic cation transmembrane transport GO:0098662 202 0.044
regulation of nervous system development GO:0051960 264 0.042
regulation of neuron projection development GO:0010975 161 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
response to inorganic substance GO:0010035 377 0.041
anatomical structure morphogenesis GO:0009653 298 0.040
negative regulation of apoptotic process GO:0043066 181 0.040
tissue development GO:0009888 252 0.040
nucleic acid templated transcription GO:0097659 379 0.040
positive regulation of signaling GO:0023056 270 0.039
heart contraction GO:0060047 57 0.038
multicellular organism reproduction GO:0032504 233 0.037
positive regulation of gene expression GO:0010628 244 0.037
cellular response to organic cyclic compound GO:0071407 202 0.037
regulation of organ formation GO:0003156 2 0.037
positive regulation of nervous system development GO:0051962 178 0.036
cellular lipid metabolic process GO:0044255 208 0.036
cellular amine metabolic process GO:0044106 38 0.036
regulation of secretion GO:0051046 224 0.036
positive regulation of rna metabolic process GO:0051254 203 0.035
heart process GO:0003015 57 0.035
regulation of cellular component organization GO:0051128 368 0.035
oxoacid metabolic process GO:0043436 290 0.035
negative regulation of transport GO:0051051 136 0.034
positive regulation of heart contraction GO:0045823 15 0.034
regulation of hormone secretion GO:0046883 106 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of peptide transport GO:0090087 87 0.032
hormone transport GO:0009914 121 0.032
transmembrane transport GO:0055085 412 0.032
neuron projection development GO:0031175 273 0.031
regeneration GO:0031099 163 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
cellular component biogenesis GO:0044085 368 0.031
positive regulation of developmental process GO:0051094 283 0.030
regulation of programmed cell death GO:0043067 341 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
programmed cell death GO:0012501 392 0.030
positive regulation of intracellular signal transduction GO:1902533 138 0.030
amide transport GO:0042886 105 0.029
cell migration GO:0016477 197 0.029
negative regulation of cell communication GO:0010648 158 0.029
secretion by cell GO:0032940 248 0.029
lipid metabolic process GO:0006629 283 0.029
response to monosaccharide GO:0034284 159 0.029
cellular response to growth factor stimulus GO:0071363 162 0.029
organ induction GO:0001759 1 0.028
regulation of membrane potential GO:0042391 110 0.028
neuron development GO:0048666 286 0.028
rna metabolic process GO:0016070 406 0.028
response to peptide GO:1901652 292 0.028
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
development of primary sexual characteristics GO:0045137 107 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
circulatory system process GO:0003013 183 0.027
response to cytokine GO:0034097 215 0.027
amine metabolic process GO:0009308 38 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
response to glucose GO:0009749 136 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
action potential GO:0001508 54 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
regulation of molecular function GO:0065009 398 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
response to peptide hormone GO:0043434 278 0.027
protein complex biogenesis GO:0070271 263 0.026
response to growth factor GO:0070848 189 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
regulation of protein modification process GO:0031399 194 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of catalytic activity GO:0050790 304 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cellular catabolic process GO:0044248 295 0.024
neuron differentiation GO:0030182 368 0.024
regulation of cell proliferation GO:0042127 359 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
regulation of apoptotic process GO:0042981 335 0.024
regulation of blood circulation GO:1903522 110 0.023
regulation of body fluid levels GO:0050878 90 0.023
signal release GO:0023061 145 0.023
small molecule biosynthetic process GO:0044283 124 0.023
gonad development GO:0008406 104 0.023
response to extracellular stimulus GO:0009991 380 0.023
carbohydrate metabolic process GO:0005975 130 0.023
multi organism reproductive process GO:0044703 262 0.022
coronary vasculature morphogenesis GO:0060977 3 0.022
positive regulation of hormone secretion GO:0046887 65 0.022
mapk cascade GO:0000165 140 0.022
regulation of cellular response to stress GO:0080135 49 0.022
transcription dna templated GO:0006351 377 0.022
regulation of neuron differentiation GO:0045664 208 0.022
cellular component assembly GO:0022607 360 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
sodium ion transport GO:0006814 82 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
circulatory system development GO:0072359 134 0.021
regulation of hormone levels GO:0010817 187 0.020
monosaccharide metabolic process GO:0005996 61 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
cell motility GO:0048870 202 0.020
regulation of cardiac muscle tissue development GO:0055024 12 0.020
chemical homeostasis GO:0048878 292 0.020
cardiac muscle contraction GO:0060048 27 0.020
ion transmembrane transport GO:0034220 365 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
regulation of cell migration GO:0030334 128 0.020
positive regulation of cell development GO:0010720 176 0.020
phosphatidylcholine biosynthetic process GO:0006656 5 0.020
macromolecular complex assembly GO:0065003 273 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
regulation of cellular localization GO:0060341 263 0.019
cellular component movement GO:0006928 248 0.019
specification of organ identity GO:0010092 2 0.019
metal ion transport GO:0030001 289 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of signaling GO:0023057 157 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
response to acid chemical GO:0001101 222 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
regulation of metal ion transport GO:0010959 118 0.018
lipid biosynthetic process GO:0008610 128 0.018
response to hexose GO:0009746 144 0.018
locomotion GO:0040011 237 0.018
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.018
regulation of ion transport GO:0043269 245 0.017
tube formation GO:0035148 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
apoptotic process GO:0006915 381 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
regulation of homeostatic process GO:0032844 101 0.017
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.017
regulation of peptide hormone secretion GO:0090276 80 0.017
regulation of cell differentiation GO:0045595 320 0.017
cellular ion homeostasis GO:0006873 184 0.017
ovulation cycle process GO:0022602 50 0.017
muscle cell proliferation GO:0033002 84 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
homeostatic process GO:0042592 331 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
negative regulation of metabolic process GO:0009892 331 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
cation transport GO:0006812 382 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
localization of cell GO:0051674 202 0.015
regulation of peptide secretion GO:0002791 82 0.015
catabolic process GO:0009056 351 0.015
regulation of growth GO:0040008 105 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
organelle organization GO:0006996 266 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
ovarian follicle development GO:0001541 31 0.015
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
response to ketone GO:1901654 182 0.015
spermatogenesis GO:0007283 99 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of peptide hormone secretion GO:0090277 50 0.015
reactive oxygen species metabolic process GO:0072593 37 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
cation transmembrane transport GO:0098655 263 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
ion homeostasis GO:0050801 212 0.014
heart development GO:0007507 72 0.014
positive regulation of secretion GO:0051047 140 0.014
gamete generation GO:0007276 124 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
ras protein signal transduction GO:0007265 29 0.014
response to toxic substance GO:0009636 133 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
rhythmic process GO:0048511 156 0.014
ovulation cycle GO:0042698 67 0.014
male gamete generation GO:0048232 99 0.014
response to wounding GO:0009611 254 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of immunoglobulin production GO:0002637 4 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.013
regulation of heart growth GO:0060420 12 0.013
cofactor metabolic process GO:0051186 95 0.013
organ morphogenesis GO:0009887 75 0.013
mesoderm development GO:0007498 2 0.013
peptide hormone secretion GO:0030072 84 0.013
response to estrogen GO:0043627 232 0.013
regulation of developmental growth GO:0048638 45 0.013
secretion GO:0046903 307 0.013
regulation of cell motility GO:2000145 131 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
pancreatic stellate cell proliferation GO:0072343 2 0.013
response to nutrient levels GO:0031667 370 0.013
peptidyl amino acid modification GO:0018193 126 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
response to nutrient GO:0007584 248 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.012
positive regulation of cell death GO:0010942 184 0.012
regulation of cellular component movement GO:0051270 150 0.012
sulfur compound metabolic process GO:0006790 70 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
insulin secretion GO:0030073 69 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
organic acid transport GO:0015849 116 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
positive regulation of molecular function GO:0044093 230 0.011
reproductive process GO:0022414 372 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
angiogenesis GO:0001525 53 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
organ regeneration GO:0031100 101 0.011
regulation of striated muscle tissue development GO:0016202 25 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
brown fat cell proliferation GO:0070342 2 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
anion transport GO:0006820 178 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
response to purine containing compound GO:0014074 126 0.011
reproductive structure development GO:0048608 128 0.011
cytolysis GO:0019835 4 0.011
sexual reproduction GO:0019953 148 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
muscle contraction GO:0006936 88 0.011
blood vessel development GO:0001568 69 0.011
peptide secretion GO:0002790 86 0.011
regulation of heart contraction GO:0008016 48 0.010
positive regulation of protein modification process GO:0031401 142 0.010
central nervous system development GO:0007417 311 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
axis specification GO:0009798 4 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
regulation of catabolic process GO:0009894 113 0.010
negative regulation of signal transduction GO:0009968 83 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010

Adamts13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.015