Rattus norvegicus

0 known processes

Adhfe1

alcohol dehydrogenase, iron containing, 1

Adhfe1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.670
alpha amino acid metabolic process GO:1901605 71 0.653
organic acid metabolic process GO:0006082 292 0.604
cellular amino acid metabolic process GO:0006520 107 0.377
oxoacid metabolic process GO:0043436 290 0.306
cellular amino acid catabolic process GO:0009063 21 0.275
response to peptide GO:1901652 292 0.159
cellular ketone metabolic process GO:0042180 51 0.142
cellular response to nitrogen compound GO:1901699 210 0.136
small molecule catabolic process GO:0044282 59 0.133
cellular catabolic process GO:0044248 295 0.124
response to inorganic substance GO:0010035 377 0.120
response to peptide hormone GO:0043434 278 0.107
organic acid catabolic process GO:0016054 49 0.105
branched chain amino acid metabolic process GO:0009081 4 0.100
blood circulation GO:0008015 183 0.099
response to extracellular stimulus GO:0009991 380 0.091
lipid metabolic process GO:0006629 283 0.091
cofactor metabolic process GO:0051186 95 0.090
monocarboxylic acid metabolic process GO:0032787 152 0.089
intracellular signal transduction GO:0035556 314 0.087
cellular response to organonitrogen compound GO:0071417 197 0.085
negative regulation of cell communication GO:0010648 158 0.079
carboxylic acid catabolic process GO:0046395 49 0.079
catabolic process GO:0009056 351 0.077
regulation of cellular amino acid metabolic process GO:0006521 2 0.075
amine metabolic process GO:0009308 38 0.074
chemical homeostasis GO:0048878 292 0.073
alpha amino acid catabolic process GO:1901606 20 0.072
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
carbohydrate derivative metabolic process GO:1901135 346 0.068
positive regulation of multicellular organismal process GO:0051240 387 0.067
regulation of rna metabolic process GO:0051252 391 0.066
regulation of cellular ketone metabolic process GO:0010565 27 0.065
coenzyme metabolic process GO:0006732 86 0.063
cellular amine metabolic process GO:0044106 38 0.060
single organism catabolic process GO:0044712 283 0.059
nucleic acid templated transcription GO:0097659 379 0.059
organic substance catabolic process GO:1901575 316 0.058
regulation of cell proliferation GO:0042127 359 0.057
negative regulation of signaling GO:0023057 157 0.055
response to insulin GO:0032868 133 0.053
naphthalene metabolic process GO:0018931 2 0.052
oxidation reduction process GO:0055114 304 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.051
regulation of cellular localization GO:0060341 263 0.050
aromatic amino acid family catabolic process GO:0009074 7 0.050
regulation of rna biosynthetic process GO:2001141 381 0.049
branched chain amino acid catabolic process GO:0009083 4 0.049
valine metabolic process GO:0006573 1 0.049
regulation of secretion by cell GO:1903530 208 0.047
regulation of intracellular signal transduction GO:1902531 218 0.047
acyl coa metabolic process GO:0006637 28 0.046
fatty acid metabolic process GO:0006631 99 0.046
rna biosynthetic process GO:0032774 380 0.045
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
single organism reproductive process GO:0044702 297 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
response to metal ion GO:0010038 253 0.044
response to ketone GO:1901654 182 0.043
rna metabolic process GO:0016070 406 0.043
circulatory system process GO:0003013 183 0.043
cellular response to peptide hormone stimulus GO:0071375 120 0.042
lipid biosynthetic process GO:0008610 128 0.042
positive regulation of biosynthetic process GO:0009891 319 0.042
regulation of protein modification process GO:0031399 194 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
organonitrogen compound catabolic process GO:1901565 179 0.041
response to nutrient levels GO:0031667 370 0.040
negative regulation of metabolic process GO:0009892 331 0.040
response to purine containing compound GO:0014074 126 0.039
cellular response to peptide GO:1901653 133 0.039
aging GO:0007568 241 0.039
transcription dna templated GO:0006351 377 0.038
regulation of phosphorylation GO:0042325 248 0.038
organic cyclic compound catabolic process GO:1901361 175 0.038
regulation of cell differentiation GO:0045595 320 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
positive regulation of rna metabolic process GO:0051254 203 0.037
homeostatic process GO:0042592 331 0.037
immune system process GO:0002376 204 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
cellular response to stress GO:0033554 269 0.036
regulation of secretion GO:0051046 224 0.036
organic hydroxy compound biosynthetic process GO:1901617 51 0.035
halogenated hydrocarbon metabolic process GO:0042197 4 0.035
hormone transport GO:0009914 121 0.035
cellular response to organic cyclic compound GO:0071407 202 0.034
nitrogen compound transport GO:0071705 229 0.034
vitamin biosynthetic process GO:0009110 3 0.034
aromatic amino acid family metabolic process GO:0009072 9 0.034
naphthalene containing compound metabolic process GO:0090420 2 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of hormone levels GO:0010817 187 0.034
positive regulation of phosphorylation GO:0042327 177 0.034
negative regulation of biosynthetic process GO:0009890 168 0.033
regulation of lipid metabolic process GO:0019216 68 0.033
negative regulation of rna biosynthetic process GO:1902679 118 0.032
neuron development GO:0048666 286 0.032
positive regulation of cell communication GO:0010647 271 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
pyrimidine nucleobase catabolic process GO:0006208 3 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
positive regulation of peptide secretion GO:0002793 52 0.030
secretion by cell GO:0032940 248 0.030
sulfur compound biosynthetic process GO:0044272 19 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
regulation of mapk cascade GO:0043408 116 0.030
thioester metabolic process GO:0035383 28 0.030
purine containing compound metabolic process GO:0072521 253 0.030
defense response GO:0006952 194 0.030
muscle cell proliferation GO:0033002 84 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to alkaloid GO:0043279 132 0.028
single organism biosynthetic process GO:0044711 342 0.028
sulfur compound metabolic process GO:0006790 70 0.028
response to acid chemical GO:0001101 222 0.028
small molecule biosynthetic process GO:0044283 124 0.028
organophosphate metabolic process GO:0019637 370 0.028
positive regulation of developmental process GO:0051094 283 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
alkaloid metabolic process GO:0009820 3 0.027
nicotine metabolic process GO:0018933 1 0.026
lipid catabolic process GO:0016042 46 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
macromolecular complex assembly GO:0065003 273 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
peptidyl amino acid modification GO:0018193 126 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
cellular lipid metabolic process GO:0044255 208 0.025
cellular chemical homeostasis GO:0055082 247 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
heart morphogenesis GO:0003007 3 0.025
chlorinated hydrocarbon metabolic process GO:0042196 4 0.024
regulation of kinase activity GO:0043549 117 0.024
positive regulation of cell development GO:0010720 176 0.024
calcitriol biosynthetic process from calciol GO:0036378 2 0.023
cellular response to lipid GO:0071396 201 0.023
carbohydrate metabolic process GO:0005975 130 0.023
secretion GO:0046903 307 0.023
reproductive process GO:0022414 372 0.023
regulation of homeostatic process GO:0032844 101 0.023
positive regulation of nervous system development GO:0051962 178 0.023
lipid oxidation GO:0034440 30 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
response to oxidative stress GO:0006979 186 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.023
regulation of system process GO:0044057 208 0.023
negative regulation of rna metabolic process GO:0051253 123 0.022
regulation of molecular function GO:0065009 398 0.022
phospholipid metabolic process GO:0006644 61 0.022
ion transmembrane transport GO:0034220 365 0.022
peptide secretion GO:0002790 86 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
regulation of peptide hormone secretion GO:0090276 80 0.022
regulation of protein metabolic process GO:0051246 289 0.022
response to oxygen levels GO:0070482 265 0.022
neuron projection development GO:0031175 273 0.021
neuron differentiation GO:0030182 368 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
cellular modified amino acid metabolic process GO:0006575 61 0.021
transmembrane transport GO:0055085 412 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
insulin secretion GO:0030073 69 0.020
cation homeostasis GO:0055080 195 0.020
metal ion transport GO:0030001 289 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
thymine catabolic process GO:0006210 2 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
divalent metal ion transport GO:0070838 132 0.020
positive regulation of transport GO:0051050 245 0.020
cell projection organization GO:0030030 302 0.020
cellular response to cytokine stimulus GO:0071345 127 0.019
regulation of metal ion transport GO:0010959 118 0.019
regulation of hormone secretion GO:0046883 106 0.019
response to estrogen GO:0043627 232 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
monosaccharide metabolic process GO:0005996 61 0.019
response to corticosteroid GO:0031960 235 0.019
regulation of cell development GO:0060284 263 0.019
response to decreased oxygen levels GO:0036293 237 0.019
reproduction GO:0000003 245 0.019
signal release GO:0023061 145 0.018
calcium ion transport GO:0006816 131 0.018
drug metabolic process GO:0017144 11 0.018
response to reactive oxygen species GO:0000302 120 0.018
protein phosphorylation GO:0006468 345 0.018
negative regulation of gene expression GO:0010629 199 0.018
cellular response to external stimulus GO:0071496 118 0.018
negative regulation of transport GO:0051051 136 0.018
regulation of transcription dna templated GO:0006355 374 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
response to glucocorticoid GO:0051384 223 0.018
response to xenobiotic stimulus GO:0009410 23 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
nucleoside metabolic process GO:0009116 179 0.018
vitamin d metabolic process GO:0042359 4 0.018
developmental process involved in reproduction GO:0003006 159 0.018
peptide hormone secretion GO:0030072 84 0.017
regulation of nervous system development GO:0051960 264 0.017
trichloroethylene metabolic process GO:0018979 1 0.017
ion homeostasis GO:0050801 212 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
response to wounding GO:0009611 254 0.017
heterocycle catabolic process GO:0046700 167 0.017
cell cell signaling GO:0007267 335 0.017
cellular cation homeostasis GO:0030003 180 0.017
linoleic acid metabolic process GO:0043651 4 0.017
amide transport GO:0042886 105 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
circulatory system development GO:0072359 134 0.017
neutral lipid metabolic process GO:0006638 21 0.017
regulation of peptide transport GO:0090087 87 0.017
regulation of ion transport GO:0043269 245 0.017
response to cycloheximide GO:0046898 6 0.017
tissue development GO:0009888 252 0.016
response to cesium ion GO:0010164 2 0.016
fatty acid catabolic process GO:0009062 26 0.016
metal ion homeostasis GO:0055065 186 0.016
regulation of signal transduction GO:0009966 318 0.016
phenol containing compound metabolic process GO:0018958 30 0.016
positive regulation of triglyceride metabolic process GO:0090208 4 0.016
reproductive structure development GO:0048608 128 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
negative regulation of signal transduction GO:0009968 83 0.016
hepaticobiliary system development GO:0061008 90 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
lipid storage GO:0019915 1 0.016
cation transport GO:0006812 382 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
hormone secretion GO:0046879 115 0.016
sexual reproduction GO:0019953 148 0.016
female pregnancy GO:0007565 122 0.016
response to insecticide GO:0017085 21 0.016
regulation of transferase activity GO:0051338 123 0.016
response to hypoxia GO:0001666 231 0.016
divalent inorganic cation transport GO:0072511 134 0.016
response to calcium ion GO:0051592 59 0.016
negative regulation of transcription dna templated GO:0045892 116 0.015
response to biotic stimulus GO:0009607 226 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
serine family amino acid metabolic process GO:0009069 12 0.015
negative regulation of hormone secretion GO:0046888 46 0.015
muscle system process GO:0003012 115 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to monosaccharide GO:0034284 159 0.015
regulation of neurogenesis GO:0050767 247 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
multi organism reproductive process GO:0044703 262 0.015
thymine metabolic process GO:0019859 2 0.015
drug catabolic process GO:0042737 1 0.015
cellular homeostasis GO:0019725 252 0.015
cellular component biogenesis GO:0044085 368 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
pyrimidine nucleobase metabolic process GO:0006206 8 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
terpenoid metabolic process GO:0006721 37 0.015
development of primary sexual characteristics GO:0045137 107 0.015
chemosensory behavior GO:0007635 2 0.015
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of catabolic process GO:0009894 113 0.014
multicellular organism reproduction GO:0032504 233 0.014
vitamin d3 metabolic process GO:0070640 2 0.014
response to nutrient GO:0007584 248 0.014
pteridine containing compound metabolic process GO:0042558 14 0.014
response to vitamin e GO:0033197 24 0.014
positive regulation of signal transduction GO:0009967 175 0.014
hexose metabolic process GO:0019318 58 0.014
aromatic compound catabolic process GO:0019439 168 0.014
regulation of neuron death GO:1901214 115 0.014
regulation of response to stress GO:0080134 126 0.014
sex differentiation GO:0007548 113 0.014
triglyceride metabolic process GO:0006641 21 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
rhythmic process GO:0048511 156 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
activation of jak2 kinase activity GO:0042977 2 0.014
positive regulation of hormone secretion GO:0046887 65 0.014
negative regulation of intracellular signal transduction GO:1902532 38 0.014
cellular response to cycloheximide GO:0071409 4 0.014
negative regulation of innate immune response GO:0045824 4 0.014
erk1 and erk2 cascade GO:0070371 48 0.014
regulation of cell projection organization GO:0031344 175 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of peptide secretion GO:0002791 82 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
response to bacterium GO:0009617 200 0.013
multicellular organism growth GO:0035264 1 0.013
cardiovascular system development GO:0072358 134 0.013
organelle organization GO:0006996 266 0.013
response to hexose GO:0009746 144 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
secondary alcohol metabolic process GO:1902652 2 0.013
steroid metabolic process GO:0008202 73 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
regulation of insulin secretion GO:0050796 65 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cell type specific apoptotic process GO:0097285 134 0.013
positive regulation of immune response GO:0050778 42 0.013
epoxygenase p450 pathway GO:0019373 1 0.013
vitamin d biosynthetic process GO:0042368 2 0.013
regulation of triglyceride biosynthetic process GO:0010866 4 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
response to ethanol GO:0045471 162 0.013
tube development GO:0035295 89 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.012
positive regulation of immune system process GO:0002684 90 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
programmed cell death GO:0012501 392 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
chromosome segregation GO:0007059 2 0.012
regulation of catalytic activity GO:0050790 304 0.012
regulation of blood circulation GO:1903522 110 0.012
central nervous system development GO:0007417 311 0.012
lipid modification GO:0030258 52 0.012
cellular component assembly GO:0022607 360 0.012
exogenous drug catabolic process GO:0042738 1 0.012
response to sulfur dioxide GO:0010477 3 0.012
response to hydrogen peroxide GO:0042542 89 0.012
regulation of blood pressure GO:0008217 83 0.012
progesterone biosynthetic process GO:0006701 3 0.012
regulation of apoptotic process GO:0042981 335 0.012
c21 steroid hormone biosynthetic process GO:0006700 10 0.012
cellular response to vitamin e GO:0071306 3 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
olfactory learning GO:0008355 1 0.012
peptide transport GO:0015833 97 0.012
neuron death GO:0070997 127 0.012
neurological system process GO:0050877 219 0.012
nucleobase catabolic process GO:0046113 4 0.012
response to glucose GO:0009749 136 0.012
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.012
phenol containing compound biosynthetic process GO:0046189 9 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
regulation of neuron differentiation GO:0045664 208 0.012
carbohydrate homeostasis GO:0033500 75 0.011
response to temperature stimulus GO:0009266 94 0.011
glucose metabolic process GO:0006006 52 0.011
multi multicellular organism process GO:0044706 138 0.011
olfactory behavior GO:0042048 2 0.011
positive regulation of gene expression GO:0010628 244 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
apoptotic process GO:0006915 381 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
catechol containing compound biosynthetic process GO:0009713 9 0.011
response to organophosphorus GO:0046683 102 0.011
circadian rhythm GO:0007623 88 0.011
response to toxic substance GO:0009636 133 0.011
cofactor biosynthetic process GO:0051188 28 0.011
axis specification GO:0009798 4 0.011
sensory perception of bitter taste GO:0050913 4 0.011
circadian regulation of gene expression GO:0032922 3 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
lipid localization GO:0010876 62 0.011
regulation of cellular component organization GO:0051128 368 0.011
behavioral response to nicotine GO:0035095 2 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
pyrimidine containing compound metabolic process GO:0072527 20 0.011
unsaturated fatty acid metabolic process GO:0033559 39 0.011
negative regulation of cell death GO:0060548 229 0.011
fatty acid derivative metabolic process GO:1901568 38 0.011
alcohol biosynthetic process GO:0046165 38 0.011
regulation of carbohydrate metabolic process GO:0006109 41 0.011
cellular response to methylglyoxal GO:0097238 1 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of anatomical structure size GO:0090066 135 0.011
negative regulation of secretion GO:0051048 82 0.011
cellular ion homeostasis GO:0006873 184 0.011
response to molecule of fungal origin GO:0002238 3 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
cellular response to reactive oxygen species GO:0034614 55 0.010
cellular response to alcohol GO:0097306 87 0.010
maintenance of location GO:0051235 17 0.010
lauric acid metabolic process GO:0048252 4 0.010
mapk cascade GO:0000165 140 0.010
carbohydrate biosynthetic process GO:0016051 42 0.010
response to camp GO:0051591 91 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
acetyl coa metabolic process GO:0006084 17 0.010
negative regulation of collagen biosynthetic process GO:0032966 4 0.010
regulation of immune system process GO:0002682 123 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
regulation of transmembrane transport GO:0034762 122 0.010
response to testosterone GO:0033574 55 0.010
response to activity GO:0014823 73 0.010
proteolysis GO:0006508 175 0.010
heart development GO:0007507 72 0.010
xenobiotic metabolic process GO:0006805 19 0.010
acyl coa biosynthetic process GO:0071616 7 0.010
positive regulation of transferase activity GO:0051347 81 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
locomotor rhythm GO:0045475 1 0.010
positive regulation of lipid metabolic process GO:0045834 33 0.010

Adhfe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.034
disease of metabolism DOID:0014667 0 0.034
amino acid metabolic disorder DOID:9252 0 0.019
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.011