Rattus norvegicus

353 known processes

Adora2a

adenosine A2a receptor

(Aliases: A2ar,ADENO,MGC93190,Adora2l1)

Adora2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of intracellular signal transduction GO:1902531 218 0.860
Rat
prepulse inhibition GO:0060134 1 0.821
programmed cell death GO:0012501 392 0.788
g protein coupled receptor signaling pathway GO:0007186 242 0.771
metal ion homeostasis GO:0055065 186 0.715
regulation of cell development GO:0060284 263 0.692
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.678
regulation of synaptic transmission GO:0050804 141 0.664
positive regulation of multicellular organismal process GO:0051240 387 0.610
intracellular signal transduction GO:0035556 314 0.602
Rat
immune system process GO:0002376 204 0.594
Mouse
startle response GO:0001964 2 0.558
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.555
Rat
apoptotic process GO:0006915 381 0.548
positive regulation of response to stimulus GO:0048584 285 0.539
regulation of behavior GO:0050795 61 0.525
regulation of cell differentiation GO:0045595 320 0.518
regulation of synaptic plasticity GO:0048167 70 0.514
leukocyte activation GO:0045321 76 0.509
Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.508
regulation of homeostatic process GO:0032844 101 0.504
positive regulation of cell communication GO:0010647 271 0.503
regulation of locomotion GO:0040012 148 0.500
positive regulation of nucleotide metabolic process GO:0045981 91 0.493
Human Mouse Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.482
Human Mouse Rat
defense response GO:0006952 194 0.475
Mouse Rat
regulation of multicellular organismal development GO:2000026 376 0.472
Rat
cation homeostasis GO:0055080 195 0.469
synaptic transmission GO:0007268 235 0.469
signal transduction by phosphorylation GO:0023014 144 0.468
Rat
smooth muscle contraction GO:0006939 37 0.461
Rat
regulation of secretion by cell GO:1903530 208 0.454
positive regulation of signaling GO:0023056 270 0.450
cell cell signaling GO:0007267 335 0.448
positive regulation of intracellular signal transduction GO:1902533 138 0.433
Rat
mapk cascade GO:0000165 140 0.431
Rat
response to oxygen levels GO:0070482 265 0.431
Rat
regulation of signal transduction GO:0009966 318 0.427
Mouse Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.426
positive regulation of mapk cascade GO:0043410 92 0.420
Rat
organophosphate metabolic process GO:0019637 370 0.419
Human Mouse Rat
positive regulation of behavior GO:0048520 38 0.412
rna biosynthetic process GO:0032774 380 0.410
regulation of phosphorus metabolic process GO:0051174 349 0.396
positive regulation of cell proliferation GO:0008284 249 0.390
Rat
nucleic acid templated transcription GO:0097659 379 0.389
calcium ion homeostasis GO:0055074 162 0.383
negative regulation of response to stimulus GO:0048585 155 0.380
protein transport GO:0015031 132 0.379
positive regulation of synaptic transmission GO:0050806 62 0.378
rna metabolic process GO:0016070 406 0.374
negative regulation of signaling GO:0023057 157 0.366
Rat
regulation of nervous system development GO:0051960 264 0.363
positive regulation of nucleoside metabolic process GO:0045979 55 0.363
regulation of programmed cell death GO:0043067 341 0.360
positive regulation of homeostatic process GO:0032846 49 0.357
positive regulation of cell differentiation GO:0045597 217 0.356
cellular calcium ion homeostasis GO:0006874 160 0.355
regulation of rna metabolic process GO:0051252 391 0.354
regulation of cellular localization GO:0060341 263 0.341
inflammatory response GO:0006954 150 0.340
Mouse Rat
positive regulation of transport GO:0051050 245 0.336
secretion by cell GO:0032940 248 0.326
response to amine GO:0014075 46 0.323
Mouse
nitrogen compound transport GO:0071705 229 0.321
negative regulation of multicellular organismal process GO:0051241 203 0.318
Rat
homeostatic process GO:0042592 331 0.312
organonitrogen compound biosynthetic process GO:1901566 167 0.311
Human Mouse Rat
response to mechanical stimulus GO:0009612 134 0.310
purine nucleotide biosynthetic process GO:0006164 83 0.309
Human Mouse Rat
behavior GO:0007610 205 0.307
regulation of metal ion transport GO:0010959 118 0.305
regulation of vasculature development GO:1901342 44 0.302
Rat
regulation of molecular function GO:0065009 398 0.297
regulation of cellular component organization GO:0051128 368 0.296
stress activated protein kinase signaling cascade GO:0031098 37 0.296
regulation of nucleic acid templated transcription GO:1903506 380 0.295
divalent metal ion transport GO:0070838 132 0.290
muscle contraction GO:0006936 88 0.289
Rat
blood circulation GO:0008015 183 0.286
regulation of mapk cascade GO:0043408 116 0.284
Rat
amine transport GO:0015837 57 0.284
sensory perception GO:0007600 101 0.283
Rat
regulation of protein phosphorylation GO:0001932 183 0.279
regulation of catecholamine secretion GO:0050433 32 0.277
regulation of apoptotic process GO:0042981 335 0.276
organic substance catabolic process GO:1901575 316 0.269
Rat
cellular cation homeostasis GO:0030003 180 0.268
muscle system process GO:0003012 115 0.268
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.263
Human Mouse Rat
ribonucleotide metabolic process GO:0009259 231 0.263
Human Mouse Rat
carbohydrate derivative metabolic process GO:1901135 346 0.260
Human Mouse Rat
inflammatory response to antigenic stimulus GO:0002437 18 0.257
negative regulation of programmed cell death GO:0043069 183 0.255
ion homeostasis GO:0050801 212 0.254
divalent inorganic cation homeostasis GO:0072507 165 0.250
negative regulation of cell death GO:0060548 229 0.249
regulation of cellular protein metabolic process GO:0032268 267 0.249
cellular homeostasis GO:0019725 252 0.248
negative regulation of cellular metabolic process GO:0031324 281 0.248
regulation of neurological system process GO:0031644 43 0.247
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.245
positive regulation of catalytic activity GO:0043085 184 0.244
Human Rat
glutamate secretion GO:0014047 19 0.242
positive regulation of cell development GO:0010720 176 0.240
positive regulation of protein metabolic process GO:0051247 178 0.240
Rat
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.239
calcium ion transport GO:0006816 131 0.238
cellular ion homeostasis GO:0006873 184 0.234
neuron differentiation GO:0030182 368 0.232
response to cytokine GO:0034097 215 0.231
heart process GO:0003015 57 0.230
Zebrafish Rat
positive regulation of molecular function GO:0044093 230 0.227
Human Rat
long term synaptic potentiation GO:0060291 21 0.226
regulation of nucleotide metabolic process GO:0006140 117 0.224
Human Mouse Rat
regulation of protein transport GO:0051223 68 0.218
negative regulation of macromolecule metabolic process GO:0010605 260 0.218
regulation of protein modification process GO:0031399 194 0.218
protein secretion GO:0009306 34 0.217
establishment of protein localization GO:0045184 141 0.215
transcription from rna polymerase ii promoter GO:0006366 252 0.214
cellular chemical homeostasis GO:0055082 247 0.213
purine containing compound metabolic process GO:0072521 253 0.212
Human Mouse Rat
anatomical structure morphogenesis GO:0009653 298 0.212
regulation of hydrolase activity GO:0051336 143 0.212
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.211
positive regulation of developmental process GO:0051094 283 0.210
positive regulation of gene expression GO:0010628 244 0.209
circulatory system process GO:0003013 183 0.209
amide transport GO:0042886 105 0.209
Rat
transcription dna templated GO:0006351 377 0.207
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.202
Human Mouse Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.202
response to amphetamine GO:0001975 25 0.200
Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.198
positive regulation of phosphate metabolic process GO:0045937 262 0.198
Human Mouse Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.198
Human Mouse Rat
circulatory system development GO:0072359 134 0.196
Rat
second messenger mediated signaling GO:0019932 51 0.196
positive regulation of camp metabolic process GO:0030816 31 0.191
Human Mouse Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.190
regulation of rna biosynthetic process GO:2001141 381 0.186
regulation of immune system process GO:0002682 123 0.185
Mouse
cytosolic calcium ion homeostasis GO:0051480 140 0.185
positive regulation of long term synaptic potentiation GO:1900273 4 0.183
response to ethanol GO:0045471 162 0.183
cognition GO:0050890 92 0.181
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.180
Human Mouse Rat
cell projection organization GO:0030030 302 0.180
regulation of blood circulation GO:1903522 110 0.180
Rat
nucleotide metabolic process GO:0009117 279 0.177
Human Mouse Rat
response to corticosteroid GO:0031960 235 0.175
feeding behavior GO:0007631 53 0.174
camp metabolic process GO:0046058 63 0.174
Human Mouse Rat
leukocyte migration GO:0050900 38 0.172
gliogenesis GO:0042063 93 0.169
cellular metal ion homeostasis GO:0006875 172 0.169
positive regulation of locomotion GO:0040017 102 0.167
regulation of blood pressure GO:0008217 83 0.167
Rat
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.165
regulation of cell proliferation GO:0042127 359 0.164
nucleobase containing small molecule metabolic process GO:0055086 316 0.163
Human Mouse Rat
regulation of neurogenesis GO:0050767 247 0.162
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.162
cellular component movement GO:0006928 248 0.161
regulation of angiogenesis GO:0045765 39 0.161
Rat
cell type specific apoptotic process GO:0097285 134 0.160
cellular response to molecule of bacterial origin GO:0071219 56 0.160
learning or memory GO:0007611 90 0.160
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.158
regulation of cellular component movement GO:0051270 150 0.157
purine nucleotide metabolic process GO:0006163 229 0.157
Human Mouse Rat
organelle organization GO:0006996 266 0.156
ribose phosphate metabolic process GO:0019693 235 0.155
Human Mouse Rat
macromolecule localization GO:0033036 252 0.154
negative regulation of response to external stimulus GO:0032102 37 0.152
blood vessel development GO:0001568 69 0.152
Rat
regulation of nucleotide biosynthetic process GO:0030808 47 0.151
Human Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.150
secretion GO:0046903 307 0.149
neuron death GO:0070997 127 0.149
neuron development GO:0048666 286 0.148
excretion GO:0007588 24 0.147
positive regulation of cellular protein metabolic process GO:0032270 167 0.146
Rat
regulation of peptide transport GO:0090087 87 0.145
Rat
negative regulation of circadian sleep wake cycle non rem sleep GO:0042323 2 0.145
Rat
positive regulation of signal transduction GO:0009967 175 0.144
Mouse Rat
negative regulation of transport GO:0051051 136 0.143
Rat
negative adaptation of signaling pathway GO:0022401 10 0.142
positive regulation of camp biosynthetic process GO:0030819 28 0.142
Human Mouse Rat
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.141
Human Mouse Rat
regulation of transcription dna templated GO:0006355 374 0.141
positive regulation of neurotransmitter transport GO:0051590 9 0.139
regulation of system process GO:0044057 208 0.139
positive regulation of hydrolase activity GO:0051345 86 0.136
glycosyl compound metabolic process GO:1901657 182 0.136
regulation of synaptic transmission glutamatergic GO:0051966 26 0.135
immune response GO:0006955 104 0.135
peptide secretion GO:0002790 86 0.133
Rat
regulation of neuron death GO:1901214 115 0.133
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.132
Human Mouse Rat
purine ribonucleotide metabolic process GO:0009150 227 0.132
Human Mouse Rat
negative regulation of apoptotic process GO:0043066 181 0.130
cell migration GO:0016477 197 0.130
cell motility GO:0048870 202 0.130
cell activation GO:0001775 97 0.130
negative regulation of rna metabolic process GO:0051253 123 0.129
cardiovascular system development GO:0072358 134 0.129
Rat
cellular response to lipopolysaccharide GO:0071222 55 0.128
positive regulation of rna biosynthetic process GO:1902680 197 0.127
positive regulation of cellular biosynthetic process GO:0031328 295 0.127
Human Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.126
Human Mouse Rat
regulation of phosphorylation GO:0042325 248 0.125
negative regulation of phosphorus metabolic process GO:0010563 80 0.125
regulation of smooth muscle contraction GO:0006940 29 0.124
Rat
single organism organelle organization GO:1902589 180 0.123
angiogenesis GO:0001525 53 0.122
Rat
regulation of protein secretion GO:0050708 28 0.122
response to acid chemical GO:0001101 222 0.121
response to ketone GO:1901654 182 0.121
regulation of defense response GO:0031347 68 0.120
Mouse Rat
positive regulation of nervous system development GO:0051962 178 0.120
purine containing compound biosynthetic process GO:0072522 85 0.120
Human Mouse Rat
single organism catabolic process GO:0044712 283 0.120
Rat
intracellular transport GO:0046907 185 0.119
Rat
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.119
calcium mediated signaling GO:0019722 23 0.117
regulation of calcium ion transport GO:0051924 77 0.117
positive regulation of protein modification process GO:0031401 142 0.117
Rat
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.116
Human Mouse Rat
carbohydrate derivative catabolic process GO:1901136 147 0.116
nucleoside catabolic process GO:0009164 126 0.116
cellular response to cytokine stimulus GO:0071345 127 0.115
negative regulation of nucleic acid templated transcription GO:1903507 117 0.115
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.113
cellular response to nitrogen compound GO:1901699 210 0.112
response to extracellular stimulus GO:0009991 380 0.111
reproductive process GO:0022414 372 0.111
localization of cell GO:0051674 202 0.109
negative regulation of cellular component organization GO:0051129 83 0.108
ras protein signal transduction GO:0007265 29 0.108
regulation of protein kinase activity GO:0045859 105 0.107
positive regulation of phosphorylation GO:0042327 177 0.107
Rat
negative regulation of cell communication GO:0010648 158 0.107
Rat
positive regulation of stress activated mapk cascade GO:0032874 17 0.106
regulation of cellular catabolic process GO:0031329 101 0.106
heart contraction GO:0060047 57 0.106
Zebrafish Rat
olfactory learning GO:0008355 1 0.105
positive regulation of protein phosphorylation GO:0001934 135 0.105
Rat
regulation of protein metabolic process GO:0051246 289 0.105
myeloid leukocyte activation GO:0002274 36 0.103
protein complex subunit organization GO:0071822 302 0.100
purine nucleoside triphosphate catabolic process GO:0009146 122 0.100
catabolic process GO:0009056 351 0.098
Rat
response to temperature stimulus GO:0009266 94 0.098
Rat
positive regulation of programmed cell death GO:0043068 157 0.098
Mouse
nucleotide biosynthetic process GO:0009165 98 0.098
Human Mouse Rat
vascular process in circulatory system GO:0003018 96 0.098
positive regulation of immune system process GO:0002684 90 0.097
memory GO:0007613 54 0.096
cellular catabolic process GO:0044248 295 0.096
response to hypoxia GO:0001666 231 0.096
Rat
response to nutrient levels GO:0031667 370 0.095
positive regulation of biosynthetic process GO:0009891 319 0.095
Human Mouse Rat
regulation of cell motility GO:2000145 131 0.095
regulation of blood vessel size GO:0050880 89 0.095
negative regulation of immune system process GO:0002683 39 0.095
Mouse
locomotion GO:0040011 237 0.095
response to metal ion GO:0010038 253 0.094
renal sodium excretion GO:0035812 20 0.093
regulation of secretion GO:0051046 224 0.092
negative regulation of developmental process GO:0051093 125 0.091
small gtpase mediated signal transduction GO:0007264 36 0.091
positive regulation of protein transport GO:0051222 41 0.091
cytokine production GO:0001816 61 0.090
regulation of response to wounding GO:1903034 69 0.090
Mouse Rat
negative regulation of ion transport GO:0043271 51 0.090
Rat
purine ribonucleotide biosynthetic process GO:0009152 81 0.090
Human Mouse Rat
regulation of stress activated mapk cascade GO:0032872 23 0.090
positive regulation of cellular component organization GO:0051130 200 0.089
carbohydrate derivative biosynthetic process GO:1901137 124 0.089
Human Mouse Rat
ribonucleoside metabolic process GO:0009119 174 0.089
enzyme linked receptor protein signaling pathway GO:0007167 116 0.089
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.089
Human Mouse Rat
glial cell differentiation GO:0010001 65 0.087
anatomical structure formation involved in morphogenesis GO:0048646 83 0.087
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.087
chemical homeostasis GO:0048878 292 0.086
neuron projection development GO:0031175 273 0.086
response to purine containing compound GO:0014074 126 0.086
response to decreased oxygen levels GO:0036293 237 0.085
Rat
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.085
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 2 0.084
Human
metal ion transport GO:0030001 289 0.084
actin filament based process GO:0030029 86 0.084
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.083
regulation of leukocyte migration GO:0002685 24 0.082
regulation of cellular amine metabolic process GO:0033238 8 0.082
dephosphorylation GO:0016311 98 0.081
Rat
positive regulation of neural precursor cell proliferation GO:2000179 10 0.081
ribonucleoside catabolic process GO:0042454 126 0.081
regulation of purine nucleotide catabolic process GO:0033121 65 0.081
purine nucleoside metabolic process GO:0042278 169 0.081
regulation of respiratory system process GO:0044065 1 0.081
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.080
Rat
organophosphate biosynthetic process GO:0090407 143 0.080
Human Mouse Rat
regulation of ion transport GO:0043269 245 0.080
cellular ketone metabolic process GO:0042180 51 0.080
protein localization GO:0008104 191 0.079
peptidyl tyrosine phosphorylation GO:0018108 72 0.079
Rat
response to biotic stimulus GO:0009607 226 0.079
protein phosphorylation GO:0006468 345 0.078
ribonucleoside triphosphate metabolic process GO:0009199 141 0.078
locomotory exploration behavior GO:0035641 1 0.078
regulation of neuron projection development GO:0010975 161 0.077
taxis GO:0042330 67 0.077
cellular component assembly GO:0022607 360 0.076
regulation of neuron differentiation GO:0045664 208 0.076
gtp metabolic process GO:0046039 72 0.076
synaptic transmission glutamatergic GO:0035249 33 0.076
neurological system process GO:0050877 219 0.076
cellular response to peptide GO:1901653 133 0.075
cation transport GO:0006812 382 0.075
regulation of organic acid transport GO:0032890 35 0.075
cell part morphogenesis GO:0032990 123 0.075
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.075
developmental growth GO:0048589 100 0.075
sensory perception of pain GO:0019233 73 0.074
Rat
regulation of catalytic activity GO:0050790 304 0.074
regulation of cell projection organization GO:0031344 175 0.073
negative regulation of metabolic process GO:0009892 331 0.073
regulation of cell migration GO:0030334 128 0.073
positive regulation of neurogenesis GO:0050769 165 0.073
positive regulation of cellular component movement GO:0051272 102 0.072
response to oxidative stress GO:0006979 186 0.072
regulation of neuronal synaptic plasticity GO:0048168 31 0.072
purine nucleoside catabolic process GO:0006152 124 0.072
positive regulation of transcription dna templated GO:0045893 197 0.072
cellular lipid metabolic process GO:0044255 208 0.072
cell chemotaxis GO:0060326 31 0.071
detection of abiotic stimulus GO:0009582 13 0.071
Rat
regulation of renal sodium excretion GO:0035813 20 0.071
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.071
regulation of excretion GO:0044062 21 0.071
regulation of phosphate metabolic process GO:0019220 349 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.071
macromolecular complex subunit organization GO:0043933 339 0.071
response to inorganic substance GO:0010035 377 0.071
aging GO:0007568 241 0.071
female pregnancy GO:0007565 122 0.070
positive regulation of jnk cascade GO:0046330 13 0.070
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.070
response to lipopolysaccharide GO:0032496 191 0.068
regulation of cytokine production GO:0001817 56 0.068
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.068
Rat
response to wounding GO:0009611 254 0.068
Mouse Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.067
regulation of membrane potential GO:0042391 110 0.067
organic acid metabolic process GO:0006082 292 0.066
stress activated mapk cascade GO:0051403 35 0.066
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.066
regulation of smooth muscle cell proliferation GO:0048660 75 0.065
positive regulation of nucleic acid templated transcription GO:1903508 197 0.065
cellular component biogenesis GO:0044085 368 0.064
locomotory behavior GO:0007626 15 0.064
brain development GO:0007420 247 0.064
carboxylic acid metabolic process GO:0019752 289 0.064
regulation of catabolic process GO:0009894 113 0.064
Rat
regulation of developmental growth GO:0048638 45 0.063
oxoacid metabolic process GO:0043436 290 0.063
positive regulation of rna metabolic process GO:0051254 203 0.063
purine ribonucleoside catabolic process GO:0046130 124 0.062
positive regulation of blood circulation GO:1903524 65 0.062
Rat
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.061
Rat
positive regulation of adenylate cyclase activity GO:0045762 12 0.061
Human
carboxylic acid transport GO:0046942 115 0.061
ribonucleoside triphosphate catabolic process GO:0009203 122 0.061
purine ribonucleoside metabolic process GO:0046128 168 0.061
cyclic purine nucleotide metabolic process GO:0052652 62 0.061
Human Mouse Rat
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.061
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.061
ribonucleotide biosynthetic process GO:0009260 85 0.060
Human Mouse Rat
peptide transport GO:0015833 97 0.059
Rat
central nervous system development GO:0007417 311 0.059
regulation of anatomical structure morphogenesis GO:0022603 141 0.059
Rat
regulation of gtpase activity GO:0043087 57 0.059
monoamine transport GO:0015844 43 0.059
organic cyclic compound catabolic process GO:1901361 175 0.058
temperature homeostasis GO:0001659 17 0.058
Rat
positive regulation of map kinase activity GO:0043406 46 0.058
Rat
acute inflammatory response GO:0002526 58 0.058
Rat
multi organism reproductive process GO:0044703 262 0.058
muscle structure development GO:0061061 87 0.057
positive regulation of protein secretion GO:0050714 19 0.057
positive regulation of catabolic process GO:0009896 78 0.057
purine nucleotide catabolic process GO:0006195 136 0.057
renal system process GO:0003014 40 0.057
response to amino acid GO:0043200 75 0.057
cell cycle GO:0007049 101 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.056
synaptic transmission gabaergic GO:0051932 22 0.056
Mouse Rat
lipid metabolic process GO:0006629 283 0.055
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.055
cellular amine metabolic process GO:0044106 38 0.055
positive regulation of cell motility GO:2000147 97 0.055
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.054
Human Mouse Rat
cellular response to mechanical stimulus GO:0071260 48 0.054
neuron neuron synaptic transmission GO:0007270 60 0.054
organic anion transport GO:0015711 132 0.054
response to increased oxygen levels GO:0036296 45 0.054
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.054
Human Mouse Rat
regulation of growth GO:0040008 105 0.053
single organism cellular localization GO:1902580 102 0.053
Rat
single organism intracellular transport GO:1902582 166 0.053
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.052
blood vessel morphogenesis GO:0048514 58 0.052
Rat
positive regulation of cytokine production GO:0001819 42 0.052
actin cytoskeleton organization GO:0030036 73 0.052
regulation of establishment of protein localization GO:0070201 69 0.052
response to estrogen GO:0043627 232 0.052
nucleotide catabolic process GO:0009166 139 0.051
smooth muscle cell proliferation GO:0048659 77 0.051
positive regulation of angiogenesis GO:0045766 28 0.051
organonitrogen compound catabolic process GO:1901565 179 0.051
negative regulation of homeostatic process GO:0032845 47 0.051
Rat
positive regulation of apoptotic process GO:0043065 154 0.051
Mouse
muscle cell proliferation GO:0033002 84 0.050
positive regulation of neuron differentiation GO:0045666 126 0.050
innate immune response GO:0045087 35 0.050
growth GO:0040007 165 0.050
amine metabolic process GO:0009308 38 0.050
negative regulation of transcription dna templated GO:0045892 116 0.050
regulation of respiratory gaseous exchange GO:0043576 2 0.050
Rat
response to radiation GO:0009314 137 0.049
apoptotic signaling pathway GO:0097190 27 0.049
Mouse
cellular protein localization GO:0034613 122 0.049
Rat
peptidyl amino acid modification GO:0018193 126 0.049
Rat
positive regulation of protein kinase activity GO:0045860 73 0.048
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.048
Human Mouse Rat
regulation of heart rate GO:0002027 16 0.048
negative regulation of rna biosynthetic process GO:1902679 118 0.048
negative regulation of nervous system development GO:0051961 79 0.047
negative regulation of defense response GO:0031348 19 0.047
Mouse Rat
camp biosynthetic process GO:0006171 47 0.047
Human Mouse Rat
positive regulation of kinase activity GO:0033674 77 0.047
Rat
regulation of long term synaptic potentiation GO:1900271 5 0.047
striated muscle contraction GO:0006941 44 0.047
Rat
kidney development GO:0001822 67 0.047
regulation of map kinase activity GO:0043405 53 0.047
Rat
regulation of anatomical structure size GO:0090066 135 0.047
multicellular organism growth GO:0035264 1 0.046
visual learning GO:0008542 8 0.046
positive regulation of secretion by cell GO:1903532 128 0.046
regulation of feeding behavior GO:0060259 14 0.046
nucleoside metabolic process GO:0009116 179 0.046
immune system development GO:0002520 41 0.045
positive regulation of fever generation GO:0031622 5 0.045
positive regulation of cell death GO:0010942 184 0.045
Mouse
negative regulation of secretion by cell GO:1903531 72 0.045
Rat
regulation of tube size GO:0035150 89 0.045
glycosyl compound catabolic process GO:1901658 126 0.044
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.044
Human Mouse Rat
neurotrophin production GO:0032898 2 0.044
Rat
negative regulation of muscle contraction GO:0045932 8 0.044
Rat
regulation of chemotaxis GO:0050920 29 0.044
cellular response to lipid GO:0071396 201 0.044
single organism biosynthetic process GO:0044711 342 0.043
Human Mouse Rat
regulation of ion homeostasis GO:2000021 63 0.043
negative regulation of secretion GO:0051048 82 0.043
Rat
negative regulation of circadian rhythm GO:0042754 5 0.043
Rat
positive regulation of cyclase activity GO:0031281 15 0.043
Human
regulation of peptide secretion GO:0002791 82 0.043
Rat
regulation of response to external stimulus GO:0032101 106 0.043
regulation of synaptic transmission gabaergic GO:0032228 17 0.043
Mouse Rat
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.042
response to electrical stimulus GO:0051602 56 0.042
positive regulation of organic acid transport GO:0032892 22 0.042
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.042
Rat
cytokine mediated signaling pathway GO:0019221 43 0.042
sequestering of calcium ion GO:0051208 8 0.042
hormone secretion GO:0046879 115 0.042
Rat
negative regulation of biosynthetic process GO:0009890 168 0.042
Rat
multi multicellular organism process GO:0044706 138 0.041
muscle organ development GO:0007517 50 0.041
negative regulation of gene expression GO:0010629 199 0.041
negative regulation of phosphate metabolic process GO:0045936 80 0.040
negative regulation of defecation GO:2000293 1 0.040
regulation of cell cycle GO:0051726 73 0.040
neuron apoptotic process GO:0051402 88 0.040
cytoskeleton organization GO:0007010 111 0.040
response to carbohydrate GO:0009743 183 0.040
monovalent inorganic cation transport GO:0015672 172 0.040
Rat
neuromuscular process GO:0050905 2 0.039
interleukin 6 production GO:0032635 12 0.039
heterocycle catabolic process GO:0046700 167 0.039
reproduction GO:0000003 245 0.039
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.039
Human Mouse Rat
myeloid cell differentiation GO:0030099 22 0.039
cellular response to stress GO:0033554 269 0.038

Adora2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org