Rattus norvegicus

0 known processes

Afm

afamin

Afm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.548
organic acid metabolic process GO:0006082 292 0.463
positive regulation of multicellular organismal process GO:0051240 387 0.429
Rat
alpha amino acid metabolic process GO:1901605 71 0.353
apoptotic process GO:0006915 381 0.286
cellular component assembly GO:0022607 360 0.270
response to inorganic substance GO:0010035 377 0.261
Rat
choline transport GO:0015871 4 0.227
cellular response to oxygen containing compound GO:1901701 386 0.218
cellular response to lipid GO:0071396 201 0.218
oxoacid metabolic process GO:0043436 290 0.205
small molecule biosynthetic process GO:0044283 124 0.177
regulation of apoptotic process GO:0042981 335 0.166
organic acid biosynthetic process GO:0016053 83 0.165
response to corticosteroid GO:0031960 235 0.162
response to camp GO:0051591 91 0.158
response to metal ion GO:0010038 253 0.154
Rat
cation transport GO:0006812 382 0.150
regulation of programmed cell death GO:0043067 341 0.142
sodium independent organic anion transport GO:0043252 2 0.136
muscle contraction GO:0006936 88 0.129
response to acid chemical GO:0001101 222 0.127
positive regulation of apoptotic process GO:0043065 154 0.127
response to peptide GO:1901652 292 0.122
glutathione transport GO:0034635 2 0.116
antibiotic transport GO:0042891 2 0.113
response to biotic stimulus GO:0009607 226 0.110
programmed cell death GO:0012501 392 0.105
cellular response to endogenous stimulus GO:0071495 377 0.102
protein complex subunit organization GO:0071822 302 0.100
chemical homeostasis GO:0048878 292 0.098
response to external biotic stimulus GO:0043207 221 0.095
response to lipopolysaccharide GO:0032496 191 0.094
neurotransmitter transport GO:0006836 42 0.093
cellular amino acid metabolic process GO:0006520 107 0.093
circulatory system process GO:0003013 183 0.093
aging GO:0007568 241 0.089
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.088
response to organophosphorus GO:0046683 102 0.086
vascular process in circulatory system GO:0003018 96 0.083
oligopeptide transport GO:0006857 4 0.081
macromolecular complex subunit organization GO:0043933 339 0.081
neurological system process GO:0050877 219 0.080
response to estrogen GO:0043627 232 0.079
Rat
negative regulation of apoptotic process GO:0043066 181 0.078
metal ion transport GO:0030001 289 0.078
positive regulation of cellular component organization GO:0051130 200 0.077
response to nutrient levels GO:0031667 370 0.077
Rat
protein complex assembly GO:0006461 263 0.076
response to molecule of bacterial origin GO:0002237 194 0.076
cation transmembrane transport GO:0098655 263 0.075
cellular component biogenesis GO:0044085 368 0.073
response to decreased oxygen levels GO:0036293 237 0.073
regulation of multicellular organismal development GO:2000026 376 0.071
alpha amino acid catabolic process GO:1901606 20 0.070
benzene containing compound metabolic process GO:0042537 22 0.070
response to transition metal nanoparticle GO:1990267 122 0.069
Rat
macromolecular complex assembly GO:0065003 273 0.069
aromatic amino acid family catabolic process GO:0009074 7 0.068
response to glucocorticoid GO:0051384 223 0.067
response to nutrient GO:0007584 248 0.064
Rat
ion transmembrane transport GO:0034220 365 0.063
muscle system process GO:0003012 115 0.063
response to oxygen levels GO:0070482 265 0.059
regulation of cellular component organization GO:0051128 368 0.058
protein oligomerization GO:0051259 191 0.055
organelle organization GO:0006996 266 0.054
cellular response to alcohol GO:0097306 87 0.053
blood circulation GO:0008015 183 0.053
cellular catabolic process GO:0044248 295 0.053
linoleic acid metabolic process GO:0043651 4 0.052
regulation of protein metabolic process GO:0051246 289 0.052
positive regulation of synaptic transmission GO:0050806 62 0.052
carboxylic acid biosynthetic process GO:0046394 83 0.052
protein complex biogenesis GO:0070271 263 0.051
protein homooligomerization GO:0051260 91 0.051
response to purine containing compound GO:0014074 126 0.050
reproductive process GO:0022414 372 0.050
Rat
gland development GO:0048732 155 0.050
Rat
transmembrane transport GO:0055085 412 0.050
regulation of system process GO:0044057 208 0.049
epinephrine transport GO:0048241 7 0.048
response to bacterium GO:0009617 200 0.048
organic hydroxy compound transport GO:0015850 77 0.047
positive regulation of cell death GO:0010942 184 0.046
single organism organelle organization GO:1902589 180 0.046
regulation of rna biosynthetic process GO:2001141 381 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.045
coenzyme metabolic process GO:0006732 86 0.044
homeostatic process GO:0042592 331 0.044
regulation of calcium ion transport GO:0051924 77 0.044
indolalkylamine metabolic process GO:0006586 5 0.043
amine metabolic process GO:0009308 38 0.043
response to other organism GO:0051707 220 0.043
positive regulation of developmental process GO:0051094 283 0.043
response to ethanol GO:0045471 162 0.042
aromatic compound catabolic process GO:0019439 168 0.042
cellular response to external stimulus GO:0071496 118 0.042
female pregnancy GO:0007565 122 0.041
Rat
response to estradiol GO:0032355 164 0.041
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
cell type specific apoptotic process GO:0097285 134 0.041
reactive nitrogen species metabolic process GO:2001057 1 0.040
g protein coupled receptor signaling pathway GO:0007186 242 0.040
cellular response to hormone stimulus GO:0032870 247 0.039
cellular amine metabolic process GO:0044106 38 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
response to peptide hormone GO:0043434 278 0.039
cellular biogenic amine catabolic process GO:0042402 9 0.038
cellular modified amino acid metabolic process GO:0006575 61 0.037
single organism biosynthetic process GO:0044711 342 0.037
catabolic process GO:0009056 351 0.036
transmission of nerve impulse GO:0019226 42 0.036
negative regulation of cell death GO:0060548 229 0.035
regulation of muscle system process GO:0090257 79 0.035
long chain fatty acid metabolic process GO:0001676 32 0.035
inflammatory response GO:0006954 150 0.034
cellular response to organonitrogen compound GO:0071417 197 0.034
cell cell signaling GO:0007267 335 0.034
cellular homeostasis GO:0019725 252 0.033
cellular amino acid biosynthetic process GO:0008652 32 0.033
anion transport GO:0006820 178 0.033
liver development GO:0001889 90 0.032
Rat
negative regulation of protein metabolic process GO:0051248 114 0.032
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
reactive oxygen species biosynthetic process GO:1903409 8 0.032
cellular response to peptide hormone stimulus GO:0071375 120 0.032
modified amino acid transport GO:0072337 12 0.031
regulation of peptide transport GO:0090087 87 0.031
cellular response to organic cyclic compound GO:0071407 202 0.031
regulation of neurological system process GO:0031644 43 0.031
amide transport GO:0042886 105 0.031
carnitine transport GO:0015879 1 0.030
cellular response to nitrogen compound GO:1901699 210 0.030
tripeptide transport GO:0042939 2 0.030
sulfur compound transport GO:0072348 8 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.029
single organism catabolic process GO:0044712 283 0.029
growth GO:0040007 165 0.029
response to hypoxia GO:0001666 231 0.028
nitrogen compound transport GO:0071705 229 0.028
regulation of cell growth GO:0001558 85 0.028
response to glucose GO:0009749 136 0.028
vitamin transport GO:0051180 14 0.028
Human
regulation of hydrolase activity GO:0051336 143 0.028
cellular amino acid catabolic process GO:0009063 21 0.028
regulation of cell projection organization GO:0031344 175 0.027
defecation GO:0030421 1 0.027
cytoskeleton organization GO:0007010 111 0.027
serine family amino acid metabolic process GO:0009069 12 0.027
sulfur compound metabolic process GO:0006790 70 0.027
negative regulation of calcium ion import GO:0090281 2 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
response to toxic substance GO:0009636 133 0.027
catecholamine transport GO:0051937 37 0.027
response to vitamin GO:0033273 131 0.026
positive regulation of hydrolase activity GO:0051345 86 0.026
cellular response to peptide GO:1901653 133 0.026
response to monosaccharide GO:0034284 159 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
regulation of neurotransmitter levels GO:0001505 42 0.026
response to hexose GO:0009746 144 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.026
protein processing GO:0016485 68 0.026
monocarboxylic acid metabolic process GO:0032787 152 0.026
multi multicellular organism process GO:0044706 138 0.026
Rat
regulation of defecation GO:2000292 1 0.026
regulation of cell differentiation GO:0045595 320 0.025
blood vessel morphogenesis GO:0048514 58 0.025
regulation of homeostatic process GO:0032844 101 0.025
heterocycle catabolic process GO:0046700 167 0.025
response to molecule of fungal origin GO:0002238 3 0.025
divalent metal ion transport GO:0070838 132 0.025
amine catabolic process GO:0009310 9 0.024
plasminogen activation GO:0031639 2 0.024
response to extracellular stimulus GO:0009991 380 0.024
Rat
hepaticobiliary system development GO:0061008 90 0.023
Rat
epithelium development GO:0060429 96 0.023
negative regulation of molecular function GO:0044092 133 0.023
cellular ketone metabolic process GO:0042180 51 0.023
angiogenesis GO:0001525 53 0.023
response to lead ion GO:0010288 33 0.023
catecholamine secretion GO:0050432 33 0.023
divalent inorganic cation transport GO:0072511 134 0.023
positive regulation of serotonin secretion GO:0014064 1 0.023
regulation of hormone levels GO:0010817 187 0.022
neutral lipid metabolic process GO:0006638 21 0.022
tissue development GO:0009888 252 0.022
developmental process involved in reproduction GO:0003006 159 0.022
acetate ester transport GO:1901374 7 0.022
reproduction GO:0000003 245 0.021
cellular chemical homeostasis GO:0055082 247 0.021
nuclear transport GO:0051169 49 0.021
signal release GO:0023061 145 0.021
cofactor metabolic process GO:0051186 95 0.021
insecticide metabolic process GO:0017143 4 0.021
cellular response to stress GO:0033554 269 0.021
peptide transport GO:0015833 97 0.021
regulation of extracellular matrix constituent secretion GO:0003330 2 0.021
regulation of excretion GO:0044062 21 0.021
thioester metabolic process GO:0035383 28 0.021
cellular response to corticosteroid stimulus GO:0071384 69 0.021
quaternary ammonium group transport GO:0015697 6 0.021
single organism reproductive process GO:0044702 297 0.021
regulation of protein maturation GO:1903317 50 0.021
negative regulation of metabolic process GO:0009892 331 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
intracellular signal transduction GO:0035556 314 0.020
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
regulation of serine type endopeptidase activity GO:1900003 1 0.020
regulation of synaptic plasticity GO:0048167 70 0.020
behavior GO:0007610 205 0.020
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
glycine metabolic process GO:0006544 7 0.020
negative regulation of serine type peptidase activity GO:1902572 1 0.020
proteolysis GO:0006508 175 0.020
response to fungus GO:0009620 8 0.019
fluorene metabolic process GO:0018917 1 0.019
monocarboxylic acid transport GO:0015718 52 0.019
multi organism reproductive process GO:0044703 262 0.019
Rat
regulation of catalytic activity GO:0050790 304 0.019
cytokine production GO:0001816 61 0.019
telencephalon development GO:0021537 62 0.019
protein maturation GO:0051604 68 0.019
response to activity GO:0014823 73 0.019
response to testosterone GO:0033574 55 0.019
small molecule catabolic process GO:0044282 59 0.018
sensory perception GO:0007600 101 0.018
regulation of molecular function GO:0065009 398 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
calcium ion transport GO:0006816 131 0.018
monoamine transport GO:0015844 43 0.018
organophosphate metabolic process GO:0019637 370 0.018
cellular sodium ion homeostasis GO:0006883 4 0.018
pyridine containing compound metabolic process GO:0072524 32 0.018
regulation of proteolysis GO:0030162 66 0.018
defense response GO:0006952 194 0.018
rna biosynthetic process GO:0032774 380 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
smooth muscle contraction GO:0006939 37 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
serine family amino acid biosynthetic process GO:0009070 4 0.018
response to mercury ion GO:0046689 15 0.018
Rat
response to vitamin b6 GO:0034516 1 0.018
tonic smooth muscle contraction GO:0014820 4 0.018
positive regulation of neuron differentiation GO:0045666 126 0.017
drug metabolic process GO:0017144 11 0.017
carbohydrate homeostasis GO:0033500 75 0.017
response to xenobiotic stimulus GO:0009410 23 0.017
carboxylic acid transport GO:0046942 115 0.017
negative regulation of response to external stimulus GO:0032102 37 0.017
regulation of neurogenesis GO:0050767 247 0.017
regulation of cellular localization GO:0060341 263 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
regulation of metal ion transport GO:0010959 118 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
regulation of transcription dna templated GO:0006355 374 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
blood vessel development GO:0001568 69 0.017
positive regulation of cytokine production GO:0001819 42 0.017
organic anion transport GO:0015711 132 0.017
peptide secretion GO:0002790 86 0.017
actin filament based process GO:0030029 86 0.017
positive regulation of nervous system development GO:0051962 178 0.017
central nervous system development GO:0007417 311 0.017
regulation of nervous system development GO:0051960 264 0.017
glycerolipid metabolic process GO:0046486 67 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
regulation of peptidase activity GO:0052547 55 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
tryptophan metabolic process GO:0006568 5 0.016
forebrain development GO:0030900 98 0.016
cognition GO:0050890 92 0.016
tryptophan catabolic process GO:0006569 5 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
organic substance catabolic process GO:1901575 316 0.016
nucleoside metabolic process GO:0009116 179 0.016
fatty acid metabolic process GO:0006631 99 0.016
negative regulation of transport GO:0051051 136 0.016
protein homotrimerization GO:0070207 15 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
regulation of ion homeostasis GO:2000021 63 0.016
response to triglyceride GO:0034014 3 0.016
sensory perception of pain GO:0019233 73 0.016
negative regulation of chronic inflammatory response GO:0002677 2 0.016
regulation of response to wounding GO:1903034 69 0.016
developmental growth GO:0048589 100 0.015
memory GO:0007613 54 0.015
regulation of norepinephrine secretion GO:0014061 15 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
beta alanine metabolic process GO:0019482 3 0.015
amino acid transmembrane transport GO:0003333 33 0.015
multicellular organism growth GO:0035264 1 0.015
heart contraction GO:0060047 57 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
rna metabolic process GO:0016070 406 0.015
fatty acid derivative metabolic process GO:1901568 38 0.015
steroid metabolic process GO:0008202 73 0.015
neuron death GO:0070997 127 0.014
negative regulation of serine type endopeptidase activity GO:1900004 1 0.014
response to radiation GO:0009314 137 0.014
lateral ventricle development GO:0021670 1 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
amine transport GO:0015837 57 0.014
hepatocyte proliferation GO:0072574 3 0.014
cellular response to xenobiotic stimulus GO:0071466 19 0.014
toxin transport GO:1901998 3 0.014
positive regulation of blood pressure GO:0045777 31 0.014
positive regulation of cellular component biogenesis GO:0044089 55 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
exogenous drug catabolic process GO:0042738 1 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
Rat
response to ketone GO:1901654 182 0.014
urea cycle GO:0000050 5 0.014
cardiovascular system development GO:0072358 134 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
indolalkylamine catabolic process GO:0046218 5 0.014
nicotine metabolic process GO:0018933 1 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
cellular response to acid chemical GO:0071229 75 0.013
negative regulation of luteinizing hormone secretion GO:0033685 4 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of growth GO:0040008 105 0.013
regulation of cell development GO:0060284 263 0.013
cellular response to camp GO:0071320 26 0.013
nicotinamide nucleotide metabolic process GO:0046496 28 0.013
response to heat GO:0009408 60 0.013
striated muscle tissue development GO:0014706 58 0.013
neuron differentiation GO:0030182 368 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to corticosterone GO:0051412 40 0.013
triglyceride metabolic process GO:0006641 21 0.013
response to interferon gamma GO:0034341 20 0.013
negative regulation of protein processing GO:0010955 47 0.013
regulation of tube size GO:0035150 89 0.013
response to fatty acid GO:0070542 65 0.013
amino acid betaine transport GO:0015838 1 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
alcohol metabolic process GO:0006066 77 0.013
positive regulation of extracellular matrix organization GO:1903055 4 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
peptide hormone secretion GO:0030072 84 0.013
spermatogenesis GO:0007283 99 0.013
response to cytokine GO:0034097 215 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
cation homeostasis GO:0055080 195 0.013
response to oxidative stress GO:0006979 186 0.012
regulation of protein processing GO:0070613 50 0.012
negative regulation of response to wounding GO:1903035 23 0.012
nucleotide metabolic process GO:0009117 279 0.012
protein localization to organelle GO:0033365 57 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
excretion GO:0007588 24 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of amino acid transport GO:0051955 25 0.012
negative regulation of ion transport GO:0043271 51 0.012
xenobiotic metabolic process GO:0006805 19 0.012
purine containing compound metabolic process GO:0072521 253 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
norepinephrine transport GO:0015874 18 0.012
acetyl coa metabolic process GO:0006084 17 0.012
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.012
negative regulation of protein maturation GO:1903318 47 0.012
regulation of peptide secretion GO:0002791 82 0.012
response to calcium ion GO:0051592 59 0.012
chlorinated hydrocarbon metabolic process GO:0042196 4 0.012
cellular biogenic amine metabolic process GO:0006576 30 0.012
multicellular organismal signaling GO:0035637 44 0.012
negative regulation of developmental process GO:0051093 125 0.012
bile acid and bile salt transport GO:0015721 12 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of renal sodium excretion GO:0035813 20 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
drug catabolic process GO:0042737 1 0.012
coagulation GO:0050817 28 0.012
vasculature development GO:0001944 70 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
epoxygenase p450 pathway GO:0019373 1 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.011
gliogenesis GO:0042063 93 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
lymphocyte homeostasis GO:0002260 2 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
cellular lipid metabolic process GO:0044255 208 0.011
immune response GO:0006955 104 0.011
cofactor biosynthetic process GO:0051188 28 0.011
response to mineralocorticoid GO:0051385 49 0.011
mesoderm development GO:0007498 2 0.011
regulation of membrane potential GO:0042391 110 0.011
regulation of synaptic transmission GO:0050804 141 0.011
synaptic transmission GO:0007268 235 0.011
serine family amino acid catabolic process GO:0009071 3 0.011
molting cycle process GO:0022404 2 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
response to temperature stimulus GO:0009266 94 0.011
unsaturated fatty acid metabolic process GO:0033559 39 0.011
protein phosphorylation GO:0006468 345 0.011
multicellular organism reproduction GO:0032504 233 0.011
response to sulfur dioxide GO:0010477 3 0.011
phenylpropanoid catabolic process GO:0046271 3 0.011
positive regulation of blood circulation GO:1903524 65 0.011
negative regulation of peptidase activity GO:0010466 38 0.011
response to insulin GO:0032868 133 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
response to carbohydrate GO:0009743 183 0.011
t cell migration GO:0072678 2 0.011
response to ddt GO:0046680 1 0.011
folic acid containing compound metabolic process GO:0006760 10 0.011
response to alkaloid GO:0043279 132 0.011
extracellular matrix constituent secretion GO:0070278 4 0.011
organelle localization GO:0051640 55 0.011
collagen metabolic process GO:0032963 21 0.011
nucleocytoplasmic transport GO:0006913 48 0.011
sterol homeostasis GO:0055092 3 0.010
regulation of neuron differentiation GO:0045664 208 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
hormone transport GO:0009914 121 0.010
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.010
head development GO:0060322 247 0.010
regulation of anatomical structure size GO:0090066 135 0.010
muscle cell differentiation GO:0042692 52 0.010
regulation of cell proliferation GO:0042127 359 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
regulation of response to external stimulus GO:0032101 106 0.010
naphthalene containing compound metabolic process GO:0090420 2 0.010
blood coagulation GO:0007596 26 0.010

Afm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.025
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.022
vascular disease DOID:178 0 0.020
connective tissue disease DOID:65 0 0.018
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010
artery disease DOID:0050828 0 0.010