Rattus norvegicus

112 known processes

Agap2

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

(Aliases: Pike,Centg1)

Agap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutamate receptor signaling pathway GO:0007215 43 0.821
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.435
regulation of signal transduction GO:0009966 318 0.305
ion transmembrane transport GO:0034220 365 0.198
intracellular signal transduction GO:0035556 314 0.139
g protein coupled receptor signaling pathway GO:0007186 242 0.136
Rat
positive regulation of signaling GO:0023056 270 0.133
regulation of receptor recycling GO:0001919 6 0.122
response to fungicide GO:0060992 20 0.113
catabolic process GO:0009056 351 0.099
Human Rat Fly
regulation of rna biosynthetic process GO:2001141 381 0.093
Mouse
secretion GO:0046903 307 0.092
transmembrane transport GO:0055085 412 0.090
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.087
cell cell signaling GO:0007267 335 0.079
positive regulation of cell communication GO:0010647 271 0.076
regulation of phosphorus metabolic process GO:0051174 349 0.073
response to alkaloid GO:0043279 132 0.069
neuron projection development GO:0031175 273 0.067
response to metal ion GO:0010038 253 0.063
protein phosphorylation GO:0006468 345 0.063
negative regulation of signaling GO:0023057 157 0.061
macromolecule localization GO:0033036 252 0.060
regulation of neuron projection development GO:0010975 161 0.055
protein localization GO:0008104 191 0.055
regulation of cellular protein metabolic process GO:0032268 267 0.054
neuron projection morphogenesis GO:0048812 122 0.054
aromatic compound catabolic process GO:0019439 168 0.053
Rat Fly
response to peptide GO:1901652 292 0.052
regulation of phosphate metabolic process GO:0019220 349 0.050
positive regulation of phosphorus metabolic process GO:0010562 262 0.049
cellular catabolic process GO:0044248 295 0.048
Rat Fly
response to ammonium ion GO:0060359 71 0.047
regulation of secretion GO:0051046 224 0.047
positive regulation of signal transduction GO:0009967 175 0.047
organic substance catabolic process GO:1901575 316 0.046
Human Rat Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.045
Mouse
regulation of phosphorylation GO:0042325 248 0.045
neuron development GO:0048666 286 0.044
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.043
tissue development GO:0009888 252 0.042
Mouse
ras protein signal transduction GO:0007265 29 0.042
negative regulation of signal transduction GO:0009968 83 0.040
axon development GO:0061564 96 0.040
regulation of purine nucleotide metabolic process GO:1900542 115 0.040
Rat Fly
locomotion GO:0040011 237 0.039
small gtpase mediated signal transduction GO:0007264 36 0.039
mapk cascade GO:0000165 140 0.038
regulation of cellular component organization GO:0051128 368 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
Rat Fly
response to amine GO:0014075 46 0.037
response to organophosphorus GO:0046683 102 0.036
regulation of neuron differentiation GO:0045664 208 0.036
regulation of protein metabolic process GO:0051246 289 0.036
single organism intracellular transport GO:1902582 166 0.036
regulation of neurogenesis GO:0050767 247 0.035
regulation of mapk cascade GO:0043408 116 0.035
cellular component movement GO:0006928 248 0.035
regulation of catalytic activity GO:0050790 304 0.035
regulation of rna metabolic process GO:0051252 391 0.034
Mouse
neuron differentiation GO:0030182 368 0.033
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.033
purine nucleoside catabolic process GO:0006152 124 0.033
Rat Fly
organophosphate metabolic process GO:0019637 370 0.033
Rat Fly
establishment of protein localization GO:0045184 141 0.033
calcium ion transport GO:0006816 131 0.032
purine containing compound catabolic process GO:0072523 138 0.032
Rat Fly
signal transduction by phosphorylation GO:0023014 144 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
Rat Fly
lipid metabolic process GO:0006629 283 0.031
synaptic transmission GO:0007268 235 0.031
regulation of apoptotic process GO:0042981 335 0.031
cation transmembrane transport GO:0098655 263 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
Rat Fly
regulation of purine nucleotide catabolic process GO:0033121 65 0.030
Rat Fly
regulation of secretion by cell GO:1903530 208 0.030
cellular nitrogen compound catabolic process GO:0044270 163 0.030
Rat Fly
secretion by cell GO:0032940 248 0.030
regulation of nervous system development GO:0051960 264 0.029
glycosyl compound catabolic process GO:1901658 126 0.029
Rat Fly
negative regulation of metabolic process GO:0009892 331 0.029
Human
positive regulation of neuron projection development GO:0010976 99 0.029
response to acid chemical GO:0001101 222 0.029
ribonucleotide metabolic process GO:0009259 231 0.028
Rat Fly
regulation of cell development GO:0060284 263 0.028
dephosphorylation GO:0016311 98 0.028
cellular ketone metabolic process GO:0042180 51 0.026
ribonucleotide catabolic process GO:0009261 136 0.026
Rat Fly
regulation of postsynaptic membrane potential GO:0060078 25 0.026
homeostatic process GO:0042592 331 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
Rat Fly
regulation of glutamate receptor signaling pathway GO:1900449 17 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
response to growth factor GO:0070848 189 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
Rat Fly
defecation GO:0030421 1 0.025
chemical homeostasis GO:0048878 292 0.025
calcium mediated signaling GO:0019722 23 0.025
second messenger mediated signaling GO:0019932 51 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.024
response to peptide hormone GO:0043434 278 0.024
organophosphate catabolic process GO:0046434 148 0.024
Rat Fly
organic cyclic compound catabolic process GO:1901361 175 0.024
Rat Fly
nucleoside phosphate metabolic process GO:0006753 283 0.024
Rat Fly
regulation of nucleotide metabolic process GO:0006140 117 0.023
Rat Fly
behavior GO:0007610 205 0.023
regulation of protein modification process GO:0031399 194 0.023
positive regulation of developmental process GO:0051094 283 0.023
Mouse
nitrogen compound transport GO:0071705 229 0.023
positive regulation of molecular function GO:0044093 230 0.023
neuromuscular process GO:0050905 2 0.023
response to inorganic substance GO:0010035 377 0.023
protein complex assembly GO:0006461 263 0.023
organic acid transport GO:0015849 116 0.023
intracellular transport GO:0046907 185 0.022
nucleotide catabolic process GO:0009166 139 0.022
Rat Fly
positive regulation of multicellular organismal process GO:0051240 387 0.022
Mouse
organophosphate biosynthetic process GO:0090407 143 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
Rat Fly
gtp metabolic process GO:0046039 72 0.022
Rat Fly
regulation of ion transport GO:0043269 245 0.021
adult locomotory behavior GO:0008344 4 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
amine metabolic process GO:0009308 38 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
purine containing compound metabolic process GO:0072521 253 0.021
Rat Fly
sex differentiation GO:0007548 113 0.020
cell projection organization GO:0030030 302 0.020
organ formation GO:0048645 3 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
receptor recycling GO:0001881 6 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
Rat Fly
motor neuron axon guidance GO:0008045 1 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
Rat Fly
positive regulation of gtp catabolic process GO:0033126 48 0.020
Rat Fly
negative regulation of cell communication GO:0010648 158 0.020
nucleic acid templated transcription GO:0097659 379 0.020
Mouse
heterocycle catabolic process GO:0046700 167 0.020
Rat Fly
positive regulation of nervous system development GO:0051962 178 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
Rat Fly
response to carbohydrate GO:0009743 183 0.019
regulation of membrane potential GO:0042391 110 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
chemotaxis GO:0006935 66 0.019
regulation of molecular function GO:0065009 398 0.019
regulation of ion transmembrane transporter activity GO:0032412 48 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
Rat Fly
negative regulation of transport GO:0051051 136 0.019
cellular amine metabolic process GO:0044106 38 0.019
cellular response to stress GO:0033554 269 0.018
macromolecular complex assembly GO:0065003 273 0.018
carboxylic acid transport GO:0046942 115 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
Rat Fly
single organism behavior GO:0044708 130 0.018
regulation of receptor activity GO:0010469 29 0.018
regulation of cell projection organization GO:0031344 175 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
Rat Fly
response to nicotine GO:0035094 51 0.018
vesicle mediated transport GO:0016192 181 0.018
multicellular organismal homeostasis GO:0048871 49 0.018
positive regulation of ion transport GO:0043270 94 0.018
nucleoside metabolic process GO:0009116 179 0.017
Rat Fly
regulation of transporter activity GO:0032409 50 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
Rat Fly
reproduction GO:0000003 245 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
Rat Fly
nucleoside catabolic process GO:0009164 126 0.017
Rat Fly
single organism biosynthetic process GO:0044711 342 0.017
protein transport GO:0015031 132 0.017
regulation of erk1 and erk2 cascade GO:0070372 41 0.017
oxoacid metabolic process GO:0043436 290 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
Rat Fly
synaptic vesicle exocytosis GO:0016079 15 0.016
potassium ion transport GO:0006813 97 0.016
single organism reproductive process GO:0044702 297 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
cellular protein localization GO:0034613 122 0.016
regulation of metal ion transport GO:0010959 118 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
Mouse
positive regulation of cell development GO:0010720 176 0.016
protein oligomerization GO:0051259 191 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
Rat Fly
carboxylic acid metabolic process GO:0019752 289 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
Rat Fly
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
Rat Fly
positive regulation of amine transport GO:0051954 26 0.016
regulation of anatomical structure size GO:0090066 135 0.016
organic acid metabolic process GO:0006082 292 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cell projection morphogenesis GO:0048858 123 0.015
regulation of hydrolase activity GO:0051336 143 0.015
Rat Fly
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
Rat Fly
protein heterooligomerization GO:0051291 89 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
Rat Fly
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.015
nucleotide metabolic process GO:0009117 279 0.015
Rat Fly
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
regulation of gtpase activity GO:0043087 57 0.015
Rat Fly
cellular ion homeostasis GO:0006873 184 0.015
cell type specific apoptotic process GO:0097285 134 0.014
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.014
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
Human
regulation of nucleoside metabolic process GO:0009118 66 0.014
Rat Fly
regeneration GO:0031099 163 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
divalent metal ion transport GO:0070838 132 0.014
axonogenesis GO:0007409 71 0.014
response to hydrogen peroxide GO:0042542 89 0.014
response to cocaine GO:0042220 39 0.014
response to ketone GO:1901654 182 0.014
lipid biosynthetic process GO:0008610 128 0.014
regulation of catabolic process GO:0009894 113 0.014
Human Rat Fly
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.014
cytoplasmic transport GO:0016482 115 0.014
response to amino acid GO:0043200 75 0.014
regulation of transmembrane transport GO:0034762 122 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
Rat Fly
cellular component biogenesis GO:0044085 368 0.014
membrane organization GO:0061024 94 0.014
neurological system process GO:0050877 219 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular response to peptide GO:1901653 133 0.014
amino acid transport GO:0006865 70 0.014
regulation of transcription dna templated GO:0006355 374 0.014
Mouse
regulation of transmembrane transporter activity GO:0022898 49 0.014
phospholipid metabolic process GO:0006644 61 0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.013
Rat Fly
glycerolipid metabolic process GO:0046486 67 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
peptide secretion GO:0002790 86 0.013
activation of mapkkk activity GO:0000185 1 0.013
organ induction GO:0001759 1 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
Rat Fly
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 10 0.013
organelle organization GO:0006996 266 0.013
single organism membrane organization GO:0044802 74 0.013
anion transport GO:0006820 178 0.013
response to reactive oxygen species GO:0000302 120 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
Rat Fly
purine nucleotide biosynthetic process GO:0006164 83 0.013
aging GO:0007568 241 0.013
reproductive process GO:0022414 372 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
receptor internalization GO:0031623 14 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
Rat Fly
positive regulation of long term synaptic potentiation GO:1900273 4 0.013
male sex differentiation GO:0046661 64 0.013
response to electrical stimulus GO:0051602 56 0.013
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.013
positive regulation of secretion GO:0051047 140 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
response to calcium ion GO:0051592 59 0.012
hormone secretion GO:0046879 115 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
protein complex biogenesis GO:0070271 263 0.012
metal ion transport GO:0030001 289 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
cation transport GO:0006812 382 0.012
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
protein complex subunit organization GO:0071822 302 0.012
regulation of synaptic transmission glutamatergic GO:0051966 26 0.012
metal ion homeostasis GO:0055065 186 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
sequestering of metal ion GO:0051238 9 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
Rat Fly
regulation of insulin secretion GO:0050796 65 0.012
regulation of neurotransmitter levels GO:0001505 42 0.012
regulation of response to stress GO:0080134 126 0.012
memory GO:0007613 54 0.012
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
neural crest cell development GO:0014032 2 0.012
regulation of system process GO:0044057 208 0.011
sexual reproduction GO:0019953 148 0.011
regulation of homeostatic process GO:0032844 101 0.011
cell motility GO:0048870 202 0.011
detection of stimulus GO:0051606 24 0.011
gastrulation GO:0007369 2 0.011
response to radiation GO:0009314 137 0.011
response to nutrient levels GO:0031667 370 0.011
regulation of locomotion GO:0040012 148 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of ras gtpase activity GO:0032318 32 0.011
liver development GO:0001889 90 0.011
programmed cell death GO:0012501 392 0.011
salivary gland development GO:0007431 3 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
exocytosis GO:0006887 60 0.011
signal release GO:0023061 145 0.011
l glutamate import GO:0051938 2 0.011
positive regulation of synaptic vesicle transport GO:1902805 3 0.011
actin mediated cell contraction GO:0070252 12 0.011
response to fatty acid GO:0070542 65 0.011
muscle organ morphogenesis GO:0048644 1 0.011
retinal ganglion cell axon guidance GO:0031290 1 0.011
ion homeostasis GO:0050801 212 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
Rat Fly
dicarboxylic acid transport GO:0006835 34 0.011
cerebellar cortex formation GO:0021697 2 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
establishment of organelle localization GO:0051656 37 0.010
endocytosis GO:0006897 84 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
sensory perception of bitter taste GO:0050913 4 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
sequestering of calcium ion GO:0051208 8 0.010

Agap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.022
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.021
connective tissue disease DOID:65 0 0.015