Rattus norvegicus

169 known processes

Aif1

allograft inflammatory factor 1

(Aliases: iba1,mrf-1,Bart1)

Aif1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of immunoglobulin production GO:0002637 4 0.608
negative regulation of immune system process GO:0002683 39 0.503
immune system process GO:0002376 204 0.446
regulation of immune system process GO:0002682 123 0.416
Human
negative regulation of innate immune response GO:0045824 4 0.333
neuron apoptotic process GO:0051402 88 0.290
defense response GO:0006952 194 0.285
positive regulation of multicellular organismal process GO:0051240 387 0.267
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 1 0.221
inflammatory cell apoptotic process GO:0006925 5 0.218
myeloid cell apoptotic process GO:0033028 6 0.199
neutrophil apoptotic process GO:0001781 4 0.189
cation homeostasis GO:0055080 195 0.165
homeostatic process GO:0042592 331 0.147
regulation of cellular component organization GO:0051128 368 0.135
macromolecular complex assembly GO:0065003 273 0.134
Human
cellular response to hormone stimulus GO:0032870 247 0.134
immune effector process GO:0002252 53 0.134
positive regulation of interleukin 1 beta production GO:0032731 6 0.133
immune response GO:0006955 104 0.132
cellular response to peptide GO:1901653 133 0.131
cellular response to external stimulus GO:0071496 118 0.130
leukocyte homeostasis GO:0001776 7 0.130
positive regulation of cell motility GO:2000147 97 0.128
negative regulation of neutrophil apoptotic process GO:0033030 3 0.125
carboxylic acid metabolic process GO:0019752 289 0.124
protein complex subunit organization GO:0071822 302 0.124
Human Mouse
negative regulation of cell death GO:0060548 229 0.116
neurological system process GO:0050877 219 0.112
regulation of mononuclear cell proliferation GO:0032944 26 0.110
Human
cellular response to interferon gamma GO:0071346 14 0.110
regulation of adaptive immune response GO:0002819 8 0.109
cellular metal ion homeostasis GO:0006875 172 0.108
cellular response to endogenous stimulus GO:0071495 377 0.108
calcium ion homeostasis GO:0055074 162 0.107
nucleobase containing small molecule metabolic process GO:0055086 316 0.106
aromatic compound catabolic process GO:0019439 168 0.100
oxoacid metabolic process GO:0043436 290 0.099
nucleobase containing compound catabolic process GO:0034655 152 0.097
defense response to other organism GO:0098542 17 0.095
organic acid metabolic process GO:0006082 292 0.095
regulation of defense response GO:0031347 68 0.095
negative regulation of homeostatic process GO:0032845 47 0.089
leukocyte activation GO:0045321 76 0.083
Human
carboxylic acid biosynthetic process GO:0046394 83 0.082
antigen processing and presentation of peptide antigen GO:0048002 2 0.081
cell part morphogenesis GO:0032990 123 0.080
purine nucleotide metabolic process GO:0006163 229 0.079
nucleoside phosphate metabolic process GO:0006753 283 0.078
regulation of b cell mediated immunity GO:0002712 2 0.078
metal ion homeostasis GO:0055065 186 0.077
positive regulation of cell proliferation GO:0008284 249 0.076
neuron development GO:0048666 286 0.076
neuron differentiation GO:0030182 368 0.076
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.074
protein transport GO:0015031 132 0.073
regulation of homeostatic process GO:0032844 101 0.072
t cell proliferation GO:0042098 19 0.072
Human
response to glucocorticoid GO:0051384 223 0.071
negative regulation of response to stimulus GO:0048585 155 0.069
Human
brain development GO:0007420 247 0.069
regulation of programmed cell death GO:0043067 341 0.068
response to ionizing radiation GO:0010212 59 0.068
cellular component movement GO:0006928 248 0.067
negative regulation of phosphorus metabolic process GO:0010563 80 0.066
organonitrogen compound catabolic process GO:1901565 179 0.064
g protein coupled receptor signaling pathway GO:0007186 242 0.064
ion homeostasis GO:0050801 212 0.063
regulation of leukocyte proliferation GO:0070663 26 0.062
Human
negative regulation of metabolic process GO:0009892 331 0.061
cellular response to molecule of bacterial origin GO:0071219 56 0.060
regulation of system process GO:0044057 208 0.060
immune system development GO:0002520 41 0.059
chemical homeostasis GO:0048878 292 0.059
locomotion GO:0040011 237 0.059
response to bacterium GO:0009617 200 0.059
cellular response to lipopolysaccharide GO:0071222 55 0.058
ribonucleoside metabolic process GO:0009119 174 0.058
regulation of immunoglobulin mediated immune response GO:0002889 2 0.057
regulation of response to external stimulus GO:0032101 106 0.057
Human
negative regulation of leukocyte proliferation GO:0070664 6 0.056
nucleotide metabolic process GO:0009117 279 0.055
response to inorganic substance GO:0010035 377 0.055
positive regulation of secretion GO:0051047 140 0.055
negative regulation of programmed cell death GO:0043069 183 0.055
cell migration GO:0016477 197 0.054
regulation of interleukin 1 beta secretion GO:0050706 3 0.053
response to peptide GO:1901652 292 0.053
organophosphate catabolic process GO:0046434 148 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
head development GO:0060322 247 0.052
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 1 0.052
negative regulation of protein phosphorylation GO:0001933 44 0.052
regulation of response to stress GO:0080134 126 0.052
protein complex assembly GO:0006461 263 0.052
Human
response to hexose GO:0009746 144 0.050
neuron projection development GO:0031175 273 0.050
reproduction GO:0000003 245 0.050
programmed cell death GO:0012501 392 0.049
cellular response to nitrogen compound GO:1901699 210 0.049
response to mechanical stimulus GO:0009612 134 0.049
response to external biotic stimulus GO:0043207 221 0.049
cellular calcium ion homeostasis GO:0006874 160 0.049
sequestering of calcium ion GO:0051208 8 0.049
response to organophosphorus GO:0046683 102 0.048
protein phosphorylation GO:0006468 345 0.048
regulation of cell activation GO:0050865 50 0.048
Human
response to corticosteroid GO:0031960 235 0.047
nucleoside catabolic process GO:0009164 126 0.047
positive regulation of interleukin 1 production GO:0032732 9 0.047
organic acid biosynthetic process GO:0016053 83 0.047
catabolic process GO:0009056 351 0.047
regulation of immune response GO:0050776 55 0.047
neuron death GO:0070997 127 0.047
response to metal ion GO:0010038 253 0.046
camp metabolic process GO:0046058 63 0.046
cell motility GO:0048870 202 0.046
cellular response to organonitrogen compound GO:0071417 197 0.046
anatomical structure morphogenesis GO:0009653 298 0.046
response to virus GO:0009615 17 0.046
regulation of cellular amine metabolic process GO:0033238 8 0.046
ribose phosphate metabolic process GO:0019693 235 0.045
signal release GO:0023061 145 0.045
response to radiation GO:0009314 137 0.044
central nervous system development GO:0007417 311 0.044
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.043
cellular response to peptide hormone stimulus GO:0071375 120 0.043
cell activation GO:0001775 97 0.043
Human
dna metabolic process GO:0006259 96 0.043
cellular response to lipid GO:0071396 201 0.043
response to estradiol GO:0032355 164 0.042
regulation of t cell activation GO:0050863 23 0.042
Human
macromolecule localization GO:0033036 252 0.042
cellular ketone metabolic process GO:0042180 51 0.042
b cell mediated immunity GO:0019724 4 0.042
vesicle mediated transport GO:0016192 181 0.042
Mouse
positive regulation of programmed cell death GO:0043068 157 0.042
t cell activation GO:0042110 29 0.042
Human
immunoglobulin mediated immune response GO:0016064 4 0.042
nucleoside metabolic process GO:0009116 179 0.041
regulation of cell proliferation GO:0042127 359 0.041
cellular amino acid metabolic process GO:0006520 107 0.041
blood circulation GO:0008015 183 0.041
cellular chemical homeostasis GO:0055082 247 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
regulation of immune effector process GO:0002697 32 0.041
regulation of anatomical structure morphogenesis GO:0022603 141 0.040
single organism intracellular transport GO:1902582 166 0.040
regulation of lymphocyte proliferation GO:0050670 26 0.040
Human
t cell mediated cytotoxicity GO:0001913 5 0.040
cellular response to biotic stimulus GO:0071216 59 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.040
protein complex biogenesis GO:0070271 263 0.040
Human
cellular amine metabolic process GO:0044106 38 0.040
response to temperature stimulus GO:0009266 94 0.040
cellular homeostasis GO:0019725 252 0.039
response to ketone GO:1901654 182 0.039
positive regulation of immune effector process GO:0002699 19 0.039
innate immune response GO:0045087 35 0.039
regulation of kinase activity GO:0043549 117 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.039
nitrogen compound transport GO:0071705 229 0.038
secretion by cell GO:0032940 248 0.038
ribonucleotide catabolic process GO:0009261 136 0.038
amine metabolic process GO:0009308 38 0.038
positive regulation of locomotion GO:0040017 102 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
cellular ion homeostasis GO:0006873 184 0.038
response to peptide hormone GO:0043434 278 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
intracellular signal transduction GO:0035556 314 0.038
Mouse
regulation of apoptotic process GO:0042981 335 0.038
purine containing compound metabolic process GO:0072521 253 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
hormone transport GO:0009914 121 0.037
regulation of protein phosphorylation GO:0001932 183 0.037
response to biotic stimulus GO:0009607 226 0.036
purine nucleoside catabolic process GO:0006152 124 0.036
rna metabolic process GO:0016070 406 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
carbohydrate derivative catabolic process GO:1901136 147 0.036
regulation of b cell proliferation GO:0030888 6 0.036
motor neuron axon guidance GO:0008045 1 0.036
intracellular transport GO:0046907 185 0.036
positive regulation of smooth muscle cell migration GO:0014911 27 0.036
Human
t cell tolerance induction GO:0002517 3 0.035
interleukin 1 beta secretion GO:0050702 3 0.035
divalent inorganic cation homeostasis GO:0072507 165 0.035
regulation of cell differentiation GO:0045595 320 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
sensory perception GO:0007600 101 0.035
regulation of tolerance induction to nonself antigen GO:0002655 1 0.035
negative regulation of lymphocyte proliferation GO:0050672 6 0.035
monocarboxylic acid biosynthetic process GO:0072330 48 0.035
negative regulation of cell proliferation GO:0008285 119 0.035
Human
regulation of neutrophil apoptotic process GO:0033029 4 0.034
organic cyclic compound catabolic process GO:1901361 175 0.034
detection of stimulus GO:0051606 24 0.034
positive regulation of cell differentiation GO:0045597 217 0.034
negative regulation of leukocyte apoptotic process GO:2000107 4 0.034
cellular divalent inorganic cation homeostasis GO:0072503 162 0.034
regulation of leukocyte mediated immunity GO:0002703 19 0.034
positive regulation of secretion by cell GO:1903532 128 0.033
regulation of cell development GO:0060284 263 0.033
negative regulation of cell killing GO:0031342 5 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
regulation of neuron death GO:1901214 115 0.033
ribonucleoside triphosphate metabolic process GO:0009199 141 0.032
multi organism reproductive process GO:0044703 262 0.032
hematopoietic progenitor cell differentiation GO:0002244 2 0.032
regulation of neuron apoptotic process GO:0043523 83 0.032
glycosyl compound metabolic process GO:1901657 182 0.031
negative regulation of immune response GO:0050777 15 0.031
cellular response to organic cyclic compound GO:0071407 202 0.031
divalent inorganic cation transport GO:0072511 134 0.031
positive regulation of cell development GO:0010720 176 0.031
single organism reproductive process GO:0044702 297 0.031
antigen receptor mediated signaling pathway GO:0050851 1 0.030
response to other organism GO:0051707 220 0.030
regulation of phosphorylation GO:0042325 248 0.030
regulation of lymphocyte mediated immunity GO:0002706 11 0.030
muscle cell migration GO:0014812 36 0.030
Human
cellular cation homeostasis GO:0030003 180 0.030
antigen processing and presentation of exogenous antigen GO:0019884 1 0.030
regulation of interleukin 1 secretion GO:0050704 3 0.030
purine nucleoside metabolic process GO:0042278 169 0.030
single organism biosynthetic process GO:0044711 342 0.030
regulation of neurogenesis GO:0050767 247 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
single organism catabolic process GO:0044712 283 0.029
positive regulation of developmental process GO:0051094 283 0.029
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
inflammatory response GO:0006954 150 0.029
positive regulation of apoptotic process GO:0043065 154 0.029
cellular response to cytokine stimulus GO:0071345 127 0.029
regulation of molecular function GO:0065009 398 0.028
cytosolic calcium ion homeostasis GO:0051480 140 0.028
positive regulation of chemokine production GO:0032722 4 0.028
regulation of body fluid levels GO:0050878 90 0.028
nucleoside triphosphate catabolic process GO:0009143 123 0.028
organic substance catabolic process GO:1901575 316 0.028
localization of cell GO:0051674 202 0.028
negative regulation of protein metabolic process GO:0051248 114 0.028
negative regulation of leukocyte mediated immunity GO:0002704 6 0.027
regulation of hormone levels GO:0010817 187 0.027
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.027
negative regulation of molecular function GO:0044092 133 0.027
leukocyte mediated immunity GO:0002443 28 0.027
sensory perception of pain GO:0019233 73 0.027
cellular response to tumor necrosis factor GO:0071356 46 0.027
guanosine containing compound metabolic process GO:1901068 74 0.027
cellular response to insulin stimulus GO:0032869 81 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
response to cold GO:0009409 29 0.027
negative regulation of phosphate metabolic process GO:0045936 80 0.027
regulation of cellular component movement GO:0051270 150 0.027
positive regulation of cell death GO:0010942 184 0.027
response to ethanol GO:0045471 162 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
membrane organization GO:0061024 94 0.026
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.026
antigen processing and presentation of exogenous peptide antigen GO:0002478 1 0.026
cell projection organization GO:0030030 302 0.026
Mouse
regulation of protein modification process GO:0031399 194 0.026
cellular catabolic process GO:0044248 295 0.026
axonogenesis GO:0007409 71 0.026
antigen processing and presentation GO:0019882 2 0.026
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.026
positive regulation of protein kinase activity GO:0045860 73 0.026
lymphocyte mediated immunity GO:0002449 14 0.026
cell cell signaling GO:0007267 335 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.025
response to tumor necrosis factor GO:0034612 56 0.025
regulation of t cell proliferation GO:0042129 17 0.025
Human
purine ribonucleoside metabolic process GO:0046128 168 0.025
regulation of interleukin 1 production GO:0032652 11 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
Human Mouse
response to hypoxia GO:0001666 231 0.025
organophosphate metabolic process GO:0019637 370 0.024
negative regulation of mononuclear cell proliferation GO:0032945 6 0.024
myeloid leukocyte activation GO:0002274 36 0.024
cyclic nucleotide metabolic process GO:0009187 80 0.024
purine containing compound catabolic process GO:0072523 138 0.024
mononuclear cell proliferation GO:0032943 29 0.024
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.024
organelle organization GO:0006996 266 0.024
Human Mouse
negative regulation of biosynthetic process GO:0009890 168 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 8 0.024
response to growth factor GO:0070848 189 0.024
response to monosaccharide GO:0034284 159 0.024
heterocycle catabolic process GO:0046700 167 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
regeneration GO:0031099 163 0.024
eye morphogenesis GO:0048592 4 0.024
positive regulation of cytokine production GO:0001819 42 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
defense response to virus GO:0051607 9 0.023
cellular response to ammonium ion GO:0071242 17 0.023
response to wounding GO:0009611 254 0.023
cellular component biogenesis GO:0044085 368 0.023
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
negative regulation of protein modification process GO:0031400 52 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
regulation of cellular localization GO:0060341 263 0.023
cell type specific apoptotic process GO:0097285 134 0.023
ribonucleoside triphosphate catabolic process GO:0009203 122 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
lymphocyte proliferation GO:0046651 29 0.022
Human
regulation of nervous system development GO:0051960 264 0.022
response to camp GO:0051591 91 0.022
regulation of protein metabolic process GO:0051246 289 0.022
smooth muscle cell migration GO:0014909 36 0.022
Human
cation transport GO:0006812 382 0.022
response to hydrogen peroxide GO:0042542 89 0.022
positive regulation of lymphocyte activation GO:0051251 25 0.022
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
circulatory system process GO:0003013 183 0.022
t cell receptor signaling pathway GO:0050852 1 0.021
response to purine containing compound GO:0014074 126 0.021
positive regulation of response to external stimulus GO:0032103 51 0.021
Human
positive regulation of retinal cell programmed cell death GO:0046670 1 0.021
digestive system development GO:0055123 41 0.021
regulation of cell projection organization GO:0031344 175 0.021
detection of abiotic stimulus GO:0009582 13 0.021
sleep GO:0030431 30 0.021
wound healing GO:0042060 122 0.021
osteoblast differentiation GO:0001649 26 0.021
response to estrogen GO:0043627 232 0.021
response to gamma radiation GO:0010332 24 0.021
midgut development GO:0007494 13 0.020
organ regeneration GO:0031100 101 0.020
positive regulation of immune system process GO:0002684 90 0.020
Human
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
regulation of anatomical structure size GO:0090066 135 0.020
hematopoietic or lymphoid organ development GO:0048534 36 0.020
positive regulation of signal transduction GO:0009967 175 0.020
tube development GO:0035295 89 0.020
response to oxygen levels GO:0070482 265 0.020
interleukin 1 secretion GO:0050701 3 0.020
sequestering of metal ion GO:0051238 9 0.020
cell morphogenesis GO:0000902 142 0.020
leukocyte proliferation GO:0070661 29 0.019
Human
establishment of protein localization GO:0045184 141 0.019
negative regulation of phosphorylation GO:0042326 57 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
gastrulation GO:0007369 2 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.019
positive regulation of cell killing GO:0031343 9 0.019
cellular response to alkaloid GO:0071312 25 0.019
divalent metal ion transport GO:0070838 132 0.019
neutrophil homeostasis GO:0001780 4 0.019
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.019
positive regulation of leukocyte activation GO:0002696 30 0.019
Human
small molecule biosynthetic process GO:0044283 124 0.019
negative regulation of defense response GO:0031348 19 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
icosanoid metabolic process GO:0006690 38 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.019
secretion GO:0046903 307 0.019
positive regulation of protein modification process GO:0031401 142 0.018
tissue remodeling GO:0048771 40 0.018
cellular response to reactive oxygen species GO:0034614 55 0.018
regulation of interleukin 1 beta production GO:0032651 7 0.018
olfactory learning GO:0008355 1 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
hemopoiesis GO:0030097 34 0.018
negative regulation of lymphocyte activation GO:0051250 10 0.018
response to vitamin GO:0033273 131 0.018
apoptotic process GO:0006915 381 0.018
amide transport GO:0042886 105 0.018
regulation of secretion by cell GO:1903530 208 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
learning or memory GO:0007611 90 0.018
memory GO:0007613 54 0.018
positive regulation of interleukin 1 beta secretion GO:0050718 3 0.018
positive regulation of t cell mediated immunity GO:0002711 4 0.018
negative regulation of developmental process GO:0051093 125 0.018
transcription dna templated GO:0006351 377 0.018
mapk cascade GO:0000165 140 0.018
regulation of transcription dna templated GO:0006355 374 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
positive regulation of leukocyte mediated immunity GO:0002705 13 0.018
nucleotide biosynthetic process GO:0009165 98 0.017
cellular response to stress GO:0033554 269 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
Mouse
response to calcium ion GO:0051592 59 0.017
regulation of cell cycle GO:0051726 73 0.017
Human
fatty acid biosynthetic process GO:0006633 33 0.017
defense response to gram positive bacterium GO:0050830 2 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
positive regulation of signaling GO:0023056 270 0.017
atp catabolic process GO:0006200 54 0.017
cellular response to camp GO:0071320 26 0.017
platelet aggregation GO:0070527 4 0.017
response to x ray GO:0010165 15 0.017
response to glucose GO:0009749 136 0.017
regulation of neuron differentiation GO:0045664 208 0.017
regulation of signal transduction GO:0009966 318 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
axis specification GO:0009798 4 0.017
regulation of catalytic activity GO:0050790 304 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
protein oligomerization GO:0051259 191 0.016
regulation of membrane potential GO:0042391 110 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
adaptive immune response GO:0002250 14 0.016
positive regulation of interleukin 1 secretion GO:0050716 3 0.016
regulation of cell motility GO:2000145 131 0.016
metal ion transport GO:0030001 289 0.016
reproductive process GO:0022414 372 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.016
positive regulation of cell communication GO:0010647 271 0.016
cellular component assembly GO:0022607 360 0.016
Human Mouse
negative regulation of catalytic activity GO:0043086 103 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
response to alkaloid GO:0043279 132 0.016
leukotriene biosynthetic process GO:0019370 3 0.016
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.016
response to cytokine GO:0034097 215 0.016
sexual reproduction GO:0019953 148 0.015
cellular response to iron ion starvation GO:0010106 1 0.015
regulation of leukocyte apoptotic process GO:2000106 5 0.015
regulation of protein kinase activity GO:0045859 105 0.015
negative regulation of adaptive immune response GO:0002820 1 0.015
response to oxidative stress GO:0006979 186 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
nucleotide catabolic process GO:0009166 139 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
lipid metabolic process GO:0006629 283 0.015
gamete generation GO:0007276 124 0.015
gtp catabolic process GO:0006184 71 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.015
olfactory behavior GO:0042048 2 0.015
intracellular protein transport GO:0006886 79 0.015
hormone secretion GO:0046879 115 0.015
regulation of tolerance induction GO:0002643 2 0.015
reproductive structure development GO:0048608 128 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
blood coagulation GO:0007596 26 0.015
positive regulation of gene expression GO:0010628 244 0.015
regulation of locomotion GO:0040012 148 0.015
positive regulation of transport GO:0051050 245 0.015
regulation of circadian sleep wake cycle GO:0042749 18 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
endomembrane system organization GO:0010256 48 0.015
protein localization GO:0008104 191 0.015
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.014
rho protein signal transduction GO:0007266 11 0.014
negative regulation of signaling GO:0023057 157 0.014
rna biosynthetic process GO:0032774 380 0.014
positive regulation of neuron death GO:1901216 43 0.014
biological adhesion GO:0022610 110 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
toxin transport GO:1901998 3 0.014
peptidyl amino acid modification GO:0018193 126 0.014
response to interferon gamma GO:0034341 20 0.014
circadian rhythm GO:0007623 88 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
negative regulation of cell communication GO:0010648 158 0.014
positive regulation of cell activation GO:0050867 34 0.014
Human
icosanoid biosynthetic process GO:0046456 18 0.014
response to amino acid GO:0043200 75 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
negative regulation of lymphocyte mediated immunity GO:0002707 5 0.014
response to axon injury GO:0048678 59 0.014
axon development GO:0061564 96 0.014
forebrain development GO:0030900 98 0.014
negative regulation of response to wounding GO:1903035 23 0.014
positive regulation of humoral immune response GO:0002922 2 0.014
reproductive system development GO:0061458 128 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
regulation of blood circulation GO:1903522 110 0.014
renal system development GO:0072001 67 0.014
fatty acid derivative metabolic process GO:1901568 38 0.014
leukocyte apoptotic process GO:0071887 6 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
leukocyte migration GO:0050900 38 0.013
Human
negative regulation of gene expression GO:0010629 199 0.013

Aif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.091
disease of anatomical entity DOID:7 0 0.091
vascular disease DOID:178 0 0.020
cardiovascular system disease DOID:1287 0 0.020
connective tissue disease DOID:65 0 0.015
immune system disease DOID:2914 0 0.014