Rattus norvegicus

0 known processes

Akap4

A kinase (PRKA) anchor protein 4

Akap4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.253
neuron projection development GO:0031175 273 0.192
g protein coupled receptor signaling pathway GO:0007186 242 0.169
regulation of cellular component organization GO:0051128 368 0.130
cellular response to endogenous stimulus GO:0071495 377 0.112
kidney development GO:0001822 67 0.102
cellular hormone metabolic process GO:0034754 49 0.091
cellular amino acid metabolic process GO:0006520 107 0.091
positive regulation of multicellular organismal process GO:0051240 387 0.085
blood circulation GO:0008015 183 0.085
regulation of cellular amino acid metabolic process GO:0006521 2 0.080
defense response GO:0006952 194 0.073
cellular response to cytokine stimulus GO:0071345 127 0.071
carboxylic acid metabolic process GO:0019752 289 0.067
regulation of neurogenesis GO:0050767 247 0.066
programmed cell death GO:0012501 392 0.066
n methyl d aspartate receptor clustering GO:0097114 2 0.062
cellular response to hormone stimulus GO:0032870 247 0.062
estrogen biosynthetic process GO:0006703 6 0.060
negative regulation of chronic inflammatory response GO:0002677 2 0.060
neuron differentiation GO:0030182 368 0.058
amine metabolic process GO:0009308 38 0.056
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.054
regulation of secretion by cell GO:1903530 208 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
tolerance induction to nonself antigen GO:0002462 2 0.051
response to nutrient levels GO:0031667 370 0.051
cell projection organization GO:0030030 302 0.049
positive regulation of transport GO:0051050 245 0.049
oxoacid metabolic process GO:0043436 290 0.049
cellular component morphogenesis GO:0032989 155 0.049
regulation of neuron differentiation GO:0045664 208 0.049
response to vitamin GO:0033273 131 0.048
neuron development GO:0048666 286 0.048
negative regulation of serine type endopeptidase activity GO:1900004 1 0.048
regulation of signal transduction GO:0009966 318 0.047
cellular ketone metabolic process GO:0042180 51 0.046
protein complex subunit organization GO:0071822 302 0.045
tissue development GO:0009888 252 0.044
locomotion GO:0040011 237 0.042
Human
negative regulation of cell death GO:0060548 229 0.042
intracellular signal transduction GO:0035556 314 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.040
response to growth factor GO:0070848 189 0.039
response to organophosphorus GO:0046683 102 0.039
circulatory system process GO:0003013 183 0.039
positive regulation of protein modification process GO:0031401 142 0.039
response to extracellular stimulus GO:0009991 380 0.039
complement receptor mediated signaling pathway GO:0002430 2 0.038
regulation of cell development GO:0060284 263 0.038
brain renin angiotensin system GO:0002035 3 0.038
multicellular organism reproduction GO:0032504 233 0.038
cellular amine metabolic process GO:0044106 38 0.037
regulation of neuron projection development GO:0010975 161 0.037
circulatory system development GO:0072359 134 0.037
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.036
regulation of vesicle mediated transport GO:0060627 81 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.034
regulation of nervous system development GO:0051960 264 0.034
regulation of catalytic activity GO:0050790 304 0.034
positive regulation of catalytic activity GO:0043085 184 0.033
regulation of tube size GO:0035150 89 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
tissue remodeling GO:0048771 40 0.032
cell activation GO:0001775 97 0.032
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.032
secretion GO:0046903 307 0.032
regulation of blood vessel size GO:0050880 89 0.031
telencephalon development GO:0021537 62 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
macromolecule localization GO:0033036 252 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.030
cellular metal ion homeostasis GO:0006875 172 0.030
tonic smooth muscle contraction GO:0014820 4 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.029
epithelium development GO:0060429 96 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
organic acid metabolic process GO:0006082 292 0.028
secretion by cell GO:0032940 248 0.028
positive regulation of blood circulation GO:1903524 65 0.028
muscle contraction GO:0006936 88 0.028
purine ribonucleoside metabolic process GO:0046128 168 0.027
cell morphogenesis GO:0000902 142 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
cellular component biogenesis GO:0044085 368 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
negative regulation of signaling GO:0023057 157 0.027
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.027
positive regulation of molecular function GO:0044093 230 0.027
muscle system process GO:0003012 115 0.027
regulation of cell projection organization GO:0031344 175 0.026
protein complex biogenesis GO:0070271 263 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
transcription dna templated GO:0006351 377 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
chemical homeostasis GO:0048878 292 0.026
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
regulation of apoptotic process GO:0042981 335 0.025
inflammatory response GO:0006954 150 0.025
cellular component assembly GO:0022607 360 0.025
biological adhesion GO:0022610 110 0.025
oligopeptide transport GO:0006857 4 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
cerebral cortex tangential migration GO:0021800 1 0.025
cellular cation homeostasis GO:0030003 180 0.025
central nervous system development GO:0007417 311 0.025
regulation of molecular function GO:0065009 398 0.024
response to cytokine GO:0034097 215 0.024
regulation of secretion GO:0051046 224 0.024
nucleoside metabolic process GO:0009116 179 0.024
leydig cell differentiation GO:0033327 8 0.024
regulation of programmed cell death GO:0043067 341 0.024
hormone metabolic process GO:0042445 69 0.024
regulation of cell proliferation GO:0042127 359 0.024
cellular response to lipopolysaccharide GO:0071222 55 0.024
peptidyl tyrosine phosphorylation GO:0018108 72 0.023
tolerance induction dependent upon immune response GO:0002461 2 0.023
urogenital system development GO:0001655 78 0.023
regulation of protein metabolic process GO:0051246 289 0.023
neurological system process GO:0050877 219 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
regulation of cell differentiation GO:0045595 320 0.023
cell motility GO:0048870 202 0.023
Human
apoptotic process GO:0006915 381 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
immune system process GO:0002376 204 0.023
proteolysis GO:0006508 175 0.022
ion homeostasis GO:0050801 212 0.022
protein complex assembly GO:0006461 263 0.022
protein phosphorylation GO:0006468 345 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
regulation of behavior GO:0050795 61 0.022
motor neuron axon guidance GO:0008045 1 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
regulation of blood circulation GO:1903522 110 0.021
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 13 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
blood vessel morphogenesis GO:0048514 58 0.021
ras protein signal transduction GO:0007265 29 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
regulation of immune system process GO:0002682 123 0.020
brain development GO:0007420 247 0.020
blood vessel development GO:0001568 69 0.020
phototransduction visible light GO:0007603 2 0.020
ribonucleotide biosynthetic process GO:0009260 85 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
nitrogen compound transport GO:0071705 229 0.019
regulation of kinase activity GO:0043549 117 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.019
sensory perception of pain GO:0019233 73 0.019
cardiac muscle contraction GO:0060048 27 0.019
multi multicellular organism process GO:0044706 138 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
macromolecular complex assembly GO:0065003 273 0.018
cellular ion homeostasis GO:0006873 184 0.018
forebrain development GO:0030900 98 0.018
heart process GO:0003015 57 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
artery smooth muscle contraction GO:0014824 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of system process GO:0044057 208 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
neurotransmitter gated ion channel clustering GO:0072578 3 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.016
regulation of serine type endopeptidase activity GO:1900003 1 0.016
glomerular mesangium development GO:0072109 4 0.016
positive regulation of nervous system development GO:0051962 178 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.016
response to mechanical stimulus GO:0009612 134 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
reproduction GO:0000003 245 0.016
inner ear morphogenesis GO:0042472 1 0.016
positive regulation of cell communication GO:0010647 271 0.016
phospholipid metabolic process GO:0006644 61 0.016
regulation of locomotion GO:0040012 148 0.016
cellular homeostasis GO:0019725 252 0.016
negative regulation of transport GO:0051051 136 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
intestinal absorption GO:0050892 3 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
glomerular mesangial cell proliferation GO:0072110 4 0.015
regulation of blood pressure GO:0008217 83 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to estradiol GO:0032355 164 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
protein secretion GO:0009306 34 0.015
establishment of synaptic vesicle localization GO:0097480 23 0.015
response to cadmium ion GO:0046686 35 0.015
cell adhesion GO:0007155 110 0.015
calcium ion homeostasis GO:0055074 162 0.015
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
positive regulation of signal transduction GO:0009967 175 0.014
fertilization GO:0009566 3 0.014
metal ion homeostasis GO:0055065 186 0.014
vasodilation GO:0042311 44 0.014
negative regulation of gene expression GO:0010629 199 0.014
cellular component movement GO:0006928 248 0.014
Human
transmission of nerve impulse GO:0019226 42 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.014
retina morphogenesis in camera type eye GO:0060042 1 0.014
rho protein signal transduction GO:0007266 11 0.014
negative regulation of axon guidance GO:1902668 3 0.014
regulation of cell growth GO:0001558 85 0.014
regulation of protein modification process GO:0031399 194 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
organic hydroxy compound transport GO:0015850 77 0.014
response to oxygen levels GO:0070482 265 0.014
nucleic acid templated transcription GO:0097659 379 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
signal release GO:0023061 145 0.014
striated muscle tissue development GO:0014706 58 0.014
renal system process GO:0003014 40 0.014
response to purine containing compound GO:0014074 126 0.014
positive regulation of renin secretion into blood stream GO:1900135 1 0.013
peptide biosynthetic process GO:0043043 3 0.013
organophosphate metabolic process GO:0019637 370 0.013
steroid metabolic process GO:0008202 73 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
metanephric tubule development GO:0072170 4 0.013
multi organism reproductive process GO:0044703 262 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to wounding GO:0009611 254 0.013
positive regulation of cell proliferation involved in kidney development GO:1901724 4 0.013
homeostatic process GO:0042592 331 0.013
negative regulation of cell communication GO:0010648 158 0.012
saliva secretion GO:0046541 3 0.012
intracellular transport GO:0046907 185 0.012
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.012
rna metabolic process GO:0016070 406 0.012
neurotransmitter transport GO:0006836 42 0.012
striated muscle contraction GO:0006941 44 0.012
reproductive process GO:0022414 372 0.012
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.012
pallium development GO:0021543 42 0.012
ossification GO:0001503 70 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
positive regulation of transferase activity GO:0051347 81 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.012
localization of cell GO:0051674 202 0.012
Human
response to estrogen GO:0043627 232 0.012
positive regulation of secretion GO:0051047 140 0.012
positive regulation of signaling GO:0023056 270 0.012
leukocyte activation GO:0045321 76 0.012
cell growth GO:0016049 104 0.012
response to antibiotic GO:0046677 39 0.011
urinary bladder smooth muscle contraction GO:0014832 4 0.011
axon development GO:0061564 96 0.011
angiogenesis GO:0001525 53 0.011
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of cellular localization GO:0060341 263 0.011
detection of visible light GO:0009584 3 0.011
response to ddt GO:0046680 1 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of glomerulus development GO:0090193 4 0.011
regulation of saliva secretion GO:0046877 3 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
response to inorganic substance GO:0010035 377 0.011
regulation of phosphorylation GO:0042325 248 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
organelle organization GO:0006996 266 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
monoamine transport GO:0015844 43 0.011
peptide transport GO:0015833 97 0.011
positive regulation of immune system process GO:0002684 90 0.011
carboxylic acid transport GO:0046942 115 0.011
calcium ion transport GO:0006816 131 0.011
diaphragm contraction GO:0002086 2 0.011
cell migration GO:0016477 197 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
purine containing compound metabolic process GO:0072521 253 0.011
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.011
gliogenesis GO:0042063 93 0.011
regulation of synaptic transmission GO:0050804 141 0.011
metanephric epithelium development GO:0072207 4 0.011
regulation of hydrolase activity GO:0051336 143 0.011
vasculature development GO:0001944 70 0.011
regulation of renal sodium excretion GO:0035813 20 0.011
tumor necrosis factor biosynthetic process GO:0042533 1 0.010
organ morphogenesis GO:0009887 75 0.010
multicellular organism growth GO:0035264 1 0.010
response to toxic substance GO:0009636 133 0.010
protein oligomerization GO:0051259 191 0.010
protein localization GO:0008104 191 0.010
substrate dependent cell migration GO:0006929 1 0.010
phosphatidylinositol dephosphorylation GO:0046856 4 0.010
response to metal ion GO:0010038 253 0.010
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.010
head development GO:0060322 247 0.010
glomerulus development GO:0032835 10 0.010
response to acid chemical GO:0001101 222 0.010

Akap4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
sensory system disease DOID:0050155 0 0.051
eye and adnexa disease DOID:1492 0 0.051
nervous system disease DOID:863 0 0.051
eye disease DOID:5614 0 0.051
retinal disease DOID:5679 0 0.051
retinitis pigmentosa DOID:10584 0 0.026
retinal degeneration DOID:8466 0 0.026
cardiovascular system disease DOID:1287 0 0.014