Rattus norvegicus

0 known processes

Akr1b7

aldo-keto reductase family 1, member B7

(Aliases: MVDP,Avdp)

Akr1b7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative metabolic process GO:1901135 346 0.128
Human
purine ribonucleotide metabolic process GO:0009150 227 0.126
regulation of phosphorus metabolic process GO:0051174 349 0.100
regulation of hydrolase activity GO:0051336 143 0.097
regulation of catalytic activity GO:0050790 304 0.085
nucleobase containing small molecule metabolic process GO:0055086 316 0.082
organic acid metabolic process GO:0006082 292 0.080
negative regulation of cellular metabolic process GO:0031324 281 0.073
cellular response to stress GO:0033554 269 0.073
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.067
negative regulation of metabolic process GO:0009892 331 0.066
cellular response to hormone stimulus GO:0032870 247 0.060
response to cytokine GO:0034097 215 0.060
regulation of hormone levels GO:0010817 187 0.058
Rat
ribonucleotide metabolic process GO:0009259 231 0.057
regulation of cellular protein metabolic process GO:0032268 267 0.056
regulation of protein metabolic process GO:0051246 289 0.053
response to oxidative stress GO:0006979 186 0.050
Rat
response to biotic stimulus GO:0009607 226 0.050
response to carbohydrate GO:0009743 183 0.049
apoptotic process GO:0006915 381 0.048
response to external biotic stimulus GO:0043207 221 0.048
response to peptide GO:1901652 292 0.048
Rat
reproductive process GO:0022414 372 0.047
Rat
rna metabolic process GO:0016070 406 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
carboxylic acid metabolic process GO:0019752 289 0.045
multicellular organism reproduction GO:0032504 233 0.045
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.044
regulation of molecular function GO:0065009 398 0.043
purine containing compound metabolic process GO:0072521 253 0.043
response to extracellular stimulus GO:0009991 380 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
regulation of cellular component organization GO:0051128 368 0.041
cellular response to organonitrogen compound GO:0071417 197 0.040
Rat
response to other organism GO:0051707 220 0.040
multicellular organismal reproductive process GO:0048609 233 0.039
Rat
regulation of rna biosynthetic process GO:2001141 381 0.039
regulation of purine nucleotide metabolic process GO:1900542 115 0.039
purine nucleotide metabolic process GO:0006163 229 0.038
negative regulation of cell death GO:0060548 229 0.038
nucleotide metabolic process GO:0009117 279 0.038
response to hexose GO:0009746 144 0.037
regulation of transcription dna templated GO:0006355 374 0.037
divalent metal ion transport GO:0070838 132 0.037
regulation of programmed cell death GO:0043067 341 0.037
regulation of blood pressure GO:0008217 83 0.036
hormone transport GO:0009914 121 0.036
regulation of mapk cascade GO:0043408 116 0.036
negative regulation of programmed cell death GO:0043069 183 0.035
response to inorganic substance GO:0010035 377 0.035
Rat
response to nutrient levels GO:0031667 370 0.034
single organism biosynthetic process GO:0044711 342 0.034
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.033
organophosphate metabolic process GO:0019637 370 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
cellular response to nitrogen compound GO:1901699 210 0.032
Rat
cellular amine metabolic process GO:0044106 38 0.032
smooth muscle cell proliferation GO:0048659 77 0.032
Rat
regulation of apoptotic process GO:0042981 335 0.031
single organism catabolic process GO:0044712 283 0.031
Human
positive regulation of catalytic activity GO:0043085 184 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
response to bacterium GO:0009617 200 0.031
regulation of smooth muscle cell proliferation GO:0048660 75 0.031
Rat
glycosyl compound metabolic process GO:1901657 182 0.031
Human
positive regulation of rna metabolic process GO:0051254 203 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
programmed cell death GO:0012501 392 0.031
regulation of protein modification process GO:0031399 194 0.030
organic substance catabolic process GO:1901575 316 0.029
Human
aromatic compound catabolic process GO:0019439 168 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
purine nucleotide biosynthetic process GO:0006164 83 0.029
response to monosaccharide GO:0034284 159 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
regulation of rna metabolic process GO:0051252 391 0.028
divalent inorganic cation transport GO:0072511 134 0.028
cellular ketone metabolic process GO:0042180 51 0.027
Human
regulation of nucleotide metabolic process GO:0006140 117 0.027
regulation of catabolic process GO:0009894 113 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
Rat
regulation of jnk cascade GO:0046328 19 0.026
regulation of hormone secretion GO:0046883 106 0.026
single organism reproductive process GO:0044702 297 0.026
Rat
cellular response to external stimulus GO:0071496 118 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.026
response to peptide hormone GO:0043434 278 0.026
regulation of response to stress GO:0080134 126 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
female sex differentiation GO:0046660 59 0.026
regulation of protein maturation GO:1903317 50 0.026
regulation of phosphorylation GO:0042325 248 0.026
cellular response to peptide GO:1901653 133 0.025
Rat
proteolysis GO:0006508 175 0.025
response to estrogen GO:0043627 232 0.025
Rat
cellular component morphogenesis GO:0032989 155 0.025
protein phosphorylation GO:0006468 345 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
positive regulation of protein phosphorylation GO:0001934 135 0.025
regulation of cell development GO:0060284 263 0.025
regulation of cell proliferation GO:0042127 359 0.025
Rat
response to starvation GO:0042594 59 0.025
calcium ion transport GO:0006816 131 0.025
intracellular signal transduction GO:0035556 314 0.024
Rat
secretion GO:0046903 307 0.024
stress activated mapk cascade GO:0051403 35 0.024
negative regulation of catalytic activity GO:0043086 103 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
Rat
organophosphate biosynthetic process GO:0090407 143 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
protein maturation GO:0051604 68 0.023
metal ion transport GO:0030001 289 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
purine ribonucleoside catabolic process GO:0046130 124 0.023
negative regulation of molecular function GO:0044092 133 0.022
protein processing GO:0016485 68 0.022
purine containing compound biosynthetic process GO:0072522 85 0.022
aging GO:0007568 241 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
secretion by cell GO:0032940 248 0.022
glycosyl compound catabolic process GO:1901658 126 0.022
regulation of cell growth GO:0001558 85 0.021
defense response GO:0006952 194 0.021
nucleic acid templated transcription GO:0097659 379 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
Rat
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
stress activated protein kinase signaling cascade GO:0031098 37 0.021
Rat
purine nucleoside catabolic process GO:0006152 124 0.021
response to glucose GO:0009749 136 0.021
organic anion transport GO:0015711 132 0.021
cation transport GO:0006812 382 0.021
reproduction GO:0000003 245 0.020
Rat
rna biosynthetic process GO:0032774 380 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
organelle organization GO:0006996 266 0.020
gonad development GO:0008406 104 0.020
signal release GO:0023061 145 0.020
response to nutrient GO:0007584 248 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
response to metal ion GO:0010038 253 0.020
purine containing compound catabolic process GO:0072523 138 0.020
nitrogen compound transport GO:0071705 229 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.019
carbohydrate metabolic process GO:0005975 130 0.019
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.019
transmembrane transport GO:0055085 412 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
transcription dna templated GO:0006351 377 0.019
negative regulation of gene expression GO:0010629 199 0.019
amine metabolic process GO:0009308 38 0.019
ribonucleotide biosynthetic process GO:0009260 85 0.019
positive regulation of molecular function GO:0044093 230 0.019
rhythmic process GO:0048511 156 0.019
regulation of nucleoside metabolic process GO:0009118 66 0.019
purine nucleotide catabolic process GO:0006195 136 0.018
cell morphogenesis GO:0000902 142 0.018
response to hydrogen peroxide GO:0042542 89 0.018
Rat
negative regulation of apoptotic process GO:0043066 181 0.018
regulation of cell differentiation GO:0045595 320 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
response to decreased oxygen levels GO:0036293 237 0.018
actin filament based process GO:0030029 86 0.018
positive regulation of developmental process GO:0051094 283 0.018
hormone secretion GO:0046879 115 0.018
regulation of nucleotide biosynthetic process GO:0030808 47 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
regulation of cellular localization GO:0060341 263 0.018
cellular response to cytokine stimulus GO:0071345 127 0.018
nucleotide catabolic process GO:0009166 139 0.018
oxoacid metabolic process GO:0043436 290 0.018
positive regulation of cell death GO:0010942 184 0.018
regulation of nervous system development GO:0051960 264 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
ion homeostasis GO:0050801 212 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
regulation of cell projection organization GO:0031344 175 0.017
cellular homeostasis GO:0019725 252 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
positive regulation of nervous system development GO:0051962 178 0.017
negative regulation of neuron death GO:1901215 69 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
response to reactive oxygen species GO:0000302 120 0.017
Rat
ribonucleoside metabolic process GO:0009119 174 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
lipid metabolic process GO:0006629 283 0.017
Human Rat
response to hypoxia GO:0001666 231 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
cation homeostasis GO:0055080 195 0.017
regulation of stress activated mapk cascade GO:0032872 23 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
lipid transport GO:0006869 61 0.016
regulation of neuron death GO:1901214 115 0.016
protein complex subunit organization GO:0071822 302 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
reproductive system development GO:0061458 128 0.016
cell growth GO:0016049 104 0.016
heterocycle catabolic process GO:0046700 167 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
organic acid biosynthetic process GO:0016053 83 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
nucleoside catabolic process GO:0009164 126 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
jnk cascade GO:0007254 28 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
sex differentiation GO:0007548 113 0.016
male sex differentiation GO:0046661 64 0.016
reactive oxygen species metabolic process GO:0072593 37 0.016
cyclic purine nucleotide metabolic process GO:0052652 62 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
gamete generation GO:0007276 124 0.015
mapk cascade GO:0000165 140 0.015
sterol homeostasis GO:0055092 3 0.015
glucose homeostasis GO:0042593 75 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
negative regulation of response to external stimulus GO:0032102 37 0.015
multi multicellular organism process GO:0044706 138 0.015
Rat
sequestering of calcium ion GO:0051208 8 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of gene expression GO:0010628 244 0.015
growth GO:0040007 165 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.015
regulation of transferase activity GO:0051338 123 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
neuron development GO:0048666 286 0.015
regulation of endopeptidase activity GO:0052548 51 0.015
peptide transport GO:0015833 97 0.015
neuron projection development GO:0031175 273 0.015
cell type specific apoptotic process GO:0097285 134 0.015
positive regulation of locomotion GO:0040017 102 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
cell adhesion GO:0007155 110 0.014
biological adhesion GO:0022610 110 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of system process GO:0044057 208 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
cellular response to glucocorticoid stimulus GO:0071385 68 0.014
neuron death GO:0070997 127 0.014
negative regulation of cell communication GO:0010648 158 0.014
endocrine process GO:0050886 32 0.014
muscle cell proliferation GO:0033002 84 0.014
Rat
cellular response to extracellular stimulus GO:0031668 73 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
regulation of metal ion transport GO:0010959 118 0.014
response to lipopolysaccharide GO:0032496 191 0.014
regulation of cellular response to stress GO:0080135 49 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
multi organism reproductive process GO:0044703 262 0.014
Rat
positive regulation of calcium ion transport GO:0051928 36 0.014
female pregnancy GO:0007565 122 0.014
Rat
sequestering of metal ion GO:0051238 9 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
regulation of multicellular organismal development GO:2000026 376 0.013
response to ethanol GO:0045471 162 0.013
regulation of protein processing GO:0070613 50 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
response to vitamin GO:0033273 131 0.013
response to corticosteroid GO:0031960 235 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to estradiol GO:0032355 164 0.013
organophosphate catabolic process GO:0046434 148 0.013
metal ion homeostasis GO:0055065 186 0.013
response to glucocorticoid GO:0051384 223 0.013
response to cold GO:0009409 29 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
peptidyl amino acid modification GO:0018193 126 0.013
regulation of kinase activity GO:0043549 117 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
negative regulation of response to biotic stimulus GO:0002832 4 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
catabolic process GO:0009056 351 0.012
Human
cellular response to organic cyclic compound GO:0071407 202 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
sexual reproduction GO:0019953 148 0.012
cellular cation homeostasis GO:0030003 180 0.012
spermatogenesis GO:0007283 99 0.012
regulation of peptidase activity GO:0052547 55 0.012
lipid storage GO:0019915 1 0.012
central nervous system development GO:0007417 311 0.012
Rat Fly
protein oligomerization GO:0051259 191 0.012
regulation of proteolysis GO:0030162 66 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
positive regulation of cell development GO:0010720 176 0.012
negative regulation of protein maturation GO:1903318 47 0.012
amide transport GO:0042886 105 0.012
positive regulation of cell migration GO:0030335 96 0.012
cellular component biogenesis GO:0044085 368 0.012
macromolecule localization GO:0033036 252 0.012
axis specification GO:0009798 4 0.012
development of primary sexual characteristics GO:0045137 107 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
organic hydroxy compound transport GO:0015850 77 0.012
regulation of body fluid levels GO:0050878 90 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
single organism organelle organization GO:1902589 180 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
Rat
brain development GO:0007420 247 0.012
Rat Fly
cyclic nucleotide biosynthetic process GO:0009190 63 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
cellular response to starvation GO:0009267 27 0.011
gastrulation GO:0007369 2 0.011
negative regulation of protein processing GO:0010955 47 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of dendrite development GO:0050773 59 0.011
carboxylic acid transport GO:0046942 115 0.011
cellular response to ketone GO:1901655 51 0.011
Rat
cellular response to metal ion GO:0071248 55 0.011
bile acid biosynthetic process GO:0006699 3 0.011
cellular response to oxidative stress GO:0034599 76 0.011
Rat
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
response to ketone GO:1901654 182 0.011
Rat
acute inflammatory response GO:0002526 58 0.011
regulation of secretion GO:0051046 224 0.011
positive regulation of catabolic process GO:0009896 78 0.011
protein complex assembly GO:0006461 263 0.011
cellular catabolic process GO:0044248 295 0.011
Human
positive regulation of secretion by cell GO:1903532 128 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
Rat
maintenance of location GO:0051235 17 0.011
leukocyte activation GO:0045321 76 0.010
muscle contraction GO:0006936 88 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
intracellular transport GO:0046907 185 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
response to growth factor GO:0070848 189 0.010
regulation of calcium ion transport GO:0051924 77 0.010
protein complex biogenesis GO:0070271 263 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
cytoplasmic transport GO:0016482 115 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
response to radiation GO:0009314 137 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
response to toxic substance GO:0009636 133 0.010
inflammatory response GO:0006954 150 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010

Akr1b7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
urinary system disease DOID:18 0 0.030
disease of metabolism DOID:0014667 0 0.021
sensory system disease DOID:0050155 0 0.019
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
inherited metabolic disorder DOID:655 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010