Rattus norvegicus

27 known processes

Akr7a3

aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)

(Aliases: Akr7a1,Afar)

Akr7a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chlorinated hydrocarbon metabolic process GO:0042196 4 0.402
response to inorganic substance GO:0010035 377 0.254
cellular response to lipid GO:0071396 201 0.193
cellular response to peptide GO:1901653 133 0.187
response to acid chemical GO:0001101 222 0.182
carboxylic acid metabolic process GO:0019752 289 0.172
organic acid metabolic process GO:0006082 292 0.169
response to corticosteroid GO:0031960 235 0.168
cellular response to hormone stimulus GO:0032870 247 0.149
cellular amino acid metabolic process GO:0006520 107 0.143
oxoacid metabolic process GO:0043436 290 0.141
cellular component assembly GO:0022607 360 0.140
response to nutrient GO:0007584 248 0.139
response to nutrient levels GO:0031667 370 0.129
response to carbohydrate GO:0009743 183 0.119
cellular response to peptide hormone stimulus GO:0071375 120 0.116
response to glucocorticoid GO:0051384 223 0.114
cellular response to endogenous stimulus GO:0071495 377 0.113
monocarboxylic acid metabolic process GO:0032787 152 0.111
cellular response to oxygen containing compound GO:1901701 386 0.109
response to xenobiotic stimulus GO:0009410 23 0.106
response to biotic stimulus GO:0009607 226 0.105
response to hypoxia GO:0001666 231 0.104
response to ethanol GO:0045471 162 0.104
response to transition metal nanoparticle GO:1990267 122 0.102
cellular catabolic process GO:0044248 295 0.101
response to metal ion GO:0010038 253 0.101
cellular response to steroid hormone stimulus GO:0071383 93 0.100
xenobiotic catabolic process GO:0042178 7 0.098
response to external biotic stimulus GO:0043207 221 0.097
liver development GO:0001889 90 0.093
response to extracellular stimulus GO:0009991 380 0.093
response to estrogen GO:0043627 232 0.093
regulation of apoptotic process GO:0042981 335 0.092
cellular response to organic cyclic compound GO:0071407 202 0.082
cellular response to nitrogen compound GO:1901699 210 0.081
hepaticobiliary system development GO:0061008 90 0.079
response to insulin GO:0032868 133 0.079
response to lipopolysaccharide GO:0032496 191 0.078
cellular response to organonitrogen compound GO:0071417 197 0.075
aging GO:0007568 241 0.075
cellular amide metabolic process GO:0043603 44 0.073
regulation of molecular function GO:0065009 398 0.072
organic anion transport GO:0015711 132 0.070
gland development GO:0048732 155 0.070
secretion by cell GO:0032940 248 0.068
regulation of programmed cell death GO:0043067 341 0.067
response to bacterium GO:0009617 200 0.065
cellular component biogenesis GO:0044085 368 0.065
catabolic process GO:0009056 351 0.063
response to peptide GO:1901652 292 0.063
lipid metabolic process GO:0006629 283 0.063
response to toxic substance GO:0009636 133 0.062
apoptotic process GO:0006915 381 0.061
macromolecular complex subunit organization GO:0043933 339 0.060
central nervous system development GO:0007417 311 0.060
protein complex assembly GO:0006461 263 0.060
cellular response to insulin stimulus GO:0032869 81 0.059
negative regulation of metabolic process GO:0009892 331 0.059
single organism biosynthetic process GO:0044711 342 0.059
organelle organization GO:0006996 266 0.059
multi organism reproductive process GO:0044703 262 0.059
response to wounding GO:0009611 254 0.057
anatomical structure morphogenesis GO:0009653 298 0.057
response to other organism GO:0051707 220 0.057
response to peptide hormone GO:0043434 278 0.056
cellular modified amino acid metabolic process GO:0006575 61 0.056
cellular response to glucocorticoid stimulus GO:0071385 68 0.054
fatty acid metabolic process GO:0006631 99 0.053
halogenated hydrocarbon metabolic process GO:0042197 4 0.052
response to estradiol GO:0032355 164 0.051
response to oxidative stress GO:0006979 186 0.048
response to vitamin GO:0033273 131 0.048
organic acid biosynthetic process GO:0016053 83 0.048
vesicle mediated transport GO:0016192 181 0.048
protein complex subunit organization GO:0071822 302 0.047
single organism organelle organization GO:1902589 180 0.046
cellular lipid metabolic process GO:0044255 208 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
negative regulation of apoptotic process GO:0043066 181 0.044
secretion GO:0046903 307 0.044
organonitrogen compound biosynthetic process GO:1901566 167 0.043
tissue development GO:0009888 252 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.042
response to nicotine GO:0035094 51 0.041
response to monosaccharide GO:0034284 159 0.041
protein oligomerization GO:0051259 191 0.041
response to ketone GO:1901654 182 0.040
neurological system process GO:0050877 219 0.040
rna biosynthetic process GO:0032774 380 0.040
gliogenesis GO:0042063 93 0.040
anion transport GO:0006820 178 0.039
protein complex biogenesis GO:0070271 263 0.039
insecticide metabolic process GO:0017143 4 0.038
alkaloid metabolic process GO:0009820 3 0.038
circulatory system process GO:0003013 183 0.037
response to oxygen levels GO:0070482 265 0.037
macromolecular complex assembly GO:0065003 273 0.037
glutathione metabolic process GO:0006749 15 0.037
neuron development GO:0048666 286 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
cellular ketone metabolic process GO:0042180 51 0.035
circadian rhythm GO:0007623 88 0.034
response to molecule of bacterial origin GO:0002237 194 0.034
transcription dna templated GO:0006351 377 0.034
behavior GO:0007610 205 0.034
response to radiation GO:0009314 137 0.034
response to amino acid GO:0043200 75 0.034
programmed cell death GO:0012501 392 0.033
response to alkaloid GO:0043279 132 0.032
intracellular signal transduction GO:0035556 314 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
response to decreased oxygen levels GO:0036293 237 0.032
cell part morphogenesis GO:0032990 123 0.031
organophosphate metabolic process GO:0019637 370 0.031
drug transmembrane transport GO:0006855 13 0.031
sulfur compound metabolic process GO:0006790 70 0.031
organ regeneration GO:0031100 101 0.031
cellular component morphogenesis GO:0032989 155 0.031
xenobiotic metabolic process GO:0006805 19 0.031
regulation of hormone levels GO:0010817 187 0.031
carboxylic acid biosynthetic process GO:0046394 83 0.031
regulation of blood vessel size GO:0050880 89 0.031
cell projection organization GO:0030030 302 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
sensory perception GO:0007600 101 0.030
response to testosterone GO:0033574 55 0.030
benzene containing compound metabolic process GO:0042537 22 0.030
response to herbicide GO:0009635 16 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
positive regulation of gene expression GO:0010628 244 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
cation transport GO:0006812 382 0.030
cellular modified amino acid biosynthetic process GO:0042398 18 0.029
regulation of rna metabolic process GO:0051252 391 0.029
negative regulation of programmed cell death GO:0043069 183 0.028
isoprenoid metabolic process GO:0006720 45 0.028
cell type specific apoptotic process GO:0097285 134 0.028
macromolecule localization GO:0033036 252 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
endocrine system development GO:0035270 30 0.027
response to growth factor GO:0070848 189 0.027
cellular response to external stimulus GO:0071496 118 0.027
response to epidermal growth factor GO:0070849 18 0.027
nitrogen compound transport GO:0071705 229 0.027
regulation of protein metabolic process GO:0051246 289 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
hormone transport GO:0009914 121 0.027
response to purine containing compound GO:0014074 126 0.026
pyridine containing compound metabolic process GO:0072524 32 0.026
peptide metabolic process GO:0006518 32 0.026
rna metabolic process GO:0016070 406 0.026
cellular response to corticosteroid stimulus GO:0071384 69 0.026
response to reactive oxygen species GO:0000302 120 0.026
oxidation reduction process GO:0055114 304 0.026
cellular response to stress GO:0033554 269 0.026
sodium independent organic anion transport GO:0043252 2 0.025
organic hydroxy compound metabolic process GO:1901615 115 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
regulation of signal transduction GO:0009966 318 0.025
terpenoid metabolic process GO:0006721 37 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
choline transport GO:0015871 4 0.024
response to retinoic acid GO:0032526 63 0.024
negative regulation of developmental process GO:0051093 125 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
protein phosphorylation GO:0006468 345 0.024
amino acid transport GO:0006865 70 0.024
response to cytokine GO:0034097 215 0.024
regulation of transcription dna templated GO:0006355 374 0.023
amine metabolic process GO:0009308 38 0.023
regeneration GO:0031099 163 0.023
single organism reproductive process GO:0044702 297 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of cellular component organization GO:0051128 368 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
regulation of tube size GO:0035150 89 0.022
response to hexose GO:0009746 144 0.022
protein autophosphorylation GO:0046777 66 0.022
single organism catabolic process GO:0044712 283 0.022
organic acid transport GO:0015849 116 0.022
negative regulation of cell death GO:0060548 229 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.021
regulation of catalytic activity GO:0050790 304 0.021
axis specification GO:0009798 4 0.021
neuron differentiation GO:0030182 368 0.021
regulation of cell differentiation GO:0045595 320 0.021
response to mercury ion GO:0046689 15 0.021
cellular chemical homeostasis GO:0055082 247 0.021
single organism behavior GO:0044708 130 0.021
nucleotide metabolic process GO:0009117 279 0.021
steroid metabolic process GO:0008202 73 0.021
organic substance catabolic process GO:1901575 316 0.021
rhythmic process GO:0048511 156 0.021
cell projection morphogenesis GO:0048858 123 0.020
carboxylic acid transport GO:0046942 115 0.020
homeostatic process GO:0042592 331 0.020
immune response GO:0006955 104 0.020
reproductive structure development GO:0048608 128 0.020
response to calcium ion GO:0051592 59 0.020
response to organophosphorus GO:0046683 102 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
regulation of anatomical structure size GO:0090066 135 0.020
regulation of membrane potential GO:0042391 110 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
positive regulation of transport GO:0051050 245 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.019
glial cell development GO:0021782 19 0.019
neuron projection morphogenesis GO:0048812 122 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
cellular response to ketone GO:1901655 51 0.019
head development GO:0060322 247 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
response to temperature stimulus GO:0009266 94 0.019
negative regulation of gene expression GO:0010629 199 0.019
response to tumor necrosis factor GO:0034612 56 0.019
aromatic compound catabolic process GO:0019439 168 0.019
ion transmembrane transport GO:0034220 365 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
secondary metabolite catabolic process GO:0090487 1 0.019
regulation of neuron differentiation GO:0045664 208 0.019
developmental process involved in reproduction GO:0003006 159 0.019
linoleic acid metabolic process GO:0043651 4 0.018
neuron apoptotic process GO:0051402 88 0.018
vascular process in circulatory system GO:0003018 96 0.018
glial cell differentiation GO:0010001 65 0.018
regulation of cellular localization GO:0060341 263 0.018
cation transmembrane transport GO:0098655 263 0.018
gastrulation GO:0007369 2 0.018
neuron projection development GO:0031175 273 0.018
cell cycle GO:0007049 101 0.018
reproductive process GO:0022414 372 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
cognition GO:0050890 92 0.018
positive regulation of cell communication GO:0010647 271 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
response to glucose GO:0009749 136 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
embryonic pattern specification GO:0009880 1 0.018
amide transport GO:0042886 105 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
chemical homeostasis GO:0048878 292 0.018
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.018
lipid localization GO:0010876 62 0.017
defense response GO:0006952 194 0.017
metal ion transport GO:0030001 289 0.017
coenzyme metabolic process GO:0006732 86 0.017
response to l ascorbic acid GO:0033591 15 0.017
cellular response to xenobiotic stimulus GO:0071466 19 0.017
heterocycle catabolic process GO:0046700 167 0.017
cellular response to epidermal growth factor stimulus GO:0071364 12 0.017
cellular response to alcohol GO:0097306 87 0.017
monocarboxylic acid transport GO:0015718 52 0.017
action potential GO:0001508 54 0.017
serine family amino acid catabolic process GO:0009071 3 0.017
positive regulation of signaling GO:0023056 270 0.017
learning or memory GO:0007611 90 0.017
muscle system process GO:0003012 115 0.017
growth GO:0040007 165 0.017
localization of cell GO:0051674 202 0.017
regulation of secretion GO:0051046 224 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
purine containing compound metabolic process GO:0072521 253 0.016
learning GO:0007612 33 0.016
response to ionizing radiation GO:0010212 59 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
mesoderm development GO:0007498 2 0.016
cellular amino acid biosynthetic process GO:0008652 32 0.016
negative regulation of cell communication GO:0010648 158 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
nucleic acid templated transcription GO:0097659 379 0.016
single organism intracellular transport GO:1902582 166 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
regulation of ion transport GO:0043269 245 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
reproductive system development GO:0061458 128 0.016
regulation of inflammatory response GO:0050727 48 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
cellular protein localization GO:0034613 122 0.016
heart morphogenesis GO:0003007 3 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of organelle organization GO:0033043 80 0.016
antibiotic transport GO:0042891 2 0.016
immune system process GO:0002376 204 0.016
endocytosis GO:0006897 84 0.015
unsaturated fatty acid metabolic process GO:0033559 39 0.015
regulation of nervous system development GO:0051960 264 0.015
regulation of cell cycle GO:0051726 73 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
epithelial cell differentiation GO:0030855 71 0.015
transmission of nerve impulse GO:0019226 42 0.015
cellular response to testosterone stimulus GO:0071394 5 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
cellular response to vitamin e GO:0071306 3 0.015
peptide biosynthetic process GO:0043043 3 0.015
multicellular organism reproduction GO:0032504 233 0.015
regulation of system process GO:0044057 208 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
dopamine metabolic process GO:0042417 12 0.015
reproduction GO:0000003 245 0.015
actin filament based process GO:0030029 86 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
chemosensory behavior GO:0007635 2 0.015
blood circulation GO:0008015 183 0.015
synaptic transmission GO:0007268 235 0.015
protein homooligomerization GO:0051260 91 0.015
signal release GO:0023061 145 0.015
regulation of response to stress GO:0080134 126 0.015
naphthalene containing compound metabolic process GO:0090420 2 0.015
multi multicellular organism process GO:0044706 138 0.015
brain development GO:0007420 247 0.015
multicellular organism growth GO:0035264 1 0.014
cellular ion homeostasis GO:0006873 184 0.014
regulation of catabolic process GO:0009894 113 0.014
regulation of neurogenesis GO:0050767 247 0.014
phenol containing compound metabolic process GO:0018958 30 0.014
response to hydrogen peroxide GO:0042542 89 0.014
carboxylic acid catabolic process GO:0046395 49 0.014
urogenital system development GO:0001655 78 0.014
regulation of cell development GO:0060284 263 0.014
nonribosomal peptide biosynthetic process GO:0019184 3 0.014
toxin catabolic process GO:0009407 1 0.014
locomotion GO:0040011 237 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
negative regulation of signaling GO:0023057 157 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
cellular response to metal ion GO:0071248 55 0.013
naphthalene metabolic process GO:0018931 2 0.013
icosanoid metabolic process GO:0006690 38 0.013
modified amino acid transport GO:0072337 12 0.013
sexual reproduction GO:0019953 148 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
cellular component movement GO:0006928 248 0.013
cofactor biosynthetic process GO:0051188 28 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
organophosphate catabolic process GO:0046434 148 0.013
cofactor metabolic process GO:0051186 95 0.013
cellular homeostasis GO:0019725 252 0.013
organic acid catabolic process GO:0016054 49 0.013
cellular macromolecule localization GO:0070727 122 0.013
cell cycle checkpoint GO:0000075 2 0.013
regulation of phosphorylation GO:0042325 248 0.013
response to lithium ion GO:0010226 28 0.013
retinoid metabolic process GO:0001523 24 0.013
intracellular transport GO:0046907 185 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
positive regulation of secretion GO:0051047 140 0.013
cell migration GO:0016477 197 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
membrane organization GO:0061024 94 0.012
response to zinc ion GO:0010043 39 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
positive regulation of mitochondrion organization GO:0010822 4 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
positive regulation of cell motility GO:2000147 97 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
response to lead ion GO:0010288 33 0.012
lipid storage GO:0019915 1 0.012
gamete generation GO:0007276 124 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cytoskeleton organization GO:0007010 111 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
regulation of response to wounding GO:1903034 69 0.012
ras protein signal transduction GO:0007265 29 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
regulation of cell migration GO:0030334 128 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cellular response to acid chemical GO:0071229 75 0.012
development of primary sexual characteristics GO:0045137 107 0.012
response to molecule of fungal origin GO:0002238 3 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
glutathione biosynthetic process GO:0006750 3 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
response to camp GO:0051591 91 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of blood pressure GO:0008217 83 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
positive regulation of ion transport GO:0043270 94 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
lipid biosynthetic process GO:0008610 128 0.011
response to axon injury GO:0048678 59 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of blood circulation GO:1903522 110 0.011
transmembrane transport GO:0055085 412 0.011
regulation of secretion by cell GO:1903530 208 0.011
positive regulation of molecular function GO:0044093 230 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
neurotrophin production GO:0032898 2 0.011
fatty acid derivative metabolic process GO:1901568 38 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of developmental process GO:0051094 283 0.011
hormone secretion GO:0046879 115 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
inflammatory response GO:0006954 150 0.011
porphyrin containing compound metabolic process GO:0006778 8 0.011
regulation of protein modification process GO:0031399 194 0.011
eye morphogenesis GO:0048592 4 0.011
response to starvation GO:0042594 59 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of cell differentiation GO:0045597 217 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular response to oxidative stress GO:0034599 76 0.010
ion homeostasis GO:0050801 212 0.010
positive regulation of response to wounding GO:1903036 34 0.010
long chain fatty acid metabolic process GO:0001676 32 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
catecholamine metabolic process GO:0006584 19 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
positive regulation of neuron apoptotic process GO:0043525 33 0.010
toxin metabolic process GO:0009404 9 0.010
cellular response to dexamethasone stimulus GO:0071549 36 0.010
cell cell signaling GO:0007267 335 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
organic hydroxy compound transport GO:0015850 77 0.010
organic cation transport GO:0015695 11 0.010
tetrapyrrole metabolic process GO:0033013 11 0.010

Akr7a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
cardiovascular system disease DOID:1287 0 0.023
hypertension DOID:10763 0 0.023
artery disease DOID:0050828 0 0.023
essential hypertension DOID:10825 0 0.023
vascular disease DOID:178 0 0.023
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.011
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011