Rattus norvegicus

0 known processes

Aktip

AKT interacting protein

(Aliases: Fts,MGC109405)

Aktip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of protein localization GO:0045184 141 0.228
regulation of cell proliferation GO:0042127 359 0.207
single organism intracellular transport GO:1902582 166 0.193
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.182
regulation of phosphate metabolic process GO:0019220 349 0.181
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.181
cellular amino acid metabolic process GO:0006520 107 0.178
regulation of phosphorylation GO:0042325 248 0.171
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.152
negative regulation of metabolic process GO:0009892 331 0.136
protein localization GO:0008104 191 0.132
regulation of rna metabolic process GO:0051252 391 0.131
regulation of phosphorus metabolic process GO:0051174 349 0.117
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.114
organophosphate metabolic process GO:0019637 370 0.114
protein targeting GO:0006605 61 0.110
intracellular signal transduction GO:0035556 314 0.107
vesicle mediated transport GO:0016192 181 0.106
Human
purine containing compound metabolic process GO:0072521 253 0.099
macromolecule localization GO:0033036 252 0.098
cellular catabolic process GO:0044248 295 0.094
cellular protein localization GO:0034613 122 0.092
regulation of rna biosynthetic process GO:2001141 381 0.090
organic acid metabolic process GO:0006082 292 0.090
transcription dna templated GO:0006351 377 0.089
regulation of cellular component organization GO:0051128 368 0.088
positive regulation of phosphorus metabolic process GO:0010562 262 0.083
Human
secretion by cell GO:0032940 248 0.080
cell cell signaling GO:0007267 335 0.079
rna metabolic process GO:0016070 406 0.073
oxoacid metabolic process GO:0043436 290 0.072
single organism biosynthetic process GO:0044711 342 0.072
homeostatic process GO:0042592 331 0.072
negative regulation of cellular metabolic process GO:0031324 281 0.067
regulation of intracellular signal transduction GO:1902531 218 0.063
intracellular transport GO:0046907 185 0.063
Human
regulation of hydrolase activity GO:0051336 143 0.063
regulation of transcription dna templated GO:0006355 374 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
macromolecular complex subunit organization GO:0043933 339 0.061
carbohydrate derivative metabolic process GO:1901135 346 0.061
cellular macromolecule localization GO:0070727 122 0.059
amp metabolic process GO:0046033 8 0.058
protein transport GO:0015031 132 0.058
secretion GO:0046903 307 0.057
glycosyl compound metabolic process GO:1901657 182 0.057
positive regulation of phosphate metabolic process GO:0045937 262 0.057
Human
intracellular protein transport GO:0006886 79 0.055
positive regulation of biosynthetic process GO:0009891 319 0.054
negative regulation of cell proliferation GO:0008285 119 0.053
carboxylic acid metabolic process GO:0019752 289 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.053
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.052
cellular ketone metabolic process GO:0042180 51 0.052
purine nucleotide metabolic process GO:0006163 229 0.051
positive regulation of rna biosynthetic process GO:1902680 197 0.051
cell projection organization GO:0030030 302 0.051
cellular amino acid catabolic process GO:0009063 21 0.050
regulation of cellular protein metabolic process GO:0032268 267 0.050
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.050
positive regulation of nucleic acid templated transcription GO:1903508 197 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.049
nucleoside phosphate metabolic process GO:0006753 283 0.048
regulation of protein metabolic process GO:0051246 289 0.048
Human
ribonucleoside metabolic process GO:0009119 174 0.047
purine nucleoside metabolic process GO:0042278 169 0.047
muscle cell proliferation GO:0033002 84 0.047
cellular calcium ion homeostasis GO:0006874 160 0.046
protein complex subunit organization GO:0071822 302 0.046
nucleic acid templated transcription GO:0097659 379 0.045
nucleoside metabolic process GO:0009116 179 0.044
positive regulation of transcription dna templated GO:0045893 197 0.044
negative regulation of molecular function GO:0044092 133 0.044
programmed cell death GO:0012501 392 0.044
regulation of protein phosphorylation GO:0001932 183 0.042
Human
cation transport GO:0006812 382 0.042
regulation of molecular function GO:0065009 398 0.042
Human
organelle organization GO:0006996 266 0.042
Human
catabolic process GO:0009056 351 0.041
regulation of catalytic activity GO:0050790 304 0.041
organic substance catabolic process GO:1901575 316 0.040
ribonucleotide metabolic process GO:0009259 231 0.040
single organism membrane organization GO:0044802 74 0.039
aging GO:0007568 241 0.039
organophosphate biosynthetic process GO:0090407 143 0.039
regulation of anatomical structure size GO:0090066 135 0.038
negative regulation of protein metabolic process GO:0051248 114 0.038
cellular divalent inorganic cation homeostasis GO:0072503 162 0.038
nucleotide metabolic process GO:0009117 279 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.037
cellular ion homeostasis GO:0006873 184 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
positive regulation of cell communication GO:0010647 271 0.036
mitotic spindle organization GO:0007052 2 0.036
organonitrogen compound catabolic process GO:1901565 179 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
Fly
nucleoside triphosphate metabolic process GO:0009141 144 0.035
endomembrane system organization GO:0010256 48 0.035
Human
single organism organelle organization GO:1902589 180 0.035
response to radiation GO:0009314 137 0.035
cell cycle GO:0007049 101 0.035
regulation of secretion GO:0051046 224 0.034
early endosome to late endosome transport GO:0045022 2 0.034
Human
amine metabolic process GO:0009308 38 0.034
regulation of signal transduction GO:0009966 318 0.033
cellular chemical homeostasis GO:0055082 247 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
Human
negative regulation of transport GO:0051051 136 0.033
purine ribonucleoside metabolic process GO:0046128 168 0.033
regulation of cellular component movement GO:0051270 150 0.033
regulation of apoptotic process GO:0042981 335 0.033
protein phosphorylation GO:0006468 345 0.032
Human
regulation of programmed cell death GO:0043067 341 0.032
positive regulation of transport GO:0051050 245 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
Human
ion homeostasis GO:0050801 212 0.032
purine ribonucleotide metabolic process GO:0009150 227 0.031
dephosphorylation GO:0016311 98 0.031
regulation of cell motility GO:2000145 131 0.031
response to nutrient GO:0007584 248 0.030
monocarboxylic acid metabolic process GO:0032787 152 0.030
positive regulation of ion transport GO:0043270 94 0.030
apoptotic process GO:0006915 381 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
regulation of membrane potential GO:0042391 110 0.030
synaptic growth at neuromuscular junction GO:0051124 1 0.029
protein localization to organelle GO:0033365 57 0.029
cytoplasmic transport GO:0016482 115 0.029
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
metal ion transport GO:0030001 289 0.028
negative regulation of cell death GO:0060548 229 0.028
regulation of system process GO:0044057 208 0.028
behavior GO:0007610 205 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
nitrogen compound transport GO:0071705 229 0.027
cellular response to stress GO:0033554 269 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
Human
chemical homeostasis GO:0048878 292 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
positive regulation of gene expression GO:0010628 244 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.026
peptide transport GO:0015833 97 0.026
divalent inorganic cation homeostasis GO:0072507 165 0.026
cation homeostasis GO:0055080 195 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
response to wounding GO:0009611 254 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
single organism cellular localization GO:1902580 102 0.026
response to extracellular stimulus GO:0009991 380 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
negative regulation of cellular protein metabolic process GO:0032269 106 0.025
smooth muscle cell proliferation GO:0048659 77 0.025
protein complex assembly GO:0006461 263 0.025
rna biosynthetic process GO:0032774 380 0.025
neurological system process GO:0050877 219 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
proteolysis GO:0006508 175 0.025
positive regulation of signal transduction GO:0009967 175 0.025
positive regulation of secretion GO:0051047 140 0.025
positive regulation of signaling GO:0023056 270 0.025
response to estrogen GO:0043627 232 0.024
response to nutrient levels GO:0031667 370 0.024
ras protein signal transduction GO:0007265 29 0.024
small molecule biosynthetic process GO:0044283 124 0.024
single organism catabolic process GO:0044712 283 0.024
metal ion homeostasis GO:0055065 186 0.024
cellular amine metabolic process GO:0044106 38 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
multicellular organismal signaling GO:0035637 44 0.024
regulation of establishment of protein localization GO:0070201 69 0.024
negative regulation of transcription dna templated GO:0045892 116 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
cellular modified amino acid metabolic process GO:0006575 61 0.023
fatty acid metabolic process GO:0006631 99 0.023
immune system process GO:0002376 204 0.023
regulation of body fluid levels GO:0050878 90 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
regulation of protein modification process GO:0031399 194 0.023
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
positive regulation of rna metabolic process GO:0051254 203 0.022
endocytosis GO:0006897 84 0.022
phosphatidylinositol dephosphorylation GO:0046856 4 0.022
regeneration GO:0031099 163 0.022
alpha amino acid metabolic process GO:1901605 71 0.022
regulation of peptide transport GO:0090087 87 0.022
regulation of locomotion GO:0040012 148 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
cell migration GO:0016477 197 0.022
multi organism reproductive process GO:0044703 262 0.022
Fly
neuron projection development GO:0031175 273 0.022
membrane organization GO:0061024 94 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
regulation of vesicle mediated transport GO:0060627 81 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
response to peptide GO:1901652 292 0.021
positive regulation of cell death GO:0010942 184 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
calcium ion homeostasis GO:0055074 162 0.020
regulation of cellular localization GO:0060341 263 0.020
response to growth factor GO:0070848 189 0.020
reproductive process GO:0022414 372 0.020
Fly
regulation of multicellular organismal development GO:2000026 376 0.020
growth GO:0040007 165 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
negative regulation of catalytic activity GO:0043086 103 0.020
amide transport GO:0042886 105 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
positive regulation of locomotion GO:0040017 102 0.019
protein localization to membrane GO:0072657 36 0.019
regulation of response to external stimulus GO:0032101 106 0.019
regulation of metal ion transport GO:0010959 118 0.019
alpha amino acid catabolic process GO:1901606 20 0.019
macromolecular complex assembly GO:0065003 273 0.018
central nervous system development GO:0007417 311 0.018
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.018
cellular homeostasis GO:0019725 252 0.018
cytoskeleton organization GO:0007010 111 0.018
endosomal transport GO:0016197 14 0.018
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
gland development GO:0048732 155 0.018
cellular cation homeostasis GO:0030003 180 0.018
developmental growth GO:0048589 100 0.018
regulation of response to stress GO:0080134 126 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
axon development GO:0061564 96 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
Fly
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
neuron death GO:0070997 127 0.017
purine containing compound catabolic process GO:0072523 138 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
localization of cell GO:0051674 202 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
regulation of blood pressure GO:0008217 83 0.017
rhythmic process GO:0048511 156 0.017
cell growth GO:0016049 104 0.017
synaptic transmission GO:0007268 235 0.017
cellular lipid metabolic process GO:0044255 208 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
regulation of synaptic transmission GO:0050804 141 0.016
protein complex biogenesis GO:0070271 263 0.016
cellular component assembly GO:0022607 360 0.016
positive regulation of developmental process GO:0051094 283 0.016
protein processing GO:0016485 68 0.016
regulation of ion transport GO:0043269 245 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
negative regulation of gene expression GO:0010629 199 0.016
regulation of cellular response to stress GO:0080135 49 0.016
cellular response to topologically incorrect protein GO:0035967 3 0.016
single organism reproductive process GO:0044702 297 0.016
Fly
glycosyl compound catabolic process GO:1901658 126 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
axon cargo transport GO:0008088 1 0.016
response to inorganic substance GO:0010035 377 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
neuron differentiation GO:0030182 368 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
response to oxidative stress GO:0006979 186 0.015
cellular component biogenesis GO:0044085 368 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
circulatory system development GO:0072359 134 0.015
small molecule catabolic process GO:0044282 59 0.015
regulation of cell cycle GO:0051726 73 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
carboxylic acid catabolic process GO:0046395 49 0.014
positive regulation of protein modification process GO:0031401 142 0.014
Human
positive regulation of hydrolase activity GO:0051345 86 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
organ regeneration GO:0031100 101 0.014
locomotion GO:0040011 237 0.014
ion transmembrane transport GO:0034220 365 0.014
chromosome segregation GO:0007059 2 0.014
muscle system process GO:0003012 115 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of cell size GO:0008361 37 0.014
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
spindle organization GO:0007051 2 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of secretion by cell GO:1903530 208 0.014
ribose phosphate biosynthetic process GO:0046390 87 0.014
negative regulation of cell communication GO:0010648 158 0.014
bmp signaling pathway GO:0030509 4 0.014
regulation of catabolic process GO:0009894 113 0.013
sulfur amino acid metabolic process GO:0000096 9 0.013
positive regulation of molecular function GO:0044093 230 0.013
Human
cellular modified amino acid catabolic process GO:0042219 1 0.013
neuron development GO:0048666 286 0.013
positive regulation of cell motility GO:2000147 97 0.013
transmembrane transport GO:0055085 412 0.013
potassium ion transport GO:0006813 97 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
neuronal action potential GO:0019228 35 0.013
organic acid catabolic process GO:0016054 49 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
Human
negative regulation of signaling GO:0023057 157 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
regulation of growth GO:0040008 105 0.013
unsaturated fatty acid metabolic process GO:0033559 39 0.013
response to mechanical stimulus GO:0009612 134 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of signal transduction GO:0009968 83 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to toxic substance GO:0009636 133 0.012
endosome to lysosome transport GO:0008333 6 0.012
Human
positive regulation of cell migration GO:0030335 96 0.012
response to peptide hormone GO:0043434 278 0.012
reproduction GO:0000003 245 0.012
Fly
regulation of neurological system process GO:0031644 43 0.012
divalent inorganic cation transport GO:0072511 134 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
brain development GO:0007420 247 0.012
sexual reproduction GO:0019953 148 0.012
Fly
purine ribonucleotide catabolic process GO:0009154 136 0.012
response to cytokine GO:0034097 215 0.012
establishment of protein localization to membrane GO:0090150 16 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
peptidyl amino acid modification GO:0018193 126 0.012
purine nucleoside biosynthetic process GO:0042451 21 0.012
deoxyribose phosphate metabolic process GO:0019692 9 0.012
response to light stimulus GO:0009416 52 0.012
mapk cascade GO:0000165 140 0.012
golgi vesicle transport GO:0048193 22 0.012
regulation of homeostatic process GO:0032844 101 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
antigen processing and presentation GO:0019882 2 0.011
response to estradiol GO:0032355 164 0.011
multi multicellular organism process GO:0044706 138 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
regulation of cell differentiation GO:0045595 320 0.011
microtubule organizing center organization GO:0031023 1 0.011
female pregnancy GO:0007565 122 0.011
response to corticosteroid GO:0031960 235 0.011
positive regulation of cell development GO:0010720 176 0.011
endosome organization GO:0007032 3 0.011
Human
maintenance of location GO:0051235 17 0.011
dna metabolic process GO:0006259 96 0.011
response to insulin GO:0032868 133 0.011
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.011
deoxyribonucleoside triphosphate metabolic process GO:0009200 6 0.011
action potential GO:0001508 54 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
sodium ion transport GO:0006814 82 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
purine ribonucleoside biosynthetic process GO:0046129 21 0.011
tissue development GO:0009888 252 0.011
cellular modified amino acid biosynthetic process GO:0042398 18 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
response to decreased oxygen levels GO:0036293 237 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of mapk cascade GO:0043408 116 0.011
regulation of neuron death GO:1901214 115 0.011
gamete generation GO:0007276 124 0.011
Fly
organic acid biosynthetic process GO:0016053 83 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
response to hypoxia GO:0001666 231 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
centrosome organization GO:0051297 1 0.011
regulation of hormone levels GO:0010817 187 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
nucleoside catabolic process GO:0009164 126 0.010
regulation of nervous system development GO:0051960 264 0.010
regulation of neurogenesis GO:0050767 247 0.010
vasculature development GO:0001944 70 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
response to vitamin GO:0033273 131 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.010
heterocycle catabolic process GO:0046700 167 0.010
peptide secretion GO:0002790 86 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
cell activation GO:0001775 97 0.010
fatty acid derivative metabolic process GO:1901568 38 0.010
catecholamine secretion GO:0050432 33 0.010
cellular component movement GO:0006928 248 0.010
hormone transport GO:0009914 121 0.010
negative regulation of protein modification process GO:0031400 52 0.010

Aktip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049
sensory system disease DOID:0050155 0 0.021
neuropathy DOID:870 0 0.019
neuromuscular disease DOID:440 0 0.015
usher syndrome DOID:0050439 0 0.013
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.012