Rattus norvegicus

76 known processes

Aldh2

aldehyde dehydrogenase 2 family (mitochondrial)

Aldh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.441
Rat
carboxylic acid metabolic process GO:0019752 289 0.347
Yeast Rat
cellular response to stress GO:0033554 269 0.222
response to metal ion GO:0010038 253 0.218
oxidation reduction process GO:0055114 304 0.204
response to inorganic substance GO:0010035 377 0.185
catabolic process GO:0009056 351 0.172
Yeast
localization of cell GO:0051674 202 0.118
organic acid metabolic process GO:0006082 292 0.116
Yeast Rat
cellular amino acid metabolic process GO:0006520 107 0.097
Yeast
single organism catabolic process GO:0044712 283 0.090
response to genistein GO:0033595 4 0.090
response to glucocorticoid GO:0051384 223 0.088
programmed cell death GO:0012501 392 0.087
cellular amino acid catabolic process GO:0009063 21 0.086
oxoacid metabolic process GO:0043436 290 0.084
Yeast Rat
response to wounding GO:0009611 254 0.082
regulation of neurogenesis GO:0050767 247 0.081
positive regulation of developmental process GO:0051094 283 0.072
cellular component movement GO:0006928 248 0.072
gland development GO:0048732 155 0.068
response to corticosteroid GO:0031960 235 0.068
cell projection organization GO:0030030 302 0.067
regulation of nervous system development GO:0051960 264 0.066
regulation of cellular component movement GO:0051270 150 0.061
positive regulation of nervous system development GO:0051962 178 0.060
neuron differentiation GO:0030182 368 0.056
response to extracellular stimulus GO:0009991 380 0.055
Rat
cation transport GO:0006812 382 0.053
dendrite development GO:0016358 72 0.052
cellular response to hormone stimulus GO:0032870 247 0.048
cell migration GO:0016477 197 0.046
regulation of phosphorylation GO:0042325 248 0.046
protein phosphorylation GO:0006468 345 0.045
macromolecular complex subunit organization GO:0043933 339 0.042
Rat
regulation of cell migration GO:0030334 128 0.042
cellular lipid catabolic process GO:0044242 37 0.042
response to organophosphorus GO:0046683 102 0.041
sulfur compound metabolic process GO:0006790 70 0.041
response to lead ion GO:0010288 33 0.040
regulation of cell development GO:0060284 263 0.040
response to catechin GO:1902168 1 0.040
alpha amino acid catabolic process GO:1901606 20 0.039
cellular catabolic process GO:0044248 295 0.039
branched chain amino acid catabolic process GO:0009083 4 0.038
chemical homeostasis GO:0048878 292 0.038
organic substance catabolic process GO:1901575 316 0.038
Yeast
cellular component biogenesis GO:0044085 368 0.038
Rat
intracellular signal transduction GO:0035556 314 0.037
protein complex subunit organization GO:0071822 302 0.037
Rat
anatomical structure morphogenesis GO:0009653 298 0.037
thioester biosynthetic process GO:0035384 7 0.037
positive regulation of neurogenesis GO:0050769 165 0.035
positive regulation of cell death GO:0010942 184 0.034
neuron development GO:0048666 286 0.034
wound healing GO:0042060 122 0.034
chromosome segregation GO:0007059 2 0.034
apoptotic process GO:0006915 381 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
regulation of cell projection organization GO:0031344 175 0.033
carboxylic acid catabolic process GO:0046395 49 0.033
behavior GO:0007610 205 0.033
cellular response to organic cyclic compound GO:0071407 202 0.033
cellular homeostasis GO:0019725 252 0.032
positive regulation of cell development GO:0010720 176 0.032
cellular response to peptide hormone stimulus GO:0071375 120 0.032
organonitrogen compound catabolic process GO:1901565 179 0.031
Yeast
regulation of intracellular signal transduction GO:1902531 218 0.031
lipid metabolic process GO:0006629 283 0.031
Rat
positive regulation of cellular component organization GO:0051130 200 0.031
cellular response to external stimulus GO:0071496 118 0.031
homeostatic process GO:0042592 331 0.030
response to aluminum ion GO:0010044 10 0.030
regulation of ion transport GO:0043269 245 0.029
negative regulation of signaling GO:0023057 157 0.029
locomotion GO:0040011 237 0.029
cellular response to peptide GO:1901653 133 0.029
cellular response to lipid GO:0071396 201 0.029
metal ion transport GO:0030001 289 0.029
monocarboxylic acid metabolic process GO:0032787 152 0.029
Yeast Rat
cell motility GO:0048870 202 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
nitrogen compound transport GO:0071705 229 0.028
rna metabolic process GO:0016070 406 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
ion homeostasis GO:0050801 212 0.027
response to axon injury GO:0048678 59 0.027
response to acid chemical GO:0001101 222 0.027
negative regulation of metabolic process GO:0009892 331 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
regulation of cell differentiation GO:0045595 320 0.026
cellular chemical homeostasis GO:0055082 247 0.026
macromolecular complex assembly GO:0065003 273 0.026
Rat
regulation of cell proliferation GO:0042127 359 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of signaling GO:0023056 270 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
organic acid catabolic process GO:0016054 49 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
lipid catabolic process GO:0016042 46 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of signal transduction GO:0009966 318 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
response to peptide GO:1901652 292 0.024
organic acid biosynthetic process GO:0016053 83 0.024
Yeast Rat
anion transmembrane transport GO:0098656 77 0.024
response to toxic substance GO:0009636 133 0.024
glycosyl compound metabolic process GO:1901657 182 0.023
response to camp GO:0051591 91 0.023
metal ion homeostasis GO:0055065 186 0.023
regulation of cellular component organization GO:0051128 368 0.023
organelle organization GO:0006996 266 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
protein complex biogenesis GO:0070271 263 0.023
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular response to oxidative stress GO:0034599 76 0.023
cellular response to organonitrogen compound GO:0071417 197 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
cytoskeleton organization GO:0007010 111 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of cellular response to stress GO:0080135 49 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
transmembrane transport GO:0055085 412 0.022
cellular ketone metabolic process GO:0042180 51 0.021
regulation of mapk cascade GO:0043408 116 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
neuron projection development GO:0031175 273 0.021
cation homeostasis GO:0055080 195 0.021
regulation of locomotion GO:0040012 148 0.021
response to purine containing compound GO:0014074 126 0.021
amine metabolic process GO:0009308 38 0.021
Yeast
regulation of protein modification process GO:0031399 194 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
cellular response to cytokine stimulus GO:0071345 127 0.020
cellular component assembly GO:0022607 360 0.020
Rat
cellular calcium ion homeostasis GO:0006874 160 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
protein complex assembly GO:0006461 263 0.020
Rat
fatty acid beta oxidation GO:0006635 22 0.020
response to hydrogen peroxide GO:0042542 89 0.020
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
small molecule biosynthetic process GO:0044283 124 0.019
Yeast Rat
regulation of cell motility GO:2000145 131 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
cell projection morphogenesis GO:0048858 123 0.019
regulation of rna metabolic process GO:0051252 391 0.019
skeletal system development GO:0001501 41 0.019
coenzyme metabolic process GO:0006732 86 0.019
Yeast
cellular amide metabolic process GO:0043603 44 0.018
response to cadmium ion GO:0046686 35 0.018
protein heterooligomerization GO:0051291 89 0.018
cofactor biosynthetic process GO:0051188 28 0.018
cellular amine metabolic process GO:0044106 38 0.018
Yeast
positive regulation of catalytic activity GO:0043085 184 0.018
acyl coa biosynthetic process GO:0071616 7 0.018
hair cycle process GO:0022405 2 0.018
phospholipid metabolic process GO:0006644 61 0.018
receptor localization to synapse GO:0097120 2 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
response to antibiotic GO:0046677 39 0.018
response to lipopolysaccharide GO:0032496 191 0.018
response to mechanical stimulus GO:0009612 134 0.018
muscle system process GO:0003012 115 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
regulation of multicellular organismal development GO:2000026 376 0.017
response to peptide hormone GO:0043434 278 0.017
response to lithium ion GO:0010226 28 0.017
response to cytokine GO:0034097 215 0.017
cellular modified amino acid metabolic process GO:0006575 61 0.017
anion transport GO:0006820 178 0.017
cellular ion homeostasis GO:0006873 184 0.017
response to nutrient GO:0007584 248 0.017
Rat
head development GO:0060322 247 0.017
Rat
sexual reproduction GO:0019953 148 0.017
ion transmembrane transport GO:0034220 365 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
positive regulation of molecular function GO:0044093 230 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
response to bacterium GO:0009617 200 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
positive regulation of gene expression GO:0010628 244 0.016
tissue development GO:0009888 252 0.016
renal system development GO:0072001 67 0.016
Rat
neurological system process GO:0050877 219 0.016
regulation of erk1 and erk2 cascade GO:0070372 41 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
nucleic acid templated transcription GO:0097659 379 0.016
rna biosynthetic process GO:0032774 380 0.016
protein oligomerization GO:0051259 191 0.016
Rat
acetyl coa metabolic process GO:0006084 17 0.016
nucleotide biosynthetic process GO:0009165 98 0.015
renal system process GO:0003014 40 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
hair follicle development GO:0001942 2 0.015
mapk cascade GO:0000165 140 0.015
cellular cation homeostasis GO:0030003 180 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of programmed cell death GO:0043067 341 0.015
transcription dna templated GO:0006351 377 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
negative regulation of cell communication GO:0010648 158 0.015
asymmetric protein localization GO:0008105 2 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
branched chain amino acid metabolic process GO:0009081 4 0.015
positive regulation of cell migration GO:0030335 96 0.015
actin cytoskeleton organization GO:0030036 73 0.015
calcium ion homeostasis GO:0055074 162 0.015
inorganic ion transmembrane transport GO:0098660 229 0.014
potassium ion transport GO:0006813 97 0.014
response to other organism GO:0051707 220 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
Yeast Rat
cellular response to nutrient levels GO:0031669 60 0.014
brain renin angiotensin system GO:0002035 3 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
negative regulation of signal transduction GO:0009968 83 0.014
neuron projection morphogenesis GO:0048812 122 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
chlorinated hydrocarbon metabolic process GO:0042196 4 0.014
cell communication involved in cardiac conduction GO:0086065 2 0.014
negative regulation of innate immune response GO:0045824 4 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
macromolecule localization GO:0033036 252 0.014
response to radiation GO:0009314 137 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
regulation of muscle system process GO:0090257 79 0.014
response to ketone GO:1901654 182 0.014
positive regulation of cell motility GO:2000147 97 0.014
benzene containing compound metabolic process GO:0042537 22 0.014
cellular component morphogenesis GO:0032989 155 0.013
multicellular organism reproduction GO:0032504 233 0.013
response to estrogen GO:0043627 232 0.013
protein homooligomerization GO:0051260 91 0.013
Rat
brain development GO:0007420 247 0.013
Rat
circulatory system process GO:0003013 183 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of molecular function GO:0065009 398 0.013
response to amino acid GO:0043200 75 0.013
actin filament based process GO:0030029 86 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
response to retinoic acid GO:0032526 63 0.013
Rat
regulation of lipid metabolic process GO:0019216 68 0.013
response to estradiol GO:0032355 164 0.013
purine containing compound metabolic process GO:0072521 253 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
positive regulation of locomotion GO:0040017 102 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
spindle organization GO:0007051 2 0.013
inflammatory response GO:0006954 150 0.013
sulfur compound biosynthetic process GO:0044272 19 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
gamete generation GO:0007276 124 0.012
cellular response to drug GO:0035690 30 0.012
Zebrafish
single organism reproductive process GO:0044702 297 0.012
response to oxidative stress GO:0006979 186 0.012
Rat
purine nucleotide metabolic process GO:0006163 229 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of metal ion transport GO:0010959 118 0.012
dephosphorylation GO:0016311 98 0.012
response to growth factor GO:0070848 189 0.012
central nervous system development GO:0007417 311 0.012
Rat
negative regulation of cell death GO:0060548 229 0.012
endoplasmic reticulum to cytosol transport GO:1903513 4 0.012
lipid storage GO:0019915 1 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cytoplasmic transport GO:0016482 115 0.012
response to starvation GO:0042594 59 0.012
organophosphate metabolic process GO:0019637 370 0.012
Yeast
positive regulation of immune system process GO:0002684 90 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to decreased oxygen levels GO:0036293 237 0.012
fatty acid metabolic process GO:0006631 99 0.012
establishment of tissue polarity GO:0007164 2 0.012
negative regulation of gene expression GO:0010629 199 0.012
positive regulation of protein modification process GO:0031401 142 0.012
single organism membrane organization GO:0044802 74 0.012
camp metabolic process GO:0046058 63 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of kinase activity GO:0043549 117 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
regulation of neuron differentiation GO:0045664 208 0.012
cellular protein localization GO:0034613 122 0.012
cardiac conduction GO:0061337 2 0.012
heart morphogenesis GO:0003007 3 0.012
cell part morphogenesis GO:0032990 123 0.011
ras protein signal transduction GO:0007265 29 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of membrane potential GO:0042391 110 0.011
reproduction GO:0000003 245 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
glutamine family amino acid metabolic process GO:0009064 15 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of immune system process GO:0002682 123 0.011
divalent inorganic cation transport GO:0072511 134 0.011
amide transport GO:0042886 105 0.011
dendrite morphogenesis GO:0048813 43 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
sensory organ development GO:0007423 74 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
multi organism reproductive process GO:0044703 262 0.011
molting cycle GO:0042303 3 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of transferase activity GO:0051347 81 0.011
lipid localization GO:0010876 62 0.011
regulation of system process GO:0044057 208 0.011
single organism intracellular transport GO:1902582 166 0.010
response to nitrosative stress GO:0051409 2 0.010
aging GO:0007568 241 0.010
nucleotide metabolic process GO:0009117 279 0.010
Yeast
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
cell morphogenesis GO:0000902 142 0.010
hair cycle GO:0042633 3 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
transmission of nerve impulse GO:0019226 42 0.010
single organism biosynthetic process GO:0044711 342 0.010
Yeast Rat
male gamete generation GO:0048232 99 0.010
regeneration GO:0031099 163 0.010
response to vitamin GO:0033273 131 0.010
Rat
organic hydroxy compound transport GO:0015850 77 0.010
regulation of catalytic activity GO:0050790 304 0.010
regulation of establishment of planar polarity GO:0090175 2 0.010

Aldh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
inherited metabolic disorder DOID:655 0 0.039
amino acid metabolic disorder DOID:9252 0 0.031
organic acidemia DOID:0060159 0 0.031
myopathy DOID:423 0 0.020
muscular disease DOID:0080000 0 0.020
heart disease DOID:114 0 0.020
cardiomyopathy DOID:0050700 0 0.020
disease of anatomical entity DOID:7 0 0.020
intrinsic cardiomyopathy DOID:0060036 0 0.020
cardiovascular system disease DOID:1287 0 0.020
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscle tissue disease DOID:66 0 0.020