Rattus norvegicus

54 known processes

Alox15

arachidonate 15-lipoxygenase

(Aliases: 12-LOX,Alox12l,Alox12)

Alox15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anion transport GO:0006820 178 0.254
cellular response to stress GO:0033554 269 0.203
Mouse
cellular component assembly GO:0022607 360 0.202
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.194
response to decreased oxygen levels GO:0036293 237 0.190
organic hydroxy compound metabolic process GO:1901615 115 0.183
Mouse
cell cell signaling GO:0007267 335 0.180
cellular component biogenesis GO:0044085 368 0.168
Mouse
lipid metabolic process GO:0006629 283 0.167
oxoacid metabolic process GO:0043436 290 0.165
response to hypoxia GO:0001666 231 0.164
metal ion transport GO:0030001 289 0.148
nitrogen compound transport GO:0071705 229 0.142
response to wounding GO:0009611 254 0.136
Mouse
response to inorganic substance GO:0010035 377 0.126
Human
response to oxidative stress GO:0006979 186 0.119
protein heterooligomerization GO:0051291 89 0.119
programmed cell death GO:0012501 392 0.118
Rat
cellular lipid metabolic process GO:0044255 208 0.117
response to external biotic stimulus GO:0043207 221 0.116
regulation of phosphate metabolic process GO:0019220 349 0.111
Human
regulation of cellular localization GO:0060341 263 0.104
sensory perception of pain GO:0019233 73 0.104
Rat
neurological system process GO:0050877 219 0.103
Rat
regulation of molecular function GO:0065009 398 0.102
Rat
response to metal ion GO:0010038 253 0.099
Human
synaptic transmission GO:0007268 235 0.098
positive regulation of transport GO:0051050 245 0.095
reproductive process GO:0022414 372 0.094
small molecule biosynthetic process GO:0044283 124 0.089
cell motility GO:0048870 202 0.086
Rat
carboxylic acid metabolic process GO:0019752 289 0.086
homeostatic process GO:0042592 331 0.084
Rat
regulation of ion transport GO:0043269 245 0.084
regulation of programmed cell death GO:0043067 341 0.084
Rat
cellular amino acid metabolic process GO:0006520 107 0.080
blood circulation GO:0008015 183 0.079
Rat
macromolecular complex assembly GO:0065003 273 0.077
Mouse
response to oxygen levels GO:0070482 265 0.076
Rat
regulation of cellular component organization GO:0051128 368 0.075
Mouse
cellular chemical homeostasis GO:0055082 247 0.075
protein oligomerization GO:0051259 191 0.075
regulation of blood vessel size GO:0050880 89 0.073
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.073
cellular response to oxygen containing compound GO:1901701 386 0.068
positive regulation of phosphorus metabolic process GO:0010562 262 0.067
Human
single organism cellular localization GO:1902580 102 0.065
apoptotic process GO:0006915 381 0.065
Rat
response to camp GO:0051591 91 0.064
purine nucleotide catabolic process GO:0006195 136 0.061
female gonad development GO:0008585 53 0.061
regulation of multicellular organismal development GO:2000026 376 0.061
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.060
Human
positive regulation of response to stimulus GO:0048584 285 0.058
Human
response to organophosphorus GO:0046683 102 0.058
regulation of cellular protein metabolic process GO:0032268 267 0.058
Rat
sensory perception GO:0007600 101 0.057
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.057
response to nutrient levels GO:0031667 370 0.056
Rat
regulation of peptide transport GO:0090087 87 0.055
regulation of protein metabolic process GO:0051246 289 0.053
Rat
amine metabolic process GO:0009308 38 0.053
secretion GO:0046903 307 0.052
positive regulation of hydrolase activity GO:0051345 86 0.052
Rat
developmental process involved in reproduction GO:0003006 159 0.052
regulation of synaptic transmission GO:0050804 141 0.052
lipid biosynthetic process GO:0008610 128 0.051
organonitrogen compound catabolic process GO:1901565 179 0.051
cellular component movement GO:0006928 248 0.051
Rat
metal ion homeostasis GO:0055065 186 0.051
ion homeostasis GO:0050801 212 0.051
Rat
protein processing GO:0016485 68 0.051
proteolysis GO:0006508 175 0.050
Rat
chemical homeostasis GO:0048878 292 0.050
Rat
organic acid metabolic process GO:0006082 292 0.049
ion transmembrane transport GO:0034220 365 0.048
positive regulation of secretion GO:0051047 140 0.046
regulation of metal ion transport GO:0010959 118 0.046
cation transport GO:0006812 382 0.046
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
organophosphate catabolic process GO:0046434 148 0.045
regulation of intracellular signal transduction GO:1902531 218 0.045
Human
purine ribonucleotide metabolic process GO:0009150 227 0.045
positive regulation of programmed cell death GO:0043068 157 0.045
Rat
positive regulation of cell communication GO:0010647 271 0.044
Human
response to corticosteroid GO:0031960 235 0.044
organic anion transport GO:0015711 132 0.044
cellular response to endogenous stimulus GO:0071495 377 0.043
neuron differentiation GO:0030182 368 0.043
regulation of blood pressure GO:0008217 83 0.042
cellular amine metabolic process GO:0044106 38 0.042
rhythmic process GO:0048511 156 0.042
heterocycle catabolic process GO:0046700 167 0.041
intracellular signal transduction GO:0035556 314 0.040
Human
positive regulation of phosphorylation GO:0042327 177 0.040
Human
second messenger mediated signaling GO:0019932 51 0.039
response to extracellular stimulus GO:0009991 380 0.039
Rat
macromolecular complex subunit organization GO:0043933 339 0.039
Mouse
peptide metabolic process GO:0006518 32 0.039
nucleoside metabolic process GO:0009116 179 0.038
cytoskeleton organization GO:0007010 111 0.038
Mouse
single organism reproductive process GO:0044702 297 0.038
regulation of signal transduction GO:0009966 318 0.037
Human Mouse
purine nucleoside metabolic process GO:0042278 169 0.037
regulation of immune system process GO:0002682 123 0.036
Mouse
signal release GO:0023061 145 0.036
regulation of secretion by cell GO:1903530 208 0.036
ribonucleotide catabolic process GO:0009261 136 0.035
cellular nitrogen compound catabolic process GO:0044270 163 0.035
organic acid transport GO:0015849 116 0.035
organelle organization GO:0006996 266 0.035
Mouse
development of primary sexual characteristics GO:0045137 107 0.035
nucleoside phosphate catabolic process GO:1901292 140 0.035
regulation of cell proliferation GO:0042127 359 0.035
Rat
response to glucocorticoid GO:0051384 223 0.035
positive regulation of catalytic activity GO:0043085 184 0.034
Rat
secretion by cell GO:0032940 248 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.034
response to monosaccharide GO:0034284 159 0.033
response to biotic stimulus GO:0009607 226 0.033
protein complex assembly GO:0006461 263 0.033
Mouse
organic hydroxy compound biosynthetic process GO:1901617 51 0.033
Mouse
regulation of response to stress GO:0080134 126 0.033
response to reactive oxygen species GO:0000302 120 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
Rat
neuron development GO:0048666 286 0.033
positive regulation of signaling GO:0023056 270 0.032
Human
negative regulation of multicellular organismal process GO:0051241 203 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
protein complex biogenesis GO:0070271 263 0.032
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
nucleotide catabolic process GO:0009166 139 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
cellular ketone metabolic process GO:0042180 51 0.031
purine nucleoside triphosphate catabolic process GO:0009146 122 0.031
anion transmembrane transport GO:0098656 77 0.031
cellular response to oxidative stress GO:0034599 76 0.031
positive regulation of cellular protein metabolic process GO:0032270 167 0.031
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.030
Human
regulation of anatomical structure size GO:0090066 135 0.030
Mouse Rat
inorganic ion transmembrane transport GO:0098660 229 0.030
aging GO:0007568 241 0.030
Rat
immune system process GO:0002376 204 0.030
Mouse
gonad development GO:0008406 104 0.030
response to acid chemical GO:0001101 222 0.030
tissue development GO:0009888 252 0.029
Mouse Rat
vitamin d metabolic process GO:0042359 4 0.029
nucleotide metabolic process GO:0009117 279 0.029
ribonucleoside triphosphate catabolic process GO:0009203 122 0.029
cellular macromolecule localization GO:0070727 122 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
intracellular transport GO:0046907 185 0.029
organophosphate metabolic process GO:0019637 370 0.029
Mouse
neuronal action potential GO:0019228 35 0.028
ribonucleoside metabolic process GO:0009119 174 0.028
carboxylic acid transport GO:0046942 115 0.028
response to estrogen GO:0043627 232 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
aromatic compound catabolic process GO:0019439 168 0.028
response to carbohydrate GO:0009743 183 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
Rat
ribose phosphate metabolic process GO:0019693 235 0.027
negative regulation of cellular component organization GO:0051129 83 0.027
nucleoside catabolic process GO:0009164 126 0.027
nucleoside triphosphate metabolic process GO:0009141 144 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
Rat
multicellular organism reproduction GO:0032504 233 0.027
cellular ion homeostasis GO:0006873 184 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
leukocyte cell cell adhesion GO:0007159 4 0.027
negative regulation of cell death GO:0060548 229 0.027
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.027
ribonucleoside catabolic process GO:0042454 126 0.027
regulation of response to external stimulus GO:0032101 106 0.026
reproduction GO:0000003 245 0.026
multi organism reproductive process GO:0044703 262 0.026
response to hexose GO:0009746 144 0.026
single organism catabolic process GO:0044712 283 0.026
female sex differentiation GO:0046660 59 0.026
regulation of apoptotic process GO:0042981 335 0.026
Rat
cell projection organization GO:0030030 302 0.025
positive regulation of secretion by cell GO:1903532 128 0.025
granulocyte chemotaxis GO:0071621 15 0.025
hormone transport GO:0009914 121 0.025
potassium ion transport GO:0006813 97 0.025
sex differentiation GO:0007548 113 0.025
regulation of catalytic activity GO:0050790 304 0.025
Rat
negative regulation of innate immune response GO:0045824 4 0.025
purine containing compound metabolic process GO:0072521 253 0.025
purine containing compound catabolic process GO:0072523 138 0.025
regulation of hormone secretion GO:0046883 106 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
amide transport GO:0042886 105 0.025
cellular response to nitrogen compound GO:1901699 210 0.024
cellular amide metabolic process GO:0043603 44 0.024
reproductive system development GO:0061458 128 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
Rat
calcium ion homeostasis GO:0055074 162 0.024
response to calcium ion GO:0051592 59 0.024
Human
negative regulation of metabolic process GO:0009892 331 0.024
purine ribonucleotide catabolic process GO:0009154 136 0.024
negative regulation of transport GO:0051051 136 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.023
rna biosynthetic process GO:0032774 380 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.023
cation homeostasis GO:0055080 195 0.023
positive regulation of ion transport GO:0043270 94 0.023
intracellular protein transport GO:0006886 79 0.023
monocarboxylic acid metabolic process GO:0032787 152 0.023
protein complex subunit organization GO:0071822 302 0.023
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.023
response to nutrient GO:0007584 248 0.023
Rat
anatomical structure morphogenesis GO:0009653 298 0.023
wound healing GO:0042060 122 0.023
Mouse
head development GO:0060322 247 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
response to bacterium GO:0009617 200 0.023
transmembrane transport GO:0055085 412 0.023
purine ribonucleoside catabolic process GO:0046130 124 0.023
cell migration GO:0016477 197 0.022
Rat
positive regulation of molecular function GO:0044093 230 0.022
Rat
cellular homeostasis GO:0019725 252 0.022
leukocyte migration GO:0050900 38 0.022
response to ketone GO:1901654 182 0.022
regulation of hormone levels GO:0010817 187 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
adult locomotory behavior GO:0008344 4 0.021
smooth muscle cell proliferation GO:0048659 77 0.021
Rat
guanosine containing compound metabolic process GO:1901068 74 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
sexual reproduction GO:0019953 148 0.021
positive regulation of cell death GO:0010942 184 0.021
Rat
regulation of cellular catabolic process GO:0031329 101 0.020
regulation of locomotion GO:0040012 148 0.020
Rat
phospholipid metabolic process GO:0006644 61 0.020
Mouse
response to radiation GO:0009314 137 0.020
macromolecule localization GO:0033036 252 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
action potential GO:0001508 54 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
Human
regulation of phosphorylation GO:0042325 248 0.020
Human
regulation of nucleotide metabolic process GO:0006140 117 0.020
reproductive structure development GO:0048608 128 0.020
regulation of hydrolase activity GO:0051336 143 0.019
Rat
multicellular organismal reproductive process GO:0048609 233 0.019
regulation of protein modification process GO:0031399 194 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
positive regulation of developmental process GO:0051094 283 0.019
Rat
protein phosphorylation GO:0006468 345 0.019
regulation of tube size GO:0035150 89 0.019
Rat
localization of cell GO:0051674 202 0.019
Rat
glycosyl compound metabolic process GO:1901657 182 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
Mouse
neuropeptide signaling pathway GO:0007218 29 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.018
cellular cation homeostasis GO:0030003 180 0.018
central nervous system development GO:0007417 311 0.018
gtp metabolic process GO:0046039 72 0.018
membrane organization GO:0061024 94 0.018
Mouse
single organism organelle organization GO:1902589 180 0.018
Mouse
divalent metal ion transport GO:0070838 132 0.018
anterior posterior pattern specification GO:0009952 1 0.018
cardiovascular system development GO:0072358 134 0.018
development of primary female sexual characteristics GO:0046545 56 0.018
mapk cascade GO:0000165 140 0.018
Human
response to temperature stimulus GO:0009266 94 0.018
regulation of gtpase activity GO:0043087 57 0.017
response to activity GO:0014823 73 0.017
organic substance catabolic process GO:1901575 316 0.017
immune response GO:0006955 104 0.017
Mouse
positive regulation of gene expression GO:0010628 244 0.017
Rat
cellular protein localization GO:0034613 122 0.017
regulation of cell projection size GO:0032536 1 0.017
multi multicellular organism process GO:0044706 138 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
calcium ion transport GO:0006816 131 0.017
forebrain development GO:0030900 98 0.017
catabolic process GO:0009056 351 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
response to lead ion GO:0010288 33 0.017
protein maturation GO:0051604 68 0.017
neuron projection development GO:0031175 273 0.017
hydrogen peroxide metabolic process GO:0042743 13 0.017
lipid localization GO:0010876 62 0.017
regulation of rna metabolic process GO:0051252 391 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
regulation of sensory perception of pain GO:0051930 29 0.017
transcription dna templated GO:0006351 377 0.017
response to retinoic acid GO:0032526 63 0.017
circulatory system process GO:0003013 183 0.017
Rat
monocarboxylic acid biosynthetic process GO:0072330 48 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
alcohol biosynthetic process GO:0046165 38 0.016
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.016
response to vitamin GO:0033273 131 0.016
eye morphogenesis GO:0048592 4 0.016
brain development GO:0007420 247 0.016
negative regulation of response to external stimulus GO:0032102 37 0.016
regulation of homeostatic process GO:0032844 101 0.016
Rat
ossification GO:0001503 70 0.016
Mouse
muscle system process GO:0003012 115 0.016
gtp catabolic process GO:0006184 71 0.016
single organism biosynthetic process GO:0044711 342 0.016
positive regulation of nucleotide catabolic process GO:0030813 53 0.016
membrane depolarization GO:0051899 32 0.016
Rat
regulation of organic acid transport GO:0032890 35 0.016
peptide transport GO:0015833 97 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
positive regulation of gtpase activity GO:0043547 47 0.016
hormone secretion GO:0046879 115 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
positive regulation of synaptic transmission GO:0050806 62 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
circadian rhythm GO:0007623 88 0.015
regeneration GO:0031099 163 0.015
ras protein signal transduction GO:0007265 29 0.015
glycerophospholipid metabolic process GO:0006650 47 0.015
Mouse
single organism intracellular transport GO:1902582 166 0.015
multicellular organismal signaling GO:0035637 44 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
axis specification GO:0009798 4 0.015
response to ethanol GO:0045471 162 0.015
cognition GO:0050890 92 0.015
regulation of peptide secretion GO:0002791 82 0.015
gland development GO:0048732 155 0.015
actin filament based process GO:0030029 86 0.014
Mouse
organophosphate biosynthetic process GO:0090407 143 0.014
Mouse
response to amino acid GO:0043200 75 0.014
protein localization GO:0008104 191 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
transmission of nerve impulse GO:0019226 42 0.014
rho protein signal transduction GO:0007266 11 0.014
sulfur compound metabolic process GO:0006790 70 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
Human
response to toxic substance GO:0009636 133 0.014
blood coagulation GO:0007596 26 0.014
single organism behavior GO:0044708 130 0.014
response to lipopolysaccharide GO:0032496 191 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of neurological system process GO:0031644 43 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
Rat
locomotion GO:0040011 237 0.014
Rat
response to other organism GO:0051707 220 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of necroptotic process GO:0060544 2 0.014
monocarboxylic acid transport GO:0015718 52 0.014
response to estradiol GO:0032355 164 0.014
response to purine containing compound GO:0014074 126 0.014
response to fibroblast growth factor GO:0071774 29 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
coagulation GO:0050817 28 0.013
regulation of sensory perception GO:0051931 29 0.013
innate immune response GO:0045087 35 0.013
positive regulation of cell migration GO:0030335 96 0.013
Rat
regulation of nervous system development GO:0051960 264 0.013
cytoplasmic transport GO:0016482 115 0.013
cell adhesion GO:0007155 110 0.013
cellular response to external stimulus GO:0071496 118 0.013
regulation of neurogenesis GO:0050767 247 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
positive regulation of nervous system development GO:0051962 178 0.013
vascular process in circulatory system GO:0003018 96 0.013
Rat
ovulation cycle process GO:0022602 50 0.013
feeding behavior GO:0007631 53 0.013
response to growth factor GO:0070848 189 0.013
myeloid leukocyte differentiation GO:0002573 20 0.013
positive regulation of signal transduction GO:0009967 175 0.013
Human
cation transmembrane transport GO:0098655 263 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
regulation of catabolic process GO:0009894 113 0.013
gamete generation GO:0007276 124 0.013
erythrocyte differentiation GO:0030218 1 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
axon development GO:0061564 96 0.012
regulation of mapk cascade GO:0043408 116 0.012
Human
negative regulation of molecular function GO:0044092 133 0.012
regulation of system process GO:0044057 208 0.012
Rat
cellular response to organic cyclic compound GO:0071407 202 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
regulation of calcium ion transport GO:0051924 77 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
single organism membrane organization GO:0044802 74 0.012
positive regulation of necrotic cell death GO:0010940 4 0.012
regulation of membrane potential GO:0042391 110 0.012
Rat
cellular modified amino acid metabolic process GO:0006575 61 0.012
glycerolipid metabolic process GO:0046486 67 0.012
Mouse
cellular hormone metabolic process GO:0034754 49 0.012
response to glucose GO:0009749 136 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
cytokine production GO:0001816 61 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
acid secretion GO:0046717 48 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
growth GO:0040007 165 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
granulocyte migration GO:0097530 16 0.012
regulation of transcription dna templated GO:0006355 374 0.012
circulatory system development GO:0072359 134 0.012
muscle cell proliferation GO:0033002 84 0.012
Rat
negative regulation of programmed cell death GO:0043069 183 0.012
Rat
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 13 0.012
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
regulation of cell cycle GO:0051726 73 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of body fluid levels GO:0050878 90 0.012
necroptotic process GO:0070266 2 0.012
response to food GO:0032094 27 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
blood vessel morphogenesis GO:0048514 58 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
regulation of response to wounding GO:1903034 69 0.011
embryonic axis specification GO:0000578 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
cell type specific apoptotic process GO:0097285 134 0.011
oxygen transport GO:0015671 2 0.011
rna localization GO:0006403 4 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
learning or memory GO:0007611 90 0.011
nucleic acid templated transcription GO:0097659 379 0.011
regulation of peptidase activity GO:0052547 55 0.011
Rat
negative regulation of ion transport GO:0043271 51 0.011
regulation of cellular extravasation GO:0002691 2 0.011
cell fate determination GO:0001709 2 0.011
regulation of extracellular matrix constituent secretion GO:0003330 2 0.011
coenzyme metabolic process GO:0006732 86 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
negative regulation of vesicle fusion GO:0031339 2 0.011
digestive system development GO:0055123 41 0.011
peptidyl amino acid modification GO:0018193 126 0.011
heterotypic cell cell adhesion GO:0034113 2 0.011
protein targeting GO:0006605 61 0.011
cellular catabolic process GO:0044248 295 0.011
cellular response to camp GO:0071320 26 0.011
response to fatty acid GO:0070542 65 0.011
fatty acid metabolic process GO:0006631 99 0.011
glucose homeostasis GO:0042593 75 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.011
response to alkaloid GO:0043279 132 0.011
inflammatory response GO:0006954 150 0.011
Rat
regulation of cell projection organization GO:0031344 175 0.011
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
regulation of protein processing GO:0070613 50 0.011
cell activation GO:0001775 97 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
positive regulation of gtp catabolic process GO:0033126 48 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.010
regulation of neuron projection development GO:0010975 161 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
dephosphorylation GO:0016311 98 0.010
hindlimb morphogenesis GO:0035137 2 0.010
negative regulation of cell communication GO:0010648 158 0.010
regulation of transmembrane transport GO:0034762 122 0.010
divalent inorganic cation transport GO:0072511 134 0.010
peptide hormone secretion GO:0030072 84 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
response to insulin GO:0032868 133 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010

Alox15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.046
eye and adnexa disease DOID:1492 0 0.035
sensory system disease DOID:0050155 0 0.035
eye disease DOID:5614 0 0.031
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
cardiovascular system disease DOID:1287 0 0.016
endocrine system disease DOID:28 0 0.013
retinitis pigmentosa DOID:10584 0 0.012
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
central nervous system disease DOID:331 0 0.010