Rattus norvegicus

62 known processes

Alox5

arachidonate 5-lipoxygenase

(Aliases: LOX5A)

Alox5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.218
regulation of signal transduction GO:0009966 318 0.203
circulatory system process GO:0003013 183 0.173
response to corticosteroid GO:0031960 235 0.151
positive regulation of response to stimulus GO:0048584 285 0.148
anatomical structure morphogenesis GO:0009653 298 0.145
regulation of molecular function GO:0065009 398 0.141
Rat
regulation of cell proliferation GO:0042127 359 0.141
Rat
regulation of immune system process GO:0002682 123 0.132
inflammatory response GO:0006954 150 0.131
positive regulation of multicellular organismal process GO:0051240 387 0.130
regulation of catalytic activity GO:0050790 304 0.118
Rat
positive regulation of developmental process GO:0051094 283 0.111
Rat
cell migration GO:0016477 197 0.111
Rat
regulation of phosphorylation GO:0042325 248 0.108
response to inorganic substance GO:0010035 377 0.106
positive regulation of cell development GO:0010720 176 0.106
divalent inorganic cation homeostasis GO:0072507 165 0.104
regulation of cell activation GO:0050865 50 0.101
intracellular signal transduction GO:0035556 314 0.100
cell motility GO:0048870 202 0.096
Rat
positive regulation of immune system process GO:0002684 90 0.095
single organism biosynthetic process GO:0044711 342 0.093
Human Mouse Rat
response to estrogen GO:0043627 232 0.089
defense response GO:0006952 194 0.088
catabolic process GO:0009056 351 0.088
neurological system process GO:0050877 219 0.085
regulation of programmed cell death GO:0043067 341 0.084
Rat
cellular lipid metabolic process GO:0044255 208 0.081
regulation of protein metabolic process GO:0051246 289 0.080
Rat
neuron development GO:0048666 286 0.080
regulation of phosphorus metabolic process GO:0051174 349 0.079
tissue development GO:0009888 252 0.077
Rat
regulation of leukocyte activation GO:0002694 45 0.075
cellular response to oxygen containing compound GO:1901701 386 0.074
cellular homeostasis GO:0019725 252 0.074
divalent metal ion transport GO:0070838 132 0.073
cation transport GO:0006812 382 0.072
response to cytokine GO:0034097 215 0.071
apoptotic process GO:0006915 381 0.070
Rat
localization of cell GO:0051674 202 0.070
Rat
regulation of muscle system process GO:0090257 79 0.069
ribonucleotide metabolic process GO:0009259 231 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.068
regulation of rna metabolic process GO:0051252 391 0.067
reproductive process GO:0022414 372 0.066
secretion GO:0046903 307 0.063
regulation of phosphate metabolic process GO:0019220 349 0.062
chemotaxis GO:0006935 66 0.062
monocarboxylic acid metabolic process GO:0032787 152 0.062
blood circulation GO:0008015 183 0.061
regulation of cellular component organization GO:0051128 368 0.060
biological adhesion GO:0022610 110 0.060
Rat
head development GO:0060322 247 0.060
cellular response to stress GO:0033554 269 0.059
organophosphate metabolic process GO:0019637 370 0.059
organelle organization GO:0006996 266 0.058
regulation of intracellular signal transduction GO:1902531 218 0.057
muscle system process GO:0003012 115 0.057
cellular chemical homeostasis GO:0055082 247 0.057
response to glucocorticoid GO:0051384 223 0.057
neuron projection development GO:0031175 273 0.057
carboxylic acid metabolic process GO:0019752 289 0.056
nitrogen compound transport GO:0071705 229 0.056
positive regulation of phosphorylation GO:0042327 177 0.053
cellular component biogenesis GO:0044085 368 0.053
hemopoiesis GO:0030097 34 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.051
regulation of neuron differentiation GO:0045664 208 0.051
cellular catabolic process GO:0044248 295 0.051
macromolecular complex subunit organization GO:0043933 339 0.051
regulation of cellular protein metabolic process GO:0032268 267 0.050
Rat
locomotion GO:0040011 237 0.050
Rat
b cell differentiation GO:0030183 2 0.049
response to acid chemical GO:0001101 222 0.049
immune response GO:0006955 104 0.049
transcription dna templated GO:0006351 377 0.049
response to ketone GO:1901654 182 0.049
cell activation GO:0001775 97 0.048
oxoacid metabolic process GO:0043436 290 0.048
protein phosphorylation GO:0006468 345 0.048
urogenital system development GO:0001655 78 0.048
heart process GO:0003015 57 0.048
glycerolipid metabolic process GO:0046486 67 0.047
lipid biosynthetic process GO:0008610 128 0.047
Human Mouse Rat
regulation of neurogenesis GO:0050767 247 0.047
blood vessel development GO:0001568 69 0.047
regulation of anatomical structure morphogenesis GO:0022603 141 0.046
organ regeneration GO:0031100 101 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
Rat
regulation of protein kinase activity GO:0045859 105 0.046
regulation of defense response GO:0031347 68 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
carbohydrate derivative catabolic process GO:1901136 147 0.045
response to decreased oxygen levels GO:0036293 237 0.045
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.045
regulation of blood pressure GO:0008217 83 0.045
oxidation reduction process GO:0055114 304 0.044
lipid metabolic process GO:0006629 283 0.044
taxis GO:0042330 67 0.043
regulation of kinase activity GO:0043549 117 0.043
gland development GO:0048732 155 0.043
response to peptide hormone GO:0043434 278 0.043
fatty acid metabolic process GO:0006631 99 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.043
cellular ion homeostasis GO:0006873 184 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.042
cell projection organization GO:0030030 302 0.042
cellular component movement GO:0006928 248 0.042
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.042
regulation of secretion GO:0051046 224 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
Rat
phospholipid metabolic process GO:0006644 61 0.041
positive regulation of immune response GO:0050778 42 0.041
organic acid metabolic process GO:0006082 292 0.040
regulation of rna biosynthetic process GO:2001141 381 0.040
central nervous system development GO:0007417 311 0.040
positive regulation of leukocyte activation GO:0002696 30 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
brain development GO:0007420 247 0.040
single organism catabolic process GO:0044712 283 0.040
response to biotic stimulus GO:0009607 226 0.040
nucleoside phosphate catabolic process GO:1901292 140 0.039
immune system development GO:0002520 41 0.039
single organism reproductive process GO:0044702 297 0.039
rna biosynthetic process GO:0032774 380 0.039
cell adhesion GO:0007155 110 0.038
Rat
positive regulation of transcription dna templated GO:0045893 197 0.038
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.038
regulation of hydrolase activity GO:0051336 143 0.038
Rat
negative regulation of signaling GO:0023057 157 0.038
protein complex subunit organization GO:0071822 302 0.038
monovalent inorganic cation transport GO:0015672 172 0.038
negative regulation of metabolic process GO:0009892 331 0.038
mapk cascade GO:0000165 140 0.037
positive regulation of molecular function GO:0044093 230 0.037
Rat
regulation of system process GO:0044057 208 0.037
heart contraction GO:0060047 57 0.037
development of primary sexual characteristics GO:0045137 107 0.037
positive regulation of intracellular signal transduction GO:1902533 138 0.037
response to mineralocorticoid GO:0051385 49 0.036
regulation of cell differentiation GO:0045595 320 0.036
Rat
response to amino acid GO:0043200 75 0.036
cellular amine metabolic process GO:0044106 38 0.036
small molecule biosynthetic process GO:0044283 124 0.035
Human Mouse Rat
positive regulation of signaling GO:0023056 270 0.035
developmental growth GO:0048589 100 0.035
regulation of response to external stimulus GO:0032101 106 0.035
positive regulation of long term synaptic potentiation GO:1900273 4 0.035
response to bacterium GO:0009617 200 0.035
protein complex assembly GO:0006461 263 0.035
protein oligomerization GO:0051259 191 0.034
macromolecule localization GO:0033036 252 0.034
neuron differentiation GO:0030182 368 0.034
programmed cell death GO:0012501 392 0.034
Rat
negative regulation of response to stimulus GO:0048585 155 0.034
positive regulation of lymphocyte activation GO:0051251 25 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.033
transmembrane transport GO:0055085 412 0.033
organic substance catabolic process GO:1901575 316 0.033
cell growth GO:0016049 104 0.033
respiratory gaseous exchange GO:0007585 4 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
regulation of cell development GO:0060284 263 0.033
calcium ion homeostasis GO:0055074 162 0.033
vitamin d metabolic process GO:0042359 4 0.033
multicellular organism reproduction GO:0032504 233 0.033
negative regulation of developmental process GO:0051093 125 0.032
regulation of transferase activity GO:0051338 123 0.032
aromatic compound catabolic process GO:0019439 168 0.032
signal transduction by phosphorylation GO:0023014 144 0.031
multi organism reproductive process GO:0044703 262 0.031
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
regulation of behavior GO:0050795 61 0.031
response to growth factor GO:0070848 189 0.031
response to toxic substance GO:0009636 133 0.031
salivary gland development GO:0007431 3 0.031
regulation of response to wounding GO:1903034 69 0.031
metal ion homeostasis GO:0055065 186 0.031
negative regulation of cell differentiation GO:0045596 99 0.030
regulation of map kinase activity GO:0043405 53 0.030
saliva secretion GO:0046541 3 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
regulation of ion transport GO:0043269 245 0.030
rna metabolic process GO:0016070 406 0.030
muscle contraction GO:0006936 88 0.029
response to testosterone GO:0033574 55 0.029
actin mediated cell contraction GO:0070252 12 0.029
response to external biotic stimulus GO:0043207 221 0.029
regulation of blood circulation GO:1903522 110 0.029
reproductive structure development GO:0048608 128 0.029
leukocyte activation GO:0045321 76 0.029
neuron apoptotic process GO:0051402 88 0.029
regulation of secretion by cell GO:1903530 208 0.029
response to oxygen levels GO:0070482 265 0.029
actin filament based process GO:0030029 86 0.029
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.029
renal system process GO:0003014 40 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
cellular component assembly GO:0022607 360 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
positive regulation of signal transduction GO:0009967 175 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
response to reactive oxygen species GO:0000302 120 0.028
positive regulation of cell activation GO:0050867 34 0.028
negative regulation of phosphorus metabolic process GO:0010563 80 0.028
proteolysis GO:0006508 175 0.028
Rat
cation homeostasis GO:0055080 195 0.028
regulation of anatomical structure size GO:0090066 135 0.028
hematopoietic or lymphoid organ development GO:0048534 36 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.027
stress activated mapk cascade GO:0051403 35 0.027
ras protein signal transduction GO:0007265 29 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.027
unsaturated fatty acid metabolic process GO:0033559 39 0.027
regulation of protein serine threonine kinase activity GO:0071900 64 0.027
cell type specific apoptotic process GO:0097285 134 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
positive regulation of cellular component movement GO:0051272 102 0.027
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
positive regulation of apoptotic process GO:0043065 154 0.027
Rat
positive regulation of transport GO:0051050 245 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.026
negative regulation of signal transduction GO:0009968 83 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
interleukin 6 production GO:0032635 12 0.026
sexual reproduction GO:0019953 148 0.026
regulation of striated muscle contraction GO:0006942 21 0.026
response to estradiol GO:0032355 164 0.026
amine metabolic process GO:0009308 38 0.026
cytokine production GO:0001816 61 0.026
metal ion transport GO:0030001 289 0.026
behavior GO:0007610 205 0.026
inorganic cation transmembrane transport GO:0098662 202 0.026
positive regulation of protein modification process GO:0031401 142 0.025
nucleic acid templated transcription GO:0097659 379 0.025
cardiac muscle cell contraction GO:0086003 10 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
regulation of response to stress GO:0080134 126 0.025
protein complex biogenesis GO:0070271 263 0.025
nucleoside metabolic process GO:0009116 179 0.025
macromolecular complex assembly GO:0065003 273 0.025
t helper 1 type immune response GO:0042088 1 0.025
membrane hyperpolarization GO:0060081 11 0.025
growth GO:0040007 165 0.025
angiogenesis GO:0001525 53 0.025
gastrulation GO:0007369 2 0.024
regulation of mapk cascade GO:0043408 116 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
calcium ion transport GO:0006816 131 0.024
positive regulation of gene expression GO:0010628 244 0.024
Rat
neuron projection morphogenesis GO:0048812 122 0.024
cytoskeleton organization GO:0007010 111 0.024
regulation of interleukin 6 production GO:0032675 12 0.024
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
response to metal ion GO:0010038 253 0.024
regulation of developmental growth GO:0048638 45 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
response to nutrient levels GO:0031667 370 0.024
sodium ion transport GO:0006814 82 0.024
positive regulation of rna metabolic process GO:0051254 203 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
ion transmembrane transport GO:0034220 365 0.023
regulation of erk1 and erk2 cascade GO:0070372 41 0.023
positive regulation of cytokine production GO:0001819 42 0.023
immunoglobulin mediated immune response GO:0016064 4 0.023
kidney development GO:0001822 67 0.023
negative regulation of neurogenesis GO:0050768 78 0.023
regulation of protein modification process GO:0031399 194 0.023
n methyl d aspartate receptor clustering GO:0097114 2 0.023
sensory perception of pain GO:0019233 73 0.023
dna metabolic process GO:0006259 96 0.022
positive regulation of mapk cascade GO:0043410 92 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
cell part morphogenesis GO:0032990 123 0.022
purine containing compound metabolic process GO:0072521 253 0.022
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.022
gonad development GO:0008406 104 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.022
circulatory system development GO:0072359 134 0.022
epithelium development GO:0060429 96 0.022
Rat
regulation of transcription dna templated GO:0006355 374 0.022
erk1 and erk2 cascade GO:0070371 48 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
secretion by cell GO:0032940 248 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
organ morphogenesis GO:0009887 75 0.022
regeneration GO:0031099 163 0.022
salivary gland morphogenesis GO:0007435 1 0.022
response to hexose GO:0009746 144 0.022
organophosphate catabolic process GO:0046434 148 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
cation transmembrane transport GO:0098655 263 0.021
positive regulation of nervous system development GO:0051962 178 0.021
divalent inorganic cation transport GO:0072511 134 0.021
regulation of inflammatory response GO:0050727 48 0.021
positive regulation of immunoglobulin production GO:0002639 4 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
Rat
regulation of immunoglobulin production GO:0002637 4 0.021
regulation of leukocyte differentiation GO:1902105 20 0.021
response to oxidative stress GO:0006979 186 0.021
sex differentiation GO:0007548 113 0.021
regulation of transporter activity GO:0032409 50 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.020
response to extracellular stimulus GO:0009991 380 0.020
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.020
regulation of growth GO:0040008 105 0.020
neurotransmitter gated ion channel clustering GO:0072578 3 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
regulation of cellular localization GO:0060341 263 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
positive regulation of behavior GO:0048520 38 0.019
ossification GO:0001503 70 0.019
intracellular transport GO:0046907 185 0.019
response to insulin GO:0032868 133 0.019
nucleotide metabolic process GO:0009117 279 0.019
telencephalon development GO:0021537 62 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
positive regulation of transferase activity GO:0051347 81 0.019
negative regulation of nervous system development GO:0051961 79 0.019
striated muscle contraction GO:0006941 44 0.019
heterocycle catabolic process GO:0046700 167 0.019
negative regulation of molecular function GO:0044092 133 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of lymphocyte activation GO:0051249 34 0.019
regulation of homeostatic process GO:0032844 101 0.019
Rat
regulation of muscle contraction GO:0006937 53 0.019
regulation of cell projection organization GO:0031344 175 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
negative regulation of cell development GO:0010721 82 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
cytoplasmic transport GO:0016482 115 0.019
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.019
regulation of transmembrane transporter activity GO:0022898 49 0.019
response to carbohydrate GO:0009743 183 0.019
response to monosaccharide GO:0034284 159 0.018
response to hypoxia GO:0001666 231 0.018
response to radiation GO:0009314 137 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
Rat
positive regulation of chemotaxis GO:0050921 23 0.018
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.018
renal system development GO:0072001 67 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
camp metabolic process GO:0046058 63 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
positive regulation of locomotion GO:0040017 102 0.018
Rat
regulation of nervous system development GO:0051960 264 0.018
negative regulation of immune system process GO:0002683 39 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
potassium ion transmembrane transport GO:0071805 71 0.018
organic acid biosynthetic process GO:0016053 83 0.018
Human Mouse Rat
ion homeostasis GO:0050801 212 0.018
Rat
regulation of nucleotide metabolic process GO:0006140 117 0.018
positive regulation of kinase activity GO:0033674 77 0.018
cellular response to hexose stimulus GO:0071331 65 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
regulation of cytokine production GO:0001817 56 0.017
tube development GO:0035295 89 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
regulation of mononuclear cell proliferation GO:0032944 26 0.017
mononuclear cell proliferation GO:0032943 29 0.017
negative regulation of response to wounding GO:1903035 23 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
potassium ion transport GO:0006813 97 0.017
regulation of chemotaxis GO:0050920 29 0.017
response to peptide GO:1901652 292 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
involuntary skeletal muscle contraction GO:0003011 2 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
regulation of organ formation GO:0003156 2 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
multi multicellular organism process GO:0044706 138 0.017
positive regulation of blood circulation GO:1903524 65 0.017
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
response to calcium ion GO:0051592 59 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
regulation of metal ion transport GO:0010959 118 0.016
nucleotide catabolic process GO:0009166 139 0.016
protein transport GO:0015031 132 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
formation of primary germ layer GO:0001704 1 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
learning or memory GO:0007611 90 0.016
cellular response to acid chemical GO:0071229 75 0.016
single organism organelle organization GO:1902589 180 0.016
cellular response to hypoxia GO:0071456 51 0.016
gamete generation GO:0007276 124 0.016
regulation of neuron projection development GO:0010975 161 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
positive regulation of cell migration GO:0030335 96 0.016
Rat
respiratory system process GO:0003016 3 0.016
regulation of heart contraction GO:0008016 48 0.016
cellular ketone metabolic process GO:0042180 51 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
single organism cellular localization GO:1902580 102 0.016
hepaticobiliary system development GO:0061008 90 0.016
regulation of calcium ion transport GO:0051924 77 0.016
regulation of platelet activation GO:0010543 2 0.016
nucleoside catabolic process GO:0009164 126 0.016
vitamin biosynthetic process GO:0009110 3 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
Rat
regulation of odontogenesis of dentin containing tooth GO:0042487 2 0.016
cellular cation homeostasis GO:0030003 180 0.015
regulation of cell growth GO:0001558 85 0.015
response to lipopolysaccharide GO:0032496 191 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
Rat
single organism intracellular transport GO:1902582 166 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
response to ethanol GO:0045471 162 0.015
forebrain development GO:0030900 98 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
Rat
regulation of body fluid levels GO:0050878 90 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
regulation of cell motility GO:2000145 131 0.015
Rat
regulation of locomotion GO:0040012 148 0.015
Rat
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.015
Rat
regulation of homotypic cell cell adhesion GO:0034110 4 0.015
reproductive system development GO:0061458 128 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
acute inflammatory response GO:0002526 58 0.015
positive regulation of camp biosynthetic process GO:0030819 28 0.015
regulation of isotype switching GO:0045191 1 0.015
protein homooligomerization GO:0051260 91 0.015
organ induction GO:0001759 1 0.015
cellular response to oxidative stress GO:0034599 76 0.014
developmental induction GO:0031128 2 0.014
urinary bladder smooth muscle contraction GO:0014832 4 0.014
coronary vasculature morphogenesis GO:0060977 3 0.014
dephosphorylation GO:0016311 98 0.014
membrane organization GO:0061024 94 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of saliva secretion GO:0046878 3 0.014
positive regulation of map kinase activity GO:0043406 46 0.014
negative regulation of cell communication GO:0010648 158 0.014
single organism cell adhesion GO:0098602 46 0.014
Rat
diaphragm contraction GO:0002086 2 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
Rat
hematopoietic progenitor cell differentiation GO:0002244 2 0.014
response to other organism GO:0051707 220 0.014
activation of protein kinase b activity GO:0032148 3 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
cellular response to external stimulus GO:0071496 118 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
carbohydrate homeostasis GO:0033500 75 0.014
immunoglobulin secretion GO:0048305 1 0.014
regulation of cardiac muscle contraction GO:0055117 17 0.014
b cell activation involved in immune response GO:0002312 1 0.014
cell cycle GO:0007049 101 0.014
regulation of transmembrane transport GO:0034762 122 0.014
sequestering of calcium ion GO:0051208 8 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
Rat
positive regulation of catabolic process GO:0009896 78 0.014
response to nutrient GO:0007584 248 0.014
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.013
immune effector process GO:0002252 53 0.013
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
negative regulation of developmental growth GO:0048640 15 0.013
organ formation GO:0048645 3 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013

Alox5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.051
disease of anatomical entity DOID:7 0 0.051
urinary system disease DOID:18 0 0.027
central nervous system disease DOID:331 0 0.022
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
essential hypertension DOID:10825 0 0.013
cardiovascular system disease DOID:1287 0 0.013
hypertension DOID:10763 0 0.013