Rattus norvegicus

0 known processes

Ap2m1

adaptor-related protein complex 2, mu 1 subunit

(Aliases: Ap50,MGC105352,Clapm1,mu2)

Ap2m1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to peptide hormone GO:0043434 278 0.547
response to peptide GO:1901652 292 0.439
cellular component biogenesis GO:0044085 368 0.371
cell cycle GO:0007049 101 0.298
response to insulin GO:0032868 133 0.287
single organism cellular localization GO:1902580 102 0.253
Human
cellular component assembly GO:0022607 360 0.245
cell cell signaling GO:0007267 335 0.237
cellular response to hormone stimulus GO:0032870 247 0.234
cellular response to peptide hormone stimulus GO:0071375 120 0.228
cellular response to nitrogen compound GO:1901699 210 0.171
histamine production involved in inflammatory response GO:0002349 3 0.166
organelle organization GO:0006996 266 0.155
macromolecular complex subunit organization GO:0043933 339 0.154
regulation of neurogenesis GO:0050767 247 0.151
neuron projection development GO:0031175 273 0.147
cellular response to insulin stimulus GO:0032869 81 0.143
protein complex biogenesis GO:0070271 263 0.141
response to inorganic substance GO:0010035 377 0.138
protein complex subunit organization GO:0071822 302 0.132
regulation of neuron differentiation GO:0045664 208 0.131
neural crest cell development GO:0014032 2 0.131
regulation of cell development GO:0060284 263 0.128
regulation of cellular component organization GO:0051128 368 0.120
Human
neuron development GO:0048666 286 0.117
cellular macromolecule localization GO:0070727 122 0.113
Human
protein complex assembly GO:0006461 263 0.105
cellular response to endogenous stimulus GO:0071495 377 0.105
regulation of transcription dna templated GO:0006355 374 0.104
regulation of dendrite development GO:0050773 59 0.101
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.100
regulation of apoptotic process GO:0042981 335 0.097
synaptic transmission GO:0007268 235 0.093
rna biosynthetic process GO:0032774 380 0.093
macromolecular complex assembly GO:0065003 273 0.092
cellular response to organonitrogen compound GO:0071417 197 0.090
regulation of cell differentiation GO:0045595 320 0.090
regulation of rna biosynthetic process GO:2001141 381 0.090
negative regulation of macromolecule metabolic process GO:0010605 260 0.089
organelle localization GO:0051640 55 0.088
dendrite development GO:0016358 72 0.087
cation homeostasis GO:0055080 195 0.087
negative regulation of gene expression GO:0010629 199 0.086
response to oxygen levels GO:0070482 265 0.080
cellular response to oxygen containing compound GO:1901701 386 0.079
response to transition metal nanoparticle GO:1990267 122 0.078
tube formation GO:0035148 3 0.078
defense response GO:0006952 194 0.077
secretion by cell GO:0032940 248 0.076
cellular cation homeostasis GO:0030003 180 0.075
mast cell degranulation GO:0043303 10 0.074
macromolecule localization GO:0033036 252 0.073
Human Fly
response to nutrient levels GO:0031667 370 0.072
mast cell activation GO:0045576 15 0.072
positive regulation of cellular component organization GO:0051130 200 0.070
ion homeostasis GO:0050801 212 0.070
aging GO:0007568 241 0.069
regulation of nervous system development GO:0051960 264 0.069
regulation of cell cycle GO:0051726 73 0.068
multi multicellular organism process GO:0044706 138 0.068
protein localization to organelle GO:0033365 57 0.067
protein transport GO:0015031 132 0.066
Fly
cellular calcium ion homeostasis GO:0006874 160 0.066
protein oligomerization GO:0051259 191 0.064
neuron differentiation GO:0030182 368 0.064
cellular chemical homeostasis GO:0055082 247 0.063
tissue development GO:0009888 252 0.063
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.063
intracellular protein transport GO:0006886 79 0.062
response to hypoxia GO:0001666 231 0.061
dendrite morphogenesis GO:0048813 43 0.061
chemical homeostasis GO:0048878 292 0.060
head development GO:0060322 247 0.059
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.059
protein phosphorylation GO:0006468 345 0.058
protein localization GO:0008104 191 0.058
Human Fly
regulation of cell proliferation GO:0042127 359 0.057
regulation of cell morphogenesis GO:0022604 77 0.057
regulation of anatomical structure morphogenesis GO:0022603 141 0.056
regulation of neuron projection development GO:0010975 161 0.056
regulation of cellular localization GO:0060341 263 0.055
Human
regulation of multicellular organismal development GO:2000026 376 0.055
histamine secretion by mast cell GO:0002553 3 0.055
negative regulation of metabolic process GO:0009892 331 0.055
calcium ion homeostasis GO:0055074 162 0.054
epithelium development GO:0060429 96 0.054
Fly
cellular protein localization GO:0034613 122 0.052
Human
cellular component movement GO:0006928 248 0.052
negative regulation of cellular metabolic process GO:0031324 281 0.052
cell morphogenesis involved in differentiation GO:0000904 119 0.052
cellular response to peptide GO:1901653 133 0.052
intracellular transport GO:0046907 185 0.052
regulation of organelle organization GO:0033043 80 0.051
cellular divalent inorganic cation homeostasis GO:0072503 162 0.051
regulation of rna metabolic process GO:0051252 391 0.051
mast cell mediated immunity GO:0002448 10 0.050
negative regulation of protein metabolic process GO:0051248 114 0.049
single organism reproductive process GO:0044702 297 0.049
Fly
regulation of actin filament based process GO:0032970 42 0.049
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.048
response to acid chemical GO:0001101 222 0.048
tissue morphogenesis GO:0048729 22 0.048
organic hydroxy compound metabolic process GO:1901615 115 0.047
hexose metabolic process GO:0019318 58 0.047
leukocyte activation GO:0045321 76 0.047
endocytosis GO:0006897 84 0.046
Fly
single organism biosynthetic process GO:0044711 342 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
positive regulation of cell death GO:0010942 184 0.045
nitrogen compound transport GO:0071705 229 0.045
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.044
inflammatory response GO:0006954 150 0.044
protein heterooligomerization GO:0051291 89 0.044
cell part morphogenesis GO:0032990 123 0.044
response to metal ion GO:0010038 253 0.043
cellular metal ion homeostasis GO:0006875 172 0.043
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.043
cellular amino acid metabolic process GO:0006520 107 0.042
regulation of cellular protein metabolic process GO:0032268 267 0.042
reproductive process GO:0022414 372 0.042
Fly
neural crest cell differentiation GO:0014033 2 0.042
cell type specific apoptotic process GO:0097285 134 0.041
leukocyte degranulation GO:0043299 12 0.041
regulation of anatomical structure size GO:0090066 135 0.040
transcription dna templated GO:0006351 377 0.040
establishment of organelle localization GO:0051656 37 0.040
cell projection morphogenesis GO:0048858 123 0.039
membrane organization GO:0061024 94 0.039
Human
dendritic spine morphogenesis GO:0060997 9 0.038
myeloid leukocyte activation GO:0002274 36 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.038
positive regulation of cell development GO:0010720 176 0.037
cell cycle process GO:0022402 57 0.037
neuron death GO:0070997 127 0.037
carbohydrate metabolic process GO:0005975 130 0.037
regulation of protein modification process GO:0031399 194 0.036
response to decreased oxygen levels GO:0036293 237 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
Fly
negative regulation of biosynthetic process GO:0009890 168 0.036
neural crest cell migration GO:0001755 1 0.035
response to external biotic stimulus GO:0043207 221 0.035
positive regulation of developmental process GO:0051094 283 0.035
immune system process GO:0002376 204 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cell activation GO:0001775 97 0.034
regulation of neuron apoptotic process GO:0043523 83 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
brain development GO:0007420 247 0.033
negative regulation of cell proliferation GO:0008285 119 0.033
response to alkaloid GO:0043279 132 0.033
organic hydroxy compound transport GO:0015850 77 0.032
cell projection organization GO:0030030 302 0.032
cellular ketone metabolic process GO:0042180 51 0.032
cation transport GO:0006812 382 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.032
positive regulation of nervous system development GO:0051962 178 0.031
single organism intracellular transport GO:1902582 166 0.031
cellular ion homeostasis GO:0006873 184 0.031
lysosome localization GO:0032418 10 0.031
cellular amine metabolic process GO:0044106 38 0.030
negative regulation of nervous system development GO:0051961 79 0.030
rna metabolic process GO:0016070 406 0.030
response to corticosteroid GO:0031960 235 0.030
protein localization to chromosome centromeric region GO:0071459 1 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
response to biotic stimulus GO:0009607 226 0.030
reproductive system development GO:0061458 128 0.029
central nervous system development GO:0007417 311 0.029
gastrulation GO:0007369 2 0.029
regulation of cell projection organization GO:0031344 175 0.029
regulation of meiotic cell cycle GO:0051445 3 0.029
neuron neuron synaptic transmission GO:0007270 60 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
response to extracellular stimulus GO:0009991 380 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
embryo development GO:0009790 49 0.028
myeloid leukocyte mediated immunity GO:0002444 12 0.028
cytosolic calcium ion homeostasis GO:0051480 140 0.028
cellular homeostasis GO:0019725 252 0.028
programmed cell death GO:0012501 392 0.027
chemotaxis GO:0006935 66 0.027
response to hexose GO:0009746 144 0.027
gliogenesis GO:0042063 93 0.027
regeneration GO:0031099 163 0.027
negative regulation of rna metabolic process GO:0051253 123 0.027
proteolysis GO:0006508 175 0.027
transmembrane transport GO:0055085 412 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
response to amino acid GO:0043200 75 0.026
growth GO:0040007 165 0.025
response to glucose GO:0009749 136 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
regulation of metal ion transport GO:0010959 118 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
tube development GO:0035295 89 0.024
gonad development GO:0008406 104 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
Fly
establishment of protein localization GO:0045184 141 0.024
Fly
immune effector process GO:0002252 53 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
establishment of cell polarity GO:0030010 6 0.024
reproductive structure development GO:0048608 128 0.023
secretion GO:0046903 307 0.023
morphogenesis of an epithelium GO:0002009 20 0.023
homeostatic process GO:0042592 331 0.023
metal ion homeostasis GO:0055065 186 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
hormone transport GO:0009914 121 0.023
positive regulation of cell projection organization GO:0031346 111 0.023
response to ethanol GO:0045471 162 0.023
neuron apoptotic process GO:0051402 88 0.023
regulation of cellular component movement GO:0051270 150 0.023
organophosphate biosynthetic process GO:0090407 143 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
tissue regeneration GO:0042246 36 0.022
circulatory system process GO:0003013 183 0.022
sensory perception of pain GO:0019233 73 0.022
vesicle mediated transport GO:0016192 181 0.022
Fly
regulation of hormone levels GO:0010817 187 0.021
extracellular fibril organization GO:0043206 1 0.021
response to wounding GO:0009611 254 0.021
protein localization to membrane GO:0072657 36 0.021
Human
positive regulation of gene expression GO:0010628 244 0.021
mitotic cell cycle process GO:1903047 35 0.021
axonogenesis GO:0007409 71 0.021
regulation of neuron death GO:1901214 115 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
anion transport GO:0006820 178 0.021
cellular component morphogenesis GO:0032989 155 0.021
multi organism reproductive process GO:0044703 262 0.020
Fly
response to carbohydrate GO:0009743 183 0.020
regulation of dendritic spine morphogenesis GO:0061001 6 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
eye morphogenesis GO:0048592 4 0.020
response to toxic substance GO:0009636 133 0.019
regulation of programmed cell death GO:0043067 341 0.019
reproduction GO:0000003 245 0.019
Fly
regulation of membrane potential GO:0042391 110 0.019
cell motility GO:0048870 202 0.019
vesicle localization GO:0051648 33 0.019
amine metabolic process GO:0009308 38 0.019
organ morphogenesis GO:0009887 75 0.019
leukocyte activation involved in immune response GO:0002366 16 0.019
cytoskeleton dependent cytokinesis GO:0061640 2 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
organic anion transport GO:0015711 132 0.019
response to glucocorticoid GO:0051384 223 0.019
regulation of synaptic transmission GO:0050804 141 0.019
salivary gland development GO:0007431 3 0.019
ion transmembrane transport GO:0034220 365 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
mitotic spindle organization GO:0007052 2 0.018
asymmetric stem cell division GO:0098722 2 0.018
histamine secretion involved in inflammatory response GO:0002441 3 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
axon development GO:0061564 96 0.018
positive regulation of transport GO:0051050 245 0.018
neuron projection morphogenesis GO:0048812 122 0.018
divalent metal ion transport GO:0070838 132 0.018
negative regulation of signaling GO:0023057 157 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
establishment of protein localization to membrane GO:0090150 16 0.017
learning or memory GO:0007611 90 0.017
response to other organism GO:0051707 220 0.017
immune response GO:0006955 104 0.017
response to nutrient GO:0007584 248 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
nucleic acid templated transcription GO:0097659 379 0.017
response to estrogen GO:0043627 232 0.017
regulation of locomotion GO:0040012 148 0.017
protein targeting GO:0006605 61 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
regulation of dendrite morphogenesis GO:0048814 33 0.016
regulation of cell migration GO:0030334 128 0.016
regulation of phosphorylation GO:0042325 248 0.016
response to growth factor GO:0070848 189 0.016
catabolic process GO:0009056 351 0.016
female pregnancy GO:0007565 122 0.016
phospholipid biosynthetic process GO:0008654 29 0.016
production of molecular mediator involved in inflammatory response GO:0002532 5 0.016
camp metabolic process GO:0046058 63 0.016
sensory perception GO:0007600 101 0.016
catecholamine transport GO:0051937 37 0.016
actin filament depolymerization GO:0030042 3 0.015
spindle organization GO:0007051 2 0.015
dna metabolic process GO:0006259 96 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
multicellular organismal signaling GO:0035637 44 0.015
organic acid metabolic process GO:0006082 292 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
histamine secretion GO:0001821 8 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
response to estradiol GO:0032355 164 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
positive regulation of protein depolymerization GO:1901881 3 0.015
hormone secretion GO:0046879 115 0.015
negative regulation of transport GO:0051051 136 0.014
phospholipid metabolic process GO:0006644 61 0.014
associative learning GO:0008306 19 0.014
regulation of extent of cell growth GO:0061387 25 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
lipid biosynthetic process GO:0008610 128 0.014
learning GO:0007612 33 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
eye development GO:0001654 50 0.014
placenta development GO:0001890 22 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
regulation of ion transport GO:0043269 245 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
actin filament based process GO:0030029 86 0.014
response to virus GO:0009615 17 0.014
response to monosaccharide GO:0034284 159 0.014
axon cargo transport GO:0008088 1 0.013
organ regeneration GO:0031100 101 0.013
olfactory behavior GO:0042048 2 0.013
negative regulation of cell death GO:0060548 229 0.013
small molecule biosynthetic process GO:0044283 124 0.013
purine containing compound metabolic process GO:0072521 253 0.013
lipid metabolic process GO:0006629 283 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular lipid metabolic process GO:0044255 208 0.013
cytoskeleton organization GO:0007010 111 0.013
protein targeting to plasma membrane GO:0072661 4 0.013
positive regulation of molecular function GO:0044093 230 0.013
neurological system process GO:0050877 219 0.013
developmental process involved in reproduction GO:0003006 159 0.013
Fly
viral transcription GO:0019083 2 0.013
single organism membrane organization GO:0044802 74 0.013
Human
positive regulation of signal transduction GO:0009967 175 0.013
synaptic vesicle endocytosis GO:0048488 4 0.013
circadian rhythm GO:0007623 88 0.013
muscle organ development GO:0007517 50 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
response to ammonium ion GO:0060359 71 0.013
regulation of cell motility GO:2000145 131 0.013
regulation of protein metabolic process GO:0051246 289 0.013
sequestering of metal ion GO:0051238 9 0.013
regulation of blood pressure GO:0008217 83 0.013
regulation of cell growth GO:0001558 85 0.012
negative regulation of cell division GO:0051782 1 0.012
glycerolipid metabolic process GO:0046486 67 0.012
anterior posterior pattern specification GO:0009952 1 0.012
development of primary sexual characteristics GO:0045137 107 0.012
oxoacid metabolic process GO:0043436 290 0.012
glucose metabolic process GO:0006006 52 0.012
sensory organ development GO:0007423 74 0.012
sequestering of calcium ion GO:0051208 8 0.012
glial cell differentiation GO:0010001 65 0.012
biological adhesion GO:0022610 110 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
negative regulation of neuron death GO:1901215 69 0.012
cell morphogenesis GO:0000902 142 0.012
actin cytoskeleton organization GO:0030036 73 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
Human
cell activation involved in immune response GO:0002263 16 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cellular response to external stimulus GO:0071496 118 0.012
regulation of molecular function GO:0065009 398 0.012
cellular catabolic process GO:0044248 295 0.012
regulation of cellular component size GO:0032535 51 0.012
positive regulation of neuron death GO:1901216 43 0.012
neural precursor cell proliferation GO:0061351 23 0.011
mast cell activation involved in immune response GO:0002279 10 0.011
cognition GO:0050890 92 0.011
heart morphogenesis GO:0003007 3 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
axis specification GO:0009798 4 0.011
protein processing GO:0016485 68 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
odontogenesis GO:0042476 32 0.011
neuron projection guidance GO:0097485 24 0.011
localization of cell GO:0051674 202 0.011
nucleotide metabolic process GO:0009117 279 0.011
signal release GO:0023061 145 0.011
cellular response to hypoxia GO:0071456 51 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
dorsal ventral pattern formation GO:0009953 4 0.011
regulation of actin filament depolymerization GO:0030834 2 0.011
cell cycle checkpoint GO:0000075 2 0.011
cell migration GO:0016477 197 0.011
positive regulation of biosynthetic process GO:0009891 319 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
negative regulation of cell communication GO:0010648 158 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
chemosensory behavior GO:0007635 2 0.010
negative regulation of developmental process GO:0051093 125 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010

Ap2m1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.119
nervous system disease DOID:863 0 0.119
central nervous system disease DOID:331 0 0.016
sensory system disease DOID:0050155 0 0.013
epilepsy syndrome DOID:1826 0 0.012
brain disease DOID:936 0 0.012
electroclinical syndrome DOID:0050701 0 0.012