Rattus norvegicus

0 known processes

Ap2s1

adaptor-related protein complex 2, sigma 1 subunit

(Aliases: Ap17)

Ap2s1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of carbohydrate catabolic process GO:0043470 14 0.260
positive regulation of cellular component organization GO:0051130 200 0.258
regulation of cellular component organization GO:0051128 368 0.251
cellular catabolic process GO:0044248 295 0.209
cell projection organization GO:0030030 302 0.186
response to inorganic substance GO:0010035 377 0.184
regulation of ryanodine sensitive calcium release channel activity GO:0060314 5 0.173
cellular protein localization GO:0034613 122 0.166
purine ribonucleotide metabolic process GO:0009150 227 0.159
response to metal ion GO:0010038 253 0.147
regulation of cell development GO:0060284 263 0.147
transmembrane transport GO:0055085 412 0.145
regulation of cell projection organization GO:0031344 175 0.143
neuron development GO:0048666 286 0.142
organophosphate metabolic process GO:0019637 370 0.141
response to ethanol GO:0045471 162 0.141
nucleoside phosphate metabolic process GO:0006753 283 0.137
regulation of cell differentiation GO:0045595 320 0.135
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.129
single organism carbohydrate metabolic process GO:0044723 118 0.127
response to glucocorticoid GO:0051384 223 0.114
positive regulation of transport GO:0051050 245 0.112
membrane organization GO:0061024 94 0.110
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.108
metal ion homeostasis GO:0055065 186 0.106
nucleobase containing small molecule metabolic process GO:0055086 316 0.105
positive regulation of phosphate metabolic process GO:0045937 262 0.104
ribose phosphate metabolic process GO:0019693 235 0.103
nucleotide metabolic process GO:0009117 279 0.103
ribonucleoside triphosphate catabolic process GO:0009203 122 0.103
carbohydrate derivative metabolic process GO:1901135 346 0.102
neuron differentiation GO:0030182 368 0.101
response to oxidative stress GO:0006979 186 0.100
entrainment of circadian clock GO:0009649 3 0.096
organophosphate biosynthetic process GO:0090407 143 0.095
purine nucleoside triphosphate metabolic process GO:0009144 141 0.090
response to transition metal nanoparticle GO:1990267 122 0.090
regulation of neuron differentiation GO:0045664 208 0.087
protein localization GO:0008104 191 0.086
Fly
regulation of neuron projection development GO:0010975 161 0.085
regulation of nervous system development GO:0051960 264 0.082
ion transmembrane transport GO:0034220 365 0.081
regulation of multicellular organismal development GO:2000026 376 0.080
response to estradiol GO:0032355 164 0.079
neuron projection development GO:0031175 273 0.079
response to corticosteroid GO:0031960 235 0.077
catabolic process GO:0009056 351 0.077
nucleoside catabolic process GO:0009164 126 0.076
ribonucleoside metabolic process GO:0009119 174 0.075
cation homeostasis GO:0055080 195 0.074
regulation of phosphate metabolic process GO:0019220 349 0.073
rna biosynthetic process GO:0032774 380 0.072
macromolecule localization GO:0033036 252 0.071
Fly
metal ion transport GO:0030001 289 0.068
protein transport GO:0015031 132 0.068
Fly
ribose phosphate biosynthetic process GO:0046390 87 0.067
cation transport GO:0006812 382 0.067
positive regulation of cell differentiation GO:0045597 217 0.065
response to peptide GO:1901652 292 0.065
positive regulation of cell development GO:0010720 176 0.064
positive regulation of multicellular organismal process GO:0051240 387 0.063
protein complex subunit organization GO:0071822 302 0.063
regulation of locomotion GO:0040012 148 0.063
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
carbohydrate catabolic process GO:0016052 40 0.061
carbohydrate derivative catabolic process GO:1901136 147 0.060
circadian regulation of gene expression GO:0032922 3 0.059
positive regulation of developmental process GO:0051094 283 0.059
regulation of catalytic activity GO:0050790 304 0.058
tissue development GO:0009888 252 0.058
inorganic cation transmembrane transport GO:0098662 202 0.057
purine containing compound metabolic process GO:0072521 253 0.057
regulation of transcription dna templated GO:0006355 374 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.056
neuron death GO:0070997 127 0.056
cellular metal ion homeostasis GO:0006875 172 0.055
purine nucleoside triphosphate catabolic process GO:0009146 122 0.055
head development GO:0060322 247 0.054
single organism catabolic process GO:0044712 283 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.054
purine containing compound catabolic process GO:0072523 138 0.054
cell migration GO:0016477 197 0.054
purine ribonucleotide catabolic process GO:0009154 136 0.053
carbohydrate derivative biosynthetic process GO:1901137 124 0.052
positive regulation of cell death GO:0010942 184 0.051
cellular ion homeostasis GO:0006873 184 0.051
intracellular signal transduction GO:0035556 314 0.051
purine ribonucleoside metabolic process GO:0046128 168 0.050
ribonucleoside triphosphate metabolic process GO:0009199 141 0.049
immune response GO:0006955 104 0.049
regulation of synaptic transmission GO:0050804 141 0.048
apoptotic process GO:0006915 381 0.048
cell cell signaling GO:0007267 335 0.048
nucleoside phosphate catabolic process GO:1901292 140 0.047
regulation of purine nucleotide metabolic process GO:1900542 115 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.047
response to peptide hormone GO:0043434 278 0.047
regulation of cell migration GO:0030334 128 0.047
chemical homeostasis GO:0048878 292 0.046
reproductive system development GO:0061458 128 0.046
cellular homeostasis GO:0019725 252 0.044
multicellular organism reproduction GO:0032504 233 0.044
organonitrogen compound catabolic process GO:1901565 179 0.044
cell cycle checkpoint GO:0000075 2 0.043
protein localization to membrane GO:0072657 36 0.043
reproduction GO:0000003 245 0.043
response to ketone GO:1901654 182 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.043
cell morphogenesis involved in differentiation GO:0000904 119 0.040
multicellular organismal reproductive process GO:0048609 233 0.040
positive regulation of response to stimulus GO:0048584 285 0.040
cellular calcium ion homeostasis GO:0006874 160 0.039
ras protein signal transduction GO:0007265 29 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.039
cellular response to oxygen containing compound GO:1901701 386 0.038
transcription dna templated GO:0006351 377 0.038
cytosolic calcium ion homeostasis GO:0051480 140 0.038
cellular cation homeostasis GO:0030003 180 0.037
response to light stimulus GO:0009416 52 0.037
regulation of nucleotide metabolic process GO:0006140 117 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.037
cellular component assembly GO:0022607 360 0.036
single organism reproductive process GO:0044702 297 0.036
positive regulation of neuron differentiation GO:0045666 126 0.036
oxidation reduction process GO:0055114 304 0.035
purine ribonucleoside catabolic process GO:0046130 124 0.035
positive regulation of nervous system development GO:0051962 178 0.035
regulation of catabolic process GO:0009894 113 0.035
ribonucleoside diphosphate metabolic process GO:0009185 10 0.035
regulation of anatomical structure morphogenesis GO:0022603 141 0.035
inorganic ion transmembrane transport GO:0098660 229 0.034
response to oxygen levels GO:0070482 265 0.034
muscle organ development GO:0007517 50 0.034
angiogenesis GO:0001525 53 0.034
synaptic transmission GO:0007268 235 0.034
organic substance catabolic process GO:1901575 316 0.034
locomotion GO:0040011 237 0.033
brain development GO:0007420 247 0.033
regulation of neurogenesis GO:0050767 247 0.033
positive regulation of molecular function GO:0044093 230 0.033
muscle tissue development GO:0060537 58 0.032
regulation of neuronal synaptic plasticity GO:0048168 31 0.032
single organism membrane organization GO:0044802 74 0.032
cellular response to stress GO:0033554 269 0.032
ribonucleotide metabolic process GO:0009259 231 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.032
striated muscle tissue development GO:0014706 58 0.032
cellular component morphogenesis GO:0032989 155 0.032
multi organism reproductive process GO:0044703 262 0.031
positive regulation of monooxygenase activity GO:0032770 5 0.031
intracellular transport GO:0046907 185 0.031
organic cyclic compound catabolic process GO:1901361 175 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
regulation of protein localization GO:0032880 81 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
cellular chemical homeostasis GO:0055082 247 0.030
positive regulation of neuron death GO:1901216 43 0.030
regulation of hydrolase activity GO:0051336 143 0.029
organelle organization GO:0006996 266 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
dephosphorylation GO:0016311 98 0.029
cell projection morphogenesis GO:0048858 123 0.029
regulation of programmed cell death GO:0043067 341 0.029
reproductive structure development GO:0048608 128 0.029
nucleoside monophosphate catabolic process GO:0009125 56 0.028
protein complex assembly GO:0006461 263 0.028
response to growth factor GO:0070848 189 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
regulation of calcium ion transport GO:0051924 77 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
programmed cell death GO:0012501 392 0.027
heart morphogenesis GO:0003007 3 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
cellular glucan metabolic process GO:0006073 23 0.027
response to other organism GO:0051707 220 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
regulation of long term neuronal synaptic plasticity GO:0048169 15 0.026
axon development GO:0061564 96 0.026
cyclic nucleotide biosynthetic process GO:0009190 63 0.026
developmental process involved in reproduction GO:0003006 159 0.026
regulation of purine nucleotide catabolic process GO:0033121 65 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
circulatory system development GO:0072359 134 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
guanosine containing compound metabolic process GO:1901068 74 0.025
cell substrate adhesion GO:0031589 29 0.025
regulation of nucleoside metabolic process GO:0009118 66 0.025
circulatory system process GO:0003013 183 0.025
response to biotic stimulus GO:0009607 226 0.025
regulation of cyclase activity GO:0031279 21 0.025
regulation of immune system process GO:0002682 123 0.025
protein phosphorylation GO:0006468 345 0.025
heterocycle catabolic process GO:0046700 167 0.025
response to testosterone GO:0033574 55 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
regulation of apoptotic process GO:0042981 335 0.024
sensory organ development GO:0007423 74 0.024
regulation of heart growth GO:0060420 12 0.024
regulation of cellular component biogenesis GO:0044087 86 0.024
secretion GO:0046903 307 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
regulation of vesicle mediated transport GO:0060627 81 0.023
central nervous system development GO:0007417 311 0.023
carbohydrate metabolic process GO:0005975 130 0.023
response to extracellular stimulus GO:0009991 380 0.023
nucleic acid templated transcription GO:0097659 379 0.023
cell type specific apoptotic process GO:0097285 134 0.023
response to nutrient GO:0007584 248 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
nucleoside metabolic process GO:0009116 179 0.023
single organism intracellular transport GO:1902582 166 0.023
regulation of high voltage gated calcium channel activity GO:1901841 3 0.022
calcium ion homeostasis GO:0055074 162 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
proteolysis GO:0006508 175 0.022
glycogen biosynthetic process GO:0005978 15 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
male gamete generation GO:0048232 99 0.022
cytoskeleton organization GO:0007010 111 0.022
protein dephosphorylation GO:0006470 38 0.022
muscle system process GO:0003012 115 0.022
glycosyl compound metabolic process GO:1901657 182 0.021
organic anion transport GO:0015711 132 0.021
regulation of phosphorylation GO:0042325 248 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
hair cycle process GO:0022405 2 0.021
hexose metabolic process GO:0019318 58 0.021
positive regulation of oxidoreductase activity GO:0051353 7 0.020
positive regulation of gene expression GO:0010628 244 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
cell part morphogenesis GO:0032990 123 0.020
negative regulation of cell death GO:0060548 229 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
positive regulation of organelle organization GO:0010638 48 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of synaptic plasticity GO:0048167 70 0.020
positive regulation of glycolytic process GO:0045821 5 0.020
response to reactive oxygen species GO:0000302 120 0.019
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.019
regulation of muscle system process GO:0090257 79 0.019
aging GO:0007568 241 0.019
response to wounding GO:0009611 254 0.019
response to radiation GO:0009314 137 0.019
organic acid transport GO:0015849 116 0.019
organophosphate catabolic process GO:0046434 148 0.019
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
regulation of neuron death GO:1901214 115 0.018
regulation of oxidoreductase activity GO:0051341 11 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of immune system process GO:0002684 90 0.018
atp catabolic process GO:0006200 54 0.018
aromatic compound catabolic process GO:0019439 168 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
sequestering of metal ion GO:0051238 9 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of signaling GO:0023056 270 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
response to decreased oxygen levels GO:0036293 237 0.017
calcium ion transport GO:0006816 131 0.017
glucose metabolic process GO:0006006 52 0.017
cardiocyte differentiation GO:0035051 22 0.017
localization of cell GO:0051674 202 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
regulation of dna metabolic process GO:0051052 60 0.017
sexual reproduction GO:0019953 148 0.016
response to alkaloid GO:0043279 132 0.016
regulation of signal transduction GO:0009966 318 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
cardiac muscle cell development GO:0055013 16 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
regulation of cellular response to growth factor stimulus GO:0090287 15 0.016
response to mineralocorticoid GO:0051385 49 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
cytoplasmic transport GO:0016482 115 0.016
homeostatic process GO:0042592 331 0.016
regulation of molecular function GO:0065009 398 0.016
protein autophosphorylation GO:0046777 66 0.016
carboxylic acid transport GO:0046942 115 0.015
response to nutrient levels GO:0031667 370 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
regulation of cardiac muscle tissue development GO:0055024 12 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
ion homeostasis GO:0050801 212 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
divalent metal ion transport GO:0070838 132 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
muscle structure development GO:0061061 87 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
embryo development GO:0009790 49 0.015
camp biosynthetic process GO:0006171 47 0.015
protein complex biogenesis GO:0070271 263 0.015
gtp metabolic process GO:0046039 72 0.015
camp metabolic process GO:0046058 63 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
autophagy GO:0006914 19 0.014
phospholipid biosynthetic process GO:0008654 29 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
cation transmembrane transport GO:0098655 263 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
cellular response to external stimulus GO:0071496 118 0.014
cellular amine metabolic process GO:0044106 38 0.014
spermatogenesis GO:0007283 99 0.014
cell motility GO:0048870 202 0.014
purine ribonucleotide biosynthetic process GO:0009152 81 0.014
second messenger mediated signaling GO:0019932 51 0.014
epithelium development GO:0060429 96 0.014
axis specification GO:0009798 4 0.014
regulation of organelle organization GO:0033043 80 0.013
response to mechanical stimulus GO:0009612 134 0.013
protein targeting GO:0006605 61 0.013
sequestering of calcium ion GO:0051208 8 0.013
regulation of meiotic cell cycle GO:0051445 3 0.013
regulation of cell growth GO:0001558 85 0.013
protein targeting to membrane GO:0006612 11 0.013
vesicle mediated transport GO:0016192 181 0.013
Fly
receptor metabolic process GO:0043112 18 0.013
positive regulation of lyase activity GO:0051349 15 0.013
cardiovascular system development GO:0072358 134 0.013
glycosaminoglycan biosynthetic process GO:0006024 4 0.013
regulation of cellular component size GO:0032535 51 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
purine nucleoside monophosphate catabolic process GO:0009128 55 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
body fluid secretion GO:0007589 41 0.012
eye development GO:0001654 50 0.012
response to estrogen GO:0043627 232 0.012
regulation of body fluid levels GO:0050878 90 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
divalent inorganic cation transport GO:0072511 134 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
positive regulation of cell communication GO:0010647 271 0.012
oxoacid metabolic process GO:0043436 290 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of muscle tissue development GO:1901861 25 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
single organism carbohydrate catabolic process GO:0044724 40 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
photoperiodism GO:0009648 4 0.012
response to calcium ion GO:0051592 59 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
blood vessel development GO:0001568 69 0.012
response to chromate GO:0046687 3 0.011
physiological muscle hypertrophy GO:0003298 13 0.011
intracellular protein transport GO:0006886 79 0.011
nucleoside diphosphate metabolic process GO:0009132 14 0.011
single organism biosynthetic process GO:0044711 342 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
regulation of protein modification process GO:0031399 194 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
response to acid chemical GO:0001101 222 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
positive regulation of growth GO:0045927 55 0.011
positive regulation of cell growth involved in cardiac muscle cell development GO:0061051 5 0.011
positive regulation of catabolic process GO:0009896 78 0.011
cardiac cell development GO:0055006 16 0.011
positive regulation of signal transduction GO:0009967 175 0.011
response to fatty acid GO:0070542 65 0.011
cellular component biogenesis GO:0044085 368 0.011
reproductive process GO:0022414 372 0.011
sensory perception of pain GO:0019233 73 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
biological adhesion GO:0022610 110 0.011
establishment of protein localization GO:0045184 141 0.011
Fly
blood vessel morphogenesis GO:0048514 58 0.011
regulation of cellular localization GO:0060341 263 0.011
regulation of metal ion transport GO:0010959 118 0.011
response to electrical stimulus GO:0051602 56 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
regulation of anatomical structure size GO:0090066 135 0.011
amine metabolic process GO:0009308 38 0.011
establishment of protein localization to membrane GO:0090150 16 0.011
regulation of dendritic spine morphogenesis GO:0061001 6 0.011
muscle contraction GO:0006936 88 0.011
molting cycle process GO:0022404 2 0.011
positive regulation of camp biosynthetic process GO:0030819 28 0.010
positive regulation of cell migration GO:0030335 96 0.010
pyrimidine nucleoside triphosphate metabolic process GO:0009147 4 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
generation of precursor metabolites and energy GO:0006091 62 0.010
cell morphogenesis GO:0000902 142 0.010
actin filament based process GO:0030029 86 0.010
endomembrane system organization GO:0010256 48 0.010
positive regulation of protein modification process GO:0031401 142 0.010
single organism organelle organization GO:1902589 180 0.010
anion transmembrane transport GO:0098656 77 0.010
positive regulation of cell growth GO:0030307 44 0.010
branching morphogenesis of an epithelial tube GO:0048754 14 0.010
calcium ion transport into cytosol GO:0060402 38 0.010

Ap2s1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011