Rattus norvegicus

0 known processes

Apobec2

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2

Apobec2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
homeostatic process GO:0042592 331 0.280
muscle system process GO:0003012 115 0.276
regulation of muscle contraction GO:0006937 53 0.210
ion homeostasis GO:0050801 212 0.191
cellular response to stress GO:0033554 269 0.171
cellular metal ion homeostasis GO:0006875 172 0.166
regulation of cellular component organization GO:0051128 368 0.164
regulation of system process GO:0044057 208 0.158
divalent inorganic cation homeostasis GO:0072507 165 0.155
apoptotic process GO:0006915 381 0.144
cardiac muscle contraction GO:0060048 27 0.141
heart contraction GO:0060047 57 0.138
regulation of ion transport GO:0043269 245 0.124
regulation of cardiac muscle contraction GO:0055117 17 0.122
regulation of muscle system process GO:0090257 79 0.120
metal ion transport GO:0030001 289 0.120
striated muscle contraction GO:0006941 44 0.117
cellular response to nitrogen compound GO:1901699 210 0.116
Rat
response to inorganic substance GO:0010035 377 0.110
Rat
cellular cation homeostasis GO:0030003 180 0.107
cellular component movement GO:0006928 248 0.106
response to hypoxia GO:0001666 231 0.105
cellular calcium ion homeostasis GO:0006874 160 0.104
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.100
regulation of rna biosynthetic process GO:2001141 381 0.098
cellular ion homeostasis GO:0006873 184 0.097
regulation of metal ion transport GO:0010959 118 0.096
regulation of nucleic acid templated transcription GO:1903506 380 0.094
response to nutrient levels GO:0031667 370 0.092
transcription dna templated GO:0006351 377 0.091
negative regulation of cell death GO:0060548 229 0.088
cellular chemical homeostasis GO:0055082 247 0.088
regulation of programmed cell death GO:0043067 341 0.087
calcium ion homeostasis GO:0055074 162 0.083
rna metabolic process GO:0016070 406 0.083
Rat
immune system process GO:0002376 204 0.082
Rat
actin mediated cell contraction GO:0070252 12 0.080
regulation of striated muscle contraction GO:0006942 21 0.080
negative regulation of apoptotic process GO:0043066 181 0.080
regulation of cell differentiation GO:0045595 320 0.080
neuron differentiation GO:0030182 368 0.078
circulatory system process GO:0003013 183 0.077
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.077
rna biosynthetic process GO:0032774 380 0.075
regulation of neuron differentiation GO:0045664 208 0.075
cellular divalent inorganic cation homeostasis GO:0072503 162 0.070
muscle contraction GO:0006936 88 0.070
locomotion GO:0040011 237 0.069
chemical homeostasis GO:0048878 292 0.069
regulation of multicellular organismal development GO:2000026 376 0.068
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.065
nucleic acid templated transcription GO:0097659 379 0.063
catabolic process GO:0009056 351 0.062
Rat
cellular homeostasis GO:0019725 252 0.062
regulation of neuron projection development GO:0010975 161 0.061
cation transport GO:0006812 382 0.061
positive regulation of developmental process GO:0051094 283 0.060
intracellular signal transduction GO:0035556 314 0.060
regulation of heart contraction GO:0008016 48 0.059
cellular ketone metabolic process GO:0042180 51 0.058
cation homeostasis GO:0055080 195 0.058
metal ion homeostasis GO:0055065 186 0.058
mapk cascade GO:0000165 140 0.058
central nervous system development GO:0007417 311 0.058
regulation of cell projection organization GO:0031344 175 0.057
response to estradiol GO:0032355 164 0.057
positive regulation of multicellular organismal process GO:0051240 387 0.057
transmembrane transport GO:0055085 412 0.056
programmed cell death GO:0012501 392 0.056
neuron projection development GO:0031175 273 0.056
regulation of potassium ion transport GO:0043266 29 0.055
positive regulation of biosynthetic process GO:0009891 319 0.055
response to wounding GO:0009611 254 0.054
signal transduction by phosphorylation GO:0023014 144 0.054
regulation of cellular component movement GO:0051270 150 0.053
ion transmembrane transport GO:0034220 365 0.053
defense response GO:0006952 194 0.053
Rat
endoplasmic reticulum to cytosol transport GO:1903513 4 0.053
response to mechanical stimulus GO:0009612 134 0.053
muscle structure development GO:0061061 87 0.052
cellular response to organic cyclic compound GO:0071407 202 0.052
potassium ion transport GO:0006813 97 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
cation transmembrane transport GO:0098655 263 0.051
circulatory system development GO:0072359 134 0.051
actin filament based movement GO:0030048 16 0.051
response to purine containing compound GO:0014074 126 0.051
regulation of apoptotic process GO:0042981 335 0.050
response to estrogen GO:0043627 232 0.048
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.048
cell projection organization GO:0030030 302 0.047
regulation of rna metabolic process GO:0051252 391 0.047
response to decreased oxygen levels GO:0036293 237 0.046
muscle cell differentiation GO:0042692 52 0.046
cellular component assembly GO:0022607 360 0.046
regulation of transcription dna templated GO:0006355 374 0.046
cytosolic calcium ion homeostasis GO:0051480 140 0.045
regulation of homeostatic process GO:0032844 101 0.045
positive regulation of molecular function GO:0044093 230 0.045
response to toxic substance GO:0009636 133 0.045
single organism organelle organization GO:1902589 180 0.044
regulation of transmembrane transporter activity GO:0022898 49 0.041
negative regulation of multicellular organismal process GO:0051241 203 0.041
positive regulation of cell differentiation GO:0045597 217 0.041
divalent inorganic cation transport GO:0072511 134 0.041
inorganic cation transmembrane transport GO:0098662 202 0.040
negative regulation of programmed cell death GO:0043069 183 0.040
behavior GO:0007610 205 0.039
muscle tissue development GO:0060537 58 0.039
response to biotic stimulus GO:0009607 226 0.039
Rat
head development GO:0060322 247 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
Rat
amine metabolic process GO:0009308 38 0.038
blood circulation GO:0008015 183 0.038
regulation of cell development GO:0060284 263 0.037
striated muscle cell development GO:0055002 26 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
negative regulation of metabolic process GO:0009892 331 0.036
multicellular organismal signaling GO:0035637 44 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
cellular component biogenesis GO:0044085 368 0.036
heart development GO:0007507 72 0.036
cellular response to oxygen containing compound GO:1901701 386 0.035
Rat
regulation of blood circulation GO:1903522 110 0.035
heart process GO:0003015 57 0.034
cellular response to lipid GO:0071396 201 0.034
response to oxygen levels GO:0070482 265 0.034
regulation of protein metabolic process GO:0051246 289 0.033
response to extracellular stimulus GO:0009991 380 0.033
transmission of nerve impulse GO:0019226 42 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
regulation of nervous system development GO:0051960 264 0.033
positive regulation of cellular component organization GO:0051130 200 0.032
neuron apoptotic process GO:0051402 88 0.032
regulation of actin filament based movement GO:1903115 12 0.032
regulation of mapk cascade GO:0043408 116 0.032
sequestering of calcium ion GO:0051208 8 0.031
regulation of molecular function GO:0065009 398 0.031
leukocyte activation GO:0045321 76 0.031
protein localization GO:0008104 191 0.031
regulation of cell proliferation GO:0042127 359 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
response to bacterium GO:0009617 200 0.030
response to peptide GO:1901652 292 0.030
Rat
action potential GO:0001508 54 0.030
regulation of blood vessel size GO:0050880 89 0.030
regulation of calcium ion transport GO:0051924 77 0.030
inflammatory response GO:0006954 150 0.030
cytoskeleton organization GO:0007010 111 0.030
carbohydrate metabolic process GO:0005975 130 0.029
response to metal ion GO:0010038 253 0.029
Rat
cell type specific apoptotic process GO:0097285 134 0.029
muscle cell proliferation GO:0033002 84 0.029
membrane depolarization during action potential GO:0086010 1 0.029
positive regulation of transport GO:0051050 245 0.029
negative regulation of transport GO:0051051 136 0.028
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
ventricular cardiac muscle cell action potential GO:0086005 2 0.028
skeletal muscle tissue development GO:0007519 31 0.028
striated muscle tissue development GO:0014706 58 0.028
cardiac muscle cell contraction GO:0086003 10 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
Rat
positive regulation of signal transduction GO:0009967 175 0.027
calcium ion transmembrane transport GO:0070588 70 0.027
cardiac muscle cell development GO:0055013 16 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
Rat
tissue development GO:0009888 252 0.026
response to other organism GO:0051707 220 0.026
Rat
positive regulation of cell projection organization GO:0031346 111 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
cell projection morphogenesis GO:0048858 123 0.026
positive regulation of gene expression GO:0010628 244 0.026
single organism biosynthetic process GO:0044711 342 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
cellular response to abiotic stimulus GO:0071214 85 0.025
heterocycle catabolic process GO:0046700 167 0.025
Rat
positive regulation of nervous system development GO:0051962 178 0.025
response to nutrient GO:0007584 248 0.025
axon development GO:0061564 96 0.025
positive regulation of signaling GO:0023056 270 0.025
negative regulation of neuron differentiation GO:0045665 62 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
nucleotide metabolic process GO:0009117 279 0.024
response to ethanol GO:0045471 162 0.024
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.024
positive regulation of cell development GO:0010720 176 0.024
muscle organ development GO:0007517 50 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
reactive oxygen species metabolic process GO:0072593 37 0.024
regulation of ion transmembrane transporter activity GO:0032412 48 0.023
regulation of signal transduction GO:0009966 318 0.023
regulation of establishment of planar polarity GO:0090175 2 0.023
cardiovascular system development GO:0072358 134 0.023
regulation of neurogenesis GO:0050767 247 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
Rat
intracellular transport GO:0046907 185 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
Rat
organic acid metabolic process GO:0006082 292 0.023
cellular amine metabolic process GO:0044106 38 0.023
protein complex subunit organization GO:0071822 302 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
response to glucocorticoid GO:0051384 223 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
neuron death GO:0070997 127 0.022
female pregnancy GO:0007565 122 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
regulation of cellular localization GO:0060341 263 0.022
cell cell signaling GO:0007267 335 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
single organism intracellular transport GO:1902582 166 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of membrane potential GO:0042391 110 0.021
response to peptide hormone GO:0043434 278 0.021
Rat
response to oxidative stress GO:0006979 186 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
Rat
organic substance catabolic process GO:1901575 316 0.021
Rat
positive regulation of synaptic transmission GO:0050806 62 0.021
calcium ion transport GO:0006816 131 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
Rat
response to external biotic stimulus GO:0043207 221 0.020
Rat
positive regulation of response to stimulus GO:0048584 285 0.020
organelle organization GO:0006996 266 0.020
cellular protein localization GO:0034613 122 0.020
neuron development GO:0048666 286 0.020
calcium ion transport into cytosol GO:0060402 38 0.020
cardiocyte differentiation GO:0035051 22 0.020
cell part morphogenesis GO:0032990 123 0.020
response to camp GO:0051591 91 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of reactive oxygen species metabolic process GO:2000377 26 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
negative regulation of gene expression GO:0010629 199 0.019
cellular response to mechanical stimulus GO:0071260 48 0.019
oxoacid metabolic process GO:0043436 290 0.019
negative regulation of transporter activity GO:0032410 13 0.019
secretion by cell GO:0032940 248 0.018
cell growth GO:0016049 104 0.018
sequestering of metal ion GO:0051238 9 0.018
response to growth factor GO:0070848 189 0.018
anion transport GO:0006820 178 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
response to alkaloid GO:0043279 132 0.018
calcium mediated signaling GO:0019722 23 0.018
macromolecular complex assembly GO:0065003 273 0.018
response to reactive oxygen species GO:0000302 120 0.017
cellular catabolic process GO:0044248 295 0.017
Rat
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.017
maintenance of location GO:0051235 17 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
neuronal action potential GO:0019228 35 0.017
regulation of phagocytosis engulfment GO:0060099 4 0.017
brain development GO:0007420 247 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
cell migration GO:0016477 197 0.017
negative regulation of developmental process GO:0051093 125 0.017
response to vitamin GO:0033273 131 0.017
response to radiation GO:0009314 137 0.017
positive regulation of phosphorylation GO:0042327 177 0.016
second messenger mediated signaling GO:0019932 51 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
cardiac conduction GO:0061337 2 0.016
regulation of cell projection size GO:0032536 1 0.016
response to ketone GO:1901654 182 0.016
gliogenesis GO:0042063 93 0.016
establishment of tissue polarity GO:0007164 2 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
response to cytokine GO:0034097 215 0.016
translation GO:0006412 35 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
cellular response to external stimulus GO:0071496 118 0.016
aging GO:0007568 241 0.015
synaptic transmission GO:0007268 235 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cellular protein complex assembly GO:0043623 44 0.015
positive regulation of ion transport GO:0043270 94 0.015
cardiac cell development GO:0055006 16 0.015
response to corticosteroid GO:0031960 235 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
muscle cell development GO:0055001 26 0.015
protein transport GO:0015031 132 0.015
response to acid chemical GO:0001101 222 0.015
immune response GO:0006955 104 0.015
response to organophosphorus GO:0046683 102 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of cell death GO:0010942 184 0.015
proteolysis GO:0006508 175 0.015
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
growth GO:0040007 165 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
Rat
response to tumor necrosis factor GO:0034612 56 0.014
regulation of anatomical structure size GO:0090066 135 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.014
Rat
cellular macromolecular complex assembly GO:0034622 58 0.014
dna metabolic process GO:0006259 96 0.014
Human Rat
organic hydroxy compound metabolic process GO:1901615 115 0.014
cytokine production GO:0001816 61 0.014
regulation of smooth muscle contraction GO:0006940 29 0.014
response to electrical stimulus GO:0051602 56 0.014
protein phosphorylation GO:0006468 345 0.014
cell morphogenesis GO:0000902 142 0.013
regulation of transmembrane transport GO:0034762 122 0.013
regulation of cardiac muscle cell contraction GO:0086004 11 0.013
positive regulation of ion transmembrane transport GO:0034767 24 0.013
aromatic compound catabolic process GO:0019439 168 0.013
Rat
cellular macromolecule localization GO:0070727 122 0.013
glial cell differentiation GO:0010001 65 0.013
stress activated protein kinase signaling cascade GO:0031098 37 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
neuron projection morphogenesis GO:0048812 122 0.013
regulation of cell growth GO:0001558 85 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.013
protein complex biogenesis GO:0070271 263 0.013
response to antibiotic GO:0046677 39 0.013
progesterone biosynthetic process GO:0006701 3 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
Rat
regulation of cellular response to stress GO:0080135 49 0.013
actin filament based process GO:0030029 86 0.013
neuron fate commitment GO:0048663 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of response to stress GO:0080134 126 0.012
single organism catabolic process GO:0044712 283 0.012
Rat
cellular glucan metabolic process GO:0006073 23 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
microtubule cytoskeleton organization GO:0000226 25 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.012
cytoplasmic transport GO:0016482 115 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cellular response to metal ion GO:0071248 55 0.012
smooth muscle cell migration GO:0014909 36 0.012
cellular response to camp GO:0071320 26 0.012
response to mineralocorticoid GO:0051385 49 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to corticosterone GO:0051412 40 0.012
regulation of catalytic activity GO:0050790 304 0.012
gland development GO:0048732 155 0.012
response to monosaccharide GO:0034284 159 0.012
cellular response to inorganic substance GO:0071241 65 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
regulation of immune system process GO:0002682 123 0.012
membrane organization GO:0061024 94 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cardiac myofibril assembly GO:0055003 1 0.012
positive regulation of potassium ion transport GO:0043268 13 0.012
regulation of actin filament based process GO:0032970 42 0.012
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of phosphorylation GO:0042325 248 0.011
regulation of intracellular transport GO:0032386 65 0.011
leukocyte migration GO:0050900 38 0.011
reproductive structure development GO:0048608 128 0.011
purine containing compound metabolic process GO:0072521 253 0.011
nucleoside metabolic process GO:0009116 179 0.011
Rat
regulation of cellular component biogenesis GO:0044087 86 0.011
vesicle mediated transport GO:0016192 181 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
protein polymerization GO:0051258 22 0.011
wound healing GO:0042060 122 0.011
divalent metal ion transport GO:0070838 132 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
Rat
bile acid biosynthetic process GO:0006699 3 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
cellular component morphogenesis GO:0032989 155 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
reproductive system development GO:0061458 128 0.011
lipid storage GO:0019915 1 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
regulation of protein localization GO:0032880 81 0.011
regulation of cation channel activity GO:2001257 23 0.011
response to ionizing radiation GO:0010212 59 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 17 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
neurological system process GO:0050877 219 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
regulation of organelle organization GO:0033043 80 0.010
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.010
sexual reproduction GO:0019953 148 0.010
regulation of hydrolase activity GO:0051336 143 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of cytokine production GO:0001817 56 0.010
microtubule based process GO:0007017 36 0.010
macromolecule catabolic process GO:0009057 58 0.010
negative regulation of nervous system development GO:0051961 79 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
response to activity GO:0014823 73 0.010
macromolecule localization GO:0033036 252 0.010

Apobec2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.261
musculoskeletal system disease DOID:17 0 0.261
muscular disease DOID:0080000 0 0.100
muscle tissue disease DOID:66 0 0.100
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.028
myopathy DOID:423 0 0.025
muscular dystrophy DOID:9884 0 0.015