Rattus norvegicus

220 known processes

Arhgap4

Rho GTPase activating protein 4

Arhgap4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lymphocyte activation GO:0046649 43 0.358
regulation of phosphate metabolic process GO:0019220 349 0.304
leukocyte activation GO:0045321 76 0.299
positive regulation of cellular component movement GO:0051272 102 0.270
nucleic acid templated transcription GO:0097659 379 0.252
positive regulation of multicellular organismal process GO:0051240 387 0.237
defense response GO:0006952 194 0.228
organophosphate metabolic process GO:0019637 370 0.217
regulation of immune response GO:0050776 55 0.203
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.199
positive regulation of cell proliferation GO:0008284 249 0.193
positive regulation of developmental process GO:0051094 283 0.192
positive regulation of cell death GO:0010942 184 0.178
cell migration GO:0016477 197 0.178
regulation of response to external stimulus GO:0032101 106 0.177
positive regulation of programmed cell death GO:0043068 157 0.176
organic substance catabolic process GO:1901575 316 0.167
regulation of cellular component movement GO:0051270 150 0.167
regulation of locomotion GO:0040012 148 0.166
protein phosphorylation GO:0006468 345 0.160
regulation of catalytic activity GO:0050790 304 0.156
apoptotic process GO:0006915 381 0.151
purine nucleoside triphosphate catabolic process GO:0009146 122 0.148
regulation of cell motility GO:2000145 131 0.146
regulation of apoptotic process GO:0042981 335 0.141
immune response GO:0006955 104 0.139
positive regulation of catalytic activity GO:0043085 184 0.138
positive regulation of locomotion GO:0040017 102 0.137
positive regulation of protein metabolic process GO:0051247 178 0.135
regulation of cell differentiation GO:0045595 320 0.135
rna metabolic process GO:0016070 406 0.134
regulation of cell proliferation GO:0042127 359 0.132
regulation of rna biosynthetic process GO:2001141 381 0.131
rna biosynthetic process GO:0032774 380 0.127
regulation of cytokine production GO:0001817 56 0.126
cell motility GO:0048870 202 0.125
positive regulation of cellular biosynthetic process GO:0031328 295 0.125
b cell differentiation GO:0030183 2 0.120
regulation of programmed cell death GO:0043067 341 0.119
regulation of secretion by cell GO:1903530 208 0.117
positive regulation of apoptotic process GO:0043065 154 0.116
cellular component movement GO:0006928 248 0.115
negative regulation of metabolic process GO:0009892 331 0.115
neuron differentiation GO:0030182 368 0.111
regulation of leukocyte activation GO:0002694 45 0.110
regulation of rna metabolic process GO:0051252 391 0.110
positive regulation of gene expression GO:0010628 244 0.110
single organism catabolic process GO:0044712 283 0.109
cell activation GO:0001775 97 0.109
reproductive process GO:0022414 372 0.105
regulation of cellular localization GO:0060341 263 0.104
lipid metabolic process GO:0006629 283 0.104
immune effector process GO:0002252 53 0.104
purine ribonucleotide catabolic process GO:0009154 136 0.103
ribonucleoside triphosphate catabolic process GO:0009203 122 0.103
regulation of phosphorylation GO:0042325 248 0.102
leukocyte mediated immunity GO:0002443 28 0.102
positive regulation of phosphate metabolic process GO:0045937 262 0.102
organonitrogen compound catabolic process GO:1901565 179 0.101
negative regulation of programmed cell death GO:0043069 183 0.100
regulation of phosphorus metabolic process GO:0051174 349 0.100
regulation of protein phosphorylation GO:0001932 183 0.100
t cell activation GO:0042110 29 0.100
programmed cell death GO:0012501 392 0.098
positive regulation of exocytosis GO:0045921 19 0.098
purine ribonucleoside catabolic process GO:0046130 124 0.096
regulation of signal transduction GO:0009966 318 0.094
positive regulation of molecular function GO:0044093 230 0.093
regulation of protein modification process GO:0031399 194 0.093
purine nucleoside catabolic process GO:0006152 124 0.091
regulation of neuron death GO:1901214 115 0.090
ribonucleoside triphosphate metabolic process GO:0009199 141 0.089
regulation of molecular function GO:0065009 398 0.088
signal transduction by phosphorylation GO:0023014 144 0.087
secretion by cell GO:0032940 248 0.087
intracellular transport GO:0046907 185 0.087
positive regulation of intracellular signal transduction GO:1902533 138 0.085
locomotion GO:0040011 237 0.083
neuron death GO:0070997 127 0.083
positive regulation of cell motility GO:2000147 97 0.083
cellular homeostasis GO:0019725 252 0.083
negative regulation of biosynthetic process GO:0009890 168 0.082
positive regulation of immunoglobulin production GO:0002639 4 0.080
intracellular signal transduction GO:0035556 314 0.080
nucleoside triphosphate metabolic process GO:0009141 144 0.079
regulation of protein metabolic process GO:0051246 289 0.078
immune system development GO:0002520 41 0.078
cytoskeleton organization GO:0007010 111 0.077
positive regulation of cell migration GO:0030335 96 0.077
nucleotide catabolic process GO:0009166 139 0.076
positive regulation of phosphorus metabolic process GO:0010562 262 0.075
regulation of secretion GO:0051046 224 0.075
epithelial cell differentiation GO:0030855 71 0.075
organelle organization GO:0006996 266 0.075
organophosphate catabolic process GO:0046434 148 0.075
regulation of response to stress GO:0080134 126 0.075
regulation of cell development GO:0060284 263 0.074
positive regulation of neurogenesis GO:0050769 165 0.074
cell cell signaling GO:0007267 335 0.074
cytokine production GO:0001816 61 0.073
cellular response to peptide GO:1901653 133 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.072
regulation of anatomical structure morphogenesis GO:0022603 141 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.072
negative regulation of response to stimulus GO:0048585 155 0.070
antigen receptor mediated signaling pathway GO:0050851 1 0.070
b cell mediated immunity GO:0019724 4 0.069
response to inorganic substance GO:0010035 377 0.069
mapk cascade GO:0000165 140 0.069
positive regulation of phosphorylation GO:0042327 177 0.069
regulation of nervous system development GO:0051960 264 0.068
positive regulation of cell differentiation GO:0045597 217 0.068
oxoacid metabolic process GO:0043436 290 0.067
negative regulation of cell death GO:0060548 229 0.067
tissue development GO:0009888 252 0.067
positive regulation of biosynthetic process GO:0009891 319 0.067
homeostatic process GO:0042592 331 0.066
transcription dna templated GO:0006351 377 0.065
response to wounding GO:0009611 254 0.064
inflammatory response GO:0006954 150 0.064
regulation of nucleic acid templated transcription GO:1903506 380 0.064
response to lipopolysaccharide GO:0032496 191 0.063
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.063
purine nucleoside metabolic process GO:0042278 169 0.063
positive regulation of immune system process GO:0002684 90 0.063
response to biotic stimulus GO:0009607 226 0.062
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.062
mast cell migration GO:0097531 4 0.062
nucleoside phosphate metabolic process GO:0006753 283 0.062
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.062
regulation of neuron apoptotic process GO:0043523 83 0.061
response to cytokine GO:0034097 215 0.060
cellular response to endogenous stimulus GO:0071495 377 0.060
catabolic process GO:0009056 351 0.059
mesoderm development GO:0007498 2 0.058
response to oxidative stress GO:0006979 186 0.057
positive regulation of leukocyte activation GO:0002696 30 0.057
positive regulation of cellular protein metabolic process GO:0032270 167 0.057
regulation of protein kinase activity GO:0045859 105 0.056
cellular response to lipopolysaccharide GO:0071222 55 0.056
regulation of intracellular signal transduction GO:1902531 218 0.055
taxis GO:0042330 67 0.055
regulation of cellular ketone metabolic process GO:0010565 27 0.054
aromatic compound catabolic process GO:0019439 168 0.054
response to peptide hormone GO:0043434 278 0.054
positive regulation of cell projection organization GO:0031346 111 0.054
response to external biotic stimulus GO:0043207 221 0.054
positive regulation of smooth muscle cell migration GO:0014911 27 0.053
single organism organelle organization GO:1902589 180 0.053
cellular component morphogenesis GO:0032989 155 0.052
purine ribonucleotide metabolic process GO:0009150 227 0.052
regulation of exocytosis GO:0017157 37 0.052
positive regulation of transcription dna templated GO:0045893 197 0.052
aging GO:0007568 241 0.051
cellular ketone metabolic process GO:0042180 51 0.051
positive regulation of protein phosphorylation GO:0001934 135 0.051
positive regulation of nucleic acid templated transcription GO:1903508 197 0.051
purine nucleoside triphosphate metabolic process GO:0009144 141 0.051
cell type specific apoptotic process GO:0097285 134 0.051
cellular lipid metabolic process GO:0044255 208 0.051
purine containing compound metabolic process GO:0072521 253 0.051
carbohydrate derivative catabolic process GO:1901136 147 0.050
cellular response to lipid GO:0071396 201 0.050
cellular amine metabolic process GO:0044106 38 0.050
positive regulation of transport GO:0051050 245 0.049
positive regulation of response to stimulus GO:0048584 285 0.048
regulation of neuron projection development GO:0010975 161 0.048
peptidyl tyrosine phosphorylation GO:0018108 72 0.047
cell activation involved in immune response GO:0002263 16 0.047
peptidyl tyrosine modification GO:0018212 72 0.047
cytosolic calcium ion homeostasis GO:0051480 140 0.047
regulation of smooth muscle cell proliferation GO:0048660 75 0.046
t cell receptor signaling pathway GO:0050852 1 0.046
cellular response to nitrogen compound GO:1901699 210 0.045
t cell proliferation GO:0042098 19 0.045
positive regulation of nucleotide metabolic process GO:0045981 91 0.045
response to other organism GO:0051707 220 0.045
embryonic pattern specification GO:0009880 1 0.045
purine nucleotide catabolic process GO:0006195 136 0.044
negative regulation of apoptotic process GO:0043066 181 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
cellular catabolic process GO:0044248 295 0.044
regulation of cell morphogenesis GO:0022604 77 0.043
hematopoietic or lymphoid organ development GO:0048534 36 0.043
response to bacterium GO:0009617 200 0.043
neuron apoptotic process GO:0051402 88 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.042
cellular component biogenesis GO:0044085 368 0.042
positive regulation of nervous system development GO:0051962 178 0.042
cellular calcium ion homeostasis GO:0006874 160 0.042
regulation of vesicle mediated transport GO:0060627 81 0.042
positive regulation of cell development GO:0010720 176 0.041
antigen processing and presentation GO:0019882 2 0.041
glycosyl compound catabolic process GO:1901658 126 0.041
organic acid metabolic process GO:0006082 292 0.041
regulation of immune system process GO:0002682 123 0.041
cardiovascular system development GO:0072358 134 0.041
positive regulation of rna biosynthetic process GO:1902680 197 0.041
positive regulation of signaling GO:0023056 270 0.041
regulation of leukocyte degranulation GO:0043300 6 0.041
carboxylic acid metabolic process GO:0019752 289 0.040
cellular component assembly GO:0022607 360 0.040
positive regulation of gtpase activity GO:0043547 47 0.040
divalent inorganic cation homeostasis GO:0072507 165 0.039
chemotaxis GO:0006935 66 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.039
regulation of defense response GO:0031347 68 0.039
negative regulation of cell proliferation GO:0008285 119 0.039
regulation of neurogenesis GO:0050767 247 0.039
negative regulation of immune response GO:0050777 15 0.039
calcium ion homeostasis GO:0055074 162 0.039
cytokine biosynthetic process GO:0042089 3 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.039
regulation of lymphocyte proliferation GO:0050670 26 0.039
regulation of cell activation GO:0050865 50 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
negative regulation of signaling GO:0023057 157 0.038
amine metabolic process GO:0009308 38 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
regulation of cellular component organization GO:0051128 368 0.037
sequestering of metal ion GO:0051238 9 0.037
positive regulation of rna metabolic process GO:0051254 203 0.037
cell killing GO:0001906 13 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.037
response to growth factor GO:0070848 189 0.037
glycosyl compound metabolic process GO:1901657 182 0.037
response to virus GO:0009615 17 0.037
protein complex subunit organization GO:0071822 302 0.037
organic hydroxy compound metabolic process GO:1901615 115 0.037
negative regulation of immune system process GO:0002683 39 0.037
cellular divalent inorganic cation homeostasis GO:0072503 162 0.037
purine nucleotide metabolic process GO:0006163 229 0.036
protein transport GO:0015031 132 0.036
signal release GO:0023061 145 0.036
ribonucleotide catabolic process GO:0009261 136 0.036
ribonucleoside catabolic process GO:0042454 126 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
anatomical structure formation involved in morphogenesis GO:0048646 83 0.036
response to metal ion GO:0010038 253 0.035
brain development GO:0007420 247 0.035
negative regulation of cytokine production GO:0001818 16 0.035
cellular chemical homeostasis GO:0055082 247 0.035
defense response to other organism GO:0098542 17 0.035
sequestering of calcium ion GO:0051208 8 0.035
regulation of kinase activity GO:0043549 117 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
vesicle mediated transport GO:0016192 181 0.033
nucleoside metabolic process GO:0009116 179 0.033
negative regulation of multicellular organismal process GO:0051241 203 0.033
gtp catabolic process GO:0006184 71 0.033
hormone secretion GO:0046879 115 0.033
nucleoside catabolic process GO:0009164 126 0.033
dephosphorylation GO:0016311 98 0.033
regulation of transcription dna templated GO:0006355 374 0.033
positive regulation of mapk cascade GO:0043410 92 0.033
epithelium development GO:0060429 96 0.032
chemical homeostasis GO:0048878 292 0.032
regulation of homeostatic process GO:0032844 101 0.032
positive regulation of immune response GO:0050778 42 0.032
immunoglobulin mediated immune response GO:0016064 4 0.032
circulatory system process GO:0003013 183 0.032
mononuclear cell proliferation GO:0032943 29 0.032
positive regulation of protein modification process GO:0031401 142 0.032
immune system process GO:0002376 204 0.032
cellular metal ion homeostasis GO:0006875 172 0.031
negative regulation of developmental process GO:0051093 125 0.031
lymphocyte activation involved in immune response GO:0002285 3 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
erk1 and erk2 cascade GO:0070371 48 0.031
multi organism reproductive process GO:0044703 262 0.031
guanosine containing compound catabolic process GO:1901069 71 0.031
regulation of isotype switching GO:0045191 1 0.030
regulation of immunoglobulin production GO:0002637 4 0.030
blood vessel morphogenesis GO:0048514 58 0.030
regulation of interleukin 6 production GO:0032675 12 0.030
regulation of neuron differentiation GO:0045664 208 0.030
regulation of transferase activity GO:0051338 123 0.030
eosinophil migration GO:0072677 3 0.030
response to oxygen levels GO:0070482 265 0.030
regeneration GO:0031099 163 0.030
single organism reproductive process GO:0044702 297 0.030
cell chemotaxis GO:0060326 31 0.029
muscle contraction GO:0006936 88 0.029
positive regulation of neuron differentiation GO:0045666 126 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
positive regulation of hydrolase activity GO:0051345 86 0.029
positive regulation of lymphocyte activation GO:0051251 25 0.029
ribonucleotide metabolic process GO:0009259 231 0.029
response to peptide GO:1901652 292 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
heterocycle catabolic process GO:0046700 167 0.029
purine nucleoside monophosphate catabolic process GO:0009128 55 0.028
anterior posterior pattern specification GO:0009952 1 0.028
nucleotide metabolic process GO:0009117 279 0.028
muscle cell proliferation GO:0033002 84 0.028
negative regulation of molecular function GO:0044092 133 0.028
b cell activation involved in immune response GO:0002312 1 0.028
ion homeostasis GO:0050801 212 0.028
localization of cell GO:0051674 202 0.028
leukocyte cell cell adhesion GO:0007159 4 0.028
smooth muscle cell proliferation GO:0048659 77 0.028
regulation of immune effector process GO:0002697 32 0.027
cell adhesion GO:0007155 110 0.027
exocytosis GO:0006887 60 0.027
regulation of mononuclear cell proliferation GO:0032944 26 0.027
protein autophosphorylation GO:0046777 66 0.027
lymphocyte proliferation GO:0046651 29 0.027
regulation of synaptic transmission GO:0050804 141 0.027
regulation of response to wounding GO:1903034 69 0.027
secretion GO:0046903 307 0.027
leukocyte differentiation GO:0002521 30 0.027
head development GO:0060322 247 0.027
positive regulation of cytokine production GO:0001819 42 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
hemopoiesis GO:0030097 34 0.026
regulation of b cell differentiation GO:0045577 1 0.026
nucleoside phosphate catabolic process GO:1901292 140 0.026
lymphocyte migration GO:0072676 3 0.026
hormone transport GO:0009914 121 0.026
regulation of t cell migration GO:2000404 1 0.026
alcohol metabolic process GO:0006066 77 0.026
neuron development GO:0048666 286 0.026
purine containing compound catabolic process GO:0072523 138 0.026
regulation of metal ion transport GO:0010959 118 0.025
regulated secretory pathway GO:0045055 17 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
negative regulation of nervous system development GO:0051961 79 0.025
neuron projection development GO:0031175 273 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
response to amino acid GO:0043200 75 0.025
regulation of hormone levels GO:0010817 187 0.025
macromolecule localization GO:0033036 252 0.025
peptidyl amino acid modification GO:0018193 126 0.025
hepaticobiliary system development GO:0061008 90 0.025
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.025
cell projection organization GO:0030030 302 0.025
cytokine mediated signaling pathway GO:0019221 43 0.025
cell junction organization GO:0034330 21 0.025
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.024
central nervous system development GO:0007417 311 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
positive regulation of isotype switching GO:0045830 1 0.024
response to extracellular stimulus GO:0009991 380 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
eosinophil chemotaxis GO:0048245 3 0.023
negative regulation of neuron death GO:1901215 69 0.023
negative regulation of signal transduction GO:0009968 83 0.023
metal ion transport GO:0030001 289 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
regulation of cell adhesion GO:0030155 52 0.023
liver development GO:0001889 90 0.023
regulation of alpha beta t cell activation GO:0046634 2 0.023
synaptic transmission GO:0007268 235 0.022
negative regulation of transport GO:0051051 136 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.022
stress activated mapk cascade GO:0051403 35 0.022
synaptic growth at neuromuscular junction GO:0051124 1 0.022
positive regulation of cell communication GO:0010647 271 0.022
positive regulation of nucleoside metabolic process GO:0045979 55 0.022
regulation of cell migration GO:0030334 128 0.022
angioblast cell migration GO:0035476 1 0.022
positive regulation of mononuclear cell proliferation GO:0032946 20 0.022
positive regulation of secretion GO:0051047 140 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
regulation of mapk cascade GO:0043408 116 0.022
monosaccharide metabolic process GO:0005996 61 0.021
regulation of t cell activation GO:0050863 23 0.021
regulation of regulated secretory pathway GO:1903305 7 0.021
positive regulation of ras gtpase activity GO:0032320 28 0.021
single organism intracellular transport GO:1902582 166 0.021
innate immune response GO:0045087 35 0.021
negative regulation of secretion by cell GO:1903531 72 0.021
regulation of b cell mediated immunity GO:0002712 2 0.021
response to acid chemical GO:0001101 222 0.021
salivary gland morphogenesis GO:0007435 1 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
growth GO:0040007 165 0.021
glycerolipid metabolic process GO:0046486 67 0.021
circulatory system development GO:0072359 134 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
cytoplasmic transport GO:0016482 115 0.020
regulation of leukocyte proliferation GO:0070663 26 0.020
regulation of immunoglobulin mediated immune response GO:0002889 2 0.020
reproduction GO:0000003 245 0.020
negative regulation of neutrophil apoptotic process GO:0033030 3 0.020
leukocyte proliferation GO:0070661 29 0.020
maintenance of location GO:0051235 17 0.020
regulation of cell projection organization GO:0031344 175 0.020
gland development GO:0048732 155 0.020
leukocyte activation involved in immune response GO:0002366 16 0.020
negative regulation of cell development GO:0010721 82 0.020
metal ion homeostasis GO:0055065 186 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
gamete generation GO:0007276 124 0.019
regulation of neural precursor cell proliferation GO:2000177 16 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
ras protein signal transduction GO:0007265 29 0.019
lymphocyte mediated immunity GO:0002449 14 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
gtp metabolic process GO:0046039 72 0.019
cellular carbohydrate metabolic process GO:0044262 72 0.019
cation transport GO:0006812 382 0.019
positive regulation of transferase activity GO:0051347 81 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
alpha beta t cell differentiation GO:0046632 2 0.018
positive regulation of nucleotide catabolic process GO:0030813 53 0.018
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.018
insulin like growth factor receptor signaling pathway GO:0048009 3 0.018
erythrocyte differentiation GO:0030218 1 0.018
divalent metal ion transport GO:0070838 132 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
lipid biosynthetic process GO:0008610 128 0.018
myeloid leukocyte activation GO:0002274 36 0.018
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.018
release of sequestered calcium ion into cytosol GO:0051209 25 0.018
activation of immune response GO:0002253 26 0.018
negative regulation of cell communication GO:0010648 158 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cell morphogenesis GO:0000902 142 0.018
leukocyte degranulation GO:0043299 12 0.018
regulation of synaptic plasticity GO:0048167 70 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
regulation of protein transport GO:0051223 68 0.018
positive regulation of cellular component organization GO:0051130 200 0.017
protein complex assembly GO:0006461 263 0.017
response to reactive oxygen species GO:0000302 120 0.017
insulin receptor signaling pathway GO:0008286 24 0.017
positive regulation of kinase activity GO:0033674 77 0.017
positive regulation of cell activation GO:0050867 34 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
negative regulation of innate immune response GO:0045824 4 0.017
axis specification GO:0009798 4 0.017
response to hydrogen peroxide GO:0042542 89 0.017
regulation of hydrolase activity GO:0051336 143 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
regulation of cellular response to insulin stimulus GO:1900076 16 0.017
negative regulation of luteinizing hormone secretion GO:0033685 4 0.017
organelle localization GO:0051640 55 0.017
regulation of growth GO:0040008 105 0.016
cellular response to oxidative stress GO:0034599 76 0.016
muscle system process GO:0003012 115 0.016
cellular response to stress GO:0033554 269 0.016
blood circulation GO:0008015 183 0.016
regulation of dna metabolic process GO:0051052 60 0.016
interleukin 12 production GO:0032615 3 0.016
regulation of dendrite development GO:0050773 59 0.016
memory GO:0007613 54 0.016
regulation of blood vessel endothelial cell migration GO:0043535 4 0.016
negative regulation of immune response to tumor cell GO:0002838 2 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
defense response to virus GO:0051607 9 0.016
gastrulation GO:0007369 2 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.016
single organism membrane organization GO:0044802 74 0.016
endomembrane system organization GO:0010256 48 0.015
spindle organization GO:0007051 2 0.015
positive regulation of cell adhesion GO:0045785 30 0.015
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.015
response to glucose GO:0009749 136 0.015
regulation of leukocyte differentiation GO:1902105 20 0.015
regulation of gtpase activity GO:0043087 57 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.015
proteolysis GO:0006508 175 0.015
positive regulation of gtp catabolic process GO:0033126 48 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
peptide secretion GO:0002790 86 0.015
lysosome localization GO:0032418 10 0.015
reproductive system development GO:0061458 128 0.015
negative regulation of homeostatic process GO:0032845 47 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of behavior GO:0050795 61 0.015
t helper 1 type immune response GO:0042088 1 0.015
platelet aggregation GO:0070527 4 0.015
regulation of erk1 and erk2 cascade GO:0070372 41 0.015
lymphocyte homeostasis GO:0002260 2 0.015
positive regulation of leukocyte proliferation GO:0070665 20 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.015

Arhgap4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
musculoskeletal system disease DOID:17 0 0.068
connective tissue disease DOID:65 0 0.047
retinal disease DOID:5679 0 0.018
retinal degeneration DOID:8466 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
eye disease DOID:5614 0 0.018