Rattus norvegicus

0 known processes

Asb12

ankyrin repeat and SOCS box-containing 12

(Aliases: MGC125221)

Asb12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
divalent inorganic cation homeostasis GO:0072507 165 0.254
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.131
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.115
neuron projection development GO:0031175 273 0.113
cellular calcium ion homeostasis GO:0006874 160 0.113
calcium ion homeostasis GO:0055074 162 0.105
regulation of ion transport GO:0043269 245 0.104
cellular divalent inorganic cation homeostasis GO:0072503 162 0.092
regulation of system process GO:0044057 208 0.092
regulation of signal transduction GO:0009966 318 0.088
neuron development GO:0048666 286 0.086
positive regulation of cell proliferation GO:0008284 249 0.086
response to biotic stimulus GO:0009607 226 0.080
cell projection organization GO:0030030 302 0.073
positive regulation of multicellular organismal process GO:0051240 387 0.071
cellular metal ion homeostasis GO:0006875 172 0.069
positive regulation of developmental process GO:0051094 283 0.066
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.065
metal ion homeostasis GO:0055065 186 0.064
chemical homeostasis GO:0048878 292 0.061
anion transport GO:0006820 178 0.060
regulation of catalytic activity GO:0050790 304 0.059
cellular ion homeostasis GO:0006873 184 0.058
regulation of intracellular signal transduction GO:1902531 218 0.058
cellular component movement GO:0006928 248 0.057
muscle system process GO:0003012 115 0.056
localization of cell GO:0051674 202 0.055
regulation of neuron projection development GO:0010975 161 0.053
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.053
tissue development GO:0009888 252 0.053
cellular chemical homeostasis GO:0055082 247 0.051
cellular component assembly GO:0022607 360 0.050
homeostatic process GO:0042592 331 0.049
cellular cation homeostasis GO:0030003 180 0.049
blood circulation GO:0008015 183 0.048
central nervous system development GO:0007417 311 0.048
regulation of molecular function GO:0065009 398 0.047
response to mechanical stimulus GO:0009612 134 0.047
response to decreased oxygen levels GO:0036293 237 0.047
cellular component biogenesis GO:0044085 368 0.046
negative regulation of metabolic process GO:0009892 331 0.045
neuron differentiation GO:0030182 368 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
regulation of cell differentiation GO:0045595 320 0.045
ion homeostasis GO:0050801 212 0.044
cation transport GO:0006812 382 0.044
regulation of cell proliferation GO:0042127 359 0.042
calcium ion transport into cytosol GO:0060402 38 0.040
divalent inorganic cation transport GO:0072511 134 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.039
cellular homeostasis GO:0019725 252 0.038
regulation of multicellular organismal development GO:2000026 376 0.037
inorganic ion transmembrane transport GO:0098660 229 0.036
protein oligomerization GO:0051259 191 0.035
positive regulation of response to stimulus GO:0048584 285 0.035
cytoplasmic transport GO:0016482 115 0.035
cellular response to stress GO:0033554 269 0.035
protein complex subunit organization GO:0071822 302 0.034
regulation of nervous system development GO:0051960 264 0.034
intracellular transport GO:0046907 185 0.034
response to hypoxia GO:0001666 231 0.033
cellular response to steroid hormone stimulus GO:0071383 93 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
regulation of muscle contraction GO:0006937 53 0.032
regulation of muscle system process GO:0090257 79 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of locomotion GO:0040012 148 0.031
regulation of cell development GO:0060284 263 0.031
metal ion transport GO:0030001 289 0.031
cation homeostasis GO:0055080 195 0.031
response to alkaloid GO:0043279 132 0.030
circulatory system process GO:0003013 183 0.030
limb morphogenesis GO:0035108 4 0.029
multi multicellular organism process GO:0044706 138 0.029
head development GO:0060322 247 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
cytosolic calcium ion transport GO:0060401 39 0.029
multicellular organism reproduction GO:0032504 233 0.029
regulation of transcription dna templated GO:0006355 374 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
positive regulation of ion transport GO:0043270 94 0.028
regulation of rna metabolic process GO:0051252 391 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
regulation of cellular component organization GO:0051128 368 0.027
protein complex assembly GO:0006461 263 0.026
divalent metal ion transport GO:0070838 132 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
circadian rhythm GO:0007623 88 0.026
sequestering of metal ion GO:0051238 9 0.026
sequestering of calcium ion GO:0051208 8 0.026
response to corticosteroid GO:0031960 235 0.025
positive regulation of transport GO:0051050 245 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
rna biosynthetic process GO:0032774 380 0.025
defense response GO:0006952 194 0.025
gamete generation GO:0007276 124 0.025
reproduction GO:0000003 245 0.025
nucleic acid templated transcription GO:0097659 379 0.024
heart morphogenesis GO:0003007 3 0.024
behavior GO:0007610 205 0.024
organic substance catabolic process GO:1901575 316 0.024
receptor metabolic process GO:0043112 18 0.024
rna metabolic process GO:0016070 406 0.024
positive regulation of cell development GO:0010720 176 0.024
cardiac chamber development GO:0003205 1 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
regulation of cellular component movement GO:0051270 150 0.023
maintenance of location GO:0051235 17 0.023
regulation of neurogenesis GO:0050767 247 0.023
transcription dna templated GO:0006351 377 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cardiac ventricle development GO:0003231 1 0.023
regulation of neuron differentiation GO:0045664 208 0.023
regulation of phosphorylation GO:0042325 248 0.023
positive regulation of cell projection organization GO:0031346 111 0.022
macromolecular complex assembly GO:0065003 273 0.022
embryonic appendage morphogenesis GO:0035113 4 0.022
proteolysis GO:0006508 175 0.022
appendage morphogenesis GO:0035107 4 0.022
cell growth GO:0016049 104 0.022
regulation of metal ion transport GO:0010959 118 0.022
ribonucleotide biosynthetic process GO:0009260 85 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
reproductive system development GO:0061458 128 0.021
cellular component morphogenesis GO:0032989 155 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
organelle organization GO:0006996 266 0.021
ras protein signal transduction GO:0007265 29 0.021
multi organism reproductive process GO:0044703 262 0.021
regulation of epithelial cell proliferation GO:0050678 49 0.021
reactive nitrogen species metabolic process GO:2001057 1 0.021
protein phosphorylation GO:0006468 345 0.021
tissue morphogenesis GO:0048729 22 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
negative regulation of gene expression GO:0010629 199 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
negative regulation of signaling GO:0023057 157 0.020
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.019
reproductive process GO:0022414 372 0.019
response to oxygen levels GO:0070482 265 0.019
nitrogen compound transport GO:0071705 229 0.019
muscle tissue morphogenesis GO:0060415 1 0.019
cellular catabolic process GO:0044248 295 0.019
response to peptide GO:1901652 292 0.019
response to lipopolysaccharide GO:0032496 191 0.019
regulation of blood vessel size GO:0050880 89 0.019
cell morphogenesis GO:0000902 142 0.019
heart contraction GO:0060047 57 0.018
regulation of protein metabolic process GO:0051246 289 0.018
regulation of response to stress GO:0080134 126 0.018
single organism reproductive process GO:0044702 297 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of transport GO:0051051 136 0.018
negative regulation of cell communication GO:0010648 158 0.018
brain development GO:0007420 247 0.018
striated muscle contraction GO:0006941 44 0.017
ion transmembrane transport GO:0034220 365 0.017
axon development GO:0061564 96 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.017
regulation of establishment of planar polarity GO:0090175 2 0.017
catabolic process GO:0009056 351 0.017
prostate gland epithelium morphogenesis GO:0060740 2 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
endoplasmic reticulum to cytosol transport GO:1903513 4 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
regulation of membrane repolarization GO:0060306 1 0.016
reproductive structure development GO:0048608 128 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
response to carbohydrate GO:0009743 183 0.016
growth GO:0040007 165 0.016
regulation of calcium ion transport GO:0051924 77 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
axis specification GO:0009798 4 0.016
response to ethanol GO:0045471 162 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
carboxylic acid transport GO:0046942 115 0.015
response to metal ion GO:0010038 253 0.015
regulation of cell projection organization GO:0031344 175 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
response to nicotine GO:0035094 51 0.015
single organism organelle organization GO:1902589 180 0.015
embryonic limb morphogenesis GO:0030326 4 0.015
regulation of mapk cascade GO:0043408 116 0.015
locomotion GO:0040011 237 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
regulation of hydrolase activity GO:0051336 143 0.015
response to inorganic substance GO:0010035 377 0.014
muscle structure development GO:0061061 87 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
response to ketone GO:1901654 182 0.014
response to peptide hormone GO:0043434 278 0.014
purine containing compound metabolic process GO:0072521 253 0.014
release of sequestered calcium ion into cytosol GO:0051209 25 0.014
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.014
receptor mediated endocytosis GO:0006898 42 0.014
vascular process in circulatory system GO:0003018 96 0.014
protein complex biogenesis GO:0070271 263 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
secretion GO:0046903 307 0.014
programmed cell death GO:0012501 392 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
organic acid transport GO:0015849 116 0.014
organ morphogenesis GO:0009887 75 0.014
regulation of intracellular transport GO:0032386 65 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
embryonic hindlimb morphogenesis GO:0035116 2 0.014
regulation of cell motility GO:2000145 131 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
regulation of cardiac muscle contraction GO:0055117 17 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.013
epithelial cell proliferation GO:0050673 54 0.013
cellular response to lipopolysaccharide GO:0071222 55 0.013
gonad development GO:0008406 104 0.013
sensory perception of pain GO:0019233 73 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
negative regulation of signal transduction GO:0009968 83 0.013
intracellular signal transduction GO:0035556 314 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cellular amine metabolic process GO:0044106 38 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
positive regulation of molecular function GO:0044093 230 0.013
single organism intracellular transport GO:1902582 166 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
nerve development GO:0021675 11 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of nervous system development GO:0051962 178 0.013
neurological system process GO:0050877 219 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of blood circulation GO:1903522 110 0.013
positive regulation of cardiac muscle contraction GO:0060452 4 0.013
muscle contraction GO:0006936 88 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
rhythmic process GO:0048511 156 0.013
aging GO:0007568 241 0.012
response to activity GO:0014823 73 0.012
response to cytokine GO:0034097 215 0.012
positive regulation of gene expression GO:0010628 244 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
heart process GO:0003015 57 0.012
muscle organ morphogenesis GO:0048644 1 0.012
developmental process involved in reproduction GO:0003006 159 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
oxidation reduction process GO:0055114 304 0.012
positive regulation of signaling GO:0023056 270 0.012
calcium ion transport GO:0006816 131 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
response to acid chemical GO:0001101 222 0.012
positive regulation of signal transduction GO:0009967 175 0.012
negative regulation of cell death GO:0060548 229 0.012
response to wounding GO:0009611 254 0.012
transformation of host cell by virus GO:0019087 4 0.012
response to gonadotropin GO:0034698 34 0.012
response to extracellular stimulus GO:0009991 380 0.012
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.012
regulation of cellular localization GO:0060341 263 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
regulation of ras protein signal transduction GO:0046578 45 0.012
response to estradiol GO:0032355 164 0.012
regulation of secretion GO:0051046 224 0.011
organic anion transport GO:0015711 132 0.011
regulation of catabolic process GO:0009894 113 0.011
response to axon injury GO:0048678 59 0.011
sensory organ development GO:0007423 74 0.011
development of primary sexual characteristics GO:0045137 107 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
eye morphogenesis GO:0048592 4 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
synaptic transmission GO:0007268 235 0.011
anterior posterior pattern specification GO:0009952 1 0.011
regulation of catecholamine secretion GO:0050433 32 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
regulation of ion homeostasis GO:2000021 63 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
regulation of protein modification process GO:0031399 194 0.011
cellular response to fluid shear stress GO:0071498 4 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
regeneration GO:0031099 163 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
gliogenesis GO:0042063 93 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
response to oxidative stress GO:0006979 186 0.011
cellular response to iron iii ion GO:0071283 3 0.011
sexual reproduction GO:0019953 148 0.011
response to reactive oxygen species GO:0000302 120 0.011
sex differentiation GO:0007548 113 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
negative regulation of innate immune response GO:0045824 4 0.010
regulation of programmed cell death GO:0043067 341 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
regulation of cell size GO:0008361 37 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
cell adhesion GO:0007155 110 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
lipid localization GO:0010876 62 0.010
cellular response to metal ion GO:0071248 55 0.010

Asb12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.054
inherited metabolic disorder DOID:655 0 0.028
musculoskeletal system disease DOID:17 0 0.021
disease of anatomical entity DOID:7 0 0.021
muscular disease DOID:0080000 0 0.019
muscle tissue disease DOID:66 0 0.019
dilated cardiomyopathy DOID:12930 0 0.014
cardiovascular system disease DOID:1287 0 0.014
heart disease DOID:114 0 0.014
myopathy DOID:423 0 0.014
intrinsic cardiomyopathy DOID:0060036 0 0.014
cardiomyopathy DOID:0050700 0 0.014