Rattus norvegicus

0 known processes

Aspn

asporin

Aspn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
kidney development GO:0001822 67 0.364
Rat
anatomical structure morphogenesis GO:0009653 298 0.319
Mouse
extracellular matrix organization GO:0030198 13 0.256
aging GO:0007568 241 0.210
Rat
cellular component biogenesis GO:0044085 368 0.154
tissue development GO:0009888 252 0.150
Human Mouse Rat
protein complex subunit organization GO:0071822 302 0.147
intracellular signal transduction GO:0035556 314 0.146
extracellular structure organization GO:0043062 13 0.129
protein complex assembly GO:0006461 263 0.128
response to extracellular stimulus GO:0009991 380 0.126
cellular response to endogenous stimulus GO:0071495 377 0.121
Human Mouse
odontogenesis GO:0042476 32 0.119
Mouse
regulation of rna metabolic process GO:0051252 391 0.114
protein phosphorylation GO:0006468 345 0.113
response to corticosteroid GO:0031960 235 0.107
macromolecule localization GO:0033036 252 0.107
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.106
oxoacid metabolic process GO:0043436 290 0.104
response to estrogen GO:0043627 232 0.101
transcription dna templated GO:0006351 377 0.096
regulation of phosphorylation GO:0042325 248 0.095
protein complex biogenesis GO:0070271 263 0.095
single organism reproductive process GO:0044702 297 0.092
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.089
positive regulation of rna biosynthetic process GO:1902680 197 0.088
regulation of rna biosynthetic process GO:2001141 381 0.087
response to peptide GO:1901652 292 0.086
organic acid metabolic process GO:0006082 292 0.083
muscle cell proliferation GO:0033002 84 0.082
cellular response to organonitrogen compound GO:0071417 197 0.082
response to nutrient GO:0007584 248 0.078
protein transport GO:0015031 132 0.076
macromolecular complex subunit organization GO:0043933 339 0.075
response to alkaloid GO:0043279 132 0.072
reproductive process GO:0022414 372 0.070
Rat
regulation of phosphate metabolic process GO:0019220 349 0.069
eye morphogenesis GO:0048592 4 0.068
tissue remodeling GO:0048771 40 0.068
Rat
cation homeostasis GO:0055080 195 0.068
cellular response to peptide GO:1901653 133 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
protein homooligomerization GO:0051260 91 0.067
cellular ion homeostasis GO:0006873 184 0.066
extracellular fibril organization GO:0043206 1 0.066
blood circulation GO:0008015 183 0.065
growth GO:0040007 165 0.062
response to oxygen levels GO:0070482 265 0.062
response to decreased oxygen levels GO:0036293 237 0.061
wound healing GO:0042060 122 0.061
Rat
rna metabolic process GO:0016070 406 0.060
regulation of secretion GO:0051046 224 0.059
regulation of phosphorus metabolic process GO:0051174 349 0.058
regulation of apoptotic process GO:0042981 335 0.058
response to inorganic substance GO:0010035 377 0.058
cellular cation homeostasis GO:0030003 180 0.058
positive regulation of biosynthetic process GO:0009891 319 0.057
reproduction GO:0000003 245 0.056
blood vessel development GO:0001568 69 0.056
response to nutrient levels GO:0031667 370 0.054
regulation of nucleic acid templated transcription GO:1903506 380 0.054
cellular response to oxygen containing compound GO:1901701 386 0.054
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
rna biosynthetic process GO:0032774 380 0.052
cellular component assembly GO:0022607 360 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.051
cellular response to growth factor stimulus GO:0071363 162 0.050
Human Mouse
response to acid chemical GO:0001101 222 0.050
vasculature development GO:0001944 70 0.048
cardiovascular system development GO:0072358 134 0.048
macromolecular complex assembly GO:0065003 273 0.048
nucleic acid templated transcription GO:0097659 379 0.048
regulation of cell proliferation GO:0042127 359 0.047
response to mechanical stimulus GO:0009612 134 0.046
Rat
cellular response to organic cyclic compound GO:0071407 202 0.045
cellular metal ion homeostasis GO:0006875 172 0.045
cellular response to cytokine stimulus GO:0071345 127 0.045
positive regulation of phosphate metabolic process GO:0045937 262 0.045
response to growth factor GO:0070848 189 0.044
Human Mouse
regulation of cellular localization GO:0060341 263 0.044
secretion GO:0046903 307 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
growth plate cartilage development GO:0003417 2 0.043
response to cytokine GO:0034097 215 0.042
homeostatic process GO:0042592 331 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
Mouse
organ morphogenesis GO:0009887 75 0.042
Mouse
reproductive structure development GO:0048608 128 0.042
Rat
developmental growth GO:0048589 100 0.041
connective tissue development GO:0061448 33 0.041
response to tumor necrosis factor GO:0034612 56 0.041
positive regulation of protein phosphorylation GO:0001934 135 0.041
cellular homeostasis GO:0019725 252 0.041
regulation of molecular function GO:0065009 398 0.040
positive regulation of protein modification process GO:0031401 142 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
response to wounding GO:0009611 254 0.039
Rat
chemical homeostasis GO:0048878 292 0.038
response to hypoxia GO:0001666 231 0.038
brain development GO:0007420 247 0.038
positive regulation of cell death GO:0010942 184 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.037
response to vitamin e GO:0033197 24 0.037
divalent inorganic cation homeostasis GO:0072507 165 0.037
developmental process involved in reproduction GO:0003006 159 0.036
Rat
cartilage development GO:0051216 22 0.036
negative regulation of cell death GO:0060548 229 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
camera type eye morphogenesis GO:0048593 2 0.035
response to estradiol GO:0032355 164 0.035
circulatory system process GO:0003013 183 0.034
rhythmic process GO:0048511 156 0.034
regulation of protein metabolic process GO:0051246 289 0.034
single organism biosynthetic process GO:0044711 342 0.033
response to heat GO:0009408 60 0.033
cellular ketone metabolic process GO:0042180 51 0.033
positive regulation of gene expression GO:0010628 244 0.032
establishment of protein localization GO:0045184 141 0.032
circulatory system development GO:0072359 134 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
positive regulation of rna metabolic process GO:0051254 203 0.032
regulation of signal transduction GO:0009966 318 0.032
Human Mouse
positive regulation of cellular component organization GO:0051130 200 0.031
protein localization GO:0008104 191 0.031
regulation of cellular component organization GO:0051128 368 0.031
ion homeostasis GO:0050801 212 0.031
cellular sodium ion homeostasis GO:0006883 4 0.031
regulation of transferase activity GO:0051338 123 0.031
negative regulation of phosphorus metabolic process GO:0010563 80 0.031
positive regulation of molecular function GO:0044093 230 0.030
regulation of smooth muscle cell proliferation GO:0048660 75 0.030
cellular response to lipid GO:0071396 201 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
artery development GO:0060840 3 0.030
central nervous system development GO:0007417 311 0.029
regulation of protein modification process GO:0031399 194 0.029
response to vitamin GO:0033273 131 0.029
regulation of catalytic activity GO:0050790 304 0.029
positive regulation of signaling GO:0023056 270 0.029
response to peptide hormone GO:0043434 278 0.029
response to metal ion GO:0010038 253 0.029
cellular chemical homeostasis GO:0055082 247 0.029
aorta development GO:0035904 2 0.028
development of primary female sexual characteristics GO:0046545 56 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
cellular amine metabolic process GO:0044106 38 0.027
renal system development GO:0072001 67 0.027
Rat
development of primary sexual characteristics GO:0045137 107 0.027
oxidation reduction process GO:0055114 304 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
urogenital system development GO:0001655 78 0.027
Rat
positive regulation of transport GO:0051050 245 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
positive regulation of developmental process GO:0051094 283 0.026
protein oligomerization GO:0051259 191 0.026
vesicle mediated transport GO:0016192 181 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
multicellular organism reproduction GO:0032504 233 0.026
intracellular transport GO:0046907 185 0.025
carbohydrate metabolic process GO:0005975 130 0.025
response to biotic stimulus GO:0009607 226 0.025
Rat
carboxylic acid metabolic process GO:0019752 289 0.025
skeletal system development GO:0001501 41 0.024
positive regulation of signal transduction GO:0009967 175 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
cellular response to stress GO:0033554 269 0.024
secretion by cell GO:0032940 248 0.024
blood vessel morphogenesis GO:0048514 58 0.024
response to interleukin 1 GO:0070555 55 0.024
cellular component movement GO:0006928 248 0.024
smooth muscle cell proliferation GO:0048659 77 0.023
regulation of kinase activity GO:0043549 117 0.023
regulation of homeostatic process GO:0032844 101 0.023
skeletal muscle organ development GO:0060538 33 0.023
Rat
regulation of secretion by cell GO:1903530 208 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
regulation of transcription dna templated GO:0006355 374 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
muscle system process GO:0003012 115 0.022
cellular response to acid chemical GO:0071229 75 0.022
negative regulation of molecular function GO:0044092 133 0.022
epithelium development GO:0060429 96 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
nucleotide metabolic process GO:0009117 279 0.022
cellular amino acid metabolic process GO:0006520 107 0.021
regulation of nervous system development GO:0051960 264 0.021
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.021
neuron apoptotic process GO:0051402 88 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.021
Human Mouse
endochondral bone growth GO:0003416 3 0.021
cellular response to vitamin e GO:0071306 3 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
organelle organization GO:0006996 266 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
response to anoxia GO:0034059 4 0.021
sequestering of metal ion GO:0051238 9 0.021
regulation of cell development GO:0060284 263 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
response to oxidative stress GO:0006979 186 0.021
response to temperature stimulus GO:0009266 94 0.021
positive regulation of cell communication GO:0010647 271 0.021
regulation of cellular component movement GO:0051270 150 0.020
sex differentiation GO:0007548 113 0.020
regulation of cell differentiation GO:0045595 320 0.020
positive regulation of cardiac muscle contraction GO:0060452 4 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
multi organism reproductive process GO:0044703 262 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
single organism intracellular transport GO:1902582 166 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regeneration GO:0031099 163 0.019
regulation of neuron apoptotic process GO:0043523 83 0.019
ras protein signal transduction GO:0007265 29 0.018
positive regulation of secretion GO:0051047 140 0.018
neuron death GO:0070997 127 0.018
cation transmembrane transport GO:0098655 263 0.018
sequestering of calcium ion GO:0051208 8 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
female gonad development GO:0008585 53 0.018
positive regulation of cellular component biogenesis GO:0044089 55 0.018
single organism organelle organization GO:1902589 180 0.018
multi multicellular organism process GO:0044706 138 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
negative regulation of cell proliferation GO:0008285 119 0.017
neuron differentiation GO:0030182 368 0.017
gastrulation GO:0007369 2 0.017
response to lipopolysaccharide GO:0032496 191 0.017
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.017
mapk cascade GO:0000165 140 0.017
amine metabolic process GO:0009308 38 0.017
metal ion homeostasis GO:0055065 186 0.017
gonad development GO:0008406 104 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
muscle structure development GO:0061061 87 0.017
Rat
apoptotic process GO:0006915 381 0.016
endochondral bone morphogenesis GO:0060350 7 0.016
female sex differentiation GO:0046660 59 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.016
head development GO:0060322 247 0.016
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.016
regulation of heart contraction GO:0008016 48 0.016
regulation of blood pressure GO:0008217 83 0.016
reproductive system development GO:0061458 128 0.016
Rat
organ regeneration GO:0031100 101 0.015
response to fatty acid GO:0070542 65 0.015
cellular protein localization GO:0034613 122 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
response to glucose GO:0009749 136 0.015
regulation of programmed cell death GO:0043067 341 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
skeletal muscle tissue development GO:0007519 31 0.015
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
regulation of response to external stimulus GO:0032101 106 0.015
response to transforming growth factor beta GO:0071559 46 0.015
Human Mouse
regulation of ossification GO:0030278 32 0.015
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
protein heterooligomerization GO:0051291 89 0.015
skin morphogenesis GO:0043589 2 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
carbohydrate biosynthetic process GO:0016051 42 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
negative regulation of neuron death GO:1901215 69 0.014
spermatogenesis GO:0007283 99 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
locomotion GO:0040011 237 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
cation transport GO:0006812 382 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
programmed cell death GO:0012501 392 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.014
Human Mouse
neuron development GO:0048666 286 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
cell motility GO:0048870 202 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
organophosphate metabolic process GO:0019637 370 0.014
tube development GO:0035295 89 0.014
calcium ion homeostasis GO:0055074 162 0.014
neurological system process GO:0050877 219 0.014
negative regulation of metabolic process GO:0009892 331 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of odontogenesis of dentin containing tooth GO:0042487 2 0.014
response to molecule of bacterial origin GO:0002237 194 0.013
Rat
positive regulation of secretion by cell GO:1903532 128 0.013
maintenance of location GO:0051235 17 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
metal ion transport GO:0030001 289 0.013
response to dexamethasone GO:0071548 49 0.013
positive regulation of ion transport GO:0043270 94 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of neuron death GO:1901214 115 0.013
cell projection organization GO:0030030 302 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.013
response to fibroblast growth factor GO:0071774 29 0.013
rho protein signal transduction GO:0007266 11 0.013
ion transmembrane transport GO:0034220 365 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
Human Mouse
regulation of protein kinase activity GO:0045859 105 0.013
palate development GO:0060021 2 0.012
embryonic skeletal system development GO:0048706 3 0.012
single organism cellular localization GO:1902580 102 0.012
nucleoside metabolic process GO:0009116 179 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of neurogenesis GO:0050767 247 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.012
organ growth GO:0035265 24 0.012
purine containing compound metabolic process GO:0072521 253 0.012
male gamete generation GO:0048232 99 0.012
bmp signaling pathway GO:0030509 4 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
Mouse
biomineral tissue development GO:0031214 12 0.012
Human Mouse
response to hexose GO:0009746 144 0.012
peptidyl amino acid modification GO:0018193 126 0.012
cellular response to fluoride GO:1902618 1 0.012
small molecule biosynthetic process GO:0044283 124 0.012
response to glucocorticoid GO:0051384 223 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
feeding behavior GO:0007631 53 0.012
ovulation cycle GO:0042698 67 0.012
heart contraction GO:0060047 57 0.012
positive regulation of cell development GO:0010720 176 0.012
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
catabolic process GO:0009056 351 0.011
cardiac chamber development GO:0003205 1 0.011
axis elongation GO:0003401 2 0.011
cardiac muscle contraction GO:0060048 27 0.011
regulation of organelle organization GO:0033043 80 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
cellular macromolecule localization GO:0070727 122 0.011
formation of primary germ layer GO:0001704 1 0.011
male gonad development GO:0008584 59 0.011
heart morphogenesis GO:0003007 3 0.011
protein localization to organelle GO:0033365 57 0.011
gamete generation GO:0007276 124 0.011
regulation of system process GO:0044057 208 0.011
aromatic compound catabolic process GO:0019439 168 0.011
neuron projection development GO:0031175 273 0.011
embryonic pattern specification GO:0009880 1 0.011
striated muscle tissue development GO:0014706 58 0.011
Rat
developmental growth involved in morphogenesis GO:0060560 33 0.011
regulation of cell projection organization GO:0031344 175 0.011
cytoskeleton organization GO:0007010 111 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
signal release GO:0023061 145 0.011
positive regulation of bone mineralization GO:0030501 4 0.011
cellular response to external stimulus GO:0071496 118 0.011
taxis GO:0042330 67 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
cytoplasmic transport GO:0016482 115 0.010
negative regulation of signaling GO:0023057 157 0.010
Human Mouse
heterocycle catabolic process GO:0046700 167 0.010
sensory perception GO:0007600 101 0.010
response to hydrogen peroxide GO:0042542 89 0.010
cardiac ventricle development GO:0003231 1 0.010
positive regulation of nervous system development GO:0051962 178 0.010
ossification GO:0001503 70 0.010
Human
ribonucleoside metabolic process GO:0009119 174 0.010
response to monosaccharide GO:0034284 159 0.010
negative regulation of transport GO:0051051 136 0.010
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.010
regulation of ion transport GO:0043269 245 0.010
regulation of blood circulation GO:1903522 110 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
Human Mouse
inflammatory response GO:0006954 150 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
cellular lipid metabolic process GO:0044255 208 0.010
regulation of glucose transport GO:0010827 18 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010

Aspn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.116
cardiovascular system disease DOID:1287 0 0.116
musculoskeletal system disease DOID:17 0 0.049
muscular disease DOID:0080000 0 0.031
muscle tissue disease DOID:66 0 0.031
nervous system disease DOID:863 0 0.026
artery disease DOID:0050828 0 0.020
vascular disease DOID:178 0 0.020
disease of metabolism DOID:0014667 0 0.016
urinary system disease DOID:18 0 0.013
connective tissue disease DOID:65 0 0.013
hypertension DOID:10763 0 0.012
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010