Rattus norvegicus

125 known processes

Atp1a4

ATPase, Na+/K+ transporting, alpha 4 polypeptide

(Aliases: MGC93426)

Atp1a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.291
regulation of rna metabolic process GO:0051252 391 0.269
cell cell signaling GO:0007267 335 0.200
positive regulation of biosynthetic process GO:0009891 319 0.158
regulation of secretion GO:0051046 224 0.141
nucleic acid templated transcription GO:0097659 379 0.120
cation transport GO:0006812 382 0.115
regulation of rna biosynthetic process GO:2001141 381 0.113
organonitrogen compound biosynthetic process GO:1901566 167 0.100
cyclic purine nucleotide metabolic process GO:0052652 62 0.099
positive regulation of transport GO:0051050 245 0.099
rna biosynthetic process GO:0032774 380 0.098
positive regulation of signaling GO:0023056 270 0.096
positive regulation of apoptotic process GO:0043065 154 0.092
regulation of secretion by cell GO:1903530 208 0.088
intracellular signal transduction GO:0035556 314 0.087
response to external biotic stimulus GO:0043207 221 0.086
brain development GO:0007420 247 0.086
carbohydrate derivative biosynthetic process GO:1901137 124 0.084
ribose phosphate biosynthetic process GO:0046390 87 0.083
muscle contraction GO:0006936 88 0.083
Rat
purine nucleotide biosynthetic process GO:0006164 83 0.082
positive regulation of cellular biosynthetic process GO:0031328 295 0.080
purine containing compound metabolic process GO:0072521 253 0.080
transcription dna templated GO:0006351 377 0.079
purine containing compound biosynthetic process GO:0072522 85 0.078
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.076
cellular response to organonitrogen compound GO:0071417 197 0.074
response to inorganic substance GO:0010035 377 0.074
Rat
response to molecule of bacterial origin GO:0002237 194 0.073
positive regulation of rna metabolic process GO:0051254 203 0.072
cellular chemical homeostasis GO:0055082 247 0.072
response to nutrient GO:0007584 248 0.071
cellular cation homeostasis GO:0030003 180 0.071
metal ion transport GO:0030001 289 0.071
secretion by cell GO:0032940 248 0.070
regulation of ion transport GO:0043269 245 0.068
Rat
learning or memory GO:0007611 90 0.068
response to other organism GO:0051707 220 0.066
secretion GO:0046903 307 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.064
regulation of molecular function GO:0065009 398 0.064
Rat
rna metabolic process GO:0016070 406 0.063
cyclic nucleotide metabolic process GO:0009187 80 0.063
regulation of phosphate metabolic process GO:0019220 349 0.062
regulation of nucleic acid templated transcription GO:1903506 380 0.062
regulation of programmed cell death GO:0043067 341 0.061
transmembrane transport GO:0055085 412 0.059
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.059
nucleoside phosphate biosynthetic process GO:1901293 102 0.058
purine ribonucleotide metabolic process GO:0009150 227 0.058
purine ribonucleotide biosynthetic process GO:0009152 81 0.057
carbohydrate derivative metabolic process GO:1901135 346 0.057
ribonucleotide biosynthetic process GO:0009260 85 0.057
response to growth factor GO:0070848 189 0.057
response to bacterium GO:0009617 200 0.056
regulation of nucleotide metabolic process GO:0006140 117 0.056
nucleoside phosphate metabolic process GO:0006753 283 0.056
response to cytokine GO:0034097 215 0.055
cellular response to endogenous stimulus GO:0071495 377 0.055
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.055
response to peptide hormone GO:0043434 278 0.055
cellular response to organic cyclic compound GO:0071407 202 0.054
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.053
regulation of apoptotic process GO:0042981 335 0.052
metanephric comma shaped body morphogenesis GO:0072278 2 0.052
regulation of camp biosynthetic process GO:0030817 38 0.049
nucleotide biosynthetic process GO:0009165 98 0.049
regulation of nucleotide biosynthetic process GO:0030808 47 0.047
positive regulation of nucleic acid templated transcription GO:1903508 197 0.047
positive regulation of intracellular signal transduction GO:1902533 138 0.047
positive regulation of cell death GO:0010942 184 0.047
organophosphate biosynthetic process GO:0090407 143 0.046
s shaped body morphogenesis GO:0072050 2 0.046
lipid metabolic process GO:0006629 283 0.044
regulation of transcription dna templated GO:0006355 374 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
acetyl coa metabolic process GO:0006084 17 0.040
cellular catabolic process GO:0044248 295 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.040
positive regulation of gene expression GO:0010628 244 0.040
cognition GO:0050890 92 0.040
chemical homeostasis GO:0048878 292 0.040
response to corticosteroid GO:0031960 235 0.040
response to acid chemical GO:0001101 222 0.040
cellular divalent inorganic cation homeostasis GO:0072503 162 0.039
Zebrafish
organic acid metabolic process GO:0006082 292 0.039
sodium ion transport GO:0006814 82 0.039
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.039
response to peptide GO:1901652 292 0.038
ion homeostasis GO:0050801 212 0.038
ribose phosphate metabolic process GO:0019693 235 0.037
proteolysis GO:0006508 175 0.037
programmed cell death GO:0012501 392 0.036
carbohydrate metabolic process GO:0005975 130 0.036
response to extracellular stimulus GO:0009991 380 0.036
divalent inorganic cation homeostasis GO:0072507 165 0.036
Zebrafish
response to lipopolysaccharide GO:0032496 191 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.036
neurological system process GO:0050877 219 0.035
organophosphate metabolic process GO:0019637 370 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.035
oxoacid metabolic process GO:0043436 290 0.034
comma shaped body morphogenesis GO:0072049 2 0.034
cyclic nucleotide biosynthetic process GO:0009190 63 0.034
regulation of transmembrane transport GO:0034762 122 0.033
Rat
positive regulation of synaptic transmission GO:0050806 62 0.033
response to starvation GO:0042594 59 0.033
camp metabolic process GO:0046058 63 0.033
regeneration GO:0031099 163 0.032
calcium ion homeostasis GO:0055074 162 0.032
Zebrafish
synaptic transmission GO:0007268 235 0.032
regulation of system process GO:0044057 208 0.032
Rat
purine nucleotide metabolic process GO:0006163 229 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
camp biosynthetic process GO:0006171 47 0.031
response to glucocorticoid GO:0051384 223 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
regulation of protein metabolic process GO:0051246 289 0.030
organic substance catabolic process GO:1901575 316 0.030
reproductive process GO:0022414 372 0.030
cellular response to growth factor stimulus GO:0071363 162 0.030
metanephric s shaped body morphogenesis GO:0072284 2 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
macromolecular complex assembly GO:0065003 273 0.029
positive regulation of cell communication GO:0010647 271 0.029
single organism catabolic process GO:0044712 283 0.029
carboxylic acid metabolic process GO:0019752 289 0.028
ion transmembrane transport GO:0034220 365 0.028
cellular component biogenesis GO:0044085 368 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
regulation of cellular localization GO:0060341 263 0.027
cellular component assembly GO:0022607 360 0.027
cellular homeostasis GO:0019725 252 0.027
macromolecular complex subunit organization GO:0043933 339 0.026
nitrogen compound transport GO:0071705 229 0.026
regulation of cell development GO:0060284 263 0.026
gamete generation GO:0007276 124 0.026
regulation of signal transduction GO:0009966 318 0.026
cation homeostasis GO:0055080 195 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
amine metabolic process GO:0009308 38 0.025
oxidation reduction process GO:0055114 304 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
cellular ion homeostasis GO:0006873 184 0.024
cellular response to glucocorticoid stimulus GO:0071385 68 0.024
response to metal ion GO:0010038 253 0.024
Rat
regulation of homeostatic process GO:0032844 101 0.024
regulation of cell differentiation GO:0045595 320 0.024
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 1 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
apoptotic process GO:0006915 381 0.023
regulation of membrane potential GO:0042391 110 0.023
Mouse Rat
protein complex assembly GO:0006461 263 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
regulation of muscle system process GO:0090257 79 0.023
Rat
gastrulation GO:0007369 2 0.023
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.023
cellular component movement GO:0006928 248 0.022
response to nutrient levels GO:0031667 370 0.022
protein phosphorylation GO:0006468 345 0.022
spermatogenesis GO:0007283 99 0.022
muscle system process GO:0003012 115 0.022
Rat
positive regulation of signal transduction GO:0009967 175 0.022
peptide hormone secretion GO:0030072 84 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
negative regulation of apoptotic process GO:0043066 181 0.021
nucleotide metabolic process GO:0009117 279 0.021
multicellular organismal homeostasis GO:0048871 49 0.021
cardiac muscle cell contraction GO:0086003 10 0.021
Rat
regulation of response to external stimulus GO:0032101 106 0.021
blood circulation GO:0008015 183 0.021
Zebrafish Rat
regulation of ion transmembrane transport GO:0034765 121 0.021
Rat
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.021
acute phase response GO:0006953 20 0.021
lipid biosynthetic process GO:0008610 128 0.021
response to carbohydrate GO:0009743 183 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
positive regulation of camp biosynthetic process GO:0030819 28 0.021
striated muscle contraction GO:0006941 44 0.021
Rat
regulation of locomotion GO:0040012 148 0.021
regulation of blood circulation GO:1903522 110 0.020
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.020
defense response GO:0006952 194 0.020
behavior GO:0007610 205 0.020
response to purine containing compound GO:0014074 126 0.020
regulation of catalytic activity GO:0050790 304 0.020
regulation of peptide transport GO:0090087 87 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
cellular amine metabolic process GO:0044106 38 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
protein complex subunit organization GO:0071822 302 0.020
response to oxygen levels GO:0070482 265 0.020
response to ethanol GO:0045471 162 0.020
amide transport GO:0042886 105 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
metanephric glomerulus development GO:0072224 3 0.019
homeostatic process GO:0042592 331 0.019
vesicle mediated transport GO:0016192 181 0.019
immune system process GO:0002376 204 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
negative regulation of metabolic process GO:0009892 331 0.019
circulatory system process GO:0003013 183 0.018
Zebrafish Rat
single organism carbohydrate metabolic process GO:0044723 118 0.018
lymphoid progenitor cell differentiation GO:0002320 2 0.018
regulation of hormone levels GO:0010817 187 0.018
heart contraction GO:0060047 57 0.018
Zebrafish Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
single organism intracellular transport GO:1902582 166 0.018
negative regulation of molecular function GO:0044092 133 0.018
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.018
divalent inorganic cation transport GO:0072511 134 0.018
Rat
regulation of multicellular organismal development GO:2000026 376 0.018
reproduction GO:0000003 245 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
multicellular organism reproduction GO:0032504 233 0.018
negative regulation of gene expression GO:0010629 199 0.018
regulation of peptide hormone secretion GO:0090276 80 0.017
central nervous system development GO:0007417 311 0.017
hormone transport GO:0009914 121 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
head development GO:0060322 247 0.017
insulin secretion GO:0030073 69 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of ion transport GO:0043270 94 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
Rat
single organism reproductive process GO:0044702 297 0.017
response to epidermal growth factor GO:0070849 18 0.017
response to nicotine GO:0035094 51 0.016
Rat
mapk cascade GO:0000165 140 0.016
regulation of ion transmembrane transporter activity GO:0032412 48 0.016
Rat
cellular amino acid metabolic process GO:0006520 107 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
inflammatory response GO:0006954 150 0.016
coronary vasculature morphogenesis GO:0060977 3 0.016
cellular protein complex assembly GO:0043623 44 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
regulation of hormone secretion GO:0046883 106 0.016
cardiac muscle contraction GO:0060048 27 0.016
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of neurogenesis GO:0050767 247 0.015
regulation of neurological system process GO:0031644 43 0.015
response to hexose GO:0009746 144 0.015
digestive system process GO:0022600 24 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.015
regulation of cyclase activity GO:0031279 21 0.015
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.015
single organism behavior GO:0044708 130 0.015
negative regulation of cell death GO:0060548 229 0.015
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.015
Rat
cellular response to cytokine stimulus GO:0071345 127 0.015
regulation of muscle contraction GO:0006937 53 0.015
Rat
negative regulation of response to stimulus GO:0048585 155 0.015
regulation of phosphorylation GO:0042325 248 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
regulation of insulin secretion GO:0050796 65 0.015
growth GO:0040007 165 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of molecular function GO:0044093 230 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
Zebrafish
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.014
intracellular transport GO:0046907 185 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
regulation of neuron death GO:1901214 115 0.014
negative regulation of nucleotide metabolic process GO:0045980 23 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
Zebrafish
calcium ion transport GO:0006816 131 0.014
Rat
acute inflammatory response GO:0002526 58 0.014
monosaccharide metabolic process GO:0005996 61 0.014
regulation of calcium ion transport GO:0051924 77 0.014
Rat
b cell differentiation GO:0030183 2 0.014
multi organism reproductive process GO:0044703 262 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
epithelium development GO:0060429 96 0.014
Zebrafish
response to temperature stimulus GO:0009266 94 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
muscle tissue morphogenesis GO:0060415 1 0.013
regulation of peptide secretion GO:0002791 82 0.013
catabolic process GO:0009056 351 0.013
phenylpropanoid catabolic process GO:0046271 3 0.013
cgmp biosynthetic process GO:0006182 15 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
regulation of protein modification process GO:0031399 194 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
Zebrafish
memory GO:0007613 54 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
Rat
negative regulation of transport GO:0051051 136 0.013
Rat
formation of primary germ layer GO:0001704 1 0.013
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.013
male gamete generation GO:0048232 99 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
cellular response to alcohol GO:0097306 87 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
long term synaptic potentiation GO:0060291 21 0.012
heart process GO:0003015 57 0.012
Zebrafish Rat
negative regulation of cellular component organization GO:0051129 83 0.012
peptidyl amino acid modification GO:0018193 126 0.012
single organism organelle organization GO:1902589 180 0.012
learning GO:0007612 33 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of lyase activity GO:0051339 22 0.012
insecticide metabolic process GO:0017143 4 0.012
protein oligomerization GO:0051259 191 0.012
response to glucose GO:0009749 136 0.012
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of interferon gamma production GO:0032649 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of amine transport GO:0051952 54 0.011
sensory perception GO:0007600 101 0.011
immune effector process GO:0002252 53 0.011
tolerance induction dependent upon immune response GO:0002461 2 0.011
cellular response to external stimulus GO:0071496 118 0.011
Rat
neurotransmitter gated ion channel clustering GO:0072578 3 0.011
regulation of neurotransmitter levels GO:0001505 42 0.011
protein autophosphorylation GO:0046777 66 0.011
peptide secretion GO:0002790 86 0.011
tube development GO:0035295 89 0.011
Zebrafish
response to wounding GO:0009611 254 0.011
regulation of camp metabolic process GO:0030814 43 0.011
cytoplasmic transport GO:0016482 115 0.011
response to increased oxygen levels GO:0036296 45 0.011
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.011
small molecule biosynthetic process GO:0044283 124 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
cellular ketone metabolic process GO:0042180 51 0.011
fertilization GO:0009566 3 0.011
Mouse
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of response to stress GO:0080134 126 0.010
regulation of cellular component movement GO:0051270 150 0.010
Rat
regulation of anion transport GO:0044070 43 0.010
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.010
regulation of response to wounding GO:1903034 69 0.010
glucose metabolic process GO:0006006 52 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
divalent metal ion transport GO:0070838 132 0.010
Rat
serotonin receptor signaling pathway GO:0007210 10 0.010
response to retinoic acid GO:0032526 63 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
t cell chemotaxis GO:0010818 2 0.010
response to tumor necrosis factor GO:0034612 56 0.010
response to amino acid GO:0043200 75 0.010

Atp1a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
muscular disease DOID:0080000 0 0.022
muscle tissue disease DOID:66 0 0.021
retinal disease DOID:5679 0 0.018
retinal degeneration DOID:8466 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
nervous system disease DOID:863 0 0.018
eye disease DOID:5614 0 0.018
myopathy DOID:423 0 0.011