Rattus norvegicus

0 known processes

Atp1b4

ATPase, (Na+)/K+ transporting, beta 4 polypeptide

(Aliases: Ac2-628)

Atp1b4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.194
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.149
metal ion transport GO:0030001 289 0.119
Rat
circulatory system development GO:0072359 134 0.080
protein complex assembly GO:0006461 263 0.078
organic acid metabolic process GO:0006082 292 0.077
regulation of molecular function GO:0065009 398 0.071
reproductive process GO:0022414 372 0.065
oxoacid metabolic process GO:0043436 290 0.064
intracellular signal transduction GO:0035556 314 0.063
regulation of intracellular signal transduction GO:1902531 218 0.060
single organism catabolic process GO:0044712 283 0.059
Rat
response to biotic stimulus GO:0009607 226 0.057
Rat
organic substance catabolic process GO:1901575 316 0.056
Rat
single organism biosynthetic process GO:0044711 342 0.056
protein complex subunit organization GO:0071822 302 0.050
regulation of metal ion transport GO:0010959 118 0.050
positive regulation of cell communication GO:0010647 271 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.048
aging GO:0007568 241 0.048
negative regulation of ion transport GO:0043271 51 0.048
cellular amine metabolic process GO:0044106 38 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
response to nutrient GO:0007584 248 0.047
cation homeostasis GO:0055080 195 0.046
cellular component movement GO:0006928 248 0.045
inorganic ion transmembrane transport GO:0098660 229 0.045
Rat
positive regulation of protein metabolic process GO:0051247 178 0.044
transmembrane transport GO:0055085 412 0.044
Rat
ion homeostasis GO:0050801 212 0.044
regulation of protein kinase activity GO:0045859 105 0.042
cellular component assembly GO:0022607 360 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
regulation of signal transduction GO:0009966 318 0.039
positive regulation of signal transduction GO:0009967 175 0.039
protein phosphorylation GO:0006468 345 0.039
monovalent inorganic cation transport GO:0015672 172 0.038
Rat
positive regulation of signaling GO:0023056 270 0.038
development of primary sexual characteristics GO:0045137 107 0.038
multicellular organism reproduction GO:0032504 233 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
macromolecular complex assembly GO:0065003 273 0.036
positive regulation of developmental process GO:0051094 283 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
regulation of phosphorylation GO:0042325 248 0.035
protein complex biogenesis GO:0070271 263 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.035
cardiovascular system development GO:0072358 134 0.035
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.034
response to growth factor GO:0070848 189 0.034
cellular component biogenesis GO:0044085 368 0.033
single organism reproductive process GO:0044702 297 0.033
response to nutrient levels GO:0031667 370 0.033
regeneration GO:0031099 163 0.033
multi organism reproductive process GO:0044703 262 0.033
response to bacterium GO:0009617 200 0.032
Rat
macromolecular complex subunit organization GO:0043933 339 0.032
organelle organization GO:0006996 266 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
biological adhesion GO:0022610 110 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cellular macromolecule localization GO:0070727 122 0.031
regulation of cellular component movement GO:0051270 150 0.031
cellular chemical homeostasis GO:0055082 247 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
positive regulation of cell proliferation GO:0008284 249 0.030
developmental process involved in reproduction GO:0003006 159 0.030
regulation of mapk cascade GO:0043408 116 0.030
negative regulation of molecular function GO:0044092 133 0.030
taxis GO:0042330 67 0.029
negative regulation of metabolic process GO:0009892 331 0.029
positive regulation of phosphorylation GO:0042327 177 0.029
actin filament based process GO:0030029 86 0.028
regulation of protein modification process GO:0031399 194 0.028
reproductive structure development GO:0048608 128 0.028
positive regulation of transport GO:0051050 245 0.028
proteolysis GO:0006508 175 0.028
female gonad development GO:0008585 53 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
sex differentiation GO:0007548 113 0.027
muscle structure development GO:0061061 87 0.027
ras protein signal transduction GO:0007265 29 0.026
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.026
coronary vasculature morphogenesis GO:0060977 3 0.026
calcium ion transport GO:0006816 131 0.026
rna metabolic process GO:0016070 406 0.026
Human
regulation of cellular protein metabolic process GO:0032268 267 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
chemical homeostasis GO:0048878 292 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
Rat
positive regulation of molecular function GO:0044093 230 0.025
ion transmembrane transport GO:0034220 365 0.025
Rat
purine containing compound metabolic process GO:0072521 253 0.025
Rat
regulation of cellular localization GO:0060341 263 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
response to decreased oxygen levels GO:0036293 237 0.024
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
Rat
cellular response to growth factor stimulus GO:0071363 162 0.024
cellular catabolic process GO:0044248 295 0.024
Rat
nucleic acid templated transcription GO:0097659 379 0.023
Human
divalent metal ion transport GO:0070838 132 0.023
muscle tissue development GO:0060537 58 0.023
regulation of ion transport GO:0043269 245 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
Rat
reproductive system development GO:0061458 128 0.023
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.022
regulation of cell differentiation GO:0045595 320 0.022
striated muscle tissue development GO:0014706 58 0.022
positive regulation of protein modification process GO:0031401 142 0.022
regulation of membrane potential GO:0042391 110 0.022
regulation of organ formation GO:0003156 2 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
positive regulation of protein kinase activity GO:0045860 73 0.022
transcription dna templated GO:0006351 377 0.021
Human
catabolic process GO:0009056 351 0.021
Rat
purine nucleotide metabolic process GO:0006163 229 0.021
Rat
regulation of programmed cell death GO:0043067 341 0.021
gonad development GO:0008406 104 0.021
reproduction GO:0000003 245 0.021
regulation of kinase activity GO:0043549 117 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
response to wounding GO:0009611 254 0.021
response to extracellular stimulus GO:0009991 380 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.020
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.020
nucleotide metabolic process GO:0009117 279 0.020
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.020
positive regulation of gene expression GO:0010628 244 0.020
gamete generation GO:0007276 124 0.020
regulation of stem cell differentiation GO:2000736 2 0.020
rhythmic process GO:0048511 156 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
limb morphogenesis GO:0035108 4 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
Rat
positive regulation of mapk cascade GO:0043410 92 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
carbohydrate metabolic process GO:0005975 130 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
apoptotic process GO:0006915 381 0.019
regulation of protein metabolic process GO:0051246 289 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
Rat
regulation of cell proliferation GO:0042127 359 0.019
organophosphate metabolic process GO:0019637 370 0.019
Rat
intracellular transport GO:0046907 185 0.019
oxidation reduction process GO:0055114 304 0.019
response to oxidative stress GO:0006979 186 0.019
negative regulation of cell death GO:0060548 229 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
Human
single organism organelle organization GO:1902589 180 0.019
respiratory system development GO:0060541 45 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
Rat
homeostatic process GO:0042592 331 0.018
cation transmembrane transport GO:0098655 263 0.018
Rat
regulation of apoptotic process GO:0042981 335 0.018
maintenance of location GO:0051235 17 0.018
central nervous system development GO:0007417 311 0.018
regulation of transcription dna templated GO:0006355 374 0.018
Human
regulation of transferase activity GO:0051338 123 0.018
cellular protein complex assembly GO:0043623 44 0.017
tissue development GO:0009888 252 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
secretion by cell GO:0032940 248 0.017
cellular response to stress GO:0033554 269 0.017
positive regulation of fat cell proliferation GO:0070346 1 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
Rat
positive regulation of programmed cell death GO:0043068 157 0.017
metal ion homeostasis GO:0055065 186 0.017
protein oligomerization GO:0051259 191 0.017
divalent inorganic cation transport GO:0072511 134 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of fat cell proliferation GO:0070344 1 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
cell cell signaling GO:0007267 335 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
small molecule catabolic process GO:0044282 59 0.016
axis specification GO:0009798 4 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
regulation of nervous system development GO:0051960 264 0.016
protein localization GO:0008104 191 0.016
positive regulation of kinase activity GO:0033674 77 0.016
rna biosynthetic process GO:0032774 380 0.016
Human
negative regulation of transport GO:0051051 136 0.016
regulation of rna biosynthetic process GO:2001141 381 0.015
Human
secretion GO:0046903 307 0.015
cell part morphogenesis GO:0032990 123 0.015
single organism intracellular transport GO:1902582 166 0.015
cell motility GO:0048870 202 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
regulation of cell development GO:0060284 263 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
cardiac muscle cell contraction GO:0086003 10 0.015
regulation of calcium ion transport GO:0051924 77 0.015
cellular ion homeostasis GO:0006873 184 0.015
response to oxygen levels GO:0070482 265 0.015
Rat
small gtpase mediated signal transduction GO:0007264 36 0.015
mapk cascade GO:0000165 140 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.015
endoplasmic reticulum to cytosol transport GO:1903513 4 0.015
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.015
regulation of neuron death GO:1901214 115 0.015
angiogenesis GO:0001525 53 0.015
female pregnancy GO:0007565 122 0.015
regulation of locomotion GO:0040012 148 0.014
organ induction GO:0001759 1 0.014
wound healing GO:0042060 122 0.014
muscle organ development GO:0007517 50 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
cell adhesion GO:0007155 110 0.014
response to lipopolysaccharide GO:0032496 191 0.014
Rat
cellular metal ion homeostasis GO:0006875 172 0.014
potassium ion transport GO:0006813 97 0.014
Rat
regulation of cytokine biosynthetic process GO:0042035 3 0.014
regulation of cellular component organization GO:0051128 368 0.014
head development GO:0060322 247 0.014
amine metabolic process GO:0009308 38 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
Rat
epithelial cell proliferation GO:0050673 54 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
Rat
female sex differentiation GO:0046660 59 0.014
cytoplasmic transport GO:0016482 115 0.014
response to hypoxia GO:0001666 231 0.014
Rat
cellular cation homeostasis GO:0030003 180 0.014
brain development GO:0007420 247 0.014
skeletal muscle cell differentiation GO:0035914 2 0.014
regulation of rna metabolic process GO:0051252 391 0.014
Human
regulation of homeostatic process GO:0032844 101 0.013
localization of cell GO:0051674 202 0.013
tube development GO:0035295 89 0.013
response to cytokine GO:0034097 215 0.013
regulation of hormone levels GO:0010817 187 0.013
response to other organism GO:0051707 220 0.013
Rat
calcium ion homeostasis GO:0055074 162 0.013
blood circulation GO:0008015 183 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
regulation of muscle tissue development GO:1901861 25 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular homeostasis GO:0019725 252 0.013
macromolecule localization GO:0033036 252 0.013
cellular protein localization GO:0034613 122 0.013
sequestering of calcium ion GO:0051208 8 0.013
organic acid catabolic process GO:0016054 49 0.013
regulation of neuron differentiation GO:0045664 208 0.012
appendage morphogenesis GO:0035107 4 0.012
cell migration GO:0016477 197 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
peptidyl amino acid modification GO:0018193 126 0.012
growth GO:0040007 165 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
alpha amino acid catabolic process GO:1901606 20 0.012
regulation of catabolic process GO:0009894 113 0.012
positive regulation of epithelial cell proliferation GO:0050679 32 0.012
locomotion GO:0040011 237 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
nucleotide catabolic process GO:0009166 139 0.012
Rat
aromatic compound catabolic process GO:0019439 168 0.012
Rat
regulation of catalytic activity GO:0050790 304 0.012
arachidonic acid metabolic process GO:0019369 20 0.012
regulation of defense response GO:0031347 68 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
positive regulation of cell death GO:0010942 184 0.012
response to external biotic stimulus GO:0043207 221 0.011
Rat
steroid biosynthetic process GO:0006694 48 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
Rat
immune system process GO:0002376 204 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
Rat
circulatory system process GO:0003013 183 0.011
positive regulation of transferase activity GO:0051347 81 0.011
defense response GO:0006952 194 0.011
sequestering of metal ion GO:0051238 9 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
heart morphogenesis GO:0003007 3 0.011
protein heterooligomerization GO:0051291 89 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular response to external stimulus GO:0071496 118 0.011
wnt signaling pathway calcium modulating pathway GO:0007223 1 0.011
positive regulation of cell motility GO:2000147 97 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
Rat
development of primary female sexual characteristics GO:0046545 56 0.011
hormone transport GO:0009914 121 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
vesicle mediated transport GO:0016192 181 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
lung development GO:0030324 43 0.010
neuron differentiation GO:0030182 368 0.010
heart development GO:0007507 72 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
heterocycle catabolic process GO:0046700 167 0.010
Rat
regulation of neurogenesis GO:0050767 247 0.010
negative regulation of cardiac muscle tissue development GO:0055026 3 0.010
immune response GO:0006955 104 0.010
cyclic purine nucleotide metabolic process GO:0052652 62 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
Rat
nucleotide biosynthetic process GO:0009165 98 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010

Atp1b4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
nervous system disease DOID:863 0 0.017