Rattus norvegicus

113 known processes

Atp5a1

ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

Atp5a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dicarboxylic acid metabolic process GO:0043648 42 0.998
aerobic respiration GO:0009060 13 0.997
tricarboxylic acid metabolic process GO:0072350 10 0.996
cofactor metabolic process GO:0051186 95 0.992
nadh metabolic process GO:0006734 10 0.974
coenzyme metabolic process GO:0006732 86 0.943
citrate metabolic process GO:0006101 3 0.938
cellular respiration GO:0045333 21 0.935
tricarboxylic acid cycle GO:0006099 11 0.922
adp biosynthetic process GO:0006172 8 0.895
energy derivation by oxidation of organic compounds GO:0015980 46 0.880
organic acid metabolic process GO:0006082 292 0.807
atp metabolic process GO:0046034 72 0.781
generation of precursor metabolites and energy GO:0006091 62 0.750
Fly
nucleotide metabolic process GO:0009117 279 0.709
nucleoside monophosphate metabolic process GO:0009123 93 0.698
ribonucleoside biosynthetic process GO:0042455 25 0.692
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.690
oxidation reduction process GO:0055114 304 0.673
Fly
purine ribonucleoside biosynthetic process GO:0046129 21 0.643
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.638
nucleobase containing small molecule metabolic process GO:0055086 316 0.577
adp metabolic process GO:0046031 8 0.566
purine nucleoside monophosphate metabolic process GO:0009126 84 0.539
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.531
glycosyl compound metabolic process GO:1901657 182 0.529
nicotinamide nucleotide metabolic process GO:0046496 28 0.516
nad metabolic process GO:0019674 15 0.501
purine nucleoside metabolic process GO:0042278 169 0.500
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.476
nucleoside triphosphate metabolic process GO:0009141 144 0.464
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.464
organophosphate metabolic process GO:0019637 370 0.454
cofactor biosynthetic process GO:0051188 28 0.445
pyridine containing compound metabolic process GO:0072524 32 0.398
oxoacid metabolic process GO:0043436 290 0.390
carbohydrate derivative metabolic process GO:1901135 346 0.356
carboxylic acid metabolic process GO:0019752 289 0.351
ribonucleoside triphosphate metabolic process GO:0009199 141 0.343
purine nucleotide biosynthetic process GO:0006164 83 0.337
purine nucleoside monophosphate catabolic process GO:0009128 55 0.329
purine nucleoside triphosphate metabolic process GO:0009144 141 0.321
purine ribonucleoside metabolic process GO:0046128 168 0.296
purine ribonucleotide metabolic process GO:0009150 227 0.288
nucleoside phosphate metabolic process GO:0006753 283 0.264
aromatic compound catabolic process GO:0019439 168 0.242
regulation of apoptotic process GO:0042981 335 0.237
malate metabolic process GO:0006108 5 0.236
purine nucleoside biosynthetic process GO:0042451 21 0.231
purine nucleoside triphosphate catabolic process GO:0009146 122 0.219
atp catabolic process GO:0006200 54 0.215
nucleoside monophosphate catabolic process GO:0009125 56 0.210
neurotransmitter uptake GO:0001504 3 0.210
ribonucleotide metabolic process GO:0009259 231 0.207
purine nucleoside diphosphate metabolic process GO:0009135 9 0.205
ribonucleoside diphosphate biosynthetic process GO:0009188 10 0.194
cation homeostasis GO:0055080 195 0.183
organelle organization GO:0006996 266 0.169
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.169
cellular homeostasis GO:0019725 252 0.164
organonitrogen compound catabolic process GO:1901565 179 0.161
ribonucleoside triphosphate catabolic process GO:0009203 122 0.160
organic substance catabolic process GO:1901575 316 0.158
regulation of programmed cell death GO:0043067 341 0.156
purine ribonucleotide biosynthetic process GO:0009152 81 0.154
anion transport GO:0006820 178 0.153
purine ribonucleotide catabolic process GO:0009154 136 0.151
positive regulation of atp biosynthetic process GO:2001171 2 0.151
ribonucleoside metabolic process GO:0009119 174 0.150
nucleoside monophosphate biosynthetic process GO:0009124 28 0.147
transmembrane transport GO:0055085 412 0.147
single organism catabolic process GO:0044712 283 0.144
glycosyl compound catabolic process GO:1901658 126 0.143
organophosphate biosynthetic process GO:0090407 143 0.142
single organism biosynthetic process GO:0044711 342 0.140
purine nucleotide metabolic process GO:0006163 229 0.129
locomotion GO:0040011 237 0.129
cellular chemical homeostasis GO:0055082 247 0.128
heme biosynthetic process GO:0006783 4 0.127
nucleoside metabolic process GO:0009116 179 0.125
ion transmembrane transport GO:0034220 365 0.122
nucleoside phosphate catabolic process GO:1901292 140 0.122
oxidative phosphorylation GO:0006119 4 0.120
purine nucleotide catabolic process GO:0006195 136 0.120
purine containing compound metabolic process GO:0072521 253 0.119
purine ribonucleoside diphosphate metabolic process GO:0009179 9 0.114
cell cell signaling GO:0007267 335 0.111
nucleoside diphosphate metabolic process GO:0009132 14 0.110
heterocycle catabolic process GO:0046700 167 0.110
oxidoreduction coenzyme metabolic process GO:0006733 31 0.108
organic cyclic compound catabolic process GO:1901361 175 0.103
cation transmembrane transport GO:0098655 263 0.102
ribonucleotide catabolic process GO:0009261 136 0.100
ribonucleotide biosynthetic process GO:0009260 85 0.099
pyridine nucleotide metabolic process GO:0019362 28 0.098
ribonucleoside monophosphate catabolic process GO:0009158 55 0.097
ion homeostasis GO:0050801 212 0.094
cellular ion homeostasis GO:0006873 184 0.093
ribonucleoside monophosphate metabolic process GO:0009161 88 0.090
cell cell signaling involved in cell fate commitment GO:0045168 2 0.090
l glutamate import GO:0051938 2 0.087
organophosphate catabolic process GO:0046434 148 0.087
organonitrogen compound biosynthetic process GO:1901566 167 0.084
purine nucleoside catabolic process GO:0006152 124 0.084
catabolic process GO:0009056 351 0.083
thioester metabolic process GO:0035383 28 0.083
carbohydrate derivative biosynthetic process GO:1901137 124 0.080
cellular nitrogen compound catabolic process GO:0044270 163 0.079
atp synthesis coupled electron transport GO:0042773 2 0.079
porphyrin containing compound metabolic process GO:0006778 8 0.078
purine containing compound biosynthetic process GO:0072522 85 0.076
nucleotide catabolic process GO:0009166 139 0.076
chemical homeostasis GO:0048878 292 0.076
cation transport GO:0006812 382 0.076
anatomical structure morphogenesis GO:0009653 298 0.075
substrate dependent cell migration GO:0006929 1 0.075
nucleoside triphosphate catabolic process GO:0009143 123 0.075
monovalent inorganic cation transport GO:0015672 172 0.074
positive regulation of cellular protein metabolic process GO:0032270 167 0.073
ribonucleoside catabolic process GO:0042454 126 0.072
positive regulation of molecular function GO:0044093 230 0.072
dicarboxylic acid transport GO:0006835 34 0.071
cellular component assembly GO:0022607 360 0.070
nucleoside catabolic process GO:0009164 126 0.069
protein processing GO:0016485 68 0.069
cellular metal ion homeostasis GO:0006875 172 0.067
single organism organelle organization GO:1902589 180 0.066
cellular cation homeostasis GO:0030003 180 0.065
regulation of cell proliferation GO:0042127 359 0.064
carbohydrate derivative catabolic process GO:1901136 147 0.061
nucleoside transport GO:0015858 8 0.061
acyl coa metabolic process GO:0006637 28 0.061
purine nucleoside diphosphate biosynthetic process GO:0009136 9 0.060
positive regulation of apoptotic process GO:0043065 154 0.059
vesicle mediated transport GO:0016192 181 0.059
Fly
regulation of atp biosynthetic process GO:2001169 2 0.059
rna metabolic process GO:0016070 406 0.056
transcription dna templated GO:0006351 377 0.056
nucleoside phosphate biosynthetic process GO:1901293 102 0.054
purine containing compound catabolic process GO:0072523 138 0.054
purine nucleoside triphosphate biosynthetic process GO:0009145 6 0.052
tetrapyrrole metabolic process GO:0033013 11 0.052
osteoblast differentiation GO:0001649 26 0.050
anion transmembrane transport GO:0098656 77 0.050
metal ion homeostasis GO:0055065 186 0.049
inorganic cation transmembrane transport GO:0098662 202 0.049
cell cycle GO:0007049 101 0.045
blood vessel morphogenesis GO:0048514 58 0.044
negative regulation of metabolic process GO:0009892 331 0.044
regulation of protein metabolic process GO:0051246 289 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
protein complex assembly GO:0006461 263 0.043
cell redox homeostasis GO:0045454 1 0.043
protein maturation GO:0051604 68 0.043
ribose phosphate biosynthetic process GO:0046390 87 0.043
connective tissue development GO:0061448 33 0.042
oxaloacetate metabolic process GO:0006107 6 0.042
positive regulation of cell proliferation GO:0008284 249 0.042
cellular component biogenesis GO:0044085 368 0.041
macromolecular complex assembly GO:0065003 273 0.041
mitochondrial calcium ion transport GO:0006851 2 0.041
nucleic acid templated transcription GO:0097659 379 0.041
porphyrin containing compound biosynthetic process GO:0006779 6 0.040
cardiovascular system development GO:0072358 134 0.040
carboxylic acid transport GO:0046942 115 0.039
apoptotic process GO:0006915 381 0.039
glycosyl compound biosynthetic process GO:1901659 25 0.039
response to peptide hormone GO:0043434 278 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
metal ion transport GO:0030001 289 0.036
response to nutrient levels GO:0031667 370 0.036
negative regulation of cell death GO:0060548 229 0.035
cell adhesion GO:0007155 110 0.035
inorganic ion transmembrane transport GO:0098660 229 0.034
regulation of molecular function GO:0065009 398 0.034
Fly
ribonucleoside diphosphate metabolic process GO:0009185 10 0.033
2 oxoglutarate metabolic process GO:0006103 6 0.033
nucleoside biosynthetic process GO:0009163 25 0.033
negative regulation of cell communication GO:0010648 158 0.032
nitrogen compound transport GO:0071705 229 0.032
ribonucleoside triphosphate biosynthetic process GO:0009201 7 0.032
rna biosynthetic process GO:0032774 380 0.031
single organism intracellular transport GO:1902582 166 0.031
nucleotide biosynthetic process GO:0009165 98 0.031
dna integrity checkpoint GO:0031570 2 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.030
response to nutrient GO:0007584 248 0.030
positive regulation of hydrolase activity GO:0051345 86 0.030
regulation of transcription dna templated GO:0006355 374 0.030
nucleoside triphosphate biosynthetic process GO:0009142 8 0.030
mitochondrion organization GO:0007005 35 0.029
circulatory system development GO:0072359 134 0.029
regulation of rna metabolic process GO:0051252 391 0.029
response to decreased oxygen levels GO:0036293 237 0.029
positive regulation of cell death GO:0010942 184 0.028
isocitrate metabolic process GO:0006102 5 0.028
programmed cell death GO:0012501 392 0.028
aging GO:0007568 241 0.027
vasculature development GO:0001944 70 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
metanephric epithelium development GO:0072207 4 0.026
organic anion transport GO:0015711 132 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
single organism reproductive process GO:0044702 297 0.026
Fly
anatomical structure formation involved in morphogenesis GO:0048646 83 0.025
succinate metabolic process GO:0006105 7 0.025
central nervous system development GO:0007417 311 0.025
protein complex biogenesis GO:0070271 263 0.025
response to oxidative stress GO:0006979 186 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
adenine nucleotide transport GO:0051503 2 0.023
protein complex subunit organization GO:0071822 302 0.023
response to ethanol GO:0045471 162 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of cell differentiation GO:0045595 320 0.023
intracellular transport GO:0046907 185 0.023
response to fatty acid GO:0070542 65 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
divalent inorganic cation transport GO:0072511 134 0.023
renal system development GO:0072001 67 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
negative regulation of gene expression GO:0010629 199 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
chemosensory behavior GO:0007635 2 0.022
regulation of growth GO:0040008 105 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
homeostatic process GO:0042592 331 0.020
regulation of cell adhesion GO:0030155 52 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
regulation of membrane potential GO:0042391 110 0.020
response to extracellular stimulus GO:0009991 380 0.020
cell motility GO:0048870 202 0.020
localization of cell GO:0051674 202 0.020
proteolysis GO:0006508 175 0.020
ribonucleoside monophosphate biosynthetic process GO:0009156 24 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
cellular response to acid chemical GO:0071229 75 0.019
metanephric tubule development GO:0072170 4 0.019
protein localization GO:0008104 191 0.019
positive regulation of mitochondrial membrane permeability GO:0035794 1 0.018
sulfur compound metabolic process GO:0006790 70 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
macromolecule localization GO:0033036 252 0.018
Fly
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular component movement GO:0006928 248 0.017
ovulation cycle GO:0042698 67 0.017
regulation of proteolysis GO:0030162 66 0.017
biological adhesion GO:0022610 110 0.017
nucleoside diphosphate biosynthetic process GO:0009133 12 0.017
membrane organization GO:0061024 94 0.017
multicellular organismal reproductive process GO:0048609 233 0.016
Fly
response to alkaloid GO:0043279 132 0.016
calcium ion transport GO:0006816 131 0.016
cellular macromolecule localization GO:0070727 122 0.016
intracellular signal transduction GO:0035556 314 0.016
receptor mediated endocytosis GO:0006898 42 0.016
regulation of cellular component organization GO:0051128 368 0.015
response to mechanical stimulus GO:0009612 134 0.015
spindle organization GO:0007051 2 0.015
negative regulation of signaling GO:0023057 157 0.015
negative regulation of growth GO:0045926 37 0.015
adp transport GO:0015866 1 0.015
response to peptide GO:1901652 292 0.015
cellular response to external stimulus GO:0071496 118 0.015
cytoskeleton organization GO:0007010 111 0.014
activation of cysteine type endopeptidase activity GO:0097202 4 0.014
organic acid transport GO:0015849 116 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
nucleic acid transport GO:0050657 3 0.014
muscle cell differentiation GO:0042692 52 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
response to acid chemical GO:0001101 222 0.014
liver development GO:0001889 90 0.013
response to toxic substance GO:0009636 133 0.013
regulation of hydrolase activity GO:0051336 143 0.013
negative regulation of signal transduction GO:0009968 83 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
mitochondrial transport GO:0006839 19 0.013
response to cytokine GO:0034097 215 0.013
regulation of signal transduction GO:0009966 318 0.013
aspartate family amino acid biosynthetic process GO:0009067 4 0.013
negative regulation of autophagy GO:0010507 1 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of cellular localization GO:0060341 263 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
brain development GO:0007420 247 0.012
positive regulation of transport GO:0051050 245 0.012
response to hexose GO:0009746 144 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of nervous system development GO:0051960 264 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
lipid metabolic process GO:0006629 283 0.012
response to purine containing compound GO:0014074 126 0.011
rhythmic process GO:0048511 156 0.011
reproductive process GO:0022414 372 0.011
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
regulation of endopeptidase activity GO:0052548 51 0.011
kidney development GO:0001822 67 0.011
response to activity GO:0014823 73 0.011
synaptic transmission GO:0007268 235 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
reproductive structure development GO:0048608 128 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
multi multicellular organism process GO:0044706 138 0.011
cellular amine metabolic process GO:0044106 38 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
reproduction GO:0000003 245 0.011
Fly
peptidyl amino acid modification GO:0018193 126 0.011
cell migration GO:0016477 197 0.011
inorganic anion transmembrane transport GO:0098661 35 0.011
synapse organization GO:0050808 46 0.011
isotype switching GO:0045190 1 0.011
lipid localization GO:0010876 62 0.010
Fly
cellular response to stress GO:0033554 269 0.010
regulation of ph GO:0006885 13 0.010
single organism cellular localization GO:1902580 102 0.010
head development GO:0060322 247 0.010
necroptotic process GO:0070266 2 0.010

Atp5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
nervous system disease DOID:863 0 0.070
retinal disease DOID:5679 0 0.061
retinal degeneration DOID:8466 0 0.061
sensory system disease DOID:0050155 0 0.061
eye and adnexa disease DOID:1492 0 0.061
eye disease DOID:5614 0 0.061
central nervous system disease DOID:331 0 0.060
disease of metabolism DOID:0014667 0 0.036
amino acid metabolic disorder DOID:9252 0 0.036
inherited metabolic disorder DOID:655 0 0.036
organic acidemia DOID:0060159 0 0.036
disease of cellular proliferation DOID:14566 0 0.024
gastrointestinal system cancer DOID:3119 0 0.021
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.021
benign neoplasm DOID:0060072 0 0.018
retinitis pigmentosa DOID:10584 0 0.017