Rattus norvegicus

7 known processes

B2m

beta-2 microglobulin

B2m biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.629
positive regulation of tolerance induction GO:0002645 1 0.480
wound healing GO:0042060 122 0.455
regulation of tolerance induction to nonself antigen GO:0002655 1 0.398
female pregnancy GO:0007565 122 0.395
t cell tolerance induction GO:0002517 3 0.354
cellular catabolic process GO:0044248 295 0.269
regulation of phosphorus metabolic process GO:0051174 349 0.224
response to estradiol GO:0032355 164 0.217
reproductive process GO:0022414 372 0.206
negative regulation of cell death GO:0060548 229 0.206
tissue development GO:0009888 252 0.202
organic substance catabolic process GO:1901575 316 0.197
innate immune response GO:0045087 35 0.189
carboxylic acid metabolic process GO:0019752 289 0.188
cellular amino acid metabolic process GO:0006520 107 0.184
peptide metabolic process GO:0006518 32 0.181
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.171
multi organism reproductive process GO:0044703 262 0.166
hemostasis GO:0007599 26 0.151
cell killing GO:0001906 13 0.140
Mouse
regulation of blood coagulation GO:0030193 9 0.135
catabolic process GO:0009056 351 0.134
cellular response to stress GO:0033554 269 0.126
positive regulation of cell proliferation GO:0008284 249 0.126
regulation of apoptotic process GO:0042981 335 0.123
blood coagulation GO:0007596 26 0.122
regulation of protein metabolic process GO:0051246 289 0.122
regulation of body fluid levels GO:0050878 90 0.121
signal transduction by phosphorylation GO:0023014 144 0.115
proteolysis GO:0006508 175 0.110
mapk cascade GO:0000165 140 0.110
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.110
organic acid metabolic process GO:0006082 292 0.109
cellular response to iron ion starvation GO:0010106 1 0.109
programmed cell death GO:0012501 392 0.105
macromolecule catabolic process GO:0009057 58 0.104
oxoacid metabolic process GO:0043436 290 0.097
regulation of cell proliferation GO:0042127 359 0.096
aging GO:0007568 241 0.094
lipid biosynthetic process GO:0008610 128 0.092
single organism catabolic process GO:0044712 283 0.090
regulation of phosphate metabolic process GO:0019220 349 0.087
regulation of cellular amino acid metabolic process GO:0006521 2 0.086
regulation of anatomical structure morphogenesis GO:0022603 141 0.085
cellular amide metabolic process GO:0043603 44 0.084
response to peptide GO:1901652 292 0.083
negative regulation of response to stimulus GO:0048585 155 0.080
cellular ketone metabolic process GO:0042180 51 0.078
single organism reproductive process GO:0044702 297 0.078
response to glucocorticoid GO:0051384 223 0.077
positive regulation of developmental process GO:0051094 283 0.077
response to estrogen GO:0043627 232 0.076
negative regulation of metabolic process GO:0009892 331 0.075
regulation of cellular ketone metabolic process GO:0010565 27 0.073
response to inorganic substance GO:0010035 377 0.069
multicellular organism reproduction GO:0032504 233 0.068
positive regulation of response to stimulus GO:0048584 285 0.066
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.065
synaptic transmission GO:0007268 235 0.062
protein localization GO:0008104 191 0.061
nucleoside metabolic process GO:0009116 179 0.060
protein complex biogenesis GO:0070271 263 0.058
glycosyl compound metabolic process GO:1901657 182 0.058
single organism biosynthetic process GO:0044711 342 0.058
negative regulation of response to external stimulus GO:0032102 37 0.058
regulation of vasculature development GO:1901342 44 0.058
response to nutrient levels GO:0031667 370 0.057
organ regeneration GO:0031100 101 0.055
negative regulation of rna metabolic process GO:0051253 123 0.055
multicellular organismal reproductive process GO:0048609 233 0.054
atp metabolic process GO:0046034 72 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.052
circulatory system development GO:0072359 134 0.051
nucleotide metabolic process GO:0009117 279 0.050
protein maturation GO:0051604 68 0.050
positive regulation of mapk cascade GO:0043410 92 0.050
protein phosphorylation GO:0006468 345 0.049
protein complex assembly GO:0006461 263 0.048
carbohydrate derivative metabolic process GO:1901135 346 0.048
defense response GO:0006952 194 0.047
positive regulation of signaling GO:0023056 270 0.047
organic cyclic compound catabolic process GO:1901361 175 0.047
epithelium development GO:0060429 96 0.047
cellular response to oxidative stress GO:0034599 76 0.047
intracellular signal transduction GO:0035556 314 0.047
amine metabolic process GO:0009308 38 0.047
regulation of signal transduction GO:0009966 318 0.045
coagulation GO:0050817 28 0.045
regulation of locomotion GO:0040012 148 0.045
striated muscle tissue development GO:0014706 58 0.044
response to amine GO:0014075 46 0.044
positive regulation of phosphate metabolic process GO:0045937 262 0.043
negative regulation of cell killing GO:0031342 5 0.043
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.042
organonitrogen compound catabolic process GO:1901565 179 0.042
respiratory system development GO:0060541 45 0.042
response to glucose GO:0009749 136 0.041
homeostatic process GO:0042592 331 0.041
Human Mouse
regulation of tolerance induction GO:0002643 2 0.041
response to monosaccharide GO:0034284 159 0.041
regulation of transcription dna templated GO:0006355 374 0.040
regulation of catalytic activity GO:0050790 304 0.040
muscle structure development GO:0061061 87 0.039
regulation of molecular function GO:0065009 398 0.039
cellular component movement GO:0006928 248 0.039
chemical homeostasis GO:0048878 292 0.039
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
response to hexose GO:0009746 144 0.038
cellular response to organic cyclic compound GO:0071407 202 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
response to carbohydrate GO:0009743 183 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
response to starvation GO:0042594 59 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
response to acid chemical GO:0001101 222 0.036
positive regulation of cell communication GO:0010647 271 0.036
ribonucleotide metabolic process GO:0009259 231 0.036
secretion GO:0046903 307 0.035
response to cytokine GO:0034097 215 0.035
regulation of cell differentiation GO:0045595 320 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
sexual reproduction GO:0019953 148 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
regulation of programmed cell death GO:0043067 341 0.034
regulation of intracellular signal transduction GO:1902531 218 0.033
positive regulation of catalytic activity GO:0043085 184 0.033
negative regulation of apoptotic process GO:0043066 181 0.033
regulation of phosphorylation GO:0042325 248 0.033
morphogenesis of an epithelium GO:0002009 20 0.032
reproductive structure development GO:0048608 128 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
negative regulation of rna biosynthetic process GO:1902679 118 0.032
response to retinoic acid GO:0032526 63 0.032
reproduction GO:0000003 245 0.032
response to growth factor GO:0070848 189 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.031
muscle tissue development GO:0060537 58 0.030
organophosphate biosynthetic process GO:0090407 143 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
cellular protein catabolic process GO:0044257 19 0.029
carbohydrate derivative catabolic process GO:1901136 147 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
regulation of cellular component movement GO:0051270 150 0.029
positive regulation of cell death GO:0010942 184 0.029
cellular response to external stimulus GO:0071496 118 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
response to metal ion GO:0010038 253 0.028
positive regulation of cellular component organization GO:0051130 200 0.028
multi multicellular organism process GO:0044706 138 0.028
small molecule biosynthetic process GO:0044283 124 0.028
prostanoid metabolic process GO:0006692 12 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
purine nucleoside metabolic process GO:0042278 169 0.027
response to corticosteroid GO:0031960 235 0.027
regulation of protein modification process GO:0031399 194 0.027
positive regulation of cell differentiation GO:0045597 217 0.026
tissue morphogenesis GO:0048729 22 0.026
regulation of cellular component organization GO:0051128 368 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.026
prostaglandin metabolic process GO:0006693 12 0.026
response to bacterium GO:0009617 200 0.026
Mouse
fatty acid derivative metabolic process GO:1901568 38 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.025
aromatic compound catabolic process GO:0019439 168 0.025
macromolecule localization GO:0033036 252 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
brain development GO:0007420 247 0.024
response to extracellular stimulus GO:0009991 380 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
protein oligomerization GO:0051259 191 0.023
metanephros development GO:0001656 14 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
spermatogenesis GO:0007283 99 0.023
lymphocyte mediated immunity GO:0002449 14 0.023
Mouse
male sex differentiation GO:0046661 64 0.022
prostaglandin biosynthetic process GO:0001516 12 0.022
macromolecular complex assembly GO:0065003 273 0.022
organophosphate metabolic process GO:0019637 370 0.022
gland development GO:0048732 155 0.022
negative regulation of cell proliferation GO:0008285 119 0.021
positive regulation of cell development GO:0010720 176 0.021
collagen metabolic process GO:0032963 21 0.021
nucleoside catabolic process GO:0009164 126 0.021
regulation of response to stress GO:0080134 126 0.021
single organism intracellular transport GO:1902582 166 0.021
apoptotic process GO:0006915 381 0.021
activation of cysteine type endopeptidase activity GO:0097202 4 0.021
glycosyl compound catabolic process GO:1901658 126 0.020
regulation of viral entry into host cell GO:0046596 3 0.020
positive regulation of transport GO:0051050 245 0.020
negative regulation of immune system process GO:0002683 39 0.020
vascular endothelial growth factor signaling pathway GO:0038084 4 0.020
negative regulation of leukocyte apoptotic process GO:2000107 4 0.020
establishment of protein localization GO:0045184 141 0.020
epithelial cell differentiation GO:0030855 71 0.020
immune response GO:0006955 104 0.019
Mouse
regulation of ion transport GO:0043269 245 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
maternal process involved in female pregnancy GO:0060135 38 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
cellular response to starvation GO:0009267 27 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
positive regulation of cell motility GO:2000147 97 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
neuron development GO:0048666 286 0.018
cellular component assembly GO:0022607 360 0.018
protein catabolic process GO:0030163 30 0.018
positive regulation of molecular function GO:0044093 230 0.018
protein homooligomerization GO:0051260 91 0.018
negative regulation of gene expression GO:0010629 199 0.018
negative regulation of cell communication GO:0010648 158 0.018
blood vessel morphogenesis GO:0048514 58 0.018
regulation of response to external stimulus GO:0032101 106 0.018
vesicle mediated transport GO:0016192 181 0.018
rna biosynthetic process GO:0032774 380 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
regulation of hydrolase activity GO:0051336 143 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of behavior GO:0048520 38 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
immune effector process GO:0002252 53 0.017
Mouse
response to wounding GO:0009611 254 0.017
peptidyl amino acid modification GO:0018193 126 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
rna metabolic process GO:0016070 406 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.016
protein processing GO:0016485 68 0.016
vasculature development GO:0001944 70 0.016
negative regulation of innate immune response GO:0045824 4 0.016
developmental process involved in reproduction GO:0003006 159 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
gamete generation GO:0007276 124 0.015
regulation of rna metabolic process GO:0051252 391 0.015
acute inflammatory response GO:0002526 58 0.015
schwann cell migration GO:0036135 2 0.015
intracellular transport GO:0046907 185 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
epithelial cell proliferation GO:0050673 54 0.015
response to mechanical stimulus GO:0009612 134 0.015
establishment of vesicle localization GO:0051650 31 0.015
head development GO:0060322 247 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
adaptive immune response GO:0002250 14 0.014
Mouse
skeletal muscle tissue development GO:0007519 31 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.014
regulation of cellular localization GO:0060341 263 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
lymphocyte activation GO:0046649 43 0.013
Mouse
leukocyte mediated cytotoxicity GO:0001909 10 0.013
Mouse
regulation of synaptic transmission GO:0050804 141 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
development of primary sexual characteristics GO:0045137 107 0.012
negative regulation of defense response GO:0031348 19 0.012
negative regulation of leukocyte mediated immunity GO:0002704 6 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
peptide secretion GO:0002790 86 0.012
ribonucleoside monophosphate catabolic process GO:0009158 55 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
autophagic cell death GO:0048102 4 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cellular protein localization GO:0034613 122 0.012
response to ketone GO:1901654 182 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 4 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
regulation of defense response GO:0031347 68 0.012
positive regulation of fibroblast proliferation GO:0048146 15 0.012
cellular response to mechanical stimulus GO:0071260 48 0.011
regulation of immune effector process GO:0002697 32 0.011
Mouse
reproductive system development GO:0061458 128 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
protein transport GO:0015031 132 0.011
gonad development GO:0008406 104 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
regulation of neuron projection development GO:0010975 161 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
positive regulation of protein modification process GO:0031401 142 0.011
central nervous system development GO:0007417 311 0.011
chaperone mediated protein folding requiring cofactor GO:0051085 2 0.011
positive regulation of gene expression GO:0010628 244 0.011
growth GO:0040007 165 0.010
regulation of angiogenesis GO:0045765 39 0.010
purine containing compound catabolic process GO:0072523 138 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
cellular macromolecule catabolic process GO:0044265 29 0.010
cell migration GO:0016477 197 0.010
behavior GO:0007610 205 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
metal ion transport GO:0030001 289 0.010
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.010
glutamate receptor signaling pathway GO:0007215 43 0.010
purine containing compound metabolic process GO:0072521 253 0.010
purine nucleoside monophosphate catabolic process GO:0009128 55 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010

B2m disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.082
hematopoietic system disease DOID:74 0 0.082
blood protein disease DOID:620 0 0.082
agammaglobulinemia DOID:2583 0 0.082
b cell deficiency DOID:2115 0 0.082
immune system disease DOID:2914 0 0.082
disease of anatomical entity DOID:7 0 0.082
nervous system disease DOID:863 0 0.017
degeneration of macula and posterior pole DOID:2007 0 0.011
sensory system disease DOID:0050155 0 0.011
retinal degeneration DOID:8466 0 0.011
eye and adnexa disease DOID:1492 0 0.011
age related macular degeneration DOID:10871 0 0.011
retinal disease DOID:5679 0 0.011
macular degeneration DOID:4448 0 0.011
eye disease DOID:5614 0 0.011