Rattus norvegicus

63 known processes

Bad

BCL2-associated agonist of cell death

(Aliases: MGC72439)

Bad biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of catalytic activity GO:0050790 304 0.200
signal transduction by phosphorylation GO:0023014 144 0.155
intracellular signal transduction GO:0035556 314 0.119
regulation of programmed cell death GO:0043067 341 0.115
regulation of molecular function GO:0065009 398 0.114
regulation of phosphate metabolic process GO:0019220 349 0.113
positive regulation of signaling GO:0023056 270 0.106
regulation of phosphorus metabolic process GO:0051174 349 0.094
response to inorganic substance GO:0010035 377 0.084
protein complex assembly GO:0006461 263 0.079
positive regulation of molecular function GO:0044093 230 0.074
mapk cascade GO:0000165 140 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.070
neuron differentiation GO:0030182 368 0.066
positive regulation of phosphate metabolic process GO:0045937 262 0.065
organelle organization GO:0006996 266 0.064
protein complex subunit organization GO:0071822 302 0.063
protein phosphorylation GO:0006468 345 0.063
regulation of phosphorylation GO:0042325 248 0.062
regulation of cell proliferation GO:0042127 359 0.060
response to oxygen levels GO:0070482 265 0.059
negative regulation of metabolic process GO:0009892 331 0.058
positive regulation of protein metabolic process GO:0051247 178 0.057
regulation of mapk cascade GO:0043408 116 0.057
cellular component movement GO:0006928 248 0.057
reproduction GO:0000003 245 0.055
negative regulation of macromolecule metabolic process GO:0010605 260 0.053
single organism carbohydrate metabolic process GO:0044723 118 0.053
regulation of transcription dna templated GO:0006355 374 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
positive regulation of cell differentiation GO:0045597 217 0.051
response to peptide hormone GO:0043434 278 0.050
regulation of transferase activity GO:0051338 123 0.050
regulation of nucleic acid templated transcription GO:1903506 380 0.049
transcription dna templated GO:0006351 377 0.049
macromolecular complex subunit organization GO:0043933 339 0.049
response to peptide GO:1901652 292 0.047
apoptotic process GO:0006915 381 0.047
positive regulation of cellular protein metabolic process GO:0032270 167 0.047
locomotion GO:0040011 237 0.046
programmed cell death GO:0012501 392 0.045
cation transport GO:0006812 382 0.045
cell cell signaling GO:0007267 335 0.044
oxidation reduction process GO:0055114 304 0.044
regulation of cellular component organization GO:0051128 368 0.042
transmembrane transport GO:0055085 412 0.042
aging GO:0007568 241 0.042
negative regulation of cell death GO:0060548 229 0.042
regulation of signal transduction GO:0009966 318 0.042
protein oligomerization GO:0051259 191 0.042
negative regulation of protein metabolic process GO:0051248 114 0.041
regulation of intracellular signal transduction GO:1902531 218 0.040
neuron development GO:0048666 286 0.040
cell projection organization GO:0030030 302 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
regulation of hydrolase activity GO:0051336 143 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
positive regulation of protein modification process GO:0031401 142 0.038
amine metabolic process GO:0009308 38 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
neuron projection development GO:0031175 273 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
homeostatic process GO:0042592 331 0.037
cellular amine metabolic process GO:0044106 38 0.037
macromolecular complex assembly GO:0065003 273 0.037
negative regulation of neuron death GO:1901215 69 0.037
cell cycle checkpoint GO:0000075 2 0.037
proteolysis GO:0006508 175 0.037
response to carbohydrate GO:0009743 183 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
carbohydrate metabolic process GO:0005975 130 0.036
regulation of cellular amino acid metabolic process GO:0006521 2 0.036
cellular response to stress GO:0033554 269 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
positive regulation of catalytic activity GO:0043085 184 0.035
positive regulation of phosphorylation GO:0042327 177 0.034
positive regulation of developmental process GO:0051094 283 0.034
secretion GO:0046903 307 0.034
cellular carbohydrate metabolic process GO:0044262 72 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
tissue development GO:0009888 252 0.032
response to ketone GO:1901654 182 0.032
regulation of neurogenesis GO:0050767 247 0.032
protein complex biogenesis GO:0070271 263 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
response to nutrient levels GO:0031667 370 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
regulation of neuron death GO:1901214 115 0.031
regulation of protein modification process GO:0031399 194 0.030
regulation of neuron differentiation GO:0045664 208 0.030
regulation of cellular localization GO:0060341 263 0.030
positive regulation of gene expression GO:0010628 244 0.030
regulation of protein metabolic process GO:0051246 289 0.030
organophosphate metabolic process GO:0019637 370 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
negative regulation of apoptotic process GO:0043066 181 0.028
positive regulation of nervous system development GO:0051962 178 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
metal ion transport GO:0030001 289 0.028
cell projection morphogenesis GO:0048858 123 0.027
cellular component biogenesis GO:0044085 368 0.027
cell part morphogenesis GO:0032990 123 0.027
cation homeostasis GO:0055080 195 0.027
cell motility GO:0048870 202 0.026
cellular ketone metabolic process GO:0042180 51 0.026
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of intracellular signal transduction GO:1902533 138 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
positive regulation of cell communication GO:0010647 271 0.026
positive regulation of signal transduction GO:0009967 175 0.025
positive regulation of transport GO:0051050 245 0.025
muscle structure development GO:0061061 87 0.025
rna metabolic process GO:0016070 406 0.025
response to corticosteroid GO:0031960 235 0.025
regulation of immune system process GO:0002682 123 0.025
circulatory system development GO:0072359 134 0.024
cell cycle GO:0007049 101 0.024
response to estradiol GO:0032355 164 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
secretion by cell GO:0032940 248 0.024
cellular component assembly GO:0022607 360 0.023
positive regulation of mapk cascade GO:0043410 92 0.023
response to growth factor GO:0070848 189 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
polysaccharide metabolic process GO:0005976 25 0.023
regulation of nervous system development GO:0051960 264 0.023
cellular catabolic process GO:0044248 295 0.023
erk1 and erk2 cascade GO:0070371 48 0.023
cell morphogenesis GO:0000902 142 0.023
response to glucocorticoid GO:0051384 223 0.023
eye development GO:0001654 50 0.023
peptidyl amino acid modification GO:0018193 126 0.023
regulation of anatomical structure size GO:0090066 135 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
peptidyl serine phosphorylation GO:0018105 33 0.023
organelle localization GO:0051640 55 0.023
positive regulation of neurogenesis GO:0050769 165 0.022
muscle tissue development GO:0060537 58 0.022
regulation of cell development GO:0060284 263 0.022
response to nutrient GO:0007584 248 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
single organism biosynthetic process GO:0044711 342 0.021
regeneration GO:0031099 163 0.021
regulation of cell migration GO:0030334 128 0.021
cardiovascular system development GO:0072358 134 0.021
catabolic process GO:0009056 351 0.021
response to hexose GO:0009746 144 0.021
immune response GO:0006955 104 0.021
regulation of locomotion GO:0040012 148 0.020
regulation of neuron apoptotic process GO:0043523 83 0.020
response to extracellular stimulus GO:0009991 380 0.020
response to toxic substance GO:0009636 133 0.020
rna biosynthetic process GO:0032774 380 0.020
response to glucose GO:0009749 136 0.020
single organism organelle organization GO:1902589 180 0.020
cellular chemical homeostasis GO:0055082 247 0.019
embryo development GO:0009790 49 0.019
nucleic acid templated transcription GO:0097659 379 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
regulation of kinase activity GO:0043549 117 0.019
positive regulation of cell death GO:0010942 184 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
regulation of catabolic process GO:0009894 113 0.018
regulation of dendrite morphogenesis GO:0048814 33 0.018
regulation of rna metabolic process GO:0051252 391 0.018
protein localization GO:0008104 191 0.018
cyclic nucleotide metabolic process GO:0009187 80 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
positive regulation of cell development GO:0010720 176 0.017
behavior GO:0007610 205 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
cellular homeostasis GO:0019725 252 0.017
response to insulin GO:0032868 133 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
positive regulation of kinase activity GO:0033674 77 0.017
negative regulation of molecular function GO:0044092 133 0.017
organ regeneration GO:0031100 101 0.017
anatomical structure morphogenesis GO:0009653 298 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
dna metabolic process GO:0006259 96 0.016
regulation of cell differentiation GO:0045595 320 0.016
brain development GO:0007420 247 0.016
chemical homeostasis GO:0048878 292 0.016
response to wounding GO:0009611 254 0.016
cell growth GO:0016049 104 0.016
rhythmic process GO:0048511 156 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
multi organism reproductive process GO:0044703 262 0.016
regulation of membrane potential GO:0042391 110 0.016
heart morphogenesis GO:0003007 3 0.016
chromosome organization GO:0051276 36 0.015
single organism behavior GO:0044708 130 0.015
localization of cell GO:0051674 202 0.015
regulation of oxidoreductase activity GO:0051341 11 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cytoskeleton organization GO:0007010 111 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to hypoxia GO:0001666 231 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
cellular component morphogenesis GO:0032989 155 0.015
camera type eye development GO:0043010 48 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
circulatory system process GO:0003013 183 0.014
regulation of cell motility GO:2000145 131 0.014
nucleotide metabolic process GO:0009117 279 0.014
response to oxidative stress GO:0006979 186 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular response to external stimulus GO:0071496 118 0.014
endocytosis GO:0006897 84 0.014
central nervous system development GO:0007417 311 0.014
regulation of protein kinase activity GO:0045859 105 0.014
regulation of dendrite development GO:0050773 59 0.014
generation of precursor metabolites and energy GO:0006091 62 0.014
neuron apoptotic process GO:0051402 88 0.014
reproductive process GO:0022414 372 0.014
synaptic transmission GO:0007268 235 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
response to mechanical stimulus GO:0009612 134 0.014
circadian regulation of gene expression GO:0032922 3 0.014
response to acid chemical GO:0001101 222 0.014
neuron projection morphogenesis GO:0048812 122 0.014
cellular ion homeostasis GO:0006873 184 0.014
striated muscle tissue development GO:0014706 58 0.014
regulation of secretion GO:0051046 224 0.014
monosaccharide metabolic process GO:0005996 61 0.014
antigen receptor mediated signaling pathway GO:0050851 1 0.014
negative regulation of phosphorylation GO:0042326 57 0.013
ion transmembrane transport GO:0034220 365 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
response to radiation GO:0009314 137 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
positive regulation of transferase activity GO:0051347 81 0.013
axon development GO:0061564 96 0.013
protein dephosphorylation GO:0006470 38 0.013
oxoacid metabolic process GO:0043436 290 0.013
regulation of cell cycle GO:0051726 73 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
cell migration GO:0016477 197 0.013
organic substance catabolic process GO:1901575 316 0.013
hexose metabolic process GO:0019318 58 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
sensory organ development GO:0007423 74 0.013
gastrulation GO:0007369 2 0.013
camp metabolic process GO:0046058 63 0.013
single organism catabolic process GO:0044712 283 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
response to estrogen GO:0043627 232 0.013
cellular response to hormone stimulus GO:0032870 247 0.012
axis specification GO:0009798 4 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
regulation of neuron projection development GO:0010975 161 0.012
adult locomotory behavior GO:0008344 4 0.012
cellular cation homeostasis GO:0030003 180 0.012
cell cycle process GO:0022402 57 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
positive regulation of secretion GO:0051047 140 0.012
dna integrity checkpoint GO:0031570 2 0.012
circadian rhythm GO:0007623 88 0.012
head development GO:0060322 247 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regulation of protein localization GO:0032880 81 0.012
negative regulation of cell communication GO:0010648 158 0.012
single organism reproductive process GO:0044702 297 0.012
regulation of peptide transport GO:0090087 87 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
response to purine containing compound GO:0014074 126 0.012
cellular response to lipid GO:0071396 201 0.012
entrainment of circadian clock GO:0009649 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
response to decreased oxygen levels GO:0036293 237 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
protein autophosphorylation GO:0046777 66 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
protein processing GO:0016485 68 0.011
ion homeostasis GO:0050801 212 0.011
asymmetric stem cell division GO:0098722 2 0.011
somatic stem cell division GO:0048103 2 0.011
response to light stimulus GO:0009416 52 0.011
metal ion homeostasis GO:0055065 186 0.011
negative regulation of signal transduction GO:0009968 83 0.011
regulation of cell growth GO:0001558 85 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
vesicle mediated transport GO:0016192 181 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
glucose homeostasis GO:0042593 75 0.011
membrane organization GO:0061024 94 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
dna damage checkpoint GO:0000077 2 0.011
regulation of cell size GO:0008361 37 0.010
multi multicellular organism process GO:0044706 138 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
glycosaminoglycan biosynthetic process GO:0006024 4 0.010
regulation of proteolysis GO:0030162 66 0.010
regulation of blood circulation GO:1903522 110 0.010

Bad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.037
cancer DOID:162 0 0.034
organ system cancer DOID:0050686 0 0.032
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018
colon carcinoma DOID:1520 0 0.017
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
colorectal cancer DOID:9256 0 0.017
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010