Rattus norvegicus

21 known processes

Bckdhb

branched chain keto acid dehydrogenase E1, beta polypeptide

Bckdhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.712
Human
carboxylic acid catabolic process GO:0046395 49 0.506
Human
small molecule catabolic process GO:0044282 59 0.311
Human
cofactor metabolic process GO:0051186 95 0.297
cellular amino acid metabolic process GO:0006520 107 0.284
Human
organic substance catabolic process GO:1901575 316 0.226
Human
oxoacid metabolic process GO:0043436 290 0.226
Human
catabolic process GO:0009056 351 0.211
Human
coenzyme metabolic process GO:0006732 86 0.201
single organism catabolic process GO:0044712 283 0.195
Human
response to nutrient levels GO:0031667 370 0.179
organic acid metabolic process GO:0006082 292 0.165
Human
fatty acid metabolic process GO:0006631 99 0.142
response to extracellular stimulus GO:0009991 380 0.131
cellular component assembly GO:0022607 360 0.124
cellular catabolic process GO:0044248 295 0.109
Human
response to nutrient GO:0007584 248 0.106
protein complex biogenesis GO:0070271 263 0.096
protein homooligomerization GO:0051260 91 0.095
response to molecule of bacterial origin GO:0002237 194 0.093
cellular response to oxygen containing compound GO:1901701 386 0.089
monocarboxylic acid metabolic process GO:0032787 152 0.089
cellular component biogenesis GO:0044085 368 0.083
cellular amino acid catabolic process GO:0009063 21 0.082
Human
macromolecular complex assembly GO:0065003 273 0.069
protein complex assembly GO:0006461 263 0.066
regulation of multicellular organismal development GO:2000026 376 0.063
organic acid catabolic process GO:0016054 49 0.061
Human
regulation of protein metabolic process GO:0051246 289 0.059
cellular response to lipid GO:0071396 201 0.058
lipid metabolic process GO:0006629 283 0.056
regulation of neurogenesis GO:0050767 247 0.055
protein complex subunit organization GO:0071822 302 0.055
response to bacterium GO:0009617 200 0.054
branched chain amino acid catabolic process GO:0009083 4 0.054
Human
response to corticosteroid GO:0031960 235 0.052
transcription dna templated GO:0006351 377 0.051
sulfur compound metabolic process GO:0006790 70 0.050
organic acid biosynthetic process GO:0016053 83 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
organelle organization GO:0006996 266 0.048
fatty acid catabolic process GO:0009062 26 0.047
alpha amino acid catabolic process GO:1901606 20 0.046
macromolecule localization GO:0033036 252 0.046
developmental process involved in reproduction GO:0003006 159 0.045
generation of precursor metabolites and energy GO:0006091 62 0.045
response to lipopolysaccharide GO:0032496 191 0.045
protein oligomerization GO:0051259 191 0.044
cellular response to endogenous stimulus GO:0071495 377 0.043
reproductive process GO:0022414 372 0.043
carboxylic acid biosynthetic process GO:0046394 83 0.043
regulation of rna biosynthetic process GO:2001141 381 0.042
oxidation reduction process GO:0055114 304 0.042
Mouse
alpha amino acid metabolic process GO:1901605 71 0.041
response to metal ion GO:0010038 253 0.041
protein phosphorylation GO:0006468 345 0.041
response to peptide hormone GO:0043434 278 0.041
response to acid chemical GO:0001101 222 0.040
response to inorganic substance GO:0010035 377 0.040
rna metabolic process GO:0016070 406 0.040
single organism biosynthetic process GO:0044711 342 0.040
response to transition metal nanoparticle GO:1990267 122 0.039
hepaticobiliary system development GO:0061008 90 0.038
central nervous system development GO:0007417 311 0.038
response to oxygen levels GO:0070482 265 0.037
response to fatty acid GO:0070542 65 0.036
organonitrogen compound biosynthetic process GO:1901566 167 0.036
carbohydrate metabolic process GO:0005975 130 0.035
single organism reproductive process GO:0044702 297 0.034
response to hexose GO:0009746 144 0.034
response to glucocorticoid GO:0051384 223 0.034
regulation of transcription dna templated GO:0006355 374 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
rna biosynthetic process GO:0032774 380 0.032
head development GO:0060322 247 0.032
protein localization GO:0008104 191 0.032
macromolecular complex subunit organization GO:0043933 339 0.031
reproduction GO:0000003 245 0.031
regulation of nervous system development GO:0051960 264 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
response to hypoxia GO:0001666 231 0.030
organophosphate metabolic process GO:0019637 370 0.030
cellular response to hormone stimulus GO:0032870 247 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
reproductive system development GO:0061458 128 0.030
tricarboxylic acid metabolic process GO:0072350 10 0.030
regulation of catalytic activity GO:0050790 304 0.029
response to external biotic stimulus GO:0043207 221 0.029
response to biotic stimulus GO:0009607 226 0.029
regulation of cellular component organization GO:0051128 368 0.029
chemical homeostasis GO:0048878 292 0.029
regulation of rna metabolic process GO:0051252 391 0.029
gonad development GO:0008406 104 0.029
neuron differentiation GO:0030182 368 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
regulation of molecular function GO:0065009 398 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
Human
epithelium development GO:0060429 96 0.027
response to other organism GO:0051707 220 0.027
regulation of cell development GO:0060284 263 0.027
neuron development GO:0048666 286 0.027
cellular chemical homeostasis GO:0055082 247 0.026
cellular ion homeostasis GO:0006873 184 0.026
cellular amine metabolic process GO:0044106 38 0.026
response to monosaccharide GO:0034284 159 0.026
negative regulation of gene expression GO:0010629 199 0.026
regulation of apoptotic process GO:0042981 335 0.026
regulation of cell differentiation GO:0045595 320 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
establishment of protein localization GO:0045184 141 0.025
nucleic acid templated transcription GO:0097659 379 0.025
liver development GO:0001889 90 0.025
aging GO:0007568 241 0.024
protein targeting GO:0006605 61 0.024
cellular response to stress GO:0033554 269 0.024
nucleotide metabolic process GO:0009117 279 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
single organism organelle organization GO:1902589 180 0.024
negative regulation of metabolic process GO:0009892 331 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
nucleoside bisphosphate metabolic process GO:0033865 1 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
regulation of phosphorylation GO:0042325 248 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
cation transport GO:0006812 382 0.023
cell projection organization GO:0030030 302 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
cellular response to external stimulus GO:0071496 118 0.023
response to decreased oxygen levels GO:0036293 237 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
response to ethanol GO:0045471 162 0.022
regulation of ion transport GO:0043269 245 0.022
programmed cell death GO:0012501 392 0.022
response to temperature stimulus GO:0009266 94 0.021
neuron projection development GO:0031175 273 0.021
response to ketone GO:1901654 182 0.021
positive regulation of nervous system development GO:0051962 178 0.021
renal system development GO:0072001 67 0.021
regulation of neuron differentiation GO:0045664 208 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
protein homotetramerization GO:0051289 25 0.020
intracellular transport GO:0046907 185 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
cellular homeostasis GO:0019725 252 0.020
brain development GO:0007420 247 0.020
acyl coa metabolic process GO:0006637 28 0.020
ion homeostasis GO:0050801 212 0.020
cellular lipid metabolic process GO:0044255 208 0.020
cellular response to acid chemical GO:0071229 75 0.020
urogenital system development GO:0001655 78 0.020
response to carbohydrate GO:0009743 183 0.019
regulation of hormone levels GO:0010817 187 0.019
nucleoside metabolic process GO:0009116 179 0.019
positive regulation of developmental process GO:0051094 283 0.019
immune system process GO:0002376 204 0.019
response to peptide GO:1901652 292 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
tissue development GO:0009888 252 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
response to toxic substance GO:0009636 133 0.019
cellular component movement GO:0006928 248 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
kidney development GO:0001822 67 0.018
protein transport GO:0015031 132 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
metanephric tubule development GO:0072170 4 0.018
regulation of neuron projection development GO:0010975 161 0.018
cellular macromolecule localization GO:0070727 122 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.017
fatty acid beta oxidation GO:0006635 22 0.017
amine metabolic process GO:0009308 38 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
proteolysis GO:0006508 175 0.017
regulation of signal transduction GO:0009966 318 0.017
transmembrane transport GO:0055085 412 0.017
regulation of cell proliferation GO:0042127 359 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
regeneration GO:0031099 163 0.017
gland development GO:0048732 155 0.017
single organism cellular localization GO:1902580 102 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
intracellular signal transduction GO:0035556 314 0.017
anion transport GO:0006820 178 0.016
protein processing GO:0016485 68 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of programmed cell death GO:0043067 341 0.016
protein maturation GO:0051604 68 0.016
response to vitamin GO:0033273 131 0.016
cellular cation homeostasis GO:0030003 180 0.016
secretion GO:0046903 307 0.016
development of primary sexual characteristics GO:0045137 107 0.016
positive regulation of transport GO:0051050 245 0.016
negative regulation of cell death GO:0060548 229 0.016
negative regulation of signaling GO:0023057 157 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
apoptotic process GO:0006915 381 0.015
metal ion homeostasis GO:0055065 186 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
reproductive structure development GO:0048608 128 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular ketone metabolic process GO:0042180 51 0.015
vesicle mediated transport GO:0016192 181 0.015
ion transmembrane transport GO:0034220 365 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
positive regulation of molecular function GO:0044093 230 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
cell cell signaling GO:0007267 335 0.014
negative regulation of cell communication GO:0010648 158 0.014
lipid modification GO:0030258 52 0.014
cellular response to nutrient levels GO:0031669 60 0.014
circulatory system process GO:0003013 183 0.014
neurological system process GO:0050877 219 0.014
homeostatic process GO:0042592 331 0.014
cytoplasmic transport GO:0016482 115 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
lipid catabolic process GO:0016042 46 0.014
cation homeostasis GO:0055080 195 0.014
response to starvation GO:0042594 59 0.014
nephron tubule development GO:0072080 12 0.013
positive regulation of cell death GO:0010942 184 0.013
protein tetramerization GO:0051262 38 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
leydig cell differentiation GO:0033327 8 0.013
branched chain amino acid metabolic process GO:0009081 4 0.013
Human
multi organism reproductive process GO:0044703 262 0.013
multicellular organismal signaling GO:0035637 44 0.013
signal release GO:0023061 145 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
positive regulation of gene expression GO:0010628 244 0.013
regulation of cellular localization GO:0060341 263 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
response to insulin GO:0032868 133 0.013
serine family amino acid metabolic process GO:0009069 12 0.012
hormone metabolic process GO:0042445 69 0.012
response to mechanical stimulus GO:0009612 134 0.012
metanephric epithelium development GO:0072207 4 0.012
heterocycle catabolic process GO:0046700 167 0.012
organic anion transport GO:0015711 132 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
regulation of membrane potential GO:0042391 110 0.012
response to growth factor GO:0070848 189 0.012
defense response GO:0006952 194 0.012
regulation of immune system process GO:0002682 123 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
small molecule biosynthetic process GO:0044283 124 0.012
blood circulation GO:0008015 183 0.012
cellular response to oxygen levels GO:0071453 60 0.012
response to estradiol GO:0032355 164 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cell motility GO:0048870 202 0.012
behavior GO:0007610 205 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
regulation of system process GO:0044057 208 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of metal ion transport GO:0010959 118 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
glycosyl compound metabolic process GO:1901657 182 0.011
locomotion GO:0040011 237 0.011
steroid metabolic process GO:0008202 73 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of catabolic process GO:0009894 113 0.011
response to glucose GO:0009749 136 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
serine family amino acid catabolic process GO:0009071 3 0.011
cell cycle GO:0007049 101 0.011
regulation of calcium ion transport GO:0051924 77 0.011
positive regulation of cell communication GO:0010647 271 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of signaling GO:0023056 270 0.011
localization of cell GO:0051674 202 0.011
positive regulation of ion transport GO:0043270 94 0.011
calcium ion homeostasis GO:0055074 162 0.011
organophosphate catabolic process GO:0046434 148 0.011
spermatogenesis GO:0007283 99 0.011
gliogenesis GO:0042063 93 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
male gonad development GO:0008584 59 0.011
maintenance of location GO:0051235 17 0.011
male gamete generation GO:0048232 99 0.011
secretion by cell GO:0032940 248 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
response to cytokine GO:0034097 215 0.011
protein import GO:0017038 37 0.011
porphyrin containing compound metabolic process GO:0006778 8 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
cellular protein localization GO:0034613 122 0.010
regulation of homeostatic process GO:0032844 101 0.010
gastrulation GO:0007369 2 0.010
response to alkaloid GO:0043279 132 0.010
heart morphogenesis GO:0003007 3 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
embryonic pattern specification GO:0009880 1 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
immune response GO:0006955 104 0.010
regulation of transferase activity GO:0051338 123 0.010
anterior posterior pattern specification GO:0009952 1 0.010
fatty acid oxidation GO:0019395 29 0.010
negative regulation of signal transduction GO:0009968 83 0.010
metal ion transport GO:0030001 289 0.010

Bckdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.131
Human
inherited metabolic disorder DOID:655 0 0.131
Human
amino acid metabolic disorder DOID:9252 0 0.075
Human
organic acidemia DOID:0060159 0 0.066
Human
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014