Rattus norvegicus

25 known processes

Birc3

baculoviral IAP repeat-containing 3

(Aliases: MGC93416,Birc2,IAP1)

Birc3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.153
response to tumor necrosis factor GO:0034612 56 0.149
cellular response to cytokine stimulus GO:0071345 127 0.137
immune response GO:0006955 104 0.120
jak stat cascade GO:0007259 26 0.110
response to extracellular stimulus GO:0009991 380 0.103
regulation of signal transduction GO:0009966 318 0.102
intracellular signal transduction GO:0035556 314 0.094
response to inorganic substance GO:0010035 377 0.088
response to nutrient levels GO:0031667 370 0.087
regulation of protein metabolic process GO:0051246 289 0.085
Human
cellular response to tumor necrosis factor GO:0071356 46 0.084
reproductive process GO:0022414 372 0.082
regulation of phosphate metabolic process GO:0019220 349 0.081
positive regulation of biosynthetic process GO:0009891 319 0.079
defense response GO:0006952 194 0.078
protein phosphorylation GO:0006468 345 0.078
cellular amino acid metabolic process GO:0006520 107 0.074
response to bacterium GO:0009617 200 0.073
organic acid metabolic process GO:0006082 292 0.071
single organism reproductive process GO:0044702 297 0.066
response to vitamin GO:0033273 131 0.065
negative regulation of response to stimulus GO:0048585 155 0.065
angiogenesis GO:0001525 53 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.061
cellular response to molecule of bacterial origin GO:0071219 56 0.059
homeostatic process GO:0042592 331 0.057
response to acid chemical GO:0001101 222 0.057
positive regulation of phosphorylation GO:0042327 177 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.056
regulation of intracellular signal transduction GO:1902531 218 0.055
response to organophosphorus GO:0046683 102 0.055
Rat
cytokine mediated signaling pathway GO:0019221 43 0.054
negative regulation of cellular metabolic process GO:0031324 281 0.053
cell projection organization GO:0030030 302 0.052
protein transport GO:0015031 132 0.052
regulation of phosphorylation GO:0042325 248 0.051
cellular response to oxygen containing compound GO:1901701 386 0.051
carboxylic acid metabolic process GO:0019752 289 0.050
negative regulation of metabolic process GO:0009892 331 0.049
immune system process GO:0002376 204 0.049
acute phase response GO:0006953 20 0.049
cellular amine metabolic process GO:0044106 38 0.047
response to biotic stimulus GO:0009607 226 0.046
cellular response to lipopolysaccharide GO:0071222 55 0.046
regulation of rna metabolic process GO:0051252 391 0.046
regulation of cellular extravasation GO:0002691 2 0.045
aging GO:0007568 241 0.045
response to cytokine GO:0034097 215 0.045
positive regulation of cell proliferation GO:0008284 249 0.045
cellular response to lipid GO:0071396 201 0.045
positive regulation of response to stimulus GO:0048584 285 0.045
macromolecular complex subunit organization GO:0043933 339 0.044
cellular chemical homeostasis GO:0055082 247 0.044
protein oligomerization GO:0051259 191 0.044
regulation of molecular function GO:0065009 398 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
response to lipopolysaccharide GO:0032496 191 0.041
multi organism reproductive process GO:0044703 262 0.041
cellular amide metabolic process GO:0043603 44 0.041
cellular response to stress GO:0033554 269 0.041
regulation of immune response GO:0050776 55 0.040
oxoacid metabolic process GO:0043436 290 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
macromolecule localization GO:0033036 252 0.038
positive regulation of behavior GO:0048520 38 0.038
response to ketone GO:1901654 182 0.037
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.037
innate immune response GO:0045087 35 0.037
cellular component biogenesis GO:0044085 368 0.037
nitrogen compound transport GO:0071705 229 0.037
response to metal ion GO:0010038 253 0.037
cellular response to biotic stimulus GO:0071216 59 0.036
divalent inorganic cation homeostasis GO:0072507 165 0.036
positive regulation of mast cell chemotaxis GO:0060754 1 0.036
apoptotic process GO:0006915 381 0.036
Human Rat
response to hydrogen peroxide GO:0042542 89 0.035
cellular ketone metabolic process GO:0042180 51 0.035
positive regulation of immune response GO:0050778 42 0.035
response to decreased oxygen levels GO:0036293 237 0.035
Rat
reproduction GO:0000003 245 0.035
regulation of neuron differentiation GO:0045664 208 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.035
Human
macromolecular complex assembly GO:0065003 273 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
response to transition metal nanoparticle GO:1990267 122 0.034
reactive oxygen species metabolic process GO:0072593 37 0.034
positive regulation of cell migration GO:0030335 96 0.034
neuron differentiation GO:0030182 368 0.034
regulation of locomotion GO:0040012 148 0.034
response to oxygen levels GO:0070482 265 0.033
Rat
regulation of cellular localization GO:0060341 263 0.033
mapk cascade GO:0000165 140 0.032
establishment of protein localization GO:0045184 141 0.032
transcription dna templated GO:0006351 377 0.032
positive regulation of cellular component organization GO:0051130 200 0.031
cellular cation homeostasis GO:0030003 180 0.031
reactive nitrogen species metabolic process GO:2001057 1 0.031
regulation of cell projection organization GO:0031344 175 0.031
anatomical structure morphogenesis GO:0009653 298 0.030
amine metabolic process GO:0009308 38 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
positive regulation of response to external stimulus GO:0032103 51 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
positive regulation of cellular component movement GO:0051272 102 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
cellular response to oxidative stress GO:0034599 76 0.029
response to hypoxia GO:0001666 231 0.029
Rat
lipid metabolic process GO:0006629 283 0.029
regulation of transcription dna templated GO:0006355 374 0.029
positive regulation of neurogenesis GO:0050769 165 0.028
regulation of t cell migration GO:2000404 1 0.028
nucleic acid templated transcription GO:0097659 379 0.028
positive regulation of signaling GO:0023056 270 0.028
cellular component assembly GO:0022607 360 0.028
cell cell signaling GO:0007267 335 0.028
regulation of t cell chemotaxis GO:0010819 1 0.028
positive regulation of cell development GO:0010720 176 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.027
protein complex biogenesis GO:0070271 263 0.027
regulation of protein modification process GO:0031399 194 0.027
Human
cellular homeostasis GO:0019725 252 0.027
response to amino acid GO:0043200 75 0.027
mast cell migration GO:0097531 4 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
secretion GO:0046903 307 0.026
regulation of mapk cascade GO:0043408 116 0.026
response to external biotic stimulus GO:0043207 221 0.026
cardiovascular system development GO:0072358 134 0.026
regulation of cell development GO:0060284 263 0.026
regulation of hormone levels GO:0010817 187 0.026
regulation of neurogenesis GO:0050767 247 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
cellular component movement GO:0006928 248 0.026
rna biosynthetic process GO:0032774 380 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
leukocyte migration GO:0050900 38 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
positive regulation of nervous system development GO:0051962 178 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
protein localization GO:0008104 191 0.025
regulation of catalytic activity GO:0050790 304 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.024
response to radiation GO:0009314 137 0.024
peptide metabolic process GO:0006518 32 0.024
negative regulation of signaling GO:0023057 157 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of immune system process GO:0002682 123 0.024
cellular modified amino acid metabolic process GO:0006575 61 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
cell migration GO:0016477 197 0.024
peptide transport GO:0015833 97 0.024
response to ionizing radiation GO:0010212 59 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.023
regulation of ion transport GO:0043269 245 0.023
response to temperature stimulus GO:0009266 94 0.023
response to wounding GO:0009611 254 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
single organism biosynthetic process GO:0044711 342 0.022
regulation of programmed cell death GO:0043067 341 0.022
Human Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
regulation of protein transport GO:0051223 68 0.022
oxidation reduction process GO:0055114 304 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
cytoplasmic transport GO:0016482 115 0.022
response to reactive oxygen species GO:0000302 120 0.022
organ regeneration GO:0031100 101 0.022
regeneration GO:0031099 163 0.021
cellular response to interleukin 1 GO:0071347 37 0.021
positive regulation of leukocyte migration GO:0002687 21 0.021
programmed cell death GO:0012501 392 0.021
Human Rat
chemical homeostasis GO:0048878 292 0.021
regulation of cellular component organization GO:0051128 368 0.021
regulation of defense response GO:0031347 68 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
d amino acid transport GO:0042940 1 0.021
response to corticosteroid GO:0031960 235 0.020
mesoderm development GO:0007498 2 0.020
regulation of kinase activity GO:0043549 117 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to interleukin 1 GO:0070555 55 0.020
negative regulation of cell death GO:0060548 229 0.020
Rat
alpha amino acid metabolic process GO:1901605 71 0.020
response to other organism GO:0051707 220 0.020
lymphocyte migration GO:0072676 3 0.020
regulation of jak stat cascade GO:0046425 21 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
ion homeostasis GO:0050801 212 0.020
cell motility GO:0048870 202 0.019
cytokine biosynthetic process GO:0042089 3 0.019
cation transport GO:0006812 382 0.019
protein complex subunit organization GO:0071822 302 0.019
regulation of apoptotic process GO:0042981 335 0.019
Human Rat
regulation of lymphocyte chemotaxis GO:1901623 1 0.019
peptidyl amino acid modification GO:0018193 126 0.019
calcium ion homeostasis GO:0055074 162 0.019
response to growth factor GO:0070848 189 0.019
alcohol metabolic process GO:0006066 77 0.019
regulation of cell migration GO:0030334 128 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
head development GO:0060322 247 0.019
response to peptide hormone GO:0043434 278 0.019
regulation of neuron death GO:1901214 115 0.018
Rat
wound healing GO:0042060 122 0.018
positive regulation of signal transduction GO:0009967 175 0.018
circulatory system development GO:0072359 134 0.018
multi multicellular organism process GO:0044706 138 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
reproductive system development GO:0061458 128 0.018
amide transport GO:0042886 105 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of lymphocyte migration GO:2000403 1 0.018
catabolic process GO:0009056 351 0.018
positive regulation of mapk cascade GO:0043410 92 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
negative regulation of cell communication GO:0010648 158 0.017
central nervous system development GO:0007417 311 0.017
organophosphate metabolic process GO:0019637 370 0.017
maintenance of location GO:0051235 17 0.017
protein homooligomerization GO:0051260 91 0.017
lymphocyte chemotaxis GO:0048247 3 0.017
positive regulation of cell motility GO:2000147 97 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
gonad development GO:0008406 104 0.017
response to camp GO:0051591 91 0.017
Rat
female pregnancy GO:0007565 122 0.017
positive regulation of immune system process GO:0002684 90 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
anion transport GO:0006820 178 0.016
interleukin 12 production GO:0032615 3 0.016
jnk cascade GO:0007254 28 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
regulation of jnk cascade GO:0046328 19 0.016
amide biosynthetic process GO:0043604 10 0.016
purine containing compound metabolic process GO:0072521 253 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
regulation of protein localization GO:0032880 81 0.016
hormone secretion GO:0046879 115 0.016
positive regulation of jnk cascade GO:0046330 13 0.016
cell adhesion GO:0007155 110 0.016
protein complex assembly GO:0006461 263 0.016
regulation of cell motility GO:2000145 131 0.015
response to heat GO:0009408 60 0.015
neuron projection development GO:0031175 273 0.015
single organism organelle organization GO:1902589 180 0.015
response to glucocorticoid GO:0051384 223 0.015
metal ion homeostasis GO:0055065 186 0.015
response to monosaccharide GO:0034284 159 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
lipid storage GO:0019915 1 0.015
myeloid leukocyte migration GO:0097529 20 0.015
response to carbohydrate GO:0009743 183 0.015
rna metabolic process GO:0016070 406 0.015
gland development GO:0048732 155 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
cellular response to peptide GO:1901653 133 0.015
positive regulation of t cell migration GO:2000406 1 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
response to interleukin 13 GO:0035962 3 0.014
response to estrogen GO:0043627 232 0.014
brain development GO:0007420 247 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
regulation of cytokine biosynthetic process GO:0042035 3 0.014
regulation of metal ion transport GO:0010959 118 0.014
negative regulation of molecular function GO:0044092 133 0.014
response to alkaloid GO:0043279 132 0.014
cell chemotaxis GO:0060326 31 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
protein heterooligomerization GO:0051291 89 0.014
blood vessel development GO:0001568 69 0.014
vitamin d biosynthetic process GO:0042368 2 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
Rat
positive regulation of jak stat cascade GO:0046427 19 0.014
neutrophil migration GO:1990266 12 0.014
sexual reproduction GO:0019953 148 0.014
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
immunoglobulin secretion GO:0048305 1 0.014
response to mechanical stimulus GO:0009612 134 0.014
neuron development GO:0048666 286 0.014
response to purine containing compound GO:0014074 126 0.014
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
ras protein signal transduction GO:0007265 29 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to amine GO:0014075 46 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
positive regulation of isotype switching GO:0045830 1 0.013
single organism cellular localization GO:1902580 102 0.013
positive regulation of locomotion GO:0040017 102 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
metal ion transport GO:0030001 289 0.013
necroptotic process GO:0070266 2 0.013
Human
response to estradiol GO:0032355 164 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
Rat
positive regulation of gene expression GO:0010628 244 0.013
stress activated mapk cascade GO:0051403 35 0.013
stress activated protein kinase signaling cascade GO:0031098 37 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
monosaccharide metabolic process GO:0005996 61 0.013
interleukin 1 biosynthetic process GO:0042222 1 0.013
gastrulation GO:0007369 2 0.013
hormone transport GO:0009914 121 0.013
locomotion GO:0040011 237 0.012
regulation of cell proliferation GO:0042127 359 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
proteolysis GO:0006508 175 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
sequestering of metal ion GO:0051238 9 0.012
organic acid transport GO:0015849 116 0.012
regulation of lymphocyte migration GO:2000401 1 0.012
i kappab kinase nf kappab signaling GO:0007249 19 0.012
response to insulin GO:0032868 133 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of cellular component movement GO:0051270 150 0.012
acute inflammatory response GO:0002526 58 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
response to peptide GO:1901652 292 0.012
formation of primary germ layer GO:0001704 1 0.012
single organism membrane organization GO:0044802 74 0.012
negative regulation of viral process GO:0048525 4 0.012
regulation of system process GO:0044057 208 0.012
membrane organization GO:0061024 94 0.012
small molecule biosynthetic process GO:0044283 124 0.012
cellular catabolic process GO:0044248 295 0.012
blood vessel morphogenesis GO:0048514 58 0.012
t cell migration GO:0072678 2 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
vitamin d metabolic process GO:0042359 4 0.011
reproductive structure development GO:0048608 128 0.011
insulin receptor signaling pathway GO:0008286 24 0.011
multicellular organism reproduction GO:0032504 233 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
cell activation GO:0001775 97 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of gene expression GO:0010629 199 0.011
biological adhesion GO:0022610 110 0.011
response to virus GO:0009615 17 0.011
cytokine production GO:0001816 61 0.011
response to vitamin d GO:0033280 34 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
steroid metabolic process GO:0008202 73 0.011
cellular protein localization GO:0034613 122 0.011
t cell receptor signaling pathway GO:0050852 1 0.011
salivary gland morphogenesis GO:0007435 1 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
Human
multicellular organismal signaling GO:0035637 44 0.011
cytoplasmic sequestering of protein GO:0051220 3 0.011
divalent inorganic cation transport GO:0072511 134 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
intracellular transport GO:0046907 185 0.011
striated muscle tissue development GO:0014706 58 0.011
cellular response to lipoteichoic acid GO:0071223 1 0.011
positive regulation of humoral immune response GO:0002922 2 0.011
positive regulation of developmental process GO:0051094 283 0.011
positive regulation of cell death GO:0010942 184 0.010
regulation of intracellular transport GO:0032386 65 0.010
neurological system process GO:0050877 219 0.010
sex differentiation GO:0007548 113 0.010
positive regulation of chemotaxis GO:0050921 23 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
defense response to other organism GO:0098542 17 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
response to glucose GO:0009749 136 0.010
development of primary sexual characteristics GO:0045137 107 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
rna localization GO:0006403 4 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010

Birc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.013