Rattus norvegicus

0 known processes

Blk

B lymphoid tyrosine kinase

(Aliases: MGC112647)

Blk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.065
regulation of transcription dna templated GO:0006355 374 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.058
negative regulation of cellular metabolic process GO:0031324 281 0.055
positive regulation of gene expression GO:0010628 244 0.054
rna metabolic process GO:0016070 406 0.054
nucleic acid templated transcription GO:0097659 379 0.053
positive regulation of response to stimulus GO:0048584 285 0.051
Human
secretion by cell GO:0032940 248 0.051
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.051
regulation of rna metabolic process GO:0051252 391 0.046
positive regulation of rna metabolic process GO:0051254 203 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
nucleoside phosphate metabolic process GO:0006753 283 0.045
glycosyl compound metabolic process GO:1901657 182 0.044
response to extracellular stimulus GO:0009991 380 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.041
catabolic process GO:0009056 351 0.040
response to bacterium GO:0009617 200 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.039
response to hypoxia GO:0001666 231 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.039
transcription dna templated GO:0006351 377 0.038
response to lipopolysaccharide GO:0032496 191 0.038
oxoacid metabolic process GO:0043436 290 0.038
nucleotide metabolic process GO:0009117 279 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
negative regulation of metabolic process GO:0009892 331 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of cellular component organization GO:0051128 368 0.036
single organism catabolic process GO:0044712 283 0.035
cellular catabolic process GO:0044248 295 0.035
homeostatic process GO:0042592 331 0.034
organelle organization GO:0006996 266 0.034
rna biosynthetic process GO:0032774 380 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
myeloid leukocyte activation GO:0002274 36 0.033
Rat
purine nucleotide metabolic process GO:0006163 229 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
regulation of molecular function GO:0065009 398 0.032
cellular ion homeostasis GO:0006873 184 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
cell projection organization GO:0030030 302 0.031
purine containing compound metabolic process GO:0072521 253 0.031
ion homeostasis GO:0050801 212 0.031
purine ribonucleotide catabolic process GO:0009154 136 0.031
response to biotic stimulus GO:0009607 226 0.030
Rat
regulation of catalytic activity GO:0050790 304 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
cellular chemical homeostasis GO:0055082 247 0.029
regulation of cell proliferation GO:0042127 359 0.029
positive regulation of molecular function GO:0044093 230 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
cellular homeostasis GO:0019725 252 0.028
regulation of response to external stimulus GO:0032101 106 0.028
cellular response to stress GO:0033554 269 0.027
Rat
heterocycle catabolic process GO:0046700 167 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
cellular component assembly GO:0022607 360 0.027
response to tumor cell GO:0002347 4 0.027
response to nutrient levels GO:0031667 370 0.027
neuron differentiation GO:0030182 368 0.026
organic acid metabolic process GO:0006082 292 0.026
positive regulation of humoral immune response GO:0002922 2 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
tissue development GO:0009888 252 0.025
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.025
macromolecular complex assembly GO:0065003 273 0.025
vesicle mediated transport GO:0016192 181 0.025
Rat
response to molecule of bacterial origin GO:0002237 194 0.025
purine containing compound catabolic process GO:0072523 138 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of cell development GO:0060284 263 0.024
cell activation GO:0001775 97 0.024
Rat
ribonucleotide metabolic process GO:0009259 231 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cellular cation homeostasis GO:0030003 180 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
response to wounding GO:0009611 254 0.022
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
leukocyte activation GO:0045321 76 0.022
Rat
single organism organelle organization GO:1902589 180 0.022
response to oxidative stress GO:0006979 186 0.022
Rat
negative regulation of biosynthetic process GO:0009890 168 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
cation transport GO:0006812 382 0.021
Rat
t cell activation GO:0042110 29 0.021
chromosome segregation GO:0007059 2 0.021
regulation of apoptotic process GO:0042981 335 0.021
response to nutrient GO:0007584 248 0.020
cellular component biogenesis GO:0044085 368 0.020
protein complex subunit organization GO:0071822 302 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
chemical homeostasis GO:0048878 292 0.020
aromatic compound catabolic process GO:0019439 168 0.020
response to purine containing compound GO:0014074 126 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
neuron projection development GO:0031175 273 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.019
positive regulation of immune system process GO:0002684 90 0.019
Human
programmed cell death GO:0012501 392 0.019
regulation of cell differentiation GO:0045595 320 0.019
proteolysis GO:0006508 175 0.019
apoptotic process GO:0006915 381 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of hydrolase activity GO:0051336 143 0.019
nucleoside metabolic process GO:0009116 179 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
protein complex assembly GO:0006461 263 0.019
neuron development GO:0048666 286 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
response to oxygen levels GO:0070482 265 0.019
organic substance catabolic process GO:1901575 316 0.018
lipid metabolic process GO:0006629 283 0.018
inflammatory response GO:0006954 150 0.018
Rat
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
negative regulation of gene expression GO:0010629 199 0.018
secretion GO:0046903 307 0.018
Human Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
cell cell signaling GO:0007267 335 0.017
Human Rat
cellular amine metabolic process GO:0044106 38 0.017
response to external biotic stimulus GO:0043207 221 0.017
Rat
cellular metal ion homeostasis GO:0006875 172 0.017
intracellular signal transduction GO:0035556 314 0.017
endocytosis GO:0006897 84 0.017
protein complex biogenesis GO:0070271 263 0.017
regulation of programmed cell death GO:0043067 341 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
immunoglobulin mediated immune response GO:0016064 4 0.017
cellular calcium ion homeostasis GO:0006874 160 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
regulation of membrane potential GO:0042391 110 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
cell migration GO:0016477 197 0.016
ras protein signal transduction GO:0007265 29 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
response to reactive oxygen species GO:0000302 120 0.016
Rat
single organism intracellular transport GO:1902582 166 0.016
Rat
urogenital system development GO:0001655 78 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
defense response GO:0006952 194 0.016
Rat
regulation of catabolic process GO:0009894 113 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
metal ion transport GO:0030001 289 0.015
regulation of immune system process GO:0002682 123 0.015
Human
regulation of cellular amine metabolic process GO:0033238 8 0.015
cation homeostasis GO:0055080 195 0.015
regulation of response to wounding GO:1903034 69 0.015
regulation of phosphorylation GO:0042325 248 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of neuron differentiation GO:0045664 208 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of lipid kinase activity GO:0090218 2 0.015
metal ion homeostasis GO:0055065 186 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.014
protein processing GO:0016485 68 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
cell part morphogenesis GO:0032990 123 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
regulation of immune response GO:0050776 55 0.014
Human
negative regulation of cell cycle phase transition GO:1901988 4 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
gtp metabolic process GO:0046039 72 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
cytoplasmic transport GO:0016482 115 0.014
protein maturation GO:0051604 68 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
Rat
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of secretion by cell GO:1903530 208 0.013
Human
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
amine metabolic process GO:0009308 38 0.013
regulation of regulatory t cell differentiation GO:0045589 2 0.013
regulation of nervous system development GO:0051960 264 0.013
cellular response to oxygen containing compound GO:1901701 386 0.013
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
response to peptide GO:1901652 292 0.013
central nervous system development GO:0007417 311 0.013
circulatory system process GO:0003013 183 0.013
response to metal ion GO:0010038 253 0.013
regulation of ion transport GO:0043269 245 0.013
immune system process GO:0002376 204 0.013
Human Rat
response to mechanical stimulus GO:0009612 134 0.013
response to other organism GO:0051707 220 0.013
Rat
gtp catabolic process GO:0006184 71 0.013
regulation of protein metabolic process GO:0051246 289 0.013
positive regulation of transport GO:0051050 245 0.013
Human
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
cellular response to lipid GO:0071396 201 0.012
positive regulation of cell death GO:0010942 184 0.012
negative regulation of molecular function GO:0044092 133 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
membrane organization GO:0061024 94 0.012
positive regulation of immune response GO:0050778 42 0.012
Human
calcium ion homeostasis GO:0055074 162 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
axis specification GO:0009798 4 0.012
nucleotide catabolic process GO:0009166 139 0.012
transmembrane transport GO:0055085 412 0.012
establishment of protein localization GO:0045184 141 0.012
positive regulation of developmental process GO:0051094 283 0.012
response to decreased oxygen levels GO:0036293 237 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
positive regulation of cell development GO:0010720 176 0.012
organ morphogenesis GO:0009887 75 0.012
organophosphate catabolic process GO:0046434 148 0.012
muscle system process GO:0003012 115 0.012
spindle organization GO:0007051 2 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
protein autophosphorylation GO:0046777 66 0.012
Rat
tube formation GO:0035148 3 0.012
cellular component movement GO:0006928 248 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of signal transduction GO:0009966 318 0.011
positive regulation of b cell mediated immunity GO:0002714 2 0.011
multicellular organism reproduction GO:0032504 233 0.011
reproductive process GO:0022414 372 0.011
hormone secretion GO:0046879 115 0.011
Human Rat
regulation of secretion GO:0051046 224 0.011
Human
single organism cellular localization GO:1902580 102 0.011
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to growth factor GO:0070848 189 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
regulation of cell projection organization GO:0031344 175 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
positive regulation of regulatory t cell differentiation GO:0045591 2 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
protein homooligomerization GO:0051260 91 0.011
response to carbohydrate GO:0009743 183 0.011
cellular response to oxygen levels GO:0071453 60 0.011
cellular component morphogenesis GO:0032989 155 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of system process GO:0044057 208 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cell adhesion GO:0007155 110 0.011
salivary gland development GO:0007431 3 0.011
rna localization GO:0006403 4 0.011
ncrna processing GO:0034470 3 0.011
dna metabolic process GO:0006259 96 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
heart morphogenesis GO:0003007 3 0.010
regulation of gtpase activity GO:0043087 57 0.010
multicellular organismal homeostasis GO:0048871 49 0.010
calcium ion transport GO:0006816 131 0.010
cellular response to molecule of bacterial origin GO:0071219 56 0.010
organophosphate metabolic process GO:0019637 370 0.010
liver development GO:0001889 90 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
intracellular transport GO:0046907 185 0.010
Rat
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
positive regulation of signaling GO:0023056 270 0.010
Human
reproduction GO:0000003 245 0.010
fatty acid metabolic process GO:0006631 99 0.010

Blk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
disease of cellular proliferation DOID:14566 0 0.011