Rattus norvegicus

0 known processes

Brd3

bromodomain containing 3

Brd3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.230
regulation of rna metabolic process GO:0051252 391 0.156
rna biosynthetic process GO:0032774 380 0.143
regulation of nucleic acid templated transcription GO:1903506 380 0.093
negative regulation of rna metabolic process GO:0051253 123 0.087
transcription dna templated GO:0006351 377 0.086
regulation of transcription dna templated GO:0006355 374 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.080
positive regulation of phosphorus metabolic process GO:0010562 262 0.077
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.076
negative regulation of cellular metabolic process GO:0031324 281 0.072
regulation of cell differentiation GO:0045595 320 0.066
negative regulation of cellular biosynthetic process GO:0031327 161 0.064
positive regulation of rna biosynthetic process GO:1902680 197 0.063
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.060
positive regulation of gene expression GO:0010628 244 0.056
negative regulation of biosynthetic process GO:0009890 168 0.055
nucleic acid templated transcription GO:0097659 379 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.050
intracellular signal transduction GO:0035556 314 0.050
positive regulation of rna metabolic process GO:0051254 203 0.049
positive regulation of transcription dna templated GO:0045893 197 0.042
negative regulation of metabolic process GO:0009892 331 0.041
peptidyl amino acid modification GO:0018193 126 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
single organism organelle organization GO:1902589 180 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of neuron projection development GO:0010975 161 0.036
positive regulation of developmental process GO:0051094 283 0.036
positive regulation of molecular function GO:0044093 230 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
regulation of rna biosynthetic process GO:2001141 381 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.034
regulation of signal transduction GO:0009966 318 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
regulation of catalytic activity GO:0050790 304 0.033
cellular response to lipid GO:0071396 201 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
rna metabolic process GO:0016070 406 0.032
cell cell signaling GO:0007267 335 0.032
negative regulation of gene expression GO:0010629 199 0.031
response to fungicide GO:0060992 20 0.031
cellular amine metabolic process GO:0044106 38 0.030
regulation of protein kinase activity GO:0045859 105 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
catabolic process GO:0009056 351 0.030
regulation of apoptotic process GO:0042981 335 0.030
regulation of phosphorylation GO:0042325 248 0.030
regulation of neuron differentiation GO:0045664 208 0.029
organelle organization GO:0006996 266 0.029
Rat
regulation of multicellular organismal development GO:2000026 376 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
brain development GO:0007420 247 0.028
neuron projection development GO:0031175 273 0.028
regulation of kinase activity GO:0043549 117 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of cellular component organization GO:0051128 368 0.028
response to acid chemical GO:0001101 222 0.028
heterocycle catabolic process GO:0046700 167 0.027
cellular chemical homeostasis GO:0055082 247 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of molecular function GO:0065009 398 0.027
response to extracellular stimulus GO:0009991 380 0.027
retinoic acid receptor signaling pathway GO:0048384 7 0.027
macromolecular complex subunit organization GO:0043933 339 0.026
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.026
amine metabolic process GO:0009308 38 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
oxoacid metabolic process GO:0043436 290 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
neuron differentiation GO:0030182 368 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
regulation of programmed cell death GO:0043067 341 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
neurological system process GO:0050877 219 0.024
regulation of cell development GO:0060284 263 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
response to ethanol GO:0045471 162 0.024
single organism biosynthetic process GO:0044711 342 0.024
response to growth factor GO:0070848 189 0.024
protein phosphorylation GO:0006468 345 0.024
positive regulation of cell development GO:0010720 176 0.024
cell projection organization GO:0030030 302 0.023
regulation of cell projection organization GO:0031344 175 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
neuron death GO:0070997 127 0.023
organophosphate metabolic process GO:0019637 370 0.023
negative regulation of cell communication GO:0010648 158 0.023
histone methylation GO:0016571 3 0.023
regulation of nervous system development GO:0051960 264 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
positive regulation of signal transduction GO:0009967 175 0.022
negative regulation of protein import into nucleus translocation GO:0033159 1 0.022
positive regulation of phosphorylation GO:0042327 177 0.021
regulation of neurogenesis GO:0050767 247 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
locomotion GO:0040011 237 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
motor neuron axon guidance GO:0008045 1 0.021
regulation of protein modification process GO:0031399 194 0.021
positive regulation of nervous system development GO:0051962 178 0.020
organic substance catabolic process GO:1901575 316 0.020
protein complex assembly GO:0006461 263 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
mapk cascade GO:0000165 140 0.020
response to nutrient levels GO:0031667 370 0.020
regulation of cellular localization GO:0060341 263 0.020
nucleotide metabolic process GO:0009117 279 0.020
regulation of cell proliferation GO:0042127 359 0.019
anterior posterior pattern specification GO:0009952 1 0.019
positive regulation of protein kinase activity GO:0045860 73 0.019
central nervous system development GO:0007417 311 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
organic acid metabolic process GO:0006082 292 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
protein complex biogenesis GO:0070271 263 0.019
tissue development GO:0009888 252 0.019
cellular ketone metabolic process GO:0042180 51 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
cellular component biogenesis GO:0044085 368 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
positive regulation of cell communication GO:0010647 271 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
apoptotic process GO:0006915 381 0.018
chromatin modification GO:0016568 33 0.018
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of rab protein signal transduction GO:0032483 3 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
defense response GO:0006952 194 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
cation homeostasis GO:0055080 195 0.017
circadian regulation of gene expression GO:0032922 3 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
homeostatic process GO:0042592 331 0.017
chromosome organization GO:0051276 36 0.017
Rat
response to estrogen GO:0043627 232 0.017
synaptic transmission GO:0007268 235 0.017
chromatin organization GO:0006325 34 0.017
Rat
regulation of protein phosphorylation GO:0001932 183 0.017
negative regulation of transport GO:0051051 136 0.017
histone modification GO:0016570 30 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
positive regulation of neuron differentiation GO:0045666 126 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.016
cellular homeostasis GO:0019725 252 0.016
establishment of tissue polarity GO:0007164 2 0.016
protein localization GO:0008104 191 0.016
carbohydrate metabolic process GO:0005975 130 0.016
chemical homeostasis GO:0048878 292 0.016
positive regulation of cell death GO:0010942 184 0.016
cellular component assembly GO:0022607 360 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of signaling GO:0023056 270 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
head development GO:0060322 247 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
response to other organism GO:0051707 220 0.016
regulation of anatomical structure size GO:0090066 135 0.016
regulation of system process GO:0044057 208 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
response to estradiol GO:0032355 164 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
macromolecular complex assembly GO:0065003 273 0.015
regeneration GO:0031099 163 0.015
cellular response to stress GO:0033554 269 0.015
response to inorganic substance GO:0010035 377 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
negative regulation of developmental process GO:0051093 125 0.015
response to glucocorticoid GO:0051384 223 0.015
response to lipopolysaccharide GO:0032496 191 0.015
ras protein signal transduction GO:0007265 29 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
purine containing compound metabolic process GO:0072521 253 0.015
positive regulation of kinase activity GO:0033674 77 0.015
single organism behavior GO:0044708 130 0.015
oligopeptide transport GO:0006857 4 0.014
regulation of neuron death GO:1901214 115 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
localization of cell GO:0051674 202 0.014
reproductive process GO:0022414 372 0.014
Rat
response to corticosteroid GO:0031960 235 0.014
positive regulation of protein modification process GO:0031401 142 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
cell migration GO:0016477 197 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
macromolecule localization GO:0033036 252 0.013
response to external biotic stimulus GO:0043207 221 0.013
response to wounding GO:0009611 254 0.013
aging GO:0007568 241 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of dna metabolic process GO:0051052 60 0.013
response to carbohydrate GO:0009743 183 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
response to hexose GO:0009746 144 0.013
gland development GO:0048732 155 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
regulation of membrane potential GO:0042391 110 0.013
histone h3 k9 methylation GO:0051567 1 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
immune system process GO:0002376 204 0.013
metal ion transport GO:0030001 289 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
nucleotide catabolic process GO:0009166 139 0.013
cellular response to acid chemical GO:0071229 75 0.013
response to glucose GO:0009749 136 0.013
epithelium development GO:0060429 96 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
regulation of transferase activity GO:0051338 123 0.013
developmental induction GO:0031128 2 0.013
eye morphogenesis GO:0048592 4 0.013
growth GO:0040007 165 0.012
ion homeostasis GO:0050801 212 0.012
negative regulation of molecular function GO:0044092 133 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
Rat
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
response to bacterium GO:0009617 200 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
establishment of protein localization GO:0045184 141 0.012
single organism reproductive process GO:0044702 297 0.012
Rat
response to peptide GO:1901652 292 0.012
nucleoside metabolic process GO:0009116 179 0.012
regulation of catabolic process GO:0009894 113 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
cell part morphogenesis GO:0032990 123 0.012
cellular cation homeostasis GO:0030003 180 0.012
reproduction GO:0000003 245 0.012
Rat
cellular macromolecule localization GO:0070727 122 0.012
neuron apoptotic process GO:0051402 88 0.012
muscle system process GO:0003012 115 0.012
multicellular organism reproduction GO:0032504 233 0.012
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
appendage morphogenesis GO:0035107 4 0.012
cell motility GO:0048870 202 0.011
glandular epithelial cell differentiation GO:0002067 4 0.011
specification of organ identity GO:0010092 2 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
limb morphogenesis GO:0035108 4 0.011
secretion GO:0046903 307 0.011
histone h3 acetylation GO:0043966 2 0.011
response to cytokine GO:0034097 215 0.011
programmed cell death GO:0012501 392 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
male gamete generation GO:0048232 99 0.011
Rat
inflammatory response GO:0006954 150 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of cell death GO:0060548 229 0.011
aromatic compound catabolic process GO:0019439 168 0.011
ncrna processing GO:0034470 3 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.011
muscle tissue development GO:0060537 58 0.011
protein complex subunit organization GO:0071822 302 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
organ formation GO:0048645 3 0.011
gastrulation GO:0007369 2 0.011
negative regulation of signal transduction GO:0009968 83 0.011
cellular ion homeostasis GO:0006873 184 0.011
muscle structure development GO:0061061 87 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
bmp signaling pathway GO:0030509 4 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
multicellular organism growth GO:0035264 1 0.010
negative regulation of nervous system development GO:0051961 79 0.010
cytoplasmic transport GO:0016482 115 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
purine containing compound catabolic process GO:0072523 138 0.010
cell fate determination GO:0001709 2 0.010
response to vitamin GO:0033273 131 0.010
prostate gland morphogenesis GO:0060512 2 0.010
multi organism reproductive process GO:0044703 262 0.010
Rat
regulation of protein localization GO:0032880 81 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
tube development GO:0035295 89 0.010
striated muscle tissue development GO:0014706 58 0.010
cell type specific apoptotic process GO:0097285 134 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
response to decreased oxygen levels GO:0036293 237 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
rna catabolic process GO:0006401 3 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
neuron projection morphogenesis GO:0048812 122 0.010
guanosine containing compound catabolic process GO:1901069 71 0.010
positive regulation of transferase activity GO:0051347 81 0.010

Brd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012