Rattus norvegicus

0 known processes

Brd4

bromodomain containing 4

Brd4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.348
regulation of rna biosynthetic process GO:2001141 381 0.347
regulation of nucleic acid templated transcription GO:1903506 380 0.270
rna biosynthetic process GO:0032774 380 0.238
positive regulation of cellular biosynthetic process GO:0031328 295 0.189
positive regulation of nucleic acid templated transcription GO:1903508 197 0.176
positive regulation of gene expression GO:0010628 244 0.167
rna metabolic process GO:0016070 406 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.158
regulation of rna metabolic process GO:0051252 391 0.151
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.143
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.137
cellular response to endogenous stimulus GO:0071495 377 0.136
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.125
positive regulation of rna metabolic process GO:0051254 203 0.121
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.117
positive regulation of biosynthetic process GO:0009891 319 0.117
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.111
regulation of transcription dna templated GO:0006355 374 0.110
nucleic acid templated transcription GO:0097659 379 0.102
positive regulation of rna biosynthetic process GO:1902680 197 0.098
positive regulation of programmed cell death GO:0043068 157 0.095
locomotion GO:0040011 237 0.095
negative regulation of metabolic process GO:0009892 331 0.094
negative regulation of macromolecule metabolic process GO:0010605 260 0.093
apoptotic process GO:0006915 381 0.092
negative regulation of rna biosynthetic process GO:1902679 118 0.091
positive regulation of transcription dna templated GO:0045893 197 0.091
regulation of programmed cell death GO:0043067 341 0.091
histone modification GO:0016570 30 0.077
positive regulation of nervous system development GO:0051962 178 0.076
positive regulation of apoptotic process GO:0043065 154 0.074
positive regulation of cell differentiation GO:0045597 217 0.068
regulation of cell differentiation GO:0045595 320 0.067
negative regulation of nucleic acid templated transcription GO:1903507 117 0.065
regulation of neuron differentiation GO:0045664 208 0.065
response to fungicide GO:0060992 20 0.064
chromatin organization GO:0006325 34 0.064
Rat
regulation of molecular function GO:0065009 398 0.062
negative regulation of transcription dna templated GO:0045892 116 0.061
regulation of multicellular organismal development GO:2000026 376 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.059
immune system process GO:0002376 204 0.058
positive regulation of multicellular organismal process GO:0051240 387 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.056
head development GO:0060322 247 0.055
brain development GO:0007420 247 0.054
immune system development GO:0002520 41 0.053
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.053
negative regulation of cellular biosynthetic process GO:0031327 161 0.053
regulation of cell development GO:0060284 263 0.052
regulation of apoptotic process GO:0042981 335 0.052
cellular response to growth factor stimulus GO:0071363 162 0.051
central nervous system development GO:0007417 311 0.051
regulation of nervous system development GO:0051960 264 0.050
negative regulation of gene expression GO:0010629 199 0.049
organic acid metabolic process GO:0006082 292 0.049
single organism organelle organization GO:1902589 180 0.048
oxoacid metabolic process GO:0043436 290 0.048
cellular amino acid metabolic process GO:0006520 107 0.047
covalent chromatin modification GO:0016569 30 0.046
positive regulation of developmental process GO:0051094 283 0.045
positive regulation of cell death GO:0010942 184 0.044
neuron projection development GO:0031175 273 0.044
protein phosphorylation GO:0006468 345 0.044
regulation of phosphate metabolic process GO:0019220 349 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.044
response to oxidative stress GO:0006979 186 0.043
regulation of cell projection organization GO:0031344 175 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
carboxylic acid metabolic process GO:0019752 289 0.042
positive regulation of neurogenesis GO:0050769 165 0.041
cell part morphogenesis GO:0032990 123 0.041
regulation of neurogenesis GO:0050767 247 0.041
chromatin modification GO:0016568 33 0.040
Rat
cellular ketone metabolic process GO:0042180 51 0.040
programmed cell death GO:0012501 392 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.039
cellular amine metabolic process GO:0044106 38 0.038
negative regulation of biosynthetic process GO:0009890 168 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
amine metabolic process GO:0009308 38 0.037
response to toxic substance GO:0009636 133 0.037
regulation of anatomical structure morphogenesis GO:0022603 141 0.036
cell projection organization GO:0030030 302 0.036
cellular response to stress GO:0033554 269 0.036
positive regulation of cell projection organization GO:0031346 111 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
cellular component movement GO:0006928 248 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.035
axonogenesis GO:0007409 71 0.035
regulation of cellular component organization GO:0051128 368 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.035
regulation of neuron projection development GO:0010975 161 0.034
positive regulation of cell development GO:0010720 176 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular component biogenesis GO:0044085 368 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
Rat
response to growth factor GO:0070848 189 0.032
response to metal ion GO:0010038 253 0.031
motor neuron axon guidance GO:0008045 1 0.031
histone h3 acetylation GO:0043966 2 0.031
cell motility GO:0048870 202 0.031
localization of cell GO:0051674 202 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
regulation of cell motility GO:2000145 131 0.029
cell migration GO:0016477 197 0.029
cellular response to lipid GO:0071396 201 0.028
protein localization GO:0008104 191 0.027
regulation of axonogenesis GO:0050770 37 0.027
regulation of locomotion GO:0040012 148 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
multicellular organism reproduction GO:0032504 233 0.026
Rat
positive regulation of neuron differentiation GO:0045666 126 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.026
regulation of response to external stimulus GO:0032101 106 0.025
neuron differentiation GO:0030182 368 0.025
negative regulation of protein metabolic process GO:0051248 114 0.025
peptidyl amino acid modification GO:0018193 126 0.024
neuron projection morphogenesis GO:0048812 122 0.024
chromosome organization GO:0051276 36 0.024
Rat
negative regulation of molecular function GO:0044092 133 0.024
response to wounding GO:0009611 254 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
growth GO:0040007 165 0.023
muscle system process GO:0003012 115 0.023
response to lipopolysaccharide GO:0032496 191 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
cell cell signaling GO:0007267 335 0.023
regulation of transforming growth factor beta3 production GO:0032910 2 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
regulation of catalytic activity GO:0050790 304 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
negative regulation of cellular component organization GO:0051129 83 0.022
negative regulation of apoptotic process GO:0043066 181 0.021
eye morphogenesis GO:0048592 4 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
immune response GO:0006955 104 0.021
cell adhesion GO:0007155 110 0.021
axon development GO:0061564 96 0.021
spindle organization GO:0007051 2 0.021
sex differentiation GO:0007548 113 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
organelle organization GO:0006996 266 0.020
Rat
gonad development GO:0008406 104 0.020
single organism biosynthetic process GO:0044711 342 0.020
regulation of cell morphogenesis GO:0022604 77 0.020
glandular epithelial cell differentiation GO:0002067 4 0.020
intracellular signal transduction GO:0035556 314 0.020
developmental process involved in reproduction GO:0003006 159 0.019
regulation of phosphorylation GO:0042325 248 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
regulation of protein modification process GO:0031399 194 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
proteolysis GO:0006508 175 0.019
regulation of muscle system process GO:0090257 79 0.018
regulation of system process GO:0044057 208 0.018
developmental growth involved in morphogenesis GO:0060560 33 0.018
cell morphogenesis involved in differentiation GO:0000904 119 0.018
regulation of cytoskeleton organization GO:0051493 49 0.018
positive regulation of tolerance induction GO:0002645 1 0.018
hematopoietic progenitor cell differentiation GO:0002244 2 0.017
multi organism reproductive process GO:0044703 262 0.017
Rat
regulation of organelle organization GO:0033043 80 0.017
positive regulation of molecular function GO:0044093 230 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
biological adhesion GO:0022610 110 0.017
cell fate determination GO:0001709 2 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of extent of cell growth GO:0061387 25 0.017
negative regulation of cell communication GO:0010648 158 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
synaptic transmission GO:0007268 235 0.016
posttranscriptional regulation of gene expression GO:0010608 37 0.016
response to retinoic acid GO:0032526 63 0.016
muscle structure development GO:0061061 87 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular component assembly GO:0022607 360 0.016
positive regulation of cellular component biogenesis GO:0044089 55 0.016
regulation of cell proliferation GO:0042127 359 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.016
metal ion homeostasis GO:0055065 186 0.016
male gamete generation GO:0048232 99 0.015
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
mirna metabolic process GO:0010586 1 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
regulation of bmp signaling pathway GO:0030510 2 0.015
forebrain development GO:0030900 98 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
response to acid chemical GO:0001101 222 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
regulation of cell migration GO:0030334 128 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
embryonic pattern specification GO:0009880 1 0.015
cellular component morphogenesis GO:0032989 155 0.015
developmental growth GO:0048589 100 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
response to nutrient levels GO:0031667 370 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
actin cytoskeleton organization GO:0030036 73 0.014
protein autophosphorylation GO:0046777 66 0.014
negative regulation of cell death GO:0060548 229 0.014
gamete generation GO:0007276 124 0.014
Rat
axis specification GO:0009798 4 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of signal transduction GO:0009966 318 0.014
regulation of protein metabolic process GO:0051246 289 0.014
response to extracellular stimulus GO:0009991 380 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.013
regeneration GO:0031099 163 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
negative regulation of signaling GO:0023057 157 0.013
cell cycle GO:0007049 101 0.013
neurological system process GO:0050877 219 0.013
cellular chemical homeostasis GO:0055082 247 0.013
response to estrogen GO:0043627 232 0.013
neuronal stem cell maintenance GO:0097150 2 0.013
cellular protein localization GO:0034613 122 0.013
response to cytokine GO:0034097 215 0.013
regulation of chemotaxis GO:0050920 29 0.013
response to reactive oxygen species GO:0000302 120 0.013
cell morphogenesis GO:0000902 142 0.013
regulation of protein transport GO:0051223 68 0.013
histone methylation GO:0016571 3 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
anterior posterior pattern specification GO:0009952 1 0.012
bmp signaling pathway GO:0030509 4 0.012
reproductive system development GO:0061458 128 0.012
cell cycle process GO:0022402 57 0.012
cellular response to acid chemical GO:0071229 75 0.012
translation GO:0006412 35 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
development of primary sexual characteristics GO:0045137 107 0.012
protein deubiquitination GO:0016579 4 0.012
response to monosaccharide GO:0034284 159 0.012
macromolecular complex assembly GO:0065003 273 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
neuron development GO:0048666 286 0.012
camera type eye morphogenesis GO:0048593 2 0.012
gland development GO:0048732 155 0.012
negative regulation of signal transduction GO:0009968 83 0.012
dna methylation or demethylation GO:0044728 8 0.012
regulation of axon extension GO:0030516 24 0.012
hair cycle GO:0042633 3 0.012
regulation of viral transcription GO:0046782 2 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
hippocampus development GO:0021766 30 0.011
viral transcription GO:0019083 2 0.011
reproductive structure development GO:0048608 128 0.011
chemical homeostasis GO:0048878 292 0.011
response to oxygen levels GO:0070482 265 0.011
cellular homeostasis GO:0019725 252 0.011
chemosensory behavior GO:0007635 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of protein kinase activity GO:0045859 105 0.011
defense response GO:0006952 194 0.011
tissue development GO:0009888 252 0.011
homeostatic process GO:0042592 331 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to biotic stimulus GO:0009607 226 0.011
behavior GO:0007610 205 0.011
cytoskeleton organization GO:0007010 111 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
protein complex biogenesis GO:0070271 263 0.011
regulation of secretion by cell GO:1903530 208 0.011
regulation of secretion GO:0051046 224 0.011
hepaticobiliary system development GO:0061008 90 0.011
positive regulation of cell communication GO:0010647 271 0.011
hemopoiesis GO:0030097 34 0.011
regulation of cell growth GO:0001558 85 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
positive regulation of adherens junction organization GO:1903393 2 0.011
regulation of cell cycle GO:0051726 73 0.011
response to ethanol GO:0045471 162 0.011
regulation of growth GO:0040008 105 0.011
mitotic spindle organization GO:0007052 2 0.011
cell type specific apoptotic process GO:0097285 134 0.011
cellular calcium ion homeostasis GO:0006874 160 0.010
organic substance catabolic process GO:1901575 316 0.010
protein complex subunit organization GO:0071822 302 0.010
response to decreased oxygen levels GO:0036293 237 0.010
cellular catabolic process GO:0044248 295 0.010
cellular response to ketone GO:1901655 51 0.010
nucleotide metabolic process GO:0009117 279 0.010
single organism cellular localization GO:1902580 102 0.010

Brd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org