Rattus norvegicus

0 known processes

C1qc

complement component 1, q subcomponent, C chain

(Aliases: C1qg,MGC105681)

C1qc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to corticosteroid GO:0031960 235 0.755
Rat
myeloid progenitor cell differentiation GO:0002318 1 0.506
response to glucocorticoid GO:0051384 223 0.425
Rat
defense response GO:0006952 194 0.392
immune system process GO:0002376 204 0.336
Human Zebrafish
pro t cell differentiation GO:0002572 1 0.329
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.326
aging GO:0007568 241 0.324
Rat
response to nutrient GO:0007584 248 0.303
brain development GO:0007420 247 0.294
Rat
cell migration involved in metanephros development GO:0035788 2 0.280
lymphoid progenitor cell differentiation GO:0002320 2 0.249
granulocyte chemotaxis GO:0071621 15 0.248
positive regulation of multicellular organismal process GO:0051240 387 0.238
head development GO:0060322 247 0.221
Rat
response to extracellular stimulus GO:0009991 380 0.206
response to nutrient levels GO:0031667 370 0.203
regulation of cell activation GO:0050865 50 0.187
programmed cell death GO:0012501 392 0.166
cell junction maintenance GO:0034331 1 0.154
positive regulation of macrophage chemotaxis GO:0010759 2 0.153
organ regeneration GO:0031100 101 0.145
response to cytokine GO:0034097 215 0.143
negative regulation of b cell differentiation GO:0045578 1 0.142
homeostatic process GO:0042592 331 0.140
apoptotic process GO:0006915 381 0.137
regulation of cell proliferation GO:0042127 359 0.132
response to other organism GO:0051707 220 0.122
regulation of programmed cell death GO:0043067 341 0.121
negative regulation of multicellular organismal process GO:0051241 203 0.120
Human
regulation of macrophage chemotaxis GO:0010758 2 0.118
rhythmic process GO:0048511 156 0.114
neurological system process GO:0050877 219 0.108
central nervous system development GO:0007417 311 0.108
Rat
inflammatory response GO:0006954 150 0.107
cellular chemical homeostasis GO:0055082 247 0.107
positive regulation of cell differentiation GO:0045597 217 0.105
cellular response to oxygen containing compound GO:1901701 386 0.100
cellular cation homeostasis GO:0030003 180 0.097
complement activation GO:0006956 11 0.093
Zebrafish
kidney mesenchyme development GO:0072074 2 0.091
response to acid chemical GO:0001101 222 0.091
acute phase response GO:0006953 20 0.089
positive regulation of response to stimulus GO:0048584 285 0.087
Zebrafish
cellular response to lipid GO:0071396 201 0.086
cellular divalent inorganic cation homeostasis GO:0072503 162 0.081
response to metal ion GO:0010038 253 0.079
cellular response to growth factor stimulus GO:0071363 162 0.077
negative regulation of apoptotic process GO:0043066 181 0.077
regulation of cell differentiation GO:0045595 320 0.077
Human
b cell mediated immunity GO:0019724 4 0.072
Zebrafish
complement receptor mediated signaling pathway GO:0002430 2 0.072
reproductive process GO:0022414 372 0.071
cellular component assembly GO:0022607 360 0.070
cellular metal ion homeostasis GO:0006875 172 0.070
amine metabolic process GO:0009308 38 0.070
cellular calcium ion homeostasis GO:0006874 160 0.069
regulation of locomotion GO:0040012 148 0.067
negative regulation of cell death GO:0060548 229 0.067
multicellular organismal reproductive process GO:0048609 233 0.067
positive regulation of immune system process GO:0002684 90 0.063
Zebrafish
response to external biotic stimulus GO:0043207 221 0.062
divalent inorganic cation homeostasis GO:0072507 165 0.061
response to vitamin GO:0033273 131 0.061
regulation of catalytic activity GO:0050790 304 0.060
metanephric glomerulus morphogenesis GO:0072275 1 0.059
neuron differentiation GO:0030182 368 0.059
response to biotic stimulus GO:0009607 226 0.059
positive regulation of developmental process GO:0051094 283 0.058
response to hexose GO:0009746 144 0.058
aminoglycan biosynthetic process GO:0006023 4 0.058
male sex determination GO:0030238 2 0.058
cation homeostasis GO:0055080 195 0.058
chemical homeostasis GO:0048878 292 0.057
cellular amine metabolic process GO:0044106 38 0.056
cardiovascular system development GO:0072358 134 0.056
comma shaped body morphogenesis GO:0072049 2 0.055
regulation of apoptotic process GO:0042981 335 0.052
positive regulation of secretion GO:0051047 140 0.052
neuron death GO:0070997 127 0.051
response to growth factor GO:0070848 189 0.050
muscle structure development GO:0061061 87 0.050
regulation of neurogenesis GO:0050767 247 0.047
cellular response to organic cyclic compound GO:0071407 202 0.046
cellular ion homeostasis GO:0006873 184 0.046
regulation of b cell differentiation GO:0045577 1 0.046
s shaped body morphogenesis GO:0072050 2 0.045
ion homeostasis GO:0050801 212 0.045
metal ion homeostasis GO:0055065 186 0.044
positive regulation of response to wounding GO:1903036 34 0.044
antigen processing and presentation of peptide antigen GO:0048002 2 0.044
antigen processing and presentation GO:0019882 2 0.044
cellular response to endogenous stimulus GO:0071495 377 0.043
purine nucleotide metabolic process GO:0006163 229 0.043
cellular homeostasis GO:0019725 252 0.041
response to sterol GO:0036314 13 0.041
cytosolic calcium ion homeostasis GO:0051480 140 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.040
cellular response to insulin stimulus GO:0032869 81 0.040
regulation of calcium ion transport GO:0051924 77 0.040
regulation of cellular component organization GO:0051128 368 0.039
renal system development GO:0072001 67 0.039
tissue development GO:0009888 252 0.039
response to monosaccharide GO:0034284 159 0.038
response to glucose GO:0009749 136 0.038
purine containing compound metabolic process GO:0072521 253 0.038
cellular response to cytokine stimulus GO:0071345 127 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
Human
positive regulation of neuron differentiation GO:0045666 126 0.037
regulation of immune system process GO:0002682 123 0.037
Human Zebrafish
organ morphogenesis GO:0009887 75 0.036
response to carbohydrate GO:0009743 183 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
regulation of peptide hormone secretion GO:0090276 80 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
regeneration GO:0031099 163 0.036
regulation of phosphate metabolic process GO:0019220 349 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
eye development GO:0001654 50 0.034
response to insulin GO:0032868 133 0.034
response to wounding GO:0009611 254 0.034
response to peptide GO:1901652 292 0.034
cell growth GO:0016049 104 0.034
cell migration involved in kidney development GO:0035787 2 0.034
positive regulation of neurogenesis GO:0050769 165 0.033
tissue remodeling GO:0048771 40 0.033
positive regulation of response to external stimulus GO:0032103 51 0.033
growth GO:0040007 165 0.032
regulation of neuron differentiation GO:0045664 208 0.032
signal transduction by phosphorylation GO:0023014 144 0.031
response to peptide hormone GO:0043434 278 0.031
urogenital system development GO:0001655 78 0.031
macrophage chemotaxis GO:0048246 2 0.030
cellular response to organonitrogen compound GO:0071417 197 0.030
regulation of nervous system development GO:0051960 264 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
calcium ion homeostasis GO:0055074 162 0.030
striated muscle tissue development GO:0014706 58 0.030
leukocyte apoptotic process GO:0071887 6 0.029
reproduction GO:0000003 245 0.029
regulation of neuron projection development GO:0010975 161 0.029
negative regulation of molecular function GO:0044092 133 0.029
response to estrogen GO:0043627 232 0.029
mitotic spindle organization GO:0007052 2 0.028
protein complex biogenesis GO:0070271 263 0.028
macromolecular complex assembly GO:0065003 273 0.028
regulation of secretion by cell GO:1903530 208 0.028
cell activation GO:0001775 97 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
regulation of protein metabolic process GO:0051246 289 0.027
single organism reproductive process GO:0044702 297 0.027
nucleotide metabolic process GO:0009117 279 0.027
response to ethanol GO:0045471 162 0.026
negative regulation of neuron death GO:1901215 69 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
neuron development GO:0048666 286 0.025
cytokine mediated signaling pathway GO:0019221 43 0.025
immune response GO:0006955 104 0.025
Zebrafish
action potential GO:0001508 54 0.025
regulation of cell development GO:0060284 263 0.025
immune effector process GO:0002252 53 0.025
Zebrafish
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
positive regulation of neuron projection development GO:0010976 99 0.024
negative regulation of peptidase activity GO:0010466 38 0.024
response to estradiol GO:0032355 164 0.024
positive regulation of signaling GO:0023056 270 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
response to lipopolysaccharide GO:0032496 191 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
camera type eye development GO:0043010 48 0.024
developmental process involved in reproduction GO:0003006 159 0.024
vasculature development GO:0001944 70 0.024
cytoskeleton organization GO:0007010 111 0.023
regulation of lymphocyte migration GO:2000401 1 0.023
glucose homeostasis GO:0042593 75 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
cell cycle GO:0007049 101 0.022
regulation of cell projection organization GO:0031344 175 0.022
positive regulation of molecular function GO:0044093 230 0.022
muscle tissue development GO:0060537 58 0.022
rna metabolic process GO:0016070 406 0.022
positive regulation of growth GO:0045927 55 0.022
muscle contraction GO:0006936 88 0.022
negative regulation of developmental process GO:0051093 125 0.022
Human
regulation of actin filament based process GO:0032970 42 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of homeostatic process GO:0032844 101 0.021
regulation of phosphorylation GO:0042325 248 0.021
cellular response to lipopolysaccharide GO:0071222 55 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
immunoglobulin mediated immune response GO:0016064 4 0.021
Zebrafish
regulation of ion transport GO:0043269 245 0.021
macromolecule localization GO:0033036 252 0.021
organelle organization GO:0006996 266 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.021
carbohydrate homeostasis GO:0033500 75 0.021
regulation of cellular localization GO:0060341 263 0.020
cation transport GO:0006812 382 0.020
nitrogen compound transport GO:0071705 229 0.020
ear development GO:0043583 21 0.020
negative regulation of metabolic process GO:0009892 331 0.020
cellular lipid metabolic process GO:0044255 208 0.020
negative regulation of protein maturation GO:1903318 47 0.020
metal ion transport GO:0030001 289 0.020
muscle system process GO:0003012 115 0.020
circulatory system development GO:0072359 134 0.020
cellular response to external stimulus GO:0071496 118 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
actin cytoskeleton organization GO:0030036 73 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
wound healing GO:0042060 122 0.019
regulation of response to external stimulus GO:0032101 106 0.019
response to inorganic substance GO:0010035 377 0.019
regulation of neuron death GO:1901214 115 0.019
organic acid metabolic process GO:0006082 292 0.019
inner ear development GO:0048839 21 0.019
erk1 and erk2 cascade GO:0070371 48 0.019
negative regulation of fibrinolysis GO:0051918 2 0.019
nucleoside catabolic process GO:0009164 126 0.019
calcium ion transport GO:0006816 131 0.019
positive regulation of hemostasis GO:1900048 4 0.019
regulation of leukocyte chemotaxis GO:0002688 12 0.018
response to interferon gamma GO:0034341 20 0.018
regulation of molecular function GO:0065009 398 0.018
camp metabolic process GO:0046058 63 0.018
negative regulation of gene expression GO:0010629 199 0.018
glycosaminoglycan biosynthetic process GO:0006024 4 0.018
regulation of system process GO:0044057 208 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
response to camp GO:0051591 91 0.018
glial cell differentiation GO:0010001 65 0.018
response to organophosphorus GO:0046683 102 0.018
protein complex subunit organization GO:0071822 302 0.018
positive regulation of secretion by cell GO:1903532 128 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of growth GO:0040008 105 0.017
cell projection organization GO:0030030 302 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of cell growth GO:0001558 85 0.017
cellular response to hexose stimulus GO:0071331 65 0.017
regulation of hormone levels GO:0010817 187 0.017
regulation of cellular component movement GO:0051270 150 0.017
cellular response to glucose stimulus GO:0071333 65 0.017
actin filament based process GO:0030029 86 0.017
localization of cell GO:0051674 202 0.017
positive regulation of blood coagulation GO:0030194 4 0.017
response to retinoic acid GO:0032526 63 0.016
cellular component maintenance GO:0043954 4 0.016
developmental growth GO:0048589 100 0.016
establishment of protein localization GO:0045184 141 0.016
glomerulus morphogenesis GO:0072102 1 0.016
ovulation cycle GO:0042698 67 0.016
hematopoietic progenitor cell differentiation GO:0002244 2 0.016
behavior GO:0007610 205 0.016
mononuclear cell migration GO:0071674 3 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
positive regulation of myeloid leukocyte mediated immunity GO:0002888 4 0.016
leukocyte activation GO:0045321 76 0.016
cellular component biogenesis GO:0044085 368 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
neuron projection development GO:0031175 273 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
response to cholesterol GO:0070723 13 0.015
response to decreased oxygen levels GO:0036293 237 0.015
response to purine containing compound GO:0014074 126 0.015
regulation of rna metabolic process GO:0051252 391 0.015
regulation of hormone secretion GO:0046883 106 0.015
jak stat cascade GO:0007259 26 0.015
sex differentiation GO:0007548 113 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
blood vessel morphogenesis GO:0048514 58 0.014
oxoacid metabolic process GO:0043436 290 0.014
hormone transport GO:0009914 121 0.014
leukocyte differentiation GO:0002521 30 0.014
Human
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
common myeloid progenitor cell proliferation GO:0035726 1 0.014
gamete generation GO:0007276 124 0.014
cellular response to monosaccharide stimulus GO:0071326 67 0.014
cellular response to stress GO:0033554 269 0.014
branched chain amino acid transport GO:0015803 2 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.014
regulation of leukocyte activation GO:0002694 45 0.014
transmembrane transport GO:0055085 412 0.014
development of primary sexual characteristics GO:0045137 107 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
negative regulation of immune system process GO:0002683 39 0.014
Human
positive regulation of nervous system development GO:0051962 178 0.014
negative regulation of innate immune response GO:0045824 4 0.013
metanephric nephron morphogenesis GO:0072273 6 0.013
cellular response to vascular endothelial growth factor stimulus GO:0035924 6 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
negative regulation of lymphocyte activation GO:0051250 10 0.013
regulation of anatomical structure size GO:0090066 135 0.013
positive regulation of transport GO:0051050 245 0.013
triglyceride homeostasis GO:0070328 2 0.013
reproductive structure development GO:0048608 128 0.013
negative regulation of lymphocyte differentiation GO:0045620 2 0.013
regulation of signal transduction GO:0009966 318 0.013
retina development in camera type eye GO:0060041 27 0.013
protein complex assembly GO:0006461 263 0.013
pro b cell differentiation GO:0002328 2 0.013
regulation of response to wounding GO:1903034 69 0.013
regulation of cytokinesis GO:0032465 3 0.013
intracellular signal transduction GO:0035556 314 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.012
negative regulation of glucose import GO:0046325 4 0.012
organic anion transport GO:0015711 132 0.012
single organism organelle organization GO:1902589 180 0.012
male gamete generation GO:0048232 99 0.012
innate immune response GO:0045087 35 0.012
phospholipid metabolic process GO:0006644 61 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
single organism catabolic process GO:0044712 283 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
muscle cell differentiation GO:0042692 52 0.012
negative regulation of dopamine secretion GO:0033602 4 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of peptide transport GO:0090087 87 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
lipid storage GO:0019915 1 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of protein transport GO:0051223 68 0.012
response to interleukin 1 GO:0070555 55 0.012
response to toxic substance GO:0009636 133 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of cell migration GO:0030334 128 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
mapk cascade GO:0000165 140 0.011
regulation of neurological system process GO:0031644 43 0.011
metanephric comma shaped body morphogenesis GO:0072278 2 0.011
heart development GO:0007507 72 0.011
peptide transport GO:0015833 97 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
multicellular organismal signaling GO:0035637 44 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of protein processing GO:0010955 47 0.011
positive regulation of gene expression GO:0010628 244 0.011
angiogenesis GO:0001525 53 0.011
cellular response to metal ion GO:0071248 55 0.011
fibrinolysis GO:0042730 2 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to hypoxia GO:0001666 231 0.011
proteolysis GO:0006508 175 0.011
acute inflammatory response GO:0002526 58 0.011
metanephric glomerulus development GO:0072224 3 0.011
locomotion GO:0040011 237 0.010
multicellular organism reproduction GO:0032504 233 0.010
negative regulation of hydrolase activity GO:0051346 52 0.010
positive regulation of cell growth GO:0030307 44 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
signal release GO:0023061 145 0.010
female pregnancy GO:0007565 122 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
response to amino acid GO:0043200 75 0.010
regulation of chemotaxis GO:0050920 29 0.010
potassium ion transport GO:0006813 97 0.010
positive regulation of chemokine production GO:0032722 4 0.010
neuronal action potential GO:0019228 35 0.010
multi organism reproductive process GO:0044703 262 0.010
response to ketone GO:1901654 182 0.010
protein localization GO:0008104 191 0.010
blood circulation GO:0008015 183 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010

C1qc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
cardiovascular system disease DOID:1287 0 0.026
vascular disease DOID:178 0 0.026
musculoskeletal system disease DOID:17 0 0.023
skin disease DOID:37 0 0.013
integumentary system disease DOID:16 0 0.013