Rattus norvegicus

0 known processes

C4bpb

complement component 4 binding protein, beta

(Aliases: C4bp-ps1,MGC108727)

C4bpb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.358
regulation of nervous system development GO:0051960 264 0.227
protein maturation GO:0051604 68 0.211
Human
regulation of catalytic activity GO:0050790 304 0.186
regulation of programmed cell death GO:0043067 341 0.181
positive regulation of multicellular organismal process GO:0051240 387 0.177
response to nutrient GO:0007584 248 0.137
regulation of phosphorus metabolic process GO:0051174 349 0.124
intracellular signal transduction GO:0035556 314 0.118
response to nutrient levels GO:0031667 370 0.118
response to metal ion GO:0010038 253 0.095
single organism biosynthetic process GO:0044711 342 0.095
regulation of molecular function GO:0065009 398 0.089
negative regulation of programmed cell death GO:0043069 183 0.086
programmed cell death GO:0012501 392 0.085
regulation of serine type endopeptidase activity GO:1900003 1 0.085
negative regulation of serine type endopeptidase activity GO:1900004 1 0.084
negative regulation of cell death GO:0060548 229 0.079
positive regulation of nervous system development GO:0051962 178 0.070
multi organism reproductive process GO:0044703 262 0.070
reproduction GO:0000003 245 0.069
regulation of serine type peptidase activity GO:1902571 1 0.069
lipid biosynthetic process GO:0008610 128 0.069
regulation of hydrolase activity GO:0051336 143 0.069
positive regulation of response to stimulus GO:0048584 285 0.068
Human
negative regulation of gene expression GO:0010629 199 0.067
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.066
Human
apoptotic process GO:0006915 381 0.066
amide biosynthetic process GO:0043604 10 0.065
regulation of neuron differentiation GO:0045664 208 0.065
cellular response to endogenous stimulus GO:0071495 377 0.064
reproductive process GO:0022414 372 0.061
regulation of cell proliferation GO:0042127 359 0.061
negative regulation of metabolic process GO:0009892 331 0.060
Human
protein processing GO:0016485 68 0.059
Human
cellular amino acid metabolic process GO:0006520 107 0.059
protein activation cascade GO:0072376 12 0.059
Human
cellular amine metabolic process GO:0044106 38 0.059
response to peptide hormone GO:0043434 278 0.059
regulation of response to stress GO:0080134 126 0.058
Human
growth GO:0040007 165 0.057
positive regulation of developmental process GO:0051094 283 0.056
defense response GO:0006952 194 0.056
Human
regulation of protein metabolic process GO:0051246 289 0.055
Human
regulation of neuron projection development GO:0010975 161 0.053
response to decreased oxygen levels GO:0036293 237 0.053
ion homeostasis GO:0050801 212 0.053
response to peptide GO:1901652 292 0.053
multicellular organism reproduction GO:0032504 233 0.050
regulation of system process GO:0044057 208 0.050
regulation of apoptotic process GO:0042981 335 0.048
carboxylic acid metabolic process GO:0019752 289 0.048
wound healing GO:0042060 122 0.047
positive regulation of transport GO:0051050 245 0.047
positive regulation of protein metabolic process GO:0051247 178 0.047
Human
regulation of protein phosphorylation GO:0001932 183 0.047
regulation of neurogenesis GO:0050767 247 0.047
regulation of cellular localization GO:0060341 263 0.047
cellular ketone metabolic process GO:0042180 51 0.046
response to acid chemical GO:0001101 222 0.046
cellular response to organonitrogen compound GO:0071417 197 0.046
immune response GO:0006955 104 0.046
Human
response to biotic stimulus GO:0009607 226 0.045
regulation of protein processing GO:0070613 50 0.045
Human
lipid transport GO:0006869 61 0.044
response to hexose GO:0009746 144 0.044
negative regulation of response to stimulus GO:0048585 155 0.044
Human
macromolecule localization GO:0033036 252 0.044
regulation of multicellular organismal development GO:2000026 376 0.044
response to estrogen GO:0043627 232 0.042
response to cytokine GO:0034097 215 0.042
lipid metabolic process GO:0006629 283 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.041
cellular lipid metabolic process GO:0044255 208 0.041
negative regulation of protein maturation GO:1903318 47 0.040
Human
regulation of hormone levels GO:0010817 187 0.040
circulatory system process GO:0003013 183 0.040
cellular chemical homeostasis GO:0055082 247 0.040
metal ion homeostasis GO:0055065 186 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
blood circulation GO:0008015 183 0.038
steroid biosynthetic process GO:0006694 48 0.037
negative regulation of apoptotic process GO:0043066 181 0.037
lipid localization GO:0010876 62 0.037
negative regulation of signaling GO:0023057 157 0.037
positive regulation of intracellular signal transduction GO:1902533 138 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
proteolysis GO:0006508 175 0.036
regulation of phosphorylation GO:0042325 248 0.036
regulation of response to wounding GO:1903034 69 0.035
Human
regulation of signal transduction GO:0009966 318 0.035
regeneration GO:0031099 163 0.034
single organism reproductive process GO:0044702 297 0.034
cellular component assembly GO:0022607 360 0.034
protein phosphorylation GO:0006468 345 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
positive regulation of phosphorylation GO:0042327 177 0.034
response to camp GO:0051591 91 0.034
amine metabolic process GO:0009308 38 0.033
organic acid metabolic process GO:0006082 292 0.033
response to ethanol GO:0045471 162 0.033
cellular ion homeostasis GO:0006873 184 0.033
response to ketone GO:1901654 182 0.032
organophosphate metabolic process GO:0019637 370 0.032
oxoacid metabolic process GO:0043436 290 0.032
regulation of heterotypic cell cell adhesion GO:0034114 2 0.032
organonitrogen compound biosynthetic process GO:1901566 167 0.032
heterotypic cell cell adhesion GO:0034113 2 0.032
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.032
response to vitamin GO:0033273 131 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
homeostatic process GO:0042592 331 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
fibrinolysis GO:0042730 2 0.031
negative regulation of molecular function GO:0044092 133 0.031
positive regulation of signaling GO:0023056 270 0.031
cell projection organization GO:0030030 302 0.031
response to glucocorticoid GO:0051384 223 0.031
epithelial cell proliferation GO:0050673 54 0.030
response to bacterium GO:0009617 200 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
regulation of homeostatic process GO:0032844 101 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.029
feeding behavior GO:0007631 53 0.029
exocytosis GO:0006887 60 0.029
peptidyl tyrosine phosphorylation GO:0018108 72 0.029
neuron differentiation GO:0030182 368 0.029
cellular cation homeostasis GO:0030003 180 0.029
cellular homeostasis GO:0019725 252 0.029
divalent metal ion transport GO:0070838 132 0.028
positive regulation of gene expression GO:0010628 244 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
response to radiation GO:0009314 137 0.028
positive regulation of neuron differentiation GO:0045666 126 0.027
regulation of protein modification process GO:0031399 194 0.027
negative regulation of serine type peptidase activity GO:1902572 1 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
positive regulation of catalytic activity GO:0043085 184 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
biological adhesion GO:0022610 110 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
regulation of ion transport GO:0043269 245 0.026
chemical homeostasis GO:0048878 292 0.026
negative regulation of proteolysis GO:0045861 41 0.026
detection of visible light GO:0009584 3 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
protein complex biogenesis GO:0070271 263 0.025
regulation of cell projection organization GO:0031344 175 0.025
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
negative regulation of endopeptidase activity GO:0010951 36 0.025
organic acid biosynthetic process GO:0016053 83 0.025
negative regulation of peptidase activity GO:0010466 38 0.025
response to fatty acid GO:0070542 65 0.025
regulation of cell differentiation GO:0045595 320 0.025
positive regulation of immune system process GO:0002684 90 0.025
Human
response to glucose GO:0009749 136 0.024
cellular component biogenesis GO:0044085 368 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
response to inorganic substance GO:0010035 377 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
calcium ion transport GO:0006816 131 0.024
immune system process GO:0002376 204 0.024
Human
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
peptidyl amino acid modification GO:0018193 126 0.023
regulation of growth GO:0040008 105 0.023
regulation of cell growth GO:0001558 85 0.023
cytolysis GO:0019835 4 0.023
coagulation GO:0050817 28 0.023
hormone metabolic process GO:0042445 69 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
negative regulation of catalytic activity GO:0043086 103 0.022
macromolecular complex assembly GO:0065003 273 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
response to hypoxia GO:0001666 231 0.022
regulation of response to external stimulus GO:0032101 106 0.022
Human
regulation of endothelial cell apoptotic process GO:2000351 3 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.021
regulation of anatomical structure size GO:0090066 135 0.021
regulation of secretion GO:0051046 224 0.021
regulation of lipid biosynthetic process GO:0046890 38 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
glycerolipid metabolic process GO:0046486 67 0.021
regulation of metal ion transport GO:0010959 118 0.021
anion transport GO:0006820 178 0.021
response to external biotic stimulus GO:0043207 221 0.021
protein complex assembly GO:0006461 263 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
peptidyl tyrosine modification GO:0018212 72 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
positive regulation of extracellular matrix organization GO:1903055 4 0.020
response to carbohydrate GO:0009743 183 0.020
negative regulation of signal transduction GO:0009968 83 0.020
response to other organism GO:0051707 220 0.019
organ regeneration GO:0031100 101 0.019
cellular response to external stimulus GO:0071496 118 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
transmission of nerve impulse GO:0019226 42 0.019
response to insulin GO:0032868 133 0.019
positive regulation of protein modification process GO:0031401 142 0.019
extracellular matrix constituent secretion GO:0070278 4 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
gland development GO:0048732 155 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
regulation of cellular component organization GO:0051128 368 0.018
negative regulation of cell communication GO:0010648 158 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of cell development GO:0060284 263 0.018
heart morphogenesis GO:0003007 3 0.018
tissue development GO:0009888 252 0.018
regulation of secretion by cell GO:1903530 208 0.018
single organism catabolic process GO:0044712 283 0.018
positive regulation of cell development GO:0010720 176 0.018
glucose homeostasis GO:0042593 75 0.017
neuron development GO:0048666 286 0.017
organic substance catabolic process GO:1901575 316 0.017
Human
positive regulation of homeostatic process GO:0032846 49 0.017
cell cell signaling GO:0007267 335 0.017
circadian rhythm GO:0007623 88 0.017
cell type specific apoptotic process GO:0097285 134 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
intracellular transport GO:0046907 185 0.017
cardiac chamber development GO:0003205 1 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.016
amide transport GO:0042886 105 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
catenin import into nucleus GO:0035411 1 0.016
sexual reproduction GO:0019953 148 0.016
response to purine containing compound GO:0014074 126 0.016
alcohol metabolic process GO:0006066 77 0.016
regulation of body fluid levels GO:0050878 90 0.016
response to oxygen levels GO:0070482 265 0.016
cation homeostasis GO:0055080 195 0.016
regulation of renal sodium excretion GO:0035813 20 0.016
small molecule biosynthetic process GO:0044283 124 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
regulation of protein maturation GO:1903317 50 0.016
Human
cell growth GO:0016049 104 0.016
single organism cellular localization GO:1902580 102 0.016
negative regulation of protein metabolic process GO:0051248 114 0.015
Human
negative regulation of protein processing GO:0010955 47 0.015
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.015
developmental growth GO:0048589 100 0.015
regulation of neuron death GO:1901214 115 0.015
cellular amide metabolic process GO:0043603 44 0.015
response to corticosteroid GO:0031960 235 0.015
hormone transport GO:0009914 121 0.015
regulation of peptidase activity GO:0052547 55 0.015
organic hydroxy compound transport GO:0015850 77 0.015
regulation of ion homeostasis GO:2000021 63 0.015
brain renin angiotensin system GO:0002035 3 0.015
response to activity GO:0014823 73 0.014
stress activated protein kinase signaling cascade GO:0031098 37 0.014
regulation of catabolic process GO:0009894 113 0.014
Human
positive regulation of heterotypic cell cell adhesion GO:0034116 1 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
regulation of proteolysis GO:0030162 66 0.014
positive regulation of blood circulation GO:1903524 65 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
inflammatory response GO:0006954 150 0.014
Human
response to vitamin b6 GO:0034516 1 0.014
ion transmembrane transport GO:0034220 365 0.014
sulfur compound metabolic process GO:0006790 70 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
secretion GO:0046903 307 0.014
nucleotide metabolic process GO:0009117 279 0.014
complement activation GO:0006956 11 0.014
Human
cellular response to stress GO:0033554 269 0.014
positive regulation of cellular component organization GO:0051130 200 0.013
neurological system process GO:0050877 219 0.013
sequestering of metal ion GO:0051238 9 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
regulation of inflammatory response GO:0050727 48 0.013
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
regulation of endopeptidase activity GO:0052548 51 0.013
acute inflammatory response GO:0002526 58 0.013
Human
small molecule catabolic process GO:0044282 59 0.013
regulation of muscle system process GO:0090257 79 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
vesicle mediated transport GO:0016192 181 0.013
regulation of blood circulation GO:1903522 110 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cell adhesion GO:0007155 110 0.013
regulation of calcium ion transport GO:0051924 77 0.013
protein complex subunit organization GO:0071822 302 0.013
negative regulation of neuron death GO:1901215 69 0.013
hemostasis GO:0007599 26 0.013
response to estradiol GO:0032355 164 0.012
response to wounding GO:0009611 254 0.012
Human
monocarboxylic acid transport GO:0015718 52 0.012
divalent inorganic cation transport GO:0072511 134 0.012
axis specification GO:0009798 4 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
leukocyte mediated immunity GO:0002443 28 0.012
Human
cardiovascular system development GO:0072358 134 0.012
cell activation GO:0001775 97 0.012
adult locomotory behavior GO:0008344 4 0.012
negative regulation of hydrolase activity GO:0051346 52 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
spermatogenesis GO:0007283 99 0.012
liver development GO:0001889 90 0.012
cardiac ventricle development GO:0003231 1 0.012
positive regulation of molecular function GO:0044093 230 0.012
cellular response to hexose stimulus GO:0071331 65 0.011
plasminogen activation GO:0031639 2 0.011
peptide transport GO:0015833 97 0.011
secretion by cell GO:0032940 248 0.011
fertilization GO:0009566 3 0.011
rhythmic process GO:0048511 156 0.011
positive regulation of cell death GO:0010942 184 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
response to acetate GO:0010034 3 0.011
single organism intracellular transport GO:1902582 166 0.011
positive regulation of lipid biosynthetic process GO:0046889 25 0.011
regulation of transmembrane transport GO:0034762 122 0.011
regulation of blood pressure GO:0008217 83 0.011
protein transport GO:0015031 132 0.011
anterior posterior pattern specification GO:0009952 1 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
vascular process in circulatory system GO:0003018 96 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
response to light stimulus GO:0009416 52 0.011
muscle contraction GO:0006936 88 0.011
renal sodium excretion GO:0035812 20 0.011
regulation of tube size GO:0035150 89 0.011
cytoplasmic transport GO:0016482 115 0.011
macromolecular complex subunit organization GO:0043933 339 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
carbohydrate homeostasis GO:0033500 75 0.010
multicellular organismal signaling GO:0035637 44 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
endothelial cell apoptotic process GO:0072577 3 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
organic anion transport GO:0015711 132 0.010
cellular biogenic amine metabolic process GO:0006576 30 0.010

C4bpb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
hematopoietic system disease DOID:74 0 0.040
blood coagulation disease DOID:1247 0 0.040
immune system disease DOID:2914 0 0.040
inherited blood coagulation disease DOID:2214 0 0.040
eye disease DOID:5614 0 0.039
nervous system disease DOID:863 0 0.039
eye and adnexa disease DOID:1492 0 0.039
sensory system disease DOID:0050155 0 0.039
cardiovascular system disease DOID:1287 0 0.028
muscle tissue disease DOID:66 0 0.022
musculoskeletal system disease DOID:17 0 0.022
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
disease of metabolism DOID:0014667 0 0.020
retinal disease DOID:5679 0 0.017
acquired metabolic disease DOID:0060158 0 0.012