Rattus norvegicus

81 known processes

Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

(Aliases: BIII)

Cacna1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.626
carboxylic acid transport GO:0046942 115 0.527
synaptic transmission GO:0007268 235 0.503
gamma aminobutyric acid transport GO:0015812 8 0.476
negative regulation of vesicle fusion GO:0031339 2 0.456
nitrogen compound transport GO:0071705 229 0.419
monocarboxylic acid transport GO:0015718 52 0.414
regulation of synaptic transmission GO:0050804 141 0.379
regulation of secretion GO:0051046 224 0.364
organic acid transport GO:0015849 116 0.360
phosphatidylinositol dephosphorylation GO:0046856 4 0.328
organic anion transport GO:0015711 132 0.325
synaptic vesicle exocytosis GO:0016079 15 0.319
amino acid transport GO:0006865 70 0.300
secretion GO:0046903 307 0.290
behavior GO:0007610 205 0.273
Mouse Worm Fly
regulation of calcium ion dependent exocytosis GO:0017158 11 0.262
detection of calcium ion GO:0005513 1 0.242
positive regulation of transport GO:0051050 245 0.230
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.216
regulation of synaptic vesicle exocytosis GO:2000300 6 0.210
neurotransmitter secretion GO:0007269 33 0.201
metal ion transport GO:0030001 289 0.200
single organism membrane organization GO:0044802 74 0.197
protein complex subunit organization GO:0071822 302 0.190
macromolecule localization GO:0033036 252 0.184
membrane organization GO:0061024 94 0.171
establishment of organelle localization GO:0051656 37 0.171
regulation of ion transport GO:0043269 245 0.166
regulation of secretion by cell GO:1903530 208 0.159
signal release GO:0023061 145 0.157
negative regulation of calcium ion dependent exocytosis GO:0045955 5 0.157
lipid metabolic process GO:0006629 283 0.153
cellular lipid metabolic process GO:0044255 208 0.148
macromolecular complex assembly GO:0065003 273 0.146
protein complex biogenesis GO:0070271 263 0.135
regulation of neurotransmitter secretion GO:0046928 19 0.129
glycerolipid metabolic process GO:0046486 67 0.127
defecation GO:0030421 1 0.126
homeostatic process GO:0042592 331 0.125
neuron development GO:0048666 286 0.125
cellular component biogenesis GO:0044085 368 0.123
Fly
cation transmembrane transport GO:0098655 263 0.122
reproduction GO:0000003 245 0.114
Fly
neuron differentiation GO:0030182 368 0.110
axon development GO:0061564 96 0.107
calcium ion dependent exocytosis of neurotransmitter GO:0048791 2 0.106
regulation of exocytosis GO:0017157 37 0.104
gamma aminobutyric acid secretion GO:0014051 6 0.103
adult locomotory behavior GO:0008344 4 0.101
Fly
regulation of apoptotic process GO:0042981 335 0.098
neuromuscular synaptic transmission GO:0007274 2 0.097
protein oligomerization GO:0051259 191 0.096
regulation of nervous system development GO:0051960 264 0.095
Fly
secretion by cell GO:0032940 248 0.084
cellular chemical homeostasis GO:0055082 247 0.084
neuron neuron synaptic transmission GO:0007270 60 0.084
regulation of synaptic vesicle transport GO:1902803 6 0.082
intracellular signal transduction GO:0035556 314 0.080
acid secretion GO:0046717 48 0.080
positive regulation of synaptic transmission GO:0050806 62 0.079
cation homeostasis GO:0055080 195 0.079
male mating behavior GO:0060179 3 0.079
Fly
macromolecular complex subunit organization GO:0043933 339 0.078
programmed cell death GO:0012501 392 0.077
rhythmic synaptic transmission GO:0060024 1 0.076
organic hydroxy compound metabolic process GO:1901615 115 0.076
establishment of synaptic vesicle localization GO:0097480 23 0.075
cation transport GO:0006812 382 0.074
ion homeostasis GO:0050801 212 0.074
synapse organization GO:0050808 46 0.073
Fly
taxis GO:0042330 67 0.072
synaptic vesicle transport GO:0048489 23 0.071
carboxylic acid metabolic process GO:0019752 289 0.071
organic acid metabolic process GO:0006082 292 0.071
synaptic vesicle priming GO:0016082 4 0.071
g protein coupled receptor signaling pathway GO:0007186 242 0.070
regulation of neurogenesis GO:0050767 247 0.070
cellular macromolecule localization GO:0070727 122 0.069
protein complex assembly GO:0006461 263 0.069
cellular cation homeostasis GO:0030003 180 0.069
exocytosis GO:0006887 60 0.068
Fly
cellular metal ion homeostasis GO:0006875 172 0.068
multi organism reproductive process GO:0044703 262 0.068
Fly
oxoacid metabolic process GO:0043436 290 0.068
sexual reproduction GO:0019953 148 0.067
Fly
brain development GO:0007420 247 0.067
hormone transport GO:0009914 121 0.066
cellular component assembly GO:0022607 360 0.066
Fly
regulation of cellular localization GO:0060341 263 0.065
response to calcium ion GO:0051592 59 0.063
synaptic vesicle localization GO:0097479 24 0.062
hormone secretion GO:0046879 115 0.061
anion transport GO:0006820 178 0.060
glutamate receptor signaling pathway GO:0007215 43 0.059
regulation of cellular component organization GO:0051128 368 0.059
Fly
cell morphogenesis GO:0000902 142 0.059
regulation of neuron differentiation GO:0045664 208 0.059
anion transmembrane transport GO:0098656 77 0.058
response to ketone GO:1901654 182 0.057
regulation of neurotransmitter levels GO:0001505 42 0.057
chemical homeostasis GO:0048878 292 0.056
reproductive process GO:0022414 372 0.056
Fly
positive regulation of calcium ion dependent exocytosis GO:0045956 6 0.055
multicellular organismal reproductive process GO:0048609 233 0.055
Fly
vesicle organization GO:0016050 29 0.054
neurological system process GO:0050877 219 0.053
peptide hormone secretion GO:0030072 84 0.053
neuron projection morphogenesis GO:0048812 122 0.052
apoptotic process GO:0006915 381 0.052
inorganic ion transmembrane transport GO:0098660 229 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
Fly
positive regulation of multicellular organismal process GO:0051240 387 0.050
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.050
locomotion GO:0040011 237 0.050
single organism behavior GO:0044708 130 0.049
Fly
regulation of membrane potential GO:0042391 110 0.049
negative regulation of exocytosis GO:0045920 7 0.048
neuron projection development GO:0031175 273 0.048
organelle fusion GO:0048284 17 0.048
neurotransmitter transport GO:0006836 42 0.048
positive regulation of nervous system development GO:0051962 178 0.048
Fly
endoplasmic reticulum membrane organization GO:0090158 1 0.047
central nervous system development GO:0007417 311 0.047
protein localization GO:0008104 191 0.047
hormone metabolic process GO:0042445 69 0.047
positive regulation of exocytosis GO:0045921 19 0.046
organophosphate metabolic process GO:0019637 370 0.043
cellular protein localization GO:0034613 122 0.043
insulin secretion GO:0030073 69 0.042
regulation of neuron projection development GO:0010975 161 0.042
somatostatin receptor signaling pathway GO:0038169 4 0.042
regulation of hormone secretion GO:0046883 106 0.042
organelle organization GO:0006996 266 0.041
regulation of hormone levels GO:0010817 187 0.041
action potential GO:0001508 54 0.041
endoplasmic reticulum organization GO:0007029 1 0.041
intracellular transport GO:0046907 185 0.040
response to inorganic substance GO:0010035 377 0.040
ion transmembrane transport GO:0034220 365 0.039
regulation of vesicle mediated transport GO:0060627 81 0.039
positive regulation of secretion by cell GO:1903532 128 0.039
regulation of peptide hormone secretion GO:0090276 80 0.039
establishment of vesicle localization GO:0051650 31 0.039
vesicle fusion GO:0006906 14 0.038
lipid modification GO:0030258 52 0.037
endomembrane system organization GO:0010256 48 0.037
transmembrane transport GO:0055085 412 0.037
amide transport GO:0042886 105 0.037
detection of stimulus GO:0051606 24 0.037
Fly
axonogenesis GO:0007409 71 0.037
positive regulation of secretion GO:0051047 140 0.036
regulation of peptide secretion GO:0002791 82 0.036
cardiovascular system development GO:0072358 134 0.036
protein localization to membrane GO:0072657 36 0.036
multicellular organism reproduction GO:0032504 233 0.035
Fly
cognition GO:0050890 92 0.035
head development GO:0060322 247 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.034
metal ion homeostasis GO:0055065 186 0.034
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.034
synaptic transmission glutamatergic GO:0035249 33 0.034
sensory perception GO:0007600 101 0.032
negative regulation of gamma aminobutyric acid secretion GO:0014053 3 0.031
sensory perception of pain GO:0019233 73 0.031
synaptic vesicle endocytosis GO:0048488 4 0.031
cell projection morphogenesis GO:0048858 123 0.031
organelle localization GO:0051640 55 0.031
negative regulation of cellular component organization GO:0051129 83 0.030
mating GO:0007618 22 0.030
Fly
vesicle localization GO:0051648 33 0.030
synaptic transmission cholinergic GO:0007271 11 0.030
membrane fusion GO:0061025 26 0.030
negative regulation of secretion by cell GO:1903531 72 0.029
peptide secretion GO:0002790 86 0.029
protein phosphorylation GO:0006468 345 0.029
calcium ion dependent exocytosis GO:0017156 16 0.029
mechanoreceptor differentiation GO:0042490 2 0.028
protein transport GO:0015031 132 0.028
positive regulation of cell development GO:0010720 176 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of transcription dna templated GO:0006355 374 0.028
divalent inorganic cation homeostasis GO:0072507 165 0.028
membrane docking GO:0022406 6 0.028
regulation of lipid metabolic process GO:0019216 68 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
response to metal ion GO:0010038 253 0.027
regulation of axonogenesis GO:0050770 37 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.026
dendrite development GO:0016358 72 0.026
n methyl d aspartate receptor clustering GO:0097114 2 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
regulation of insulin secretion GO:0050796 65 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
regulation of protein metabolic process GO:0051246 289 0.025
regulation of cell differentiation GO:0045595 320 0.025
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
vesicle mediated transport GO:0016192 181 0.025
Fly
regulation of peptide transport GO:0090087 87 0.024
response to ammonium ion GO:0060359 71 0.024
response to histamine GO:0034776 3 0.024
regulation of neurotransmitter transport GO:0051588 21 0.024
protein homooligomerization GO:0051260 91 0.024
single organism reproductive process GO:0044702 297 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
response to nutrient levels GO:0031667 370 0.023
Worm
heart morphogenesis GO:0003007 3 0.023
cellular catabolic process GO:0044248 295 0.023
intracellular protein transport GO:0006886 79 0.023
regulation of rna metabolic process GO:0051252 391 0.023
dephosphorylation GO:0016311 98 0.023
regulation of organic acid transport GO:0032890 35 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
neuronal action potential GO:0019228 35 0.023
response to cytokine GO:0034097 215 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
Fly
regulation of cell development GO:0060284 263 0.022
positive regulation of cell communication GO:0010647 271 0.022
learning or memory GO:0007611 90 0.022
gamete generation GO:0007276 124 0.022
regulation of anion transport GO:0044070 43 0.022
axon guidance GO:0007411 24 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of amino acid transport GO:0051955 25 0.022
cellular homeostasis GO:0019725 252 0.022
aging GO:0007568 241 0.022
positive regulation of molecular function GO:0044093 230 0.022
multicellular organism growth GO:0035264 1 0.021
regulation of cell projection organization GO:0031344 175 0.021
growth GO:0040007 165 0.021
Fly
response to ethanol GO:0045471 162 0.021
sodium ion transmembrane transport GO:0035725 67 0.021
cellular component morphogenesis GO:0032989 155 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
Fly
cellular calcium ion homeostasis GO:0006874 160 0.021
regulation of programmed cell death GO:0043067 341 0.021
neurotransmitter gated ion channel clustering GO:0072578 3 0.020
negative regulation of transport GO:0051051 136 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
endocrine system development GO:0035270 30 0.020
nucleic acid templated transcription GO:0097659 379 0.020
second messenger mediated signaling GO:0019932 51 0.020
synaptic transmission glycinergic GO:0060012 2 0.020
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.020
amine metabolic process GO:0009308 38 0.020
single organism membrane fusion GO:0044801 17 0.020
amine transport GO:0015837 57 0.020
response to alkaloid GO:0043279 132 0.019
inflammatory response GO:0006954 150 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
negative regulation of cell death GO:0060548 229 0.019
response to toxic substance GO:0009636 133 0.019
regulation of molecular function GO:0065009 398 0.019
single organism biosynthetic process GO:0044711 342 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
phospholipid dephosphorylation GO:0046839 5 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
forebrain development GO:0030900 98 0.018
regulation of vesicle fusion GO:0031338 6 0.018
response to lipopolysaccharide GO:0032496 191 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
phospholipid metabolic process GO:0006644 61 0.018
positive regulation of gene expression GO:0010628 244 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
gland development GO:0048732 155 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
cell part morphogenesis GO:0032990 123 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
cellular protein complex assembly GO:0043623 44 0.018
negative regulation of secretion GO:0051048 82 0.018
response to decreased oxygen levels GO:0036293 237 0.017
synapse assembly GO:0007416 29 0.017
Fly
multicellular organismal signaling GO:0035637 44 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
protein autophosphorylation GO:0046777 66 0.017
calcium mediated signaling GO:0019722 23 0.017
response to insulin GO:0032868 133 0.017
response to bacterium GO:0009617 200 0.017
hair cell differentiation GO:0035315 2 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.017
developmental maturation GO:0021700 25 0.017
negative regulation of amino acid transport GO:0051956 13 0.016
establishment of protein localization GO:0045184 141 0.016
organic substance catabolic process GO:1901575 316 0.016
peptide transport GO:0015833 97 0.016
regulation of organelle organization GO:0033043 80 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
cell type specific apoptotic process GO:0097285 134 0.016
epithelium development GO:0060429 96 0.016
response to corticosteroid GO:0031960 235 0.016
rna biosynthetic process GO:0032774 380 0.016
regulation of cell proliferation GO:0042127 359 0.016
positive regulation of long term synaptic potentiation GO:1900273 4 0.016
oxidation reduction process GO:0055114 304 0.016
negative regulation of signaling GO:0023057 157 0.016
Worm
nucleoside metabolic process GO:0009116 179 0.015
cell projection organization GO:0030030 302 0.015
small molecule catabolic process GO:0044282 59 0.015
dicarboxylic acid transport GO:0006835 34 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of developmental process GO:0051094 283 0.015
Fly
negative regulation of multicellular organismal process GO:0051241 203 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
neuron projection guidance GO:0097485 24 0.015
cell migration GO:0016477 197 0.015
xenobiotic metabolic process GO:0006805 19 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
neuron death GO:0070997 127 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
peristalsis GO:0030432 2 0.015
retinal ganglion cell axon guidance GO:0031290 1 0.014
ensheathment of neurons GO:0007272 40 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
transmission of nerve impulse GO:0019226 42 0.014
protein heterooligomerization GO:0051291 89 0.014
negative regulation of nervous system development GO:0051961 79 0.014
single organism intracellular transport GO:1902582 166 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
Fly
detection of chemical stimulus GO:0009593 10 0.014
cellular ion homeostasis GO:0006873 184 0.014
cellular response to organonitrogen compound GO:0071417 197 0.013
learning GO:0007612 33 0.013
negative regulation of cell communication GO:0010648 158 0.013
Worm
glutamate secretion GO:0014047 19 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
locomotory behavior GO:0007626 15 0.013
Mouse Worm Fly
response to extracellular stimulus GO:0009991 380 0.013
Worm
regulation of neuron apoptotic process GO:0043523 83 0.013
positive regulation of synaptic vesicle transport GO:1902805 3 0.013
acute inflammatory response GO:0002526 58 0.013
embryonic pattern specification GO:0009880 1 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
axis specification GO:0009798 4 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
Fly
negative regulation of ion transport GO:0043271 51 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
calcium ion transport GO:0006816 131 0.013
negative regulation of synaptic transmission GO:0050805 29 0.013
tissue development GO:0009888 252 0.013
rna metabolic process GO:0016070 406 0.013
biological adhesion GO:0022610 110 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
neuron apoptotic process GO:0051402 88 0.012
positive regulation of vesicle fusion GO:0031340 4 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to nutrient GO:0007584 248 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
response to cocaine GO:0042220 39 0.012
vesicle docking GO:0048278 5 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
receptor localization to synapse GO:0097120 2 0.012
divalent inorganic cation transport GO:0072511 134 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
telencephalon development GO:0021537 62 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
rna localization GO:0006403 4 0.012
response to oxygen levels GO:0070482 265 0.012
somatostatin signaling pathway GO:0038170 4 0.012
limbic system development GO:0021761 38 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
Worm
positive regulation of biosynthetic process GO:0009891 319 0.012
olfactory behavior GO:0042048 2 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
membrane depolarization GO:0051899 32 0.011
heart development GO:0007507 72 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
alcohol metabolic process GO:0006066 77 0.011
nucleotide metabolic process GO:0009117 279 0.011
hexose metabolic process GO:0019318 58 0.011
liver development GO:0001889 90 0.011
actin filament based process GO:0030029 86 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
glycerophospholipid metabolic process GO:0006650 47 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
negative regulation of organic acid transport GO:0032891 14 0.011
positive regulation of creb transcription factor activity GO:0032793 2 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
negative regulation of metabolic process GO:0009892 331 0.011
response to camp GO:0051591 91 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
single organism catabolic process GO:0044712 283 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
detection of visible light GO:0009584 3 0.010
Fly
catabolic process GO:0009056 351 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
neuromuscular process GO:0050905 2 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
maintenance of location GO:0051235 17 0.010
negative regulation of glutamate secretion GO:0014050 9 0.010
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.010
nucleobase containing small molecule metabolic process GO:0055086 316 0.010
multi organism behavior GO:0051705 24 0.010
Fly
ras protein signal transduction GO:0007265 29 0.010
circulatory system development GO:0072359 134 0.010

Cacna1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.034
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
brain disease DOID:936 0 0.025
retinal disease DOID:5679 0 0.020
retinal degeneration DOID:8466 0 0.020
cone rod dystrophy DOID:0050572 0 0.020
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
epilepsy syndrome DOID:1826 0 0.017
substance dependence DOID:9973 0 0.012
substance related disorder DOID:303 0 0.012
disease of mental health DOID:150 0 0.012
electroclinical syndrome DOID:0050701 0 0.011