Rattus norvegicus

30 known processes

Cacna1e

calcium channel, voltage-dependent, R type, alpha 1E subunit

(Aliases: CACHA1E)

Cacna1e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.427
cellular response to endogenous stimulus GO:0071495 377 0.366
Worm
circulatory system process GO:0003013 183 0.325
Mouse Fly
inorganic ion transmembrane transport GO:0098660 229 0.271
inorganic cation transmembrane transport GO:0098662 202 0.203
cation transport GO:0006812 382 0.175
cation transmembrane transport GO:0098655 263 0.163
cell cell signaling GO:0007267 335 0.156
Mouse Rat Worm Fly
cellular response to organonitrogen compound GO:0071417 197 0.145
protein complex assembly GO:0006461 263 0.137
positive regulation of transport GO:0051050 245 0.134
Rat
cellular response to hormone stimulus GO:0032870 247 0.120
macromolecular complex assembly GO:0065003 273 0.119
nitrogen compound transport GO:0071705 229 0.115
Mouse
synaptic transmission GO:0007268 235 0.098
Rat Worm Fly
response to hypoxia GO:0001666 231 0.094
regulation of protein metabolic process GO:0051246 289 0.080
response to glucocorticoid GO:0051384 223 0.080
neuron differentiation GO:0030182 368 0.073
monovalent inorganic cation transport GO:0015672 172 0.073
cgmp biosynthetic process GO:0006182 15 0.073
oxoacid metabolic process GO:0043436 290 0.071
response to nutrient GO:0007584 248 0.069
regulation of multicellular organismal development GO:2000026 376 0.067
Fly
regulation of secretion by cell GO:1903530 208 0.066
Mouse Rat Fly
positive regulation of secretion GO:0051047 140 0.065
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.064
ion transmembrane transport GO:0034220 365 0.063
positive regulation of phosphorus metabolic process GO:0010562 262 0.061
macromolecular complex subunit organization GO:0043933 339 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.060
Fly
carboxylic acid metabolic process GO:0019752 289 0.059
sodium ion transport GO:0006814 82 0.055
response to carbohydrate GO:0009743 183 0.053
Mouse
response to hexose GO:0009746 144 0.053
Mouse
secretion GO:0046903 307 0.052
Mouse Rat Fly
hormone secretion GO:0046879 115 0.052
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.050
protein oligomerization GO:0051259 191 0.050
cellular component biogenesis GO:0044085 368 0.050
Fly
lipid metabolic process GO:0006629 283 0.050
response to mechanical stimulus GO:0009612 134 0.049
response to oxygen levels GO:0070482 265 0.045
positive regulation of developmental process GO:0051094 283 0.045
Fly
protein complex subunit organization GO:0071822 302 0.044
circadian rhythm GO:0007623 88 0.044
positive regulation of ion transport GO:0043270 94 0.044
calcium ion import GO:0070509 22 0.043
positive regulation of phosphorylation GO:0042327 177 0.042
metal ion transport GO:0030001 289 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
organic hydroxy compound transport GO:0015850 77 0.042
response to metal ion GO:0010038 253 0.042
positive regulation of cellular component organization GO:0051130 200 0.039
Fly
ion homeostasis GO:0050801 212 0.038
response to estrogen GO:0043627 232 0.037
negative regulation of cell death GO:0060548 229 0.037
cellular ion homeostasis GO:0006873 184 0.036
regulation of secretion GO:0051046 224 0.036
Mouse Rat Fly
organelle organization GO:0006996 266 0.036
sodium ion transmembrane transport GO:0035725 67 0.036
regulation of cell proliferation GO:0042127 359 0.035
regulation of cellular component organization GO:0051128 368 0.035
Fly
developmental growth GO:0048589 100 0.035
Fly
response to decreased oxygen levels GO:0036293 237 0.035
response to toxic substance GO:0009636 133 0.035
chemical homeostasis GO:0048878 292 0.035
Mouse
single organism biosynthetic process GO:0044711 342 0.034
response to extracellular stimulus GO:0009991 380 0.034
Worm
protein complex biogenesis GO:0070271 263 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
regulation of phosphate metabolic process GO:0019220 349 0.033
response to corticosteroid GO:0031960 235 0.033
response to inorganic substance GO:0010035 377 0.033
cell projection organization GO:0030030 302 0.032
intracellular signal transduction GO:0035556 314 0.032
regulation of neurogenesis GO:0050767 247 0.032
growth GO:0040007 165 0.032
Fly
regulation of ion transport GO:0043269 245 0.031
positive regulation of secretion by cell GO:1903532 128 0.030
Rat
homeostatic process GO:0042592 331 0.030
Mouse
response to radiation GO:0009314 137 0.030
Mouse Fly
acid secretion GO:0046717 48 0.029
regulation of cellular localization GO:0060341 263 0.029
Mouse Rat Fly
response to glucose GO:0009749 136 0.029
Mouse
positive regulation of signaling GO:0023056 270 0.029
Rat
positive regulation of cell projection organization GO:0031346 111 0.029
cellular component assembly GO:0022607 360 0.028
Fly
cellular response to peptide GO:1901653 133 0.028
response to monosaccharide GO:0034284 159 0.028
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
phosphatidylinositol dephosphorylation GO:0046856 4 0.027
anion transport GO:0006820 178 0.027
cellular response to alcohol GO:0097306 87 0.027
wound healing GO:0042060 122 0.027
anion transmembrane transport GO:0098656 77 0.027
brain development GO:0007420 247 0.027
regulation of molecular function GO:0065009 398 0.026
membrane depolarization during action potential GO:0086010 1 0.026
regulation of phosphorylation GO:0042325 248 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of peptide transport GO:0090087 87 0.026
Mouse
regulation of defecation GO:2000292 1 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular response to stress GO:0033554 269 0.025
protein heterooligomerization GO:0051291 89 0.025
protein phosphorylation GO:0006468 345 0.025
positive regulation of cell development GO:0010720 176 0.024
negative regulation of metabolic process GO:0009892 331 0.024
response to nutrient levels GO:0031667 370 0.024
Worm
response to growth factor GO:0070848 189 0.024
Worm
response to retinoic acid GO:0032526 63 0.024
neuron projection development GO:0031175 273 0.024
cellular homeostasis GO:0019725 252 0.023
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
blood circulation GO:0008015 183 0.022
Mouse Fly
negative regulation of cell proliferation GO:0008285 119 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
multicellular organism growth GO:0035264 1 0.022
negative regulation of calcium ion import GO:0090281 2 0.022
regulation of blood vessel size GO:0050880 89 0.022
secretion by cell GO:0032940 248 0.022
Mouse Rat Fly
regulation of follicle stimulating hormone secretion GO:0046880 5 0.021
neuron projection morphogenesis GO:0048812 122 0.021
regulation of catalytic activity GO:0050790 304 0.021
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
amine transport GO:0015837 57 0.020
endocytosis GO:0006897 84 0.020
regulation of anatomical structure size GO:0090066 135 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
neurotransmitter secretion GO:0007269 33 0.020
Rat Fly
regulation of synaptic plasticity GO:0048167 70 0.020
nucleic acid templated transcription GO:0097659 379 0.020
amine metabolic process GO:0009308 38 0.020
programmed cell death GO:0012501 392 0.020
mapk cascade GO:0000165 140 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
response to ethanol GO:0045471 162 0.019
Rat
glycerolipid metabolic process GO:0046486 67 0.019
organic anion transport GO:0015711 132 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
choline transport GO:0015871 4 0.019
hair follicle development GO:0001942 2 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
Mouse
carboxylic acid transport GO:0046942 115 0.018
positive regulation of cell communication GO:0010647 271 0.018
Rat
regulation of lipid metabolic process GO:0019216 68 0.018
multicellular organismal signaling GO:0035637 44 0.018
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.018
cellular amine metabolic process GO:0044106 38 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
positive regulation of serotonin secretion GO:0014064 1 0.018
negative regulation of defecation GO:2000293 1 0.018
regulation of behavior GO:0050795 61 0.018
response to molecule of bacterial origin GO:0002237 194 0.017
regeneration GO:0031099 163 0.017
reproduction GO:0000003 245 0.017
Fly
regulation of system process GO:0044057 208 0.017
Mouse Fly
sequestering of calcium ion GO:0051208 8 0.017
response to other organism GO:0051707 220 0.017
organ regeneration GO:0031100 101 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
insulin secretion GO:0030073 69 0.017
Mouse
regulation of protein phosphorylation GO:0001932 183 0.017
response to biotic stimulus GO:0009607 226 0.017
behavior GO:0007610 205 0.017
Mouse Worm Fly
protein homooligomerization GO:0051260 91 0.017
striated muscle contraction GO:0006941 44 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
muscle system process GO:0003012 115 0.016
defense response GO:0006952 194 0.016
Mouse
response to peptide hormone GO:0043434 278 0.016
locomotory exploration behavior GO:0035641 1 0.016
response to estradiol GO:0032355 164 0.016
purine containing compound biosynthetic process GO:0072522 85 0.016
potassium ion transmembrane transport GO:0071805 71 0.016
regulation of nervous system development GO:0051960 264 0.016
Fly
regulation of rna biosynthetic process GO:2001141 381 0.016
regulation of synaptic transmission GO:0050804 141 0.016
Rat Fly
regulation of membrane potential GO:0042391 110 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
intracellular transport GO:0046907 185 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
reproductive process GO:0022414 372 0.015
Fly
organic substance catabolic process GO:1901575 316 0.015
neuron death GO:0070997 127 0.015
defecation GO:0030421 1 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
intracellular protein transport GO:0006886 79 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
potassium ion transport GO:0006813 97 0.015
positive regulation of cell motility GO:2000147 97 0.015
adaptation of signaling pathway GO:0023058 10 0.015
rhythmic process GO:0048511 156 0.015
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.014
proteolysis GO:0006508 175 0.014
organophosphate metabolic process GO:0019637 370 0.014
regulation of cell projection organization GO:0031344 175 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
cellular cation homeostasis GO:0030003 180 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.014
neuron development GO:0048666 286 0.014
cyclic nucleotide biosynthetic process GO:0009190 63 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.014
transmission of nerve impulse GO:0019226 42 0.014
Mouse
central nervous system development GO:0007417 311 0.014
cellular response to oxygen levels GO:0071453 60 0.014
response to cocaine GO:0042220 39 0.014
regulation of neuron projection development GO:0010975 161 0.014
response to ketone GO:1901654 182 0.014
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
neurological system process GO:0050877 219 0.013
Mouse Rat Fly
calcium ion homeostasis GO:0055074 162 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
single organism organelle organization GO:1902589 180 0.013
monoamine transport GO:0015844 43 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
positive regulation of signal transduction GO:0009967 175 0.013
tissue development GO:0009888 252 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
response to calcium ion GO:0051592 59 0.013
phospholipid metabolic process GO:0006644 61 0.013
positive regulation of molecular function GO:0044093 230 0.013
actin filament based process GO:0030029 86 0.013
sequestering of metal ion GO:0051238 9 0.012
macromolecule localization GO:0033036 252 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
regulation of cell development GO:0060284 263 0.012
regulation of protein kinase activity GO:0045859 105 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
cellular chemical homeostasis GO:0055082 247 0.012
Mouse
amide transport GO:0042886 105 0.012
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.012
response to acid chemical GO:0001101 222 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
vesicle mediated transport GO:0016192 181 0.012
Fly
multicellular organism reproduction GO:0032504 233 0.012
Fly
regulation of mapk cascade GO:0043408 116 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of exocytosis GO:0045921 19 0.012
regulation of ion homeostasis GO:2000021 63 0.012
rna biosynthetic process GO:0032774 380 0.012
nucleotide metabolic process GO:0009117 279 0.012
macromolecule catabolic process GO:0009057 58 0.012
regulation of neutrophil apoptotic process GO:0033029 4 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
organic acid metabolic process GO:0006082 292 0.012
vasodilation GO:0042311 44 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
response to hyperoxia GO:0055093 45 0.012
organelle localization GO:0051640 55 0.012
cellular response to hypoxia GO:0071456 51 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
cardiac muscle contraction GO:0060048 27 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
regulation of smooth muscle contraction GO:0006940 29 0.011
positive regulation of protein modification process GO:0031401 142 0.011
metal ion homeostasis GO:0055065 186 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of immune system process GO:0002682 123 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
gastric inhibitory peptide signaling pathway GO:0038192 1 0.011
response to electrical stimulus GO:0051602 56 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
response to peptide GO:1901652 292 0.011
lipid transport GO:0006869 61 0.011
regulation of cell differentiation GO:0045595 320 0.011
circulatory system development GO:0072359 134 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
behavioral response to nicotine GO:0035095 2 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
dephosphorylation GO:0016311 98 0.011
action potential GO:0001508 54 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
catecholamine secretion GO:0050432 33 0.010
lipid localization GO:0010876 62 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
ras protein signal transduction GO:0007265 29 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
Fly
regulation of membrane repolarization GO:0060306 1 0.010
positive regulation of nervous system development GO:0051962 178 0.010
Fly
purine containing compound metabolic process GO:0072521 253 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
cellular glucose homeostasis GO:0001678 66 0.010
Mouse
maintenance of location GO:0051235 17 0.010

Cacna1e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011