Rattus norvegicus

0 known processes

Calhm2

calcium homeostasis modulator 2

(Aliases: Fam26b,MGC105861,RGD1308276)

Calhm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.212
programmed cell death GO:0012501 392 0.194
regulation of rna metabolic process GO:0051252 391 0.193
positive regulation of biosynthetic process GO:0009891 319 0.189
positive regulation of cell proliferation GO:0008284 249 0.180
rna biosynthetic process GO:0032774 380 0.143
regulation of cell proliferation GO:0042127 359 0.122
regulation of nucleic acid templated transcription GO:1903506 380 0.121
regulation of molecular function GO:0065009 398 0.114
regulation of rna biosynthetic process GO:2001141 381 0.113
rna metabolic process GO:0016070 406 0.110
positive regulation of developmental process GO:0051094 283 0.104
regulation of programmed cell death GO:0043067 341 0.103
oxoacid metabolic process GO:0043436 290 0.102
regulation of signal transduction GO:0009966 318 0.097
organophosphate metabolic process GO:0019637 370 0.090
positive regulation of multicellular organismal process GO:0051240 387 0.090
positive regulation of cell differentiation GO:0045597 217 0.086
positive regulation of cellular biosynthetic process GO:0031328 295 0.086
negative regulation of biosynthetic process GO:0009890 168 0.081
organic acid metabolic process GO:0006082 292 0.080
regulation of phosphate metabolic process GO:0019220 349 0.080
carboxylic acid metabolic process GO:0019752 289 0.079
intracellular signal transduction GO:0035556 314 0.078
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.078
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
negative regulation of cellular metabolic process GO:0031324 281 0.070
regulation of cellular protein metabolic process GO:0032268 267 0.070
response to oxygen levels GO:0070482 265 0.070
negative regulation of metabolic process GO:0009892 331 0.069
immune response GO:0006955 104 0.067
nucleobase containing small molecule metabolic process GO:0055086 316 0.065
transcription dna templated GO:0006351 377 0.063
response to other organism GO:0051707 220 0.063
regulation of catalytic activity GO:0050790 304 0.063
positive regulation of phosphate metabolic process GO:0045937 262 0.062
transcription from rna polymerase ii promoter GO:0006366 252 0.062
cellular response to lipid GO:0071396 201 0.061
immune system process GO:0002376 204 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.058
regulation of cellular ketone metabolic process GO:0010565 27 0.058
regulation of apoptotic process GO:0042981 335 0.058
regulation of transcription dna templated GO:0006355 374 0.057
regulation of multicellular organismal development GO:2000026 376 0.056
nucleotide metabolic process GO:0009117 279 0.056
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.056
regulation of cell development GO:0060284 263 0.055
nucleoside phosphate metabolic process GO:0006753 283 0.055
cellular amino acid metabolic process GO:0006520 107 0.054
positive regulation of gene expression GO:0010628 244 0.054
positive regulation of cell death GO:0010942 184 0.052
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.052
regulation of immune response GO:0050776 55 0.051
negative regulation of macromolecule metabolic process GO:0010605 260 0.051
organic substance catabolic process GO:1901575 316 0.049
tube development GO:0035295 89 0.048
leukocyte activation GO:0045321 76 0.048
monocarboxylic acid metabolic process GO:0032787 152 0.047
regulation of cell differentiation GO:0045595 320 0.046
protein phosphorylation GO:0006468 345 0.046
purine ribonucleotide metabolic process GO:0009150 227 0.045
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
negative regulation of rna biosynthetic process GO:1902679 118 0.042
regulation of protein metabolic process GO:0051246 289 0.041
regulation of protein modification process GO:0031399 194 0.039
immune effector process GO:0002252 53 0.039
cellular response to external stimulus GO:0071496 118 0.039
regulation of hydrolase activity GO:0051336 143 0.039
positive regulation of molecular function GO:0044093 230 0.038
regulation of interleukin 6 production GO:0032675 12 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
fatty acid metabolic process GO:0006631 99 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.037
apoptotic process GO:0006915 381 0.037
positive regulation of mapk cascade GO:0043410 92 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
female pregnancy GO:0007565 122 0.035
cell migration GO:0016477 197 0.035
gland development GO:0048732 155 0.034
cellular lipid metabolic process GO:0044255 208 0.034
catabolic process GO:0009056 351 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
cell chemotaxis GO:0060326 31 0.034
regulation of leukocyte activation GO:0002694 45 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cell activation GO:0001775 97 0.033
response to estradiol GO:0032355 164 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.032
respiratory system development GO:0060541 45 0.032
negative regulation of nucleic acid templated transcription GO:1903507 117 0.032
fatty acid derivative metabolic process GO:1901568 38 0.032
cellular response to steroid hormone stimulus GO:0071383 93 0.032
positive regulation of cell activation GO:0050867 34 0.032
regulation of phosphorylation GO:0042325 248 0.031
response to mechanical stimulus GO:0009612 134 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
positive regulation of programmed cell death GO:0043068 157 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
negative regulation of innate immune response GO:0045824 4 0.029
bmp signaling pathway GO:0030509 4 0.029
response to corticosteroid GO:0031960 235 0.029
negative regulation of rna metabolic process GO:0051253 123 0.029
positive regulation of cell development GO:0010720 176 0.029
nucleic acid templated transcription GO:0097659 379 0.029
lipid metabolic process GO:0006629 283 0.028
cytokine production GO:0001816 61 0.028
response to cytokine GO:0034097 215 0.028
response to bacterium GO:0009617 200 0.028
head development GO:0060322 247 0.028
cellular component movement GO:0006928 248 0.028
signal transduction by phosphorylation GO:0023014 144 0.028
lymphocyte activation GO:0046649 43 0.028
purine nucleoside metabolic process GO:0042278 169 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
nucleotide catabolic process GO:0009166 139 0.027
response to wounding GO:0009611 254 0.027
negative regulation of cell death GO:0060548 229 0.027
regulation of immune system process GO:0002682 123 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
negative regulation of cell differentiation GO:0045596 99 0.026
localization of cell GO:0051674 202 0.026
reproductive process GO:0022414 372 0.026
response to growth factor GO:0070848 189 0.025
cellular amine metabolic process GO:0044106 38 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
cellular catabolic process GO:0044248 295 0.025
purine containing compound metabolic process GO:0072521 253 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
axis specification GO:0009798 4 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
regulation of blood circulation GO:1903522 110 0.025
locomotion GO:0040011 237 0.025
oxidation reduction process GO:0055114 304 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
regulation of cell activation GO:0050865 50 0.024
cellular ketone metabolic process GO:0042180 51 0.024
single organism biosynthetic process GO:0044711 342 0.024
response to hypoxia GO:0001666 231 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
positive regulation of apoptotic process GO:0043065 154 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
response to metal ion GO:0010038 253 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
single organism catabolic process GO:0044712 283 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of transcription dna templated GO:0045892 116 0.022
regulation of neurogenesis GO:0050767 247 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
response to estrogen GO:0043627 232 0.022
response to decreased oxygen levels GO:0036293 237 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
positive regulation of protein modification process GO:0031401 142 0.022
positive regulation of signaling GO:0023056 270 0.022
unsaturated fatty acid metabolic process GO:0033559 39 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
tissue development GO:0009888 252 0.022
cell motility GO:0048870 202 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
purine nucleotide catabolic process GO:0006195 136 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
peptidyl amino acid modification GO:0018193 126 0.021
nucleoside catabolic process GO:0009164 126 0.021
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
brain development GO:0007420 247 0.021
regulation of cellular component movement GO:0051270 150 0.021
response to inorganic substance GO:0010035 377 0.020
protein localization GO:0008104 191 0.020
cellular response to mechanical stimulus GO:0071260 48 0.020
protein complex assembly GO:0006461 263 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of immune response GO:0050778 42 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of nervous system development GO:0051960 264 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
cellular response to stress GO:0033554 269 0.019
macromolecule localization GO:0033036 252 0.019
leukocyte mediated immunity GO:0002443 28 0.019
regulation of cellular localization GO:0060341 263 0.019
cellular response to lipopolysaccharide GO:0071222 55 0.019
single organism reproductive process GO:0044702 297 0.019
response to glucose GO:0009749 136 0.019
positive regulation of intracellular protein transport GO:0090316 20 0.019
establishment of protein localization GO:0045184 141 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
purine containing compound catabolic process GO:0072523 138 0.018
regulation of mapk cascade GO:0043408 116 0.018
response to lipopolysaccharide GO:0032496 191 0.018
protein complex subunit organization GO:0071822 302 0.018
blood circulation GO:0008015 183 0.018
central nervous system development GO:0007417 311 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
response to acid chemical GO:0001101 222 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
response to toxic substance GO:0009636 133 0.018
regulation of cell motility GO:2000145 131 0.017
response to ketone GO:1901654 182 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
response to carbohydrate GO:0009743 183 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
regulation of locomotion GO:0040012 148 0.017
multicellular organismal homeostasis GO:0048871 49 0.017
macromolecular complex assembly GO:0065003 273 0.017
protein oligomerization GO:0051259 191 0.017
urogenital system development GO:0001655 78 0.017
salivary gland development GO:0007431 3 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
tissue remodeling GO:0048771 40 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.016
organ morphogenesis GO:0009887 75 0.016
innate immune response GO:0045087 35 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
cellular component assembly GO:0022607 360 0.016
regulation of neuron death GO:1901214 115 0.016
multi organism reproductive process GO:0044703 262 0.016
response to monosaccharide GO:0034284 159 0.016
muscle contraction GO:0006936 88 0.016
cytoplasmic transport GO:0016482 115 0.016
growth GO:0040007 165 0.016
regulation of system process GO:0044057 208 0.016
behavior GO:0007610 205 0.016
positive regulation of cytokine production GO:0001819 42 0.016
response to hexose GO:0009746 144 0.015
regulation of hormone levels GO:0010817 187 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
response to glucocorticoid GO:0051384 223 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
regulation of cellular component organization GO:0051128 368 0.015
positive regulation of immune system process GO:0002684 90 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
regulation of stem cell differentiation GO:2000736 2 0.015
multicellular organism reproduction GO:0032504 233 0.015
anterior posterior pattern specification GO:0009952 1 0.015
icosanoid metabolic process GO:0006690 38 0.014
regulation of muscle contraction GO:0006937 53 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
heterocycle catabolic process GO:0046700 167 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of response to external stimulus GO:0032101 106 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
positive regulation of nervous system development GO:0051962 178 0.014
calcium ion transport GO:0006816 131 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
metanephric mesenchymal cell migration GO:0035789 2 0.014
multi multicellular organism process GO:0044706 138 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
positive regulation of signal transduction GO:0009967 175 0.013
positive regulation of cell communication GO:0010647 271 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
regulation of bmp signaling pathway GO:0030510 2 0.013
regulation of striated muscle contraction GO:0006942 21 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
regulation of response to wounding GO:1903034 69 0.013
proteolysis GO:0006508 175 0.013
gtp catabolic process GO:0006184 71 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
cytokine biosynthetic process GO:0042089 3 0.013
liver development GO:0001889 90 0.013
anatomical structure morphogenesis GO:0009653 298 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
nucleoside metabolic process GO:0009116 179 0.012
cellular component biogenesis GO:0044085 368 0.012
regulation of anatomical structure size GO:0090066 135 0.012
cell growth GO:0016049 104 0.012
regulation of cell cycle GO:0051726 73 0.012
alcohol metabolic process GO:0006066 77 0.012
adult locomotory behavior GO:0008344 4 0.012
secretion by cell GO:0032940 248 0.012
response to anoxia GO:0034059 4 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
icosanoid biosynthetic process GO:0046456 18 0.012
regulation of response to stress GO:0080134 126 0.012
response to peptide GO:1901652 292 0.012
response to external biotic stimulus GO:0043207 221 0.012
chemotaxis GO:0006935 66 0.012
mapk cascade GO:0000165 140 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
lung development GO:0030324 43 0.011
embryo implantation GO:0007566 15 0.011
positive regulation of leukocyte activation GO:0002696 30 0.011
gliogenesis GO:0042063 93 0.011
sequestering of metal ion GO:0051238 9 0.011
neuron projection development GO:0031175 273 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
regulation of secretion by cell GO:1903530 208 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of immune system process GO:0002683 39 0.011
positive regulation of protein transport GO:0051222 41 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
b cell mediated immunity GO:0019724 4 0.011
response to oxidative stress GO:0006979 186 0.011
response to peptide hormone GO:0043434 278 0.011
neuron development GO:0048666 286 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.011
circulatory system development GO:0072359 134 0.011
artery development GO:0060840 3 0.011
organophosphate catabolic process GO:0046434 148 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
defense response GO:0006952 194 0.011
aromatic compound catabolic process GO:0019439 168 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of chemotaxis GO:0050920 29 0.010
regulation of smooth muscle contraction GO:0006940 29 0.010
regulation of cell growth GO:0001558 85 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
extracellular matrix constituent secretion GO:0070278 4 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
cellular chemical homeostasis GO:0055082 247 0.010
regulation of protein transport GO:0051223 68 0.010
divalent inorganic cation transport GO:0072511 134 0.010
rhythmic process GO:0048511 156 0.010
myeloid leukocyte activation GO:0002274 36 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
gonad development GO:0008406 104 0.010
comma shaped body morphogenesis GO:0072049 2 0.010
glomerular mesangial cell proliferation GO:0072110 4 0.010
response to ethanol GO:0045471 162 0.010

Calhm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
retinal disease DOID:5679 0 0.014
eye disease DOID:5614 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
retinal degeneration DOID:8466 0 0.013
central nervous system disease DOID:331 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
colon cancer DOID:219 0 0.011
large intestine cancer DOID:5672 0 0.011
colorectal cancer DOID:9256 0 0.011
colon carcinoma DOID:1520 0 0.011
intestinal cancer DOID:10155 0 0.011